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7381423 |
Use of nanodispersions in cosmetic end formulations
A description is given of the use of a nanodispersion, which comprises
(a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component,
in cosmetic end formulation, which...
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7234290 |
Process for producing aspheric seamless capsule and apparatus therefor
In manufacturing an aspherical seamless capsule comprises, firstly, a seamless capsule C 1 having a filler encapsulated with a shell membrane is provided, then it is dried in a dryer 12 until a...
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7158283 |
Method of manufacturing display and electronic apparatus
A method of manufacturing a display that includes a first substrate having a pixel electrode, a second substrate having a common electrode, and a microcapsule interposed between the first and...
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7153754 |
Methods for forming porous insulators from “void” creating materials and structures and semiconductor devices including same
Methods for forming porous insulative materials for use in forming dielectric structures of semiconductor devices are disclosed. Each insulative material may include a first, substantially...
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7105181 |
Microparticles
A process for producing parenterally administrable microparticles, in which an at least 20% by weight aqueous solution of purified amylopectin-based starch of reduced molecular weight is prepared,...
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7074883 |
Acid end group poly(D,L-lactide-co-glycolide) copolymers with high glycolide content
Copolymers of lactide and glycolide with high glycolide content. The average glycolate block length is less then about 3, which allows the copolymer to be soluble in slightly polar solvents such as...
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7041320 |
High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence
Methods and compositions to induce opioid drug independence in opioid drug dependent individuals comprising administering opioid agonists and/or antagonists encapsulated in biodegradable polymer...
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7041241 |
Use of biodegradable microspheres that release an anticancer agent for treating gliobastoma
The invention relates to the use of biodegradable microspheres that release a radiosensitizing anticancer agent for producing a medicament to be used simultaneously with, separately from or spread...
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7033609 |
Microparticle preparation
A parenterally administrable, biodegradable microparticle preparation containing a biologically active substance which, during the first 24 hours after injection, exhibits a release of the active...
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7025988 |
Liposomes
Liposomes containing lipophilic active ingredient are produced by dehydrating a mixture of liposomes, lipophilic active ingredient and sugar, usually followed by a rehydration step to form...
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7019106 |
Lactic acid polymer and process for producing the same
A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular...
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7011776 |
Method and apparatus for preparing microspheres
An improved method for the preparation of a microsphere from an emulsion wherein an organic phase containing an organic solvent having a boiling point lower than that of water and a...
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6979467 |
Microcapsules IV
A microcapsule having a mean diameter of from about 0.1 to about 5 mm, a membrane and a matrix containing at least one active principle wherein the microcapsule is the product of the process...
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6979461 |
Method for producing liposome preparation
An object of the present invention is to provide a method for producing a liposome preparation having excellent rapid action and excellent redispersion into aqueous medium. The present invention...
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6932984 |
Method of microencapsulation
A method for microencapsulation of substances is provided. The substance(s) is/are dissolved or dispersed in an organic solvent of the kind that is partially miscible in water media. This organic...
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6926905 |
Liposomak compositions and methods of preparation
Long-term local anesthesia is provided by administering to a subject in need thereof a liposomal anesthetic formulation prepared by the dehydration-rehydration method. In this method, lyophilized...
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6884372 |
Method for preparing microparticles using liquid-liquid extraction
Method and apparatus for preparing microparticles using liquid-liquid extraction. A first phase and a second phase are combined to form an emulsion. A portion of the second phase is separated from...
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6861016 |
Apparatus and method for preparing microparticles
Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static...
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6838089 |
Antigen delivery system and method of production
The present invention concerns polymer particle vaccine delivery systems in which a water insoluble protein antigen, e.g. a lipidated HpaA protein, is incorporated with particles comprising a...
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6824791 |
Methods for micronization of hydrophobic drugs
The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is...
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6818296 |
Microcapsules
A microcapsule having a mean diameter of from about 0.1 to about 5 mm, a membrane and a matrix containing at least one active principle wherein the microcapsule is the product of the process...
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6815432 |
Methods for encapsulating plasmids in lipid bilayers
Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are described. The particles can be formed using either detergent dialysis methods or methods which utilize...
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6743438 |
Colored contact lenses and method of making same
Optical lenses and methods of preparing the same, in which an active material encapsulated in resin capsules is impregnated in said lens, adjacent an optical surface thereof. The active material...
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6719932 |
Particles and a process for preparing the same
Disclosed are a plurality of particles having a narrow particle size distribution, a processes for forming the same, and films containing the same. The plurality of particles, includes one or more...
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6706288 |
Microparticles
A process for producing parenterally administrable microparticles, in which an at least 20% by weight aqueous solution of purified amylopectin-based starch of reduced molecular weight is prepared,...
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6682758 |
Water-insoluble drug delivery system
The present invention provides a drug delivery system comprising a water-insoluble drug, a water-miscible organic solvent for the water-insoluble drug, a surfactant, and water, as well as a process...
