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7319520 Method for separating fluorescence spectra of dyes present in a sample  
A system and a method for setting a fluorescence spectrum measurement system for microscopy is disclosed. Using illuminating light (3) from at least one laser that emits light of one wavelength, a...
7319039 Aerosol-based detection of biological agents  
The presence of an aerosol or cloud (3) of a toxic substance is detected by producing an aerosol (17, 5) of ligands (13) to the target substance in a region of sky that contains the target...
7317194 Microscope for performing multiple frequency fluorometric measurements  
An optical imager, such as a microscope for performing multiple frequency fluorometric measurements comprising a light source, such as a laser source is disclosed. The system is used to excite a...
7317515 Method of localizing fluorescent markers  
The invention describes a method of determining the position of fluorescent markers in a sample (4), with a high spatial resolution. To this end, the sample (4) is illuminated with an exciting...
7315357 Imaging and analyzing parameters of small moving objects such as cells  
Light from an object such as a cell moving through an imaging system is collected and dispersed so that it is imaged onto a plurality of separate detectors. The light is spectrally dispersed by a...
7310142 Fast time-correlated multi-element photon detector and method  
Photons emitted from a sample responsive to being excited by laser pulses are directed through a prism onto a photomultiplier tube having several spaced-apart anodes. The prism alters the path of...
7307705 Method and apparatus for compact dispersive imaging spectrometer  
The disclosure generally relates to a method and apparatus for compact dispersive imaging spectrometer. More specifically, one embodiment of the disclosure relates to a portable system for...
7297963 Method for determination of fuel thermal stability  
A method of evaluating thermal stability of a fuel and an apparatus used therein. The method includes heating the fuel to a given temperature, directing light through the heated fuel a first time...
7298476 Method and system for far-field microscopy to exceeding diffraction-limit resolution  
The bio-sample (e.g., a live cell) is labeled with a proper number of nanoparticles. Each nanoparticle is pre-co-doped with a controlled ratio of fluorophore donors and acceptors. Two laser pulses...
7297962 Method for performing spacially coordinated high speed fluorometric measurements  
An optical imager, such as a microscope for performing multiple frequency fluorometric measurements comprising a light source, such as a laser source is disclosed. The system is used to excite a...
7298475 Method and apparatus for stand-off chemical detection  
A method, suitable for stand off analysis of a sample (2), comprising: (i) using an excitation means (6) to vaporise the sample (2) thereby producing a vapour plume (10) of molecular species; and...
7289207 Integrated optical biosensor system (IOBS)  
An optical biosensor has a first enclosure with a pathogen recognition surface, including a planar optical waveguide and grating located in the first enclosure. An aperture is in the first...
7286225 Optical fiber type spectroscope and spectroscope system equipped therewith  
A spectroscope includes an optical fiber 218, a collimator optical system 231 for collimating signal light come out from the optical fiber 218, a spectroscopic element 233 for dispersing the...
7286223 Method and apparatus for detecting embedded rebar within an interaction region of a structure irradiated with laser light  
A detection system is used during irradiation of an interaction region of a structure with laser light. The structure includes embedded material. The detection system includes a focusing lens...
7286224 Time-multiplexed scanning light source for multi-probe, multi-laser fluorescence detection systems  
An apparatus images a surface. An imager stage linearly translates the surface in a first direction. A light path has a first end defining an input aperture perpendicular to the first direction...
7283223 Cytometer having telecentric optics  
A mechanism for moving and positioning a light source so that its light impinges a target as it moves on or off axis of an optical system. A detector may receive scattered light at a same position...
7280204 Multi-spectral detector and analysis system  
A multi-spectral detection and analysis system detects and classifies a targeted sample. The system may include a light source that causes the targeted sample to luminesce. A light dispersion...
7271898 Method and system for remote sensing of optical instruments and analysis thereof  
A sensor is provided for analyzing an object at a focal point of a lens. The sensor includes a focused radiant energy source directed at the lens. The focused radiant energy source transmits a...
7267457 Method for detecting forensic evidence  
A method for detecting forensic evidence. The method includes use of a forensic light that may utilize a variety of semiconductor light sources to produce light that contrasts forensic evidence...
7268868 Anti-resonant waveguide sensors  
An improved method of analyzing target analytes in a sample is described. The method is based on anti-resonant guided optical waveguides which enables a strongly improved light-target interaction...
7265825 Apparatus for measuring fluorescence lifetime  
An apparatus for measuring fluorescence lifetime includes a pulse laser source that generates a pulse excitation light, a detector that detects a fluorescence generated from a sample by...
7262839 Method and apparatus for compact birefringent interference imaging spectrometer  
The disclosure relates to a method and apparatus for a compact birefringent interference imaging spectrometer. More specifically, the disclosure relates to a portable system for obtaining a...
7259847 Use of optical diffraction elements in detection methods  
The invention relates to a method for determining luminescent molecules by means of optical excitation in confocal measurement volumes using a diffractive optical element. The method is...
7256887 Determining the suitability of an optical material for the production of optical elements, corresponding device, and use of said material  
The method tests the suitability of an optical material having a radiation-induced absorption, especially of an alkali or alkaline earth halide, for production of an optical element exposed to...
7251022 Dual fiber microprobe for mapping elemental distributions in biological cells  
Laser-induced breakdown spectroscopy (LIBS) is applied on a microscale for in situ elemental analysis and spatial mapping in biological cells. A high power laser beam is focused onto a cell...
