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8467055 |
Optical measuring device
An optical measuring device includes: a light applying section configured to apply laser light to a sample flowing in a channel; and a fluorescence detecting section configured to detect...
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8467996 |
Spectral analysis operating system
Collecting and analyzing spectral data can be challenging when multiple analysis instruments need to be integrated and monitored by a quality control agent within a laboratory, industrial plant,...
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8462336 |
Optical microscopy with phototransformable optical labels
An apparatus includes a position-sensitive detector to detect intensities of radiation as a function of position on the detector, and an optical system, characterized by a diffraction-limited...
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8462337 |
Spectrometer, spectrometry, and spectrometry program
A spectroscopic measurement apparatus 1A comprises an integrating sphere 20 in which a sample S is located, a spectroscopic analyzer 30 dispersing the light to be measured from the sample S and...
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8451446 |
Differential polarization measuring extension unit for a laser-scanning microscope
The invention relates to a differential polarizing laser-scanning microscope (DP LSM) for determining differential polarization quantities of a material, comprising a laser light source (L) for...
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8441633 |
Multiple-photon excitation light sheet illumination microscope
An apparatus for and method of performing multi-photon light sheet microscopy (MP-LISH), combining multi-photon excited fluorescence with the orthogonal illumination of light sheet microscopy are...
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8404488 |
Method for on-site drug detection in illicit drug samples
The invention is provided for detection of Heroin and Morphine in illicit drug samples, also for their differentiation. A liquid sample from a street sample is prepared and divided into two equal...
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8405827 |
Time-resolved spectroscopy system and methods for multiple-species analysis in fluorescence and cavity-ringdown applications
A time-resolved spectroscopy system employing a time-division multiplexing optical device with no dispersive optical elements to perform lifetime and concentration measurements in multi-species...
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8405828 |
Spatial positioning of spectrally labeled beads
Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with...
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8395770 |
Spectroscopic chemical analysis methods and apparatus
Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor...
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8390813 |
Apparatus and method for monitoring of gas having stable isotopes
Gas having stable isotopes is monitored continuously by using a system that sends a modulated laser beam to the gas and collects and transmits the light not absorbed by the gas to a detector. Gas...
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RE44007 |
Low-noise spectroscopic ellipsometer
A spectroscopic ellipsometer comprising a light source (1) emitting a light beam, a polarizer (2) placed on the path of the light beam emitted by the light source, a sample support (9) receiving...
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8379201 |
Method and devices for imaging a sample
The invention relates to methods and devices for imaging a sample, in particular to methods and devices for imaging electrophoretic gels which have been used to separate biological molecules such...
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8368884 |
Spectroscopic determination of analyte concentration
A spectroscopic apparatus for determining a concentration and/or spatial gradient of an analyte of a bodily fluid that provides determination of a position of a capillary vessel within a biological...
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8345228 |
Measuring device and method for determining optical characteristic variables for verifying photochemical and electrochemical degradative reactions
A measuring device for quantitative determination of optical characteristic values for detecting photo- and/or electrochemical decomposition reactions taking place on surfaces of photocatalytically...
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8339599 |
Measuring arrangement for an optical spectrometer
The invention relates to a measuring arrangement for an optical spectrometer, in particular a photon density wave spectrometer, having a measuring chamber, which can be loaded with a sample to be...
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8326405 |
Imaging of macular pigment distributions
Macular pigments are measured by spectrally selective lipofuscin detection. Light from a light source that emits light at a selected range of wavelengths that overlap the absorption band of macular...
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8313799 |
Adhesive detection methods
Adhesive compositions useful for bonding fluorescent material-containing cellulosic substrates such as envelopes may be formulated using an adhesive polymer such as an emulsion of polyvinyl acetate...
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8305573 |
Method of monitoring and controlling of mixing processes
A method for determining the degree of mixing between components in a mixing process, the method including the steps of: a) mixing at least two components and at least two luminescent materials to...
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8289503 |
System and method for classifying a disease state using representative data sets
System and method for determining a disease state of a sample. A sample is positioned in a field of view and a first spectroscopic data set is obtained. The positional information is stored and the...
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8274650 |
Signal noise reduction for imaging in biological analysis
A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset...
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8269964 |
Photon measurement method and apparatus
A system and method for measuring photons utilizing a low-power light source modulated with a code sequence to interrogate a sample of interest. Preferably a portion of the scattered light from the...
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8269965 |
Method of analysis of samples by determination of a function of specific brightness
A method for characterizing samples having units, by monitoring fluctuating intensities of radiation emitted, scattered and/or reflected by said units in at least one measurement volume, the...
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8263001 |
Integrated bio-chip, method of fabricating the integrated bio-chip, and apparatus for detecting bio-material
An integrated bio-chip includes a substrate and one or more excitation light absorbing waveguides disposed in the substrate. The substrate includes one or more reaction regions on which samples are...
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8264680 |
Biochip reader and electrophoresis system
A biochip reader wherein spectroscopic information of a sample under analysis is arranged in spaces between images of the sample arranged on a biochip. The reader comprises a confocal microscope...
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8247551 |
Lead sensor and methods of use
A fluorophore that forms a complex with Pb ions is disclosed. The fluorophore/lead complex fluoresces with an intensity greater than complexes formed by the fluorophore with other metals. The...
