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5480775 |
Method for measuring a specimen by the use of fluorescent light
A method of and an apparatus for measuring a specimen by the use of fluorescence light which has the step of dyeing the specimen with a fluorescence dye, the step of applying light to the dyed...
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5478755 |
Long range surface plasma resonance immunoassay
A method of assaying for a ligand in a sample involves incubating the sample in contact with a specific binding partner for the ligand carried on one surface of an optical structure, irradiating...
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5469255 |
Method and apparatus for spectrometric measurement of particulate surfaces
A method of spectrometry is disclosed for measuring transient absorbance and transient absorption spectrum of a substance to be measured at interfaces in liquid phase of particulates containing a...
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5459325 |
High-speed fluorescence scanner
A high-speed fluorescence scanner for scanning a sample at equal angles is disclosed. The scanner has most of its optical components, including a light beam source, a detector, and various filters,...
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5459567 |
Method for determining the degree of spectral interference in an assay having a test sample
A method to determine the degree of spectral interference in an assay containing a test sample in which a graph plot of efficiency versus ratio of a fluorescence label is a known standard. The...
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5455674 |
Method and apparatus for forensic examination of surfaces
A method of illuminating a deposition of organic material such as, blood, sweat or oil for forensic examination is disclosed. Light having a wide range of wavelengths is generated and directed...
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5452723 |
Calibrated spectrographic imaging
The present application is directed to the use of photon migration analysis to provide a method of analyzing the diffuse reflectance, fluorescence, Raman or other types of spectra obtained from...
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5446538 |
Process and device for emission spectorscopy
Process for emission spectroscopy, particularly for laser emission spectropy, wherein the radiation emitted by the laser-induced plasma of the workpiece to be analyzed is decomposed by a...
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5444527 |
Imaging flow cytometer for imaging and analyzing particle components in a liquid sample
An imaging flow cytometer for capturing images and, analyzing particle components in a liquid sample containing particle components such as blood and urine, or microparticles such as organic high...
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5436718 |
Mutli-functional photometer with movable linkage for routing optical fibers
A multi-functional photometer includes a scanning mechanism having a housing (10) that bears a movable linkage (12). The linkage is coupled to an optical scanning head (18) and incorporates optical...
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5432061 |
Method and apparatus for detecting microorganisms
The present invention describes a method and apparatus for detecting microorganisms in a large number of blood culture vials using more than one microorganism detection principle for each vial. Two...
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5430541 |
High efficiency fluorescence flow cell for capillary liquid chromatography or capillary electrophoresis
A fluorescence flow cell having a capillary through which a sample fluid is moved, an optical source that directs an exposing beam of light through the sample fluid, a collector that collects...
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5424825 |
Spectral-band filtration spectrometry apparatus
The filtration means filter the exciter radiation (EX) in a first forward direction from generator means (LS) to the specimen (EC), by allowing a second spectral band (BZ) of predetermined spectral...
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5422719 |
Multi-wave-length spectrofluorometer
A multi-wavelength spectrofluorometer suitable for operation in laboratory, process control environments and in the field. The unit includes a multi-source flash tube, slits, diffraction grating...
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5422712 |
Apparatus for measuring fluorescent spectra of particles in a flow
A sample liquid flow containing particle components such as blood and urine is illuminated with light, and signals from particles are detected, and the particles are thereby analyzed. In this...
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5400137 |
Photometric means for monitoring solids and fluorescent material in waste water using a stabilized pool water sampler
Turbidity and fluorescence measurements are taken simultaneously from a waste water sample in a stabilized pool of water in order to determine both the amount of solids and the amount of...
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5399866 |
Optical system for detection of signal in fluorescent immunoassay
An imaging system responsive to focused laser light includes a focusing lens for focusing the laser light and a mirror having a reflective side, a non-reflective side, and a hole for passing a...
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5383200 |
Eye safe laser imaging system
An active night vision system capable of viewing a target over long distances utilizes laser illumination in eye-safe, invisible wavelength regions of about 1.52-1.76 μm or about 2.03 μm-2.34 μm...
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5381224 |
Scanning laser imaging system
A scanning optical imaging or mapping system for macroscopic specimens is disclosed, which allows both confocal and non-confocal imaging to be performed in reflected light, photoluminescence,...
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5379103 |
Method and apparatus for in situ detection of minute amounts of trace elements
A mobile laboratory for in situ detection of organic and heavy metal pollutants in ground water is disclosed. Pulsed laser energy is delivered via fiber optic media to create a laser spark on a...
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5377004 |
Remote optical measurement probe
A holographic probe facilitates the measurement of radiative effects such as Raman scattering or fluorescence of a remotely disposed sample. Improving upon prior-art techniques, the probe teaches a...
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5374563 |
Surface plasmon resonance device and method of determining biological, biochemical, or chemical analyte
A sensor based on the technique of surface plasmon resonance (SPR) comprises an SPR device, a source of electromagnetic radiation from which radiation can be directed onto the device, and a...
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5371016 |
Detecting biological activities in culture vials
An apparatus for detecting microorganisms in a plurality of sealable containers adapted to sustain microorganism growth includes a single light source such as a laser with a two-dimensional laser...
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5371586 |
Low aberration diffraction grating system
A light analysis system is disclosed and comprises a source of substantially collimated light to be analyzed. The source comprises a sample excited by a collimated laser light source, and further...
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5369496 |
Noninvasive method and apparatus for characterizing biological materials
Biological material is characterized by illuminating the material with a beam of light, measuring light scattered from the material and then determining the condition of the material using the...
