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7391512 Integrated optoelectronic system for measuring fluorescence or luminescence emission decay  
An optoelectronic system for measuring fluorescence or luminescence emission decay, including (a) a light source being a light emitting diode, a semiconductor laser or a flash tube; (b) a first...
7381973 Analyzer system and method incorporating excimer UV fluorescence detection  
A system for measuring the amount of sulfur in a sample is provided comprising a UV fluorescence detector for determining the sulfur dioxide content of the sample and an analyzer for receiving the...
7381972 System and method for light fluorescence detection  
A device for determining the presence or absence of at least one substance is described. The device includes an illumination component including at least one light emitting diode in the forward...
7375811 Fatigue-degree evaluation device  
A fatigue-degree evaluation device is provided for easily evaluating a degree of fatigue of a living body. Embodiments include a device wherein fluorescent light generated via a liquid excreted...
7372570 Incident light redistribution to compensate for radial gradient in detector  
Nonuniformities in the efficiency of detection of individual fluorescing reaction mixtures in a well plate with a two-dimensional array well array are corrected. The nonuniformities arise both from...
7369308 Total internal reflection fluorescence microscope  
A total internal reflection fluorescence microscope includes a light source which generates laser light having a plurality of wavelengths, a focal optical system which irradiates the laser light...
7365344 Scanning fluorescent microscope  
A scanning fluorescent microscope includes a light source which irradiates a sample with an exciting light pulse, and a splitter which splits fluorescent photons emitted from the sample excited by...
7362432 Method and systems for dynamic range expansion  
Methods and systems for expanding the dynamic range of a system are provided. One method includes splitting fluorescent light emitted by a particle into multiple light paths having different...
7361906 Biopolymer array substrate thickness dependent automated focus-distance determination method for biopolymer array scanners  
A method and system for determining a biopolymer array substrate thickness dependent optimal focus distance for scanning a molecular array by a molecular array scanner are provided. A reference...
7355701 Spectroscopy analysis apparatus  
A spectroscopy analysis apparatus contains a focusing unit which focuses light from a light source on a sample, an optical scanner which scans the light on the sample, an optical detector which...
7352459 Scanning Spectrophotometer for high throughput fluorescence detection and fluorescence polarization  
A fluorescence spectrophotometer system may be implemented in scanning fluorescence polarization detection applications. A wavelength and area scanning fluorescence spectrophotometer system may...
7348573 Excitation and emission filter  
Systems and methods for detecting fluorescent light by providing a filter assembly including an excitation filter and an emission filter.
7342219 Laser scanning microscope  
A laser scanning microscope includes an acousto-optic element or an electro-optic element in an illumination optical system which introduces a laser beam from a laser beam source of the laser...
7339667 Dark box apparatus for fluoroscopy, fluoroscopy system, and fluoroscopy method  
Noise in a fluorescence image acquired during fluoroscopy is eliminated to present a clear fluorescence image, and the relative positional relationship between the fluoroscopy unit and the specimen...
7339657 Low-cost on-line and in-line spectral sensors based on solid-state source and detectors combinations for monitoring lubricants and functional fluids  
A series of optical spectral sensors is based on a combination of solid-state sources (illumination) and detectors housed within an integrated package that includes the interfacing optics and...
7336355 Fluorescence spectroscopic apparatus  
There is provided a fluorescence spectroscopic apparatus includes an exciting optical unit configured to irradiate the same sample area with a plurality of excitation lights of different wavelength...
7335898 Method and apparatus for fluorescent confocal microscopy  
A new and improved confocal fluorescence microscope is presented. The new microscope has significant advantages relative to existing implementations of microscope confocal imagers. In common with...
7332727 Method and device for generating ultra-high pressure  
A pressure source material is loaded into a space having constraint device 1 , which is formed partly by optically transparent material 1 a, 1 b , and is disrupted under volume constraint. Light...
7330255 Total internal reflection fluorescence apparatus  
Techniques are provided for illuminating a sample by using total internal reflection (TIR) from a diffraction limited focused annular illumination beam. The illumination forms an affected region...
7330252 Porous silicon on-chip spectroscopy system  
Embodiments of the present invention provide a miniaturized spectroscopy system comprising a light source fabricated from porous silicon. Porous silicon light emitting devices can provide tunable,...
7329880 Multiphoton-excitation laser scanning microscope  
A compact and inexpensive multiphoton-excitation laser scanning microscope for observing fluorescence by multiphoton excitation having a plurality of wavelengths by irradiating a specimen with...
7329860 Confocal imaging methods and apparatus  
The invention provides imaging apparatus and methods useful for obtaining a high resolution image of a sample at rapid scan rates. A rectangular detector array having a horizontal dimension that is...
7324202 Optical system  
An optical system is provided for achieving enhanced rejection of scattered excitation light and superior signal-to-noise performance when reading microplate wells. The optical system uses an axial...
7324200 Fluorescence photometric apparatus  
A fluorescence photometric apparatus which includes a light source, a light irradiating unit configured to condense light from the light source on a sample by means of an objective lens and...
7323696 Phosphor particle coded beads  
Beads coded with phosphor particles and methods of making and using them are provided.