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6616949 |
Process for producing microparticles
A process for producing microparticles containing biologically active substance, in which process an aqueous solution of the said substance is prepared, this solution is mixed with an aqueous...
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6605298 |
Pharmaceutical compositions and their use
The invention provides a composition for delivering at least one biologically active compound to a living organism, said composition comprising at least one micelle-forming membrane lipid
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6592990 |
In situ microencapsulated adhesive
A novel adhesive formed in situ in a microcapsule and method for forming such a pressure sensitive or flowable adhesive in situ in a microcapsule is disclosed. The method for forming the novel...
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6592844 |
Preparation of protein microspheres, films and coatings
A process is described for preparing microspheres, films and coatings from protein or modified protein in which the protein product is stabilized by carrying out the preparation in the presence of...
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6565777 |
Encapsulation of bioactive agents
Bioactive agent is encapsulated in a polymer microparticle in a (water-in-oil)-in-water emulsion-based method, and using a solvent that comprises ethyl acetate. Also described are microparticles...
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6537583 |
Method for preparing capsules consisting of a liquid active material core enclosed in a mineral coating
The invention concerns a method for preparing mineral capsules consisting of aqueous liquid core enclosed in mineral coating, said method consisting in: 1) emulsifying an aqueous fluid in a phase...
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6534094 |
Manufacturing process of microcapsules for sustained release of water soluble peptides
A process for the manufacturing of microcapsules for sustained release of water soluble peptides, with adjustable release periods of between 1 to 18 weeks. The microcapsule wall are made of a...
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6534092 |
Method for preparing microparticles having a selected polymer molecular weight
A method for preparing microparticles having a selected polymer molecular weight. The hold time and temperature of a solution containing a nucleophilic compound and a polymer having a starting...
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6528092 |
Synthetic membranes and micelle-like structures comprising lipo-glycoprotein membranes
Synthetic membranes, micelles and vesicles are formed in response to the spontaneous orientation of hydrophobic and hydrophilic groups in aqueous media. The oligosaccharide moieties of glycoprotein...
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6514523 |
Carrier particles for drug delivery and process for preparation
This invention relates to a carrier particle having a diameter of from 5 to 20 nm which contains an HDL apolipoprotein, an amphipathic lipid such as a phospholipid, and a drug which is either a...
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6500461 |
Particulate formulations
This invention provides vehicles capable of delivering high concentrations of poorly hydrophilic/poorly lipophilic compounds to animals, by combining compounds having biocompatible hydrophobic...
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6471995 |
Apparatus and method for preparing microparticles using liquid-liquid extraction
Method and apparatus for preparing microparticles using liquid-liquid extraction. A first phase and a second phase are combined to form an emulsion. A portion of the second phase is separated from...
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6461545 |
Method of solubilizing and encapsulating itraconazole
Methods for preparing microspheres containing imidazole derivatives are provided. Also provided is the use of imidazole derivatives containing microspheres for treating fungal infections. Oral...
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6451338 |
Liposomes containing particulate materials
A method is provided for the formation of liposomes of 0.1 μm to 50 μm in diameter having unilamella or multilamella structure and containing water insoluble or undissolved particulate materials...
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6447800 |
Method of loading preformed liposomes using ethanol
This invention provides methods of loading preformed liposomes by transmembrane permeation induced by alcohols. Solutes loaded into liposomes by this ethanol mediated process include both small...
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6440493 |
Emulsion-based processes for making microparticles
Processes for making microparticles, preferably containing an active agent, are provided. In a preferred embodiment, the process involves preparing (1) a dispersed phase containing an agent in a...
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6428815 |
Method of producing sub-micron particles of biologically active agents and uses thereof
Submicron particles of a biologically active agent are prepared by atomizing using multifluid atomization a dispersed system comprising at least one biologically active agent and at least one...
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6391452 |
Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
The present invention relates to pharmaceutical compositions for delivery of drugs intended to reside in the nose, compositions for nasal administration of drugs, e.g., antiviral agents, and...
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6372260 |
Incorporation of active substances in carrier matrixes
A process for the incorporation of an active substance in a carrier system by forming an emulsion of the components and precipitating the system by the use of fluid gas technique.
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6355267 |
Liposome preparation and material encapsulation method
The present invention relates to a method of producing liposomes useful for encapsulating and delivering a wide variety of biologically active materials. The invention provides liposomes and a...
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6352716 |
Steroidal liposomes
Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such...
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6348214 |
Materials and methods for making improved liposome compositions
Provided are methods for preparing improved biologically active liposome products comprising a biologically active amphipathic compound in association with a liposome. Methods for producing the...
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6331314 |
Method and device for producing a parenteral medicament
In the procedure for the production of a formulation of parenterally administrable pharmaceutical preparations, a liposome dispersion is used as a carrier for a pharmaceutical active compound. For...
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6241999 |
Method for producing liposomes with increased percent of compound encapsulated
The efficiency of encapsulating a drug into a liposomal formulation is increased by use of a lipid having a carbon chain containing from about 13 to about 28 carbons during preparation of the...
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