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7312448 |
Method and apparatus for quantitative three-dimensional reconstruction in scanning electron microscopy
A method and an apparatus are for three-dimensional tomographic image generation in a scanning electron microscope system. At least two longitudinal marks are provided on the top surface of the...
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7306942 |
Endospore detector
The invention herein provides for the detection of certain calcium containing endospores, and particularly pertains to the detection of bacillus anthracis by first chelating calcium ions of said...
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7304315 |
Three dimensional analyzing device
A three-dimensional analyzing device includes a first beam source for generating a first beam, a second beam source for generating a second beam, an optical system for spatially overlapping the...
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7301626 |
Laser-scanning examination apparatus
The invention reduces the loss of fluorescence intensity obtained from a specimen to acquire clear fluorescence images when irradiating the specimen with ultrashort-pulse laser light produced by a...
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7294826 |
Bio-sensing apparatus
A multi-channel sensor is provided with sensor sections, each of the sensor sections reflecting or transmitting light, whose physical characteristics vary for different kinds of samples. Each of...
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7267457 |
Method for detecting forensic evidence
A method for detecting forensic evidence. The method includes use of a forensic light that may utilize a variety of semiconductor light sources to produce light that contrasts forensic evidence...
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7247443 |
Sensor constructs and detection methods
Sensor constructs for detecting the presence of an analyte in a sample comprise a molecular scaffold, a pair of labels which interact via Förster resonance energy transfer, and at least one...
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7232687 |
Multiple sorter monitor and control subsystem for flow cytometer
An optical illumination and monitoring subsystem controls the operation of a flow cytometer having a carrier fluid that flows along a channel coupled to a droplet generator, which controls a point...
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RE39672 |
Method and devices for laser induced fluorescence attenuation spectroscopy
The Laser Induced Fluorescence Attenuation Spectroscopy (LIFAS) method and apparatus preferably include a source adapted to emit radiation that is directed at a sample volume in a sample to produce...
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7223232 |
Endoscope probe system having confocal optical systems
An endoscope probe system includes an endoscope probe to be inserted into a body cavity to observe tissue of a living body. The endoscope probe system further includes a laser source that emits...
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7217937 |
Automatic identification of suspended particles
The present invention relates to the automatic analysis and identification of different species of particles in a liquid sample using both fluorescent tagging and magnification techniques. A light...
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7199378 |
Method for measuring and analyzing bioluminescence and device for measuring and analyzing bioluminescence
A method for measuring and analyzing bioluminescence, including the steps of receiving in real-time a luminescence measurement result group from a creature sample group, displaying and maintaining...
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7148492 |
System, method, and product for providing a wavelength tunable excitation beam
A method for scanning a probe array is described. The method comprises tuning an excitation light to a plurality of wavelengths each within an excitation range of a fluorescent label associated...
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7138280 |
Masking of the background fluorescence and luminescence in the optical analysis of biomedical assays
In a process for the quantitative optical analysis of biological cells labelled with a fluorescent dye, the sensitivity of analytical detection can be considerably improved if a masking dye, which...
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7122799 |
LED or laser enabled real-time PCR system and spectrophotometer
A system for conducting a polymerase chain reaction (PCR) assay upon a collection of samples is disclosed. The PCR assay is performed by absorption detection. The system includes a multi-well plate...
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7109495 |
Fluorometer with low heat-generating light source
This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present...
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7092087 |
Laser-induced breakdown spectroscopy for specimen analysis
The present invention is directed to an apparatus, a system and a method for detecting the presence or absence of trace elements in a biological sample using Laser-Induced Breakdown Spectroscopy....
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7060992 |
System and method for bioaerosol discrimination by time-resolved fluorescence
The systems and methods of the invention utilize time-resolved techniques to deconvolve a measured response to characterize the nature of particles. The measured response is deconvolved into a...
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7057185 |
Maximum sensitivity optical scanning system
A maximum sensitivity optical scanning system is disclosed. It finds use in a variety of applications, including the reading of biopolymeric arrays. It operates by scanning sample at a setting...
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7016043 |
Quality evaluation method and apparatus for non-bran rice
A quality evaluation method and apparatus for non-bran rice evaluate quality or taste of non-bran rice by identifying proportions of a hull layer, an aleurone layer, an endosperm layer, which...
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7005653 |
Near-field intra-cellular apertureless tomographic imaging
A method and apparatus for near-field intra-cellular apertureless tomographic imaging uses sub-wavelength nano-particle in a cell which generates tomographic projections. A detector detects and...
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7003143 |
Tomographic microscope for high resolution imaging and method of analyzing specimens
Tomographic methods and device for obtaining images of microscopic specimens such as Pap smears.
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6990369 |
Probe using diffuse-reflectance spectroscopy
The invention provides a device and method for monitoring inflammation of the epithelium. The device consists of a head region, a handle region and an optical bundle. At least two of the optical...
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6985224 |
Light emitting diode (LED) array for excitation emission matrix (EEM) fluorescence spectroscopy
This invention discloses an Excitation Emission Matrix (EEM) fluorescence spectrometer system that uses an LED array to cause excitation emission matrix fluorescence that is imaged onto a...