7248360 Polychronic laser scanning system and method of use  
A system for laser scanning provides spectral flexibility needed for the spectroscopic monitoring of highly multiplexed samples, such as cellular and particle assays in whole blood or other...
7247443 Sensor constructs and detection methods  
Sensor constructs for detecting the presence of an analyte in a sample comprise a molecular scaffold, a pair of labels which interact via Förster resonance energy transfer, and at least one...
7248361 Fluorescence reader based on anti-resonant waveguide excitation  
A sample detection system including an anti-resonant waveguide, including a sample having a first index of refraction, a top layer and a substrate surrounding the sample, where the top layer has a...
7245369 Spectroscopic apparatus using spectrum narrowed and stabilized laser with Bragg grating  
An apparatus for measuring properties of physical matters by means of Raman spectroscopy including a laser element, a wavelength dispersion element, an array or single element detector, and a...
7245371 Laser curing apparatus with real-time monitoring and control  
In a laser based curing apparatus, the acts both as the curing light and the excitation source for a Raman spectroscopic sensor. The spectroscopic sensor provides real-time, in situ, non-invasive...
7233392 Spectral imaging device with tunable light source  
A spectral imaging device with a narrow band spectrally tunable light source. The light source includes an optical parametric oscillator that can be tuned across a wide range of wavelengths while...
7227643 Surface plasmon excitation device and microscope including the same  
A device for exciting surface plasmons includes a light illuminating source, a transparent substrate having a ridge, a metal layer covering side surfaces of the ridge and their neighboring region,...
7223232 Endoscope probe system having confocal optical systems  
An endoscope probe system includes an endoscope probe to be inserted into a body cavity to observe tissue of a living body. The endoscope probe system further includes a laser source that emits...
7221450 Dual wavelength optical analyser  
An optical device for directing optical signals in a fluorescence-based analyzer having first and second laser light sources for providing illuminating laser light at different wavelengths. The...
7218396 Method and apparatus for spectroscopy of the optical emission of a liquid excited by a laser  
A method for spectroscopy of the optical emission of a liquid excited by a pulsed laser focused on the surface thereof is such that the area of analysis is scanned by a laminar discharge of gas...
7215421 Fluorescence lifetime measurement apparatus  
A fluorescence lifetime measurement apparatus includes a first controller controlling a total gate length and a second controller controlling a start gate length of a plurality of gate lengths...
7209223 Optical device for measuring optical properties of a sample and method relating thereto  
A device and method for measuring optical properties of a sample are provided. The device comprises a housing surrounding a flow-through flow-cell having a sample inlet positioned proximate to a...
7202948 LIBS system and method for engine exhaust monitoring  
A trace species detection system for engine health monitoring, the system including a laser for generating a laser beam, and optics for focusing the laser beam into an exhaust plume of an engine...
7201879 Aerosol into liquid collector for depositing particles from a large volume of gas into a small volume of liquid  
An aerosol-into-liquid collector (ALC) for collecting gas-borne particles from a large volume of gas such as air into a small volume of liquid is described. The ALC uses a linear quadrupole to...
7201878 Aerosol particle analyzer for measuring an analyte in airborne particles  
Aerosol particle analyzer (APA) for measuring an analyte in airborne particle is described. Airborne particles are first given an electrical charge and then drawn in air past an oppositely charged...
7195731 Method for preparing and processing a sample for intensive analysis  
This application relates to a method for pellerizing and taking intensive measurements of a raw sample. The method includes homogenizing and pelletizing the sample that is to be subjected to...
7196787 Apparatus for total internal reflection microscopy  
An apparatus for total internal reflection microscopy of a sample, comprising a microscope objective lens; an excitation beam path for passing light through the objective lens to said sample; and...
7192783 Stokes shift emission spectroscopy for detection of disease and physiological state of specimen  
The Stokes shift emission spectra were measured for various samples, including tissues containing photoactive bio-molecules such as tryptophan, elastin, collagen, NADH and flavin. This new...
7190450 Systems and methods for sorting aerosols  
An aerosol deflection system having a concentration zone expelling an air stream through a first detection zone, a second detection zone, and a deflection zone. The first detection zone activates...
7184143 Method for remote sensing of pollutant molecules in a transparent medium using ultra-short intense lasers  
There is described a method for identifying at least one molecule in a substantially transparent medium, the method comprising: transmitting high-power, ultra-short laser pulses into the medium so...
7180589 Luminescence measuring device with pre-filter effect suppression  
A device for measuring the intensity of a luminescence radiation emitted by at least one chemical species probed, along a trajectory by an excitation radiation. The device includes n measurement...
7180661 Confocal scanning microscope  
A confocal scanning microscope includes a stimulating light beam scanning unit that scans at least a predetermined plane perpendicular to the depth direction of the stimulating light beam focal...
7170597 Microplate reader  
A method and apparatus for the measurement of radiation, especially fluorescence from samples in assays, wherein a plurality of micro-sample light emitting sites are imaged simultaneously onto a...
7170598 Multi-parameter fluorimetric analysis in a massively parallel multi-focal arrangement and the use thereof  
A method for analyzing properties of a sample by measuring fluorescence parameters in multiple foci, comprises the steps of splitting a collimated primary laser beam with a splitting device into...
7166475 Compositions and methods for monitoring the modification state of a pair of polypeptides  
This invention relates to a method for analyzing a sample comprising: immobilising a polypeptide to a physical support; contacting the immobilised polypeptide with a test sample which may contain...