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8237923 |
Bio-sample image pickup device
A bio-sample image pickup device includes a light source module, a carrier, an image pickup unit, a first filter set, and a second filter set. The carrier carries the light source module and the...
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8236245 |
Micro-pixelated fluid-assay precursor structure
A pixel-by-pixel, digitally-addressable, pixelated, precursor, fluid-assay, active-matrix micro-structure including plural pixels formed preferably on a glass or plastic substrate, wherein each...
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8236244 |
Micro-pixelated fluid-assay structure with on-board addressable, pixel-specific functionalization
A digitally-addressable, pixelated, DNA fluid-assay, active-matrix micro-structure formed, utilizing low-temperature TFT and Si technology, on a substrate preferably made of glass or plastic, and...
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8222623 |
Generation of quantum-correlated and/or polarization entangled photon pairs with unequal wavelengths
The invention provides an apparatus and method for generating quantum-correlated and/or polarization-entangled photon pairs with unequal wavelengths. The photon pairs generated collinearly with...
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8218141 |
Universal multidetection system for microplates
An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first...
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8213005 |
Method for discriminating between benign and malignant prostate tumors
The method for discriminating between benign and malignant prostate tumors relates to analyzing samples of blood, urine and tissue by fluorescence spectroscopy in order to detect the presence of...
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8194247 |
SHG quantification of matrix-related tissue dynamic and disease
A microscope for optical imaging of high optical scattering coefficient biological tissue, comprising an optical excitation source for irradiating a scan area of the sample and generating optical...
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8187541 |
Apparatus for detecting target molecules and related methods
An apparatus for analysis of a sample and in particular of a biological sample. The apparatus contains a microfluidic chip with dies, adapted to be selectively activated or deactivated by presence...
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8179526 |
Spectroscopic apparatus with dispersive device for collecting sample data in synchronism with relative movement of a focus
In a Raman spectroscopy apparatus, exciting light is focussed on a sample (26) as a line focus 38. Spectra from points in the line focus are dispersed in rows 46 on a CCD detector 34, having a...
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8173982 |
Non-degenerate polarization-entangled photon pair generation device and non-degenerate polarization-entangled photon pair generation method
A non-degenerate polarization-entangled photon pair generation device (1) that efficiently and easily generates non-degenerate polarization-entangled photon pairs includes: a quantum-entangled...
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8174692 |
High spatial resolution imaging of a structure of interest in a specimen
In high spatial resolution imaging, a structure in a specimen is marked with a substance which, in a first electronic state, is excited by light of one wavelength to emit fluorescent light, which...
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8163241 |
Optical probe
An optical probe for detecting luminescence emitted by a sample is disclosed. The optical probe includes a parabolic optical waveguide and an outer housing having a detachable component configured...
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8149413 |
Surface plasmon resonance sensing device
A surface plasmon resonance sensing device that is portable, and having the fiber sensing unit whose resonant wavelength being within the transmission range of a single-mode fiber or a multi-mode...
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8149399 |
Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems...
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8144323 |
Apparatus, method and computer-readable storage medium for determining the ring-down time in a spectrometer system
A system is provided that includes a cavity ring-down spectrometer and a processor. The spectrometer is configured to pass, through a cavity resonator, a modulated, continuous-wave electromagnetic...
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8139211 |
Fluorescence polarization imaging device and method
The present invention is directed to a novel multi-spectral exogenous fluorescence polarization imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a...
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8130383 |
Optical signal analysis apparatus and optical signal analysis method
An optical signal analysis apparatus includes a photodetector and an analyzer. The photodetector is to detect light emitted from measurement points in a sample. The analyzer is to analyze a...
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8120765 |
Observation device
An observation device 1 comprises a light source unit 10, a biaxial scanning system 20, a wavefront modulation unit 30, an optical branching unit 40, a light detection unit 50, a wavefront...
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8115150 |
Optical substrate for reduced background fluorescence
A new optical substrate design allows a target to be illuminated with minimal illumination of undesired surfaces within the image collection ray path. The non rectangular substrate provide...
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8103331 |
Systems and methods for in-vivo optical imaging and measurement
Disclosed are methods and systems for: (i) sequentially illuminating a specimen with different spatial distributions of light, wherein each illumination causes an object embedded in the specimen to...
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8094294 |
Multipoint method for identifying hazardous agents
The invention relates to apparatus and methods for assessing occurrence of a hazardous agent in a sample by performing multipoint spectral analysis of the sample. Methods of employing Raman...
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8094302 |
Spectrophotometer
Disclosed herein is a spectrophotometer. The spectrophotometer includes a CPU having a signal prediction part and a comparison/calculation part. The signal prediction part predicts the strength of...
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8084755 |
Time-domain method and apparatus for determining the depth and concentration of a fluorophore in a turbid medium
Methods and apparatuses for determining the depth and concentration of fluorophores in a turbid medium are disclosed. The method advantageously provides for a rapid estimation of the depth of the...
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8078267 |
Imaging of macular pigment distributions
Macular pigments are measured by spectrally selective lipofuscin detection. Light from a light source that emits light at a selected range of wavelengths that overlap the absorption band of macular...
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