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8913240 Fluorescence spectrophotometer  
A fluorescence spectrophotometer according to the present invention includes: a light source 1; a sample cell 3; an excitation-side light-dispersing system 2 for dispersing a light from the light...
8908174 Apparatus, especially microscope, for the analysis of samples  
A microscope device which has a diffraction-limited resolution volume, with multiple dye molecules that can be switched between different states, at least one of which is fluorescent. The...
8908175 Flexible scatterometry metrology system and method  
A scatterometry tool including an illumination source for directing a light beam into a first optical beam shaping and positioning element at an illumination pupil plane of the tool where the light...
8895921 Inspection apparatus and replaceable door for a vacuum chamber of such an inspection apparatus and a method for operating an inspection apparatus  
An inspection apparatus is provided comprising in combination at least an optical microscope (2, 3, 4) and an ion- or electron microscope (7, 8) equipped with a source (7) for emitting a primary...
8890323 Sub-micrometer fluidic channel for measuring photon emitting entities  
A nanofluidic channel fabricated in fused silica with an approximately 500 nm square cross section was used to isolate, detect and identify individual quantum dot conjugates. The channel enables...
8878920 Method and apparatus for protection from high intensity light  
A method and apparatus where the output from a high intensity light source is controlled to produce well-exposed images/videos and to reduce automatically the intensity when an unsafe issue is...
8826519 System for replacing the water cooled laser in a microplate reader  
The present invention relates to a method and system for repairing and refurbishing a microplate reader of the Flipr type which has a water cooled argon laser light source. The old laser is removed...
8787752 Systems and methods for optically powering transducers and related transducers  
The present disclosure describes an optically powered transducer with a photovoltaic collector. An optical fiber power delivery method and system and a free space power delivery method are also...
8753869 Cartridge for biochemical analyses, system for biochemical analyses, and method of carrying out a biochemical process  
A cartridge for biochemical analysis includes a support, a structure, which is set on the support and contains wells for receiving a solution, and photodetectors on the support, in positions...
8755866 Method and apparatus for lymph node mapping  
A system and method for optical lymph node mapping. The system is useful for guiding sentinel lymph node biopsy surgeries. A contrast agent that includes a fluorescent dye is injected near the site...
8730306 3-D projection full color multimedia display  
Methods and systems are described herein which produce polarization-independent full color images suitable for rear-projection television sets and other multimedia displays. The system uses...
8715572 Method and apparatus for detection, analysis, and collection of rare cellular events  
Systems and methods for the detection, analysis, and collection of rare cellular events, wherein rare cellular events are defined by events comprising less than 5% of a total number of cells in a...
8689536 Advanced laser ignition systems for gas turbines including aircraft engines  
A laser ignition system for an internal combustion engine, and more specifically a gas turbine engine, is provided. The system comprises at least one laser light source configured to generate a...
8687055 Spectral imaging of moving objects with a stare down camera  
A spectral imaging system for collecting spectral information of a two dimensional heterogeneous objects while in motion relative to the imaging system without the use of a spectrograph, filters or...
8681247 Field flattening correction method for fluorescence imaging system  
Systems and methods for flattening the image across the entire field by correcting the image for both the fluorescence and scatter spatial variations. Images of a stable fluorescence target and a...
8658967 Optically pumping to sustain plasma  
A method for sustaining a plasma includes providing a volume of a gas; generating illumination of a first selected wavelength; and forming a first plasma species in a first region of the gas and a...
8654327 Spectrometer comprising solid body sensors and secondary electron multipliers  
The invention relates to a spectrometer for analyzing the optical emission of a sample by means of pulsed excitation of an optical spectral emission, having an excitation source, a gap arrangement,...
8643838 Emission spectrophotometer  
An emission spectrophotometer capable of inhibiting non-uniformity of spectral intensities of component elements is provided. The emission spectrophotometer generates pulse light emission by...
8625863 Superresolution optical fluctuation imaging (SOFI)  
Statistical analysis techniques based on auto- and cross-correlations/cumulants, of image stacks of fluctuating objects are used to improve resolution beyond the classical diffraction limit and to...
8624200 Optical detection system  
An optical detection system includes a sample carrier receiving region that receives a sample carrier carrying a sample. The system further includes a source that emits an excitation signal having...
8619260 Multi-grating biosensor for label-independent optical readers  
A multi-grating resonant waveguide (RWG) biosensor for an optical reader system having a spatial resolution limit is disclosed. The multi-grating RWG biosensor includes one or more signal-grating...
8611535 Characterization of an entangled photon system  
A quantum key distribution system comprises a source of entangled photon pairs and two single-photon detectors. The source is coupled to each of the single-photon detectors by optical fiber....
8599382 Automated in situ contaminant detection system  
The present invention provides methods and apparatuses for in situ chemical analysis of liquid sample for the collection, identification, and measurement of chemical moieties, such as, biotoxins,...
8599376 Optical microscopy with phototransformable optical labels  
An apparatus includes a position-sensitive detector to detect intensities of radiation as a function of position on the detector, and an optical system, characterized by a diffraction-limited...
8582098 Single photon spectrometer  
A fiberized single photon sensitive spectrometer based on a 32-channel PMT sensor is highly sensitive with broad detection dynamic range. The spectrometer enables accurate and high speed detection,...
8559021 Three-dimensionally localizing light emitting molecules of unknown orientation and unknown Z-position  
To the end of three-dimensionally localizing light emitting marker entities of unknown orientation and unknown position in a sample, the light emitted by each single marker entity is imaged in at...
8553225 Bandwidth tunable spectroscopic device  
An electromagnetic radiation detection device is described which includes a tunable dispersive optical element configured to receive electromagnetic radiation and to change the dispersion of the...
8551786 Systems and methods for enhancing fluorescent detection of target molecules in a test sample  
Systems and methods for enhancing fluorescent detection of target molecules in a test sample are for use with an irradiating device. First fluorophores are provided for absorption of EMF radiation,...
8541760 Method for calibrating a deflection unit in a TIRF microscope, TIRF microscope, and method for operating the same  
The invention relates to a method for calibrating a deflection unit in a TIRF microscope, by means of which an angle of incidence of excitation light onto a specimen is adjusted, wherein a setting...
8526002 Two-dimensional fourier transform spectrometer  
The present invention relates to a system and methods for acquiring two-dimensional Fourier transform (2D FT) spectra. Overlap of a collinear pulse pair and probe induce a molecular response which...
8525987 Method for operating an optical filter in multiple modes  
A method for operating an optical filter in multiple modes. In one embodiment, an optical filter may be operated in a sensitivity mode to thereby generate a white light image representative of a...
8520203 Method and device for characterizing microscopic elements  
A method and device is provided for characterizing microscopic elements. A source signal may be chopped by means of microsystems of opto-electromechanical elements (MOEMS), which gives rise to...
8507282 Method for measuring physiologically active substance of biological origin, program for implementing the same, and apparatus for measuring physiologically active substance of biological origin  
When assessing the start time of the limulus reaction between biogenous biologically active substances and LAL and using the reaction start time to determine the concentration of the biogenous...
8501480 High throughput screening of fatty acid composition  
A method of accumulating a quantity of seeds having a desired fatty acid characteristic is provided. The method includes removing a sample from each seed in a population of seeds while maintaining...
8500632 Endoscope and endoscope apparatus  
An endoscope includes an elongated insertion portion having a distal end portion provided with an illumination window and an observation window. A single solid-state image sensing device whose...
8502972 Clusters of microresonators for cavity mode optical sensing  
A method for sensing a target object using optical mode excitations in microresonators, comprises: preparing at least one cluster including at least two microresonators; obtaining some first...
8496577 Endoscope apparatus, method, and computer readable medium  
An endoscope apparatus comprising an irradiating section that switches over time between irradiating a target with light in a first wavelength region and light in a second wavelength region; a...
8487275 Method and a device for measuring fluorescence lifetime  
The invention refers to a method for measuring fluorescence lifetime. An excitation light radiation (12a), periodically modulated in a first frequency, is directed to a fluorescent material (20)....
8482734 Centrifugal device  
A device consisting of a rotatable substrate (10) with at least one cavity (14) or channel/chamber structures is described. Fluids may be provided into the at least one cavity (14) and on rotation...
8482730 Signal noise reduction for imaging in biological analysis  
A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset...
8480856 Fluorometric method for monitoring surface additives in a papermaking process  
An apparatus for and method of monitoring and optionally controlling the addition of one or more surface additives to a papermaking process via fluorometric means is disclosed.
8467055 Optical measuring device  
An optical measuring device includes: a light applying section configured to apply laser light to a sample flowing in a channel; and a fluorescence detecting section configured to detect...
8467996 Spectral analysis operating system  
Collecting and analyzing spectral data can be challenging when multiple analysis instruments need to be integrated and monitored by a quality control agent within a laboratory, industrial plant,...
8462336 Optical microscopy with phototransformable optical labels  
An apparatus includes a position-sensitive detector to detect intensities of radiation as a function of position on the detector, and an optical system, characterized by a diffraction-limited...
8462337 Spectrometer, spectrometry, and spectrometry program  
A spectroscopic measurement apparatus 1A comprises an integrating sphere 20 in which a sample S is located, a spectroscopic analyzer 30 dispersing the light to be measured from the sample S and...
8451446 Differential polarization measuring extension unit for a laser-scanning microscope  
The invention relates to a differential polarizing laser-scanning microscope (DP LSM) for determining differential polarization quantities of a material, comprising a laser light source (L) for...
8441633 Multiple-photon excitation light sheet illumination microscope  
An apparatus for and method of performing multi-photon light sheet microscopy (MP-LISH), combining multi-photon excited fluorescence with the orthogonal illumination of light sheet microscopy are...
8404488 Method for on-site drug detection in illicit drug samples  
The invention is provided for detection of Heroin and Morphine in illicit drug samples, also for their differentiation. A liquid sample from a street sample is prepared and divided into two equal...
8405827 Time-resolved spectroscopy system and methods for multiple-species analysis in fluorescence and cavity-ringdown applications  
A time-resolved spectroscopy system employing a time-division multiplexing optical device with no dispersive optical elements to perform lifetime and concentration measurements in multi-species...
8405828 Spatial positioning of spectrally labeled beads  
Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with...