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5363189 |
Spectroscopic analysis method and analyzing system
A plurality of elements in a sample are specified as monitoring elements. Each time at a exciting the sample, the light intensity of the line of the monitoring elements and the measured elements is...
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RE34782 |
Fluorometer
A fluorometer for measuring a particular fluorescence emanating from a specimen and operating in accordance with the following method. Producing a burst of concentrated light energy and directing...
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5352412 |
Apparatus for generating pyrolyzates of microscopic particles
An optical microscope supports a housing having a closed chamber in which a particle to be pyrolyzed is disposed and is exposable to a targeting laser beam for precisely positioning the particle...
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5338415 |
Method for detection of chemicals by reversible quenching of silicon photoluminescence
An n-type silicon (Si) wafer is galvanostatically etched in a hydrofluoric acid (HF)-containing solution while being illuminated with a 300 watt tungsten light source to form porous silicon with...
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5329353 |
High sensitive multi-wavelength spectral analyzer
A compact, high sensitive, multi-wavelength spectral analyzer capable of simultaneously obtaining a spectral distribution of extremely weak radiation such as bioluminescence, chemiluminescence,...
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5329352 |
Spectroscopically correlated light scanning microscopy
The present invention relates to a process for producing and correlating light microscope images and spectroscopic data resolved according to wavelength of a sample by scanning individual elements...
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5327225 |
Surface plasmon resonance sensor
An optical fiber surface plasmon resonance (SPR) sensor includes both a metal layer and an overlay or underlay material on its surface. Existing fiber based SPR devices are inherently incapable of...
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5322798 |
Method for carrying out surface plasmon resonance measurement and sensor for use in the method
In a method for carrying out a surface plasmon resonance (SPR) measurement a beam of electromagnetic radiation is directed through a part transparent to it onto a surface of a material layer having...
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5317378 |
Enhancing emission of excited radiation in an analytical sample subjected to exciting radiation
A spherical sample cell (FIG. 4A) bears an external inwardly specular laye defining a hollow imaging mirror 11D and an optical aperture 11E. The mirror acts as an integrator of both the exciting...
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5315122 |
Apparatus and method for fluorescent lifetime measurement
A flow cytometer measures fluorescence lifetimes by the phase shift of a reference signal and an emission from a fluorescent particle or cell in a flow chamber in order to identify the particle or...
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5313264 |
Optical biosensor system
An optical biosensor system using internal reflection versus angle of incidence determination for the detection of biomolecules, the system comprising a sensor unit (10) with at least two sensing...
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5305759 |
Examined body interior information observing apparatus by using photo-pulses controlling gains for depths
A photo-pulse from a photo-pulse generating apparatus is branched, where one branch is radiated to an examined body and the reflected light reflected within the examined body is delayed in time in...
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5306385 |
Method for generating photoluminescence emission lines from transition element doped CAF2 thin films over a Si-based substrate
A method and apparatus for producing photoluminescence emissions (68) from thin CaF 2 films grown on either silicon or silicon/aluminum substrate shows narrow emission linewidth and high emission...
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5304465 |
Enzyme assay method using surface plasmon resonance spectroscopy
Method of performing enzyme assays using the technique of surface plasmon resonance spectrometry (SPRS). An SPRS surface carries an immobilized reagent which is capable of being released by an...
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5303025 |
Emission spectrochemical quantitative analysis method and apparatus
A quantitative analysis of the constituents in a specimen and being classified by the conditions of the constituents in the specimen, using a spectroscopic analysis is made by exciting the specimen...
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5303026 |
Apparatus and method for spectroscopic analysis of scattering media
Apparatus and method for spectroscopic analysis of scattering media. Subtle differences in materials have been found to be detectable from plots of intensity as a function of wavelength of...
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5296703 |
Scanning confocal microscope using fluorescence detection
A scanning confocal microscopes scans a sample with an incident beam of ultraviolet radiation, in a raster scan pattern, causing the sample to fluoresce and emit visible radiation, a portion of...
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5293213 |
Utilization of a modulated laser beam in heterodyne interferometry
Two laser beams of different frequencies are combined to form a composite carrier beam of a frequency midway between those of the individual beams and modulated at the beat frequency between the...
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5270788 |
Apparatus for measuring polarization of bathochromically shifted fluorescence
An improved method and apparatus for measuring polarized fluorescence emissions compensates for background emissions without separating a fluorescing material from background material. The method...
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5268304 |
Method of determining the concentration of a chemical of interest in a solution
A method determines the concentration of a chemical of interest in a solution. A permeable membrane is placed in the solution and a ligand is exuded through the membrane to continually renew the...
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5260029 |
Fluorescence detection of DNA bases
To assure detection of fluorescence produced from continuously supplied fine particles such as DNA bases with accuracy and excellent efficiency, fine particles supplied from a flow cell are...
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5260764 |
Optical particle analyzing apparatus having two types of light source
An optical particle analyzing apparatus includes a flow cytometer in which laser light and lamp light having a wavelength shorter than that of the laser light are used simultaneously when particles...
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5254207 |
Method of epitaxially growing semiconductor crystal using light as a detector
Material and impurity gases are introduced into a crystal growth chamber to grow a crystal film on a GaAs substrate. A light beam emitted from a variable-wavelength light source is applied to the...
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5252834 |
Pulsed and gated multi-mode microspectrophotometry device and method
A short pulse of laser excitation and a synchronized gating time control of a fluorescence spectrograph detector are combined with a microscope, precise focusing and delivery optics, multi-mode...
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5251008 |
Fourier transform spectroscopy and spectrometer
A Fourier transform spectrometer for conducting Fourier transform spectroscopy. The spectrometer has a light source emitting light to a sample via a rapid scan interferometer. The transmittance of...
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