7323679 Procedure for the optical acquisition of objects by means of a light raster microscope with line by line scanning  
Procedure for the image acquisition of objects by means of a light raster microscope with line by line scanning, whereas a scanning of the probe for the creation of a probe image occurs in scanning...
7319039 Aerosol-based detection of biological agents  
The presence of an aerosol or cloud ( 3 ) of a toxic substance is detected by producing an aerosol ( 17, 5 ) of ligands ( 13 ) to the target substance in a region of sky that contains the target...
7317194 Microscope for performing multiple frequency fluorometric measurements  
An optical imager, such as a microscope for performing multiple frequency fluorometric measurements comprising a light source, such as a laser source is disclosed. The system is used to excite a...
7316930 Use of vertically stacked photodiodes in a gene chip system  
An improved gene chip system is arranged with vertically stacked photodiodes for sensing luminescence of genetic material. When genetic samples are combined with a reagent in an array of wells on a...
7315030 Laser scanning microscope, storage medium storing spectral data acquisition program, and spectral data acquisition method  
A laser scanning microscope enables an observation of a specimen through emitting a laser beam onto the specimen marked by a plurality of fluorescent probes and receiving a fluorescent light back...
7310147 Robotic apparatus for picking of cells and other applications with integrated spectroscopic capability  
A robotic apparatus of the kind having a sample manipulation head with associated positioning system mounted above the main bed of the apparatus, as used for picking of cells, in particular animal...
7309867 Methods and apparatus for characterization of tissue samples  
The invention provides methods for determining the probability that a given region of a tissue sample contains tissue of a given category, such as CIN 1 (cervical intraepithelial neoplasia, grade...
7307718 Determining an analyte by multiple measurements through a cuvette  
A method for measuring the presence or concentration of an analyte in a sample by spectrophotometry: providing an open top cuvette having a sample with an analyte to be measured; providing a light...
7307713 Apparatus and method for inspection of a wafer  
The invention concerns an apparatus and a method for inspection of a wafer. The apparatus encompasses at least one stroboscopic incident-light illumination device for emitting a pulsed...
7307261 Fluorescence detecting apparatus  
A fluorescence detecting apparatus includes: a light source for illuminating the surface of detection of a sample with excitation light; a CCD area image sensor for detecting fluorescence emitted...
7304733 Method and device for conducting the spectral differentiating, imaging measurement of fluorescent light  
A method and a device for image producing measurement of fluorescent light, according to which a sample containing fluorophores of different species is irradiated with excitation light of at least...
7304314 Quantum cross-ambiguity function generator  
A cross-ambiguity function generator (“CAF”) uses properties of quantum mechanics for computation purposes. The CAF has advantages over standard analog or digital CAF function generators, such...
7298476 Method and system for far-field microscopy to exceeding diffraction-limit resolution  
The bio-sample (e.g., a live cell) is labeled with a proper number of nanoparticles. Each nanoparticle is pre-co-doped with a controlled ratio of fluorophore donors and acceptors. Two laser pulses...
7297963 Method for determination of fuel thermal stability  
A method of evaluating thermal stability of a fuel and an apparatus used therein. The method includes heating the fuel to a given temperature, directing light through the heated fuel a first time...
7297962 Method for performing spacially coordinated high speed fluorometric measurements  
An optical imager, such as a microscope for performing multiple frequency fluorometric measurements comprising a light source, such as a laser source is disclosed. The system is used to excite a...
7297961 Fluorescence microscope and observation method using the same  
The present invention relates, in general, to a fluorescence microscope and method of observing samples using the microscope and, more particularly, to a fluorescence microscope and method of...
7294842 Camera head for fast reproduction of a vacuum UV spectrometer spectrum  
An apparatus for measuring the transport time of impurity particles in a plasma includes a spectrometer, a system for the spatially-resolving conversion into charge of light exiting the...
7292350 Laser system for measurements of the profile of objects  
A system for measuring a profile of an object comprising a source creating a beam of electromagnetic energy. An electromagnetic beam receiver spaced from the source for processing an output signal...
7288227 Biochip reader with enhanced illumination and bioarray positioning apparatus  
A method of illumination and illumination apparatus are provided in a biochip reader. Illumination is provided by a non-collimated laser source or a light emitting diode (LED). The light is...
7285790 Optical measurement system for living bodies and method thereof  
A response period is determined arbitrarily. A satisfactory detecting ability may not be provided because of an artifact or the like contained in a signal. Therefore, an effective detection method...
7285789 Optical device for surface-generated fluorescence  
A sample substrate adapted for use with electromagnetic excitation light includes a base and a layer system. The layer system includes a multilayer interference coating with at least two layers...
7282724 Method and system for the analysis of co-localizations  
A method and a system for the analysis of co-localizations of dyes present in a specimen. The fluorescence spectra of the dyes present in the specimen are determined. A tolerance region around each...
7282723 Methods and apparatus for processing spectral data for use in tissue characterization  
The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks...
7277169 Whole spectrum fluorescence detection with ultrafast white light excitation  
A fluorescence detection system for testing a sample having at least one fluorophore. The fluorescence detection system comprises a white light generation system outputting a white light pulse. The...
7277168 Method and system for real-time fluorescent determination of trace elements  
A system for real-time fluorescent determination of trace elements comprising transport means for moving a plurality of samples, means for generating a plurality of incident radiation pulses of...