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6979828 |
Method and apparatus for immediately determining microorganism
A microorganism double-stained with appropriate fluorescent reagents is dropped onto a light permeable plate or passed through a micro-tube and irradiated with excitation light. As a result, the...
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6956203 |
Scanning system with calibrated detection and method
A self-calibrating scanning system and method are used in the analysis of biomolecules on a microarray. The self-calibrating scanning system comprises an excitation light source, an optical...
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6954270 |
Method for detecting forensic evidence
A semiconductor forensic light is disclosed. The forensic light may use a variety of semiconductor light sources to produce light that contrasts forensic evidence against its background for...
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6949754 |
Apparatus for measuring in particular luminescent and/or fluorescent radiation
An apparatus for selected measurement of, in particular, luminescent and/or fluorescent radiation has a plurality of measurement light paths (M 1 , M 2 , M 3 ), which each have their own measuring...
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6936827 |
Detecting device for fluorescent-labeled material
A fluorochrome-marked sample is excited with the proper wattage and wavelength of light using an exciter or bandpass filter and beamsplitting mirror device. This causes the sample to emit light of...
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6913200 |
Scanning parameterization for biopolymeric array scanner
Methods for programming an array scanner to scan a plurality of biopolymer arrays are provided. In the subject methods, individual scanning parameters for at least two different arrays of the...
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6878949 |
Gel imaging and excision
A robot for imaging and excision of two-dimensional fluorescent gels. An array detector is mounted in the roof of the robot to image down onto a gel dish placed on a light table. Fluorescence is...
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6878948 |
Method and arrangement for locating specimen regions
The invention discloses a method for locating specimen regions of interest in a stimulatable microscopic specimen ( 13 ) that comprises the steps of: introducing into a specimen ( 13 ) of at least...
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6867051 |
Point of care diagnostic systems
Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and...
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6852986 |
Fluorometer with low heat-generating light source
This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present...
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6835946 |
Image reading method and apparatus
An image reading apparatus is adapted for irradiating an image carrier including a labeling substance contained in two-dimensionally distributed spots with a stimulating ray and photoelectrically...
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6834240 |
Software for the display of chromatographic separation data
Techniques for displaying chromatographic data using a graphical user interface are provided. Chromatographic separation data that is a series of measurements for a sample at a scanning location...
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6831994 |
System and apparatus for sequential processing of analytes
An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte...
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6831279 |
Laser diode-excited biological particle detection system
Apparatus is provided for detection of viable and potentially hazardous biological particles in a population which may be dispersed in fluid flow. The particles are characterized as biological and...
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6826422 |
Spectral volume microprobe arrays
Methods and apparatus are provided for determining a characteristic of a sample of a material by the interaction of electromagnetic radiation with the sample. The apparatus includes an optical...
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6819411 |
Optical apparatus
Various optical apparatus provide a source of parallel light ( 7, 75 ). The parallel light ( 7, 75 ) is generally achieved by directing an incident beam at the apex of a prism ( 1, 22, 24, 26, 28...
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6818903 |
Method and apparatus for identifying spectral artifacts
The invention provides an apparatus and methods for determining whether spectral data obtained from a region of a tissue sample are affected by an artifact. Artifacts include, for example, lighting...
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6790671 |
Optically characterizing polymers
The invention relates to new systems, methods and products for analyzing polymers and in particular new systems, methods and products useful for obtaining sequence information from polymers. The...
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6693287 |
Laser imaging apparatus using biomedical markers that bind to cancer cells
A method for collecting data for use in image reconstruction of a tissue being scanned containing cancer cells comprises the steps of providing a source of laser beam; providing a biochemical...
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6686582 |
Optical array system and reader for microtiter plates
An optical system made up of lens arrays and normal lenses is particularly suitable for use as a massive parallel reader (approximately 10 2 channels) for microtiter plates and the like in...
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6683314 |
Fluorescence detection instrument with reflective transfer legs for color decimation
An optical instrument using a plurality of lasers of different colors with parallel, closely spaced beams to stimulate scattering and fluorescence from fluorescent biological particulate matter,...
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6674527 |
Ratiometric background correction for fluorescence polarization assays
A method in which a multiplicative ratio approach is used to remove the effects of the unwanted background fluorescence when making fluoroescence polarization (FP) measurements rather than the...
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6664550 |
Apparatus to collect, classify, concentrate, and characterize gas-borne particles
An aerosol lab-on-a-chip (ALOC) integrates one or more of a variety of particle collection, classification, concentration (enrichment), an characterization processes onto a single substrate or...
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6662039 |
Optical probing of neuronal connections with fluorescent indicators
This invention provides methods of identifying a connection between a first neuron and a second neuron or plurality of neurons in a neural tissue slice with a fluorescent indicator. This invention...
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6653146 |
Bio-burden visualization system
A method of visualizing biological material on medical instruments is disclosed which consists of the steps of selecting a dye material capable of creating fluorescence or phosphorescence when...
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6646272 |
Fiber optic coupling device for detecting luminescent samples
A fiber optic coupling plate ( 24 ) has a sample viewing face for receiving light from a sample ( 12 ), an output window ( 18 ) for conveying sample originating (emitted) light to an imaging...
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