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6930314 |
Light detection device
Apparatus and methods for optical illumination and/or detection with improved flexibility and/or read speed. The apparatus and methods may include mechanisms for selecting and switching between...
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6927403 |
Illumination system that suppresses debris from a light source
There is provided an illumination system for wavelengths of ≦193 nm. The illumination system includes an object plane, a plane conjugated to the object plane, a first collector between the object...
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6927402 |
Device for detecting different fluorescence signals of a sample support illuminated with different excitation wavelengths
Light sources are provided for generating rays of light of different excitation wavelengths, which can be directed toward the sample support by excitation optics. The fluorescent light emitted each...
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6927401 |
Method of characterizing fluorescent molecules or other particles using generating functions
A method for characterizing fluorescent molecules or other particles in samples comprising the steps of:
a) monitoring fluctuating intensity of fluorescence emitted by the molecules or other...
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6924490 |
Microscope system
A microscope system is provided which includes a single microscope. The system includes a laser source, a light path splitting unit which splits a light path of a laser beam from the laser source...
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6921908 |
Methods for fluorescence detection that minimizes undesirable background fluorescence
The present invention provides a method for the excitation of a fluorescent sample and the measurement of the fluorescent emission. The method of the present invention has the advantage of...
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6919571 |
Micro fluorescent electrophoresis detection system
A micro fluorescent electrophoresis (EP) detection system for detecting fluorescent EP is disclosed. The size of the system is greatly minimized for carrying. The invention uses a laser diode with...
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6914677 |
Device and method for optically measuring the concentration of a substance
The invention relates to a device and a method for optically measuring the concentrations of a substance contained in a fluid medium. With the solution according to the invention the accuracy of...
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6914720 |
Time resolved fluorescence microscope
A time-resolved fluorescence microscope having high spatial and time resolution. Fluorescence from a sample 26 mