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7310147 |
Robotic apparatus for picking of cells and other applications with integrated spectroscopic capability
A robotic apparatus of the kind having a sample manipulation head with associated positioning system mounted above the main bed of the apparatus, as used for picking of cells, in particular animal...
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7309867 |
Methods and apparatus for characterization of tissue samples
The invention provides methods for determining the probability that a given region of a tissue sample contains tissue of a given category, such as CIN 1 (cervical intraepithelial neoplasia, grade...
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7307730 |
Apparatus and method for measuring temperature dependent properties of liquid
The present invention relates generally to an improved method and apparatus for measurement of properties of a sample as a function of temperature. The method and apparatus are based on formation...
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7307718 |
Determining an analyte by multiple measurements through a cuvette
A method for measuring the presence or concentration of an analyte in a sample by spectrophotometry: providing an open top cuvette having a sample with an analyte to be measured; providing a light...
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7307713 |
Apparatus and method for inspection of a wafer
The invention concerns an apparatus and a method for inspection of a wafer. The apparatus encompasses at least one stroboscopic incident-light illumination device for emitting a pulsed...
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7307261 |
Fluorescence detecting apparatus
A fluorescence detecting apparatus includes: a light source for illuminating the surface of detection of a sample with excitation light; a CCD area image sensor for detecting fluorescence emitted...
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7304733 |
Method and device for conducting the spectral differentiating, imaging measurement of fluorescent light
A method and a device for image producing measurement of fluorescent light, according to which a sample containing fluorophores of different species is irradiated with excitation light of at least...
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7304314 |
Quantum cross-ambiguity function generator
A cross-ambiguity function generator (“CAF”) uses properties of quantum mechanics for computation purposes. The CAF has advantages over standard analog or digital CAF function generators, such...
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7301158 |
Method and apparatus for measuring active fluorescence
Some embodiments of the invention provide an apparatus for measuring active fluorescence in liquid samples by using solid-state components. The use of solid-state devices dramatically lowers the...
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7300800 |
Analyte detection system
An analyte detection system utilizing a combination of fluorescent labels for labeling particles and an analyte specific fluorescent analyte detection dye. The particles contain a combination of...
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7298476 |
Method and system for far-field microscopy to exceeding diffraction-limit resolution
The bio-sample (e.g., a live cell) is labeled with a proper number of nanoparticles. Each nanoparticle is pre-co-doped with a controlled ratio of fluorophore donors and acceptors. Two laser pulses...
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7297963 |
Method for determination of fuel thermal stability
A method of evaluating thermal stability of a fuel and an apparatus used therein. The method includes heating the fuel to a given temperature, directing light through the heated fuel a first time...
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7297962 |
Method for performing spacially coordinated high speed fluorometric measurements
An optical imager, such as a microscope for performing multiple frequency fluorometric measurements comprising a light source, such as a laser source is disclosed. The system is used to excite a...
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7297961 |
Fluorescence microscope and observation method using the same
The present invention relates, in general, to a fluorescence microscope and method of observing samples using the microscope and, more particularly, to a fluorescence microscope and method of...
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7294842 |
Camera head for fast reproduction of a vacuum UV spectrometer spectrum
An apparatus for measuring the transport time of impurity particles in a plasma includes a spectrometer, a system for the spatially-resolving conversion into charge of light exiting the...
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7292350 |
Laser system for measurements of the profile of objects
A system for measuring a profile of an object comprising a source creating a beam of electromagnetic energy. An electromagnetic beam receiver spaced from the source for processing an output signal...
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7288227 |
Biochip reader with enhanced illumination and bioarray positioning apparatus
A method of illumination and illumination apparatus are provided in a biochip reader. Illumination is provided by a non-collimated laser source or a light emitting diode (LED). The light is...
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7285790 |
Optical measurement system for living bodies and method thereof
A response period is determined arbitrarily. A satisfactory detecting ability may not be provided because of an artifact or the like contained in a signal. Therefore, an effective detection method...
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7285789 |
Optical device for surface-generated fluorescence
A sample substrate adapted for use with electromagnetic excitation light includes a base and a layer system. The layer system includes a multilayer interference coating with at least two layers...
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7283229 |
Small object identifying device and its identifying method
A small object identifying device and its identifying method according to which a large number of small objects can be identified. In one embodiment, the device includes a dispersion region section...
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7282724 |
Method and system for the analysis of co-localizations
A method and a system for the analysis of co-localizations of dyes present in a specimen. The fluorescence spectra of the dyes present in the specimen are determined. A tolerance region around each...
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7282723 |
Methods and apparatus for processing spectral data for use in tissue characterization
The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks...
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7277169 |
Whole spectrum fluorescence detection with ultrafast white light excitation
A fluorescence detection system for testing a sample having at least one fluorophore. The fluorescence detection system comprises a white light generation system outputting a white light pulse. The...
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7277168 |
Method and system for real-time fluorescent determination of trace elements
A system for real-time fluorescent determination of trace elements comprising transport means for moving a plurality of samples, means for generating a plurality of incident radiation pulses of...
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7274447 |
Material porosity pressure impulse testing system
A system and method for determining porosity of a material enables rapid testing of materials by detecting test particle penetration. The material is held by a test chamber wherein a test particle...
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7274446 |
Method and arrangement for the deep resolved optical recording of a sample
A method for depth-resolved optical detection of a specimen comprises the steps of providing a scanning movement over the specimen or at least a part of the specimen of an illumination light...
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7274445 |
Confocal scatterometer and method for single-sided detection of particles and defects on a transparent wafer or disk
A problem in the inspection of transparent wafers and disks is the detection of top surface particles. More precisely, it is being able to assign a scattering site as being due to a particle at the...
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7274028 |
Characterizing fluorescent and/or phosphorescent materials
A method spectrally and temporally characterizing the fluorescence and/or phosphorescence of a material includes using a frequency-domain cross-correlation fluorometer-phosphorimeter employing an...
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7274027 |
Scanning systems and methods with time delay sensing
Methods and systems that excite a test structure with an excitation beam and then sense the response of the test structure after some prescribed time interval with respect to the excitation. One or...
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7271952 |
Microscope imaging apparatus and biological-specimen examination system
A microscope imaging apparatus and a biological-specimen examination system that can accurately carry out measurement even for an object under examination having substantial brightness...
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7271886 |
Uncaging device
Uncaging devices that can be used to uncage photoactivatable caged components are provided. Consistent, uniform and/or high throughput processing of reactions and assays that include caged...
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7268868 |
Anti-resonant waveguide sensors
An improved method of analyzing target analytes in a sample is described. The method is based on anti-resonant guided optical waveguides which enables a strongly improved light-target interaction...
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7268355 |
Excimer UV fluorescence detection
A UV fluorescence detection system is provided comprising a dielectric barrier-discharge excimer lamp, an applied excitation source for communication with the excimer lamp; a fluorescence chamber...
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RE39806 |
Scintillator panel, radiation image sensor, and methods of making the same
A scintillator panel ( 2 ) comprises a radiation-transparent substrate( 10 ), aflat resin film ( 12 ) formed on the substrate ( 10 ), a reflecting film ( 14 ) formed on the flat resin film ( 12 ),...
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7265825 |
Apparatus for measuring fluorescence lifetime
An apparatus for measuring fluorescence lifetime includes a pulse laser source that generates a pulse excitation light, a detector that detects a fluorescence generated from a sample by irradiating...
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7265363 |
Microscope examination method, optical stimulation apparatus, and microscope examination apparatus
While carrying out microscope examination, it is possible to specify a position to be irradiated with optical stimulus light and to accurately apply an optical stimulus to the specified irradiation...
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7262842 |
Device for referencing fluorescence signals
The invention relates to a device for referencing fluorescence signals and/or calibration of fluorescence detection systems, whereby the device comprises an essentially non-fluorescing support, on...
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7262840 |
Method for detection of pathogenic microorganisms
A method for the detection and identification of pathogenic microorganisms using Raman scattered light and emitted light. The method may include passing the Raman scattered light and emitted light...
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7262420 |
Secure tag validation
A reader for validating a secure tag. The reader comprises: an optical source operable to illuminate the secure tag; a processor coupled to the optical source and operable to activate and...
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7262419 |
Fluorescence absorption microscopy
A microscopy technique for viewing regions where a sample absorbs, as opposed to emits, fluorescent light. The technique includes illuminating a sample with an exciter light in order to generate...
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7259847 |
Use of optical diffraction elements in detection methods
The invention relates to a method for determining luminescent molecules by means of optical excitation in confocal measurement volumes using a diffractive optical element. The method is...
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7257289 |
Spectral microscope and method for data acquisition using a spectral microscope
A spectral scanning microscope and a method for data acquisition using a spectral scanning microscope are disclosed. A computer system is provided that encompasses a memory and a database. In...
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7256892 |
Measuring instrument and fluorometric method
A measuring instrument that comprises a light source unit 1 capable of emitting light having different wavelengths, a light receiving unit 2 that outputs an electrical signal corresponding to...
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7256887 |
Determining the suitability of an optical material for the production of optical elements, corresponding device, and use of said material
The method tests the suitability of an optical material having a radiation-induced absorption, especially of an alkali or alkaline earth halide, for production of an optical element exposed to...
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7253420 |
Scanning microscope system
A scanning microscope system includes an optical microscope observation unit that irradiates the sample with excitation light, and forms an optical image from fluorescence emitted from a sample....
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7250612 |
Devices and methods capable of authenticating batteries
Battery-powered devices which are capable of authenticating batteries. In one embodiment, a device comprises: a battery, an excitation source, a photodetector, and an operating system. The device...
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7248361 |
Fluorescence reader based on anti-resonant waveguide excitation
A sample detection system including an anti-resonant waveguide, including a sample having a first index of refraction, a top layer and a substrate surrounding the sample, where the top layer has a...
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7248360 |
Polychronic laser scanning system and method of use
A system for laser scanning provides spectral flexibility needed for the spectroscopic monitoring of highly multiplexed samples, such as cellular and particle assays in whole blood or other...
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7247842 |
Method and system for scanning apertureless fluorescence mircroscope
Methods and systems for operating an apertureless microscope for observing one or more features to a molecular sensitivity on objects are described. More particularly, the method includes moving a...
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7247443 |
Sensor constructs and detection methods
Sensor constructs for detecting the presence of an analyte in a sample comprise a molecular scaffold, a pair of labels which interact via Förster resonance energy transfer, and at least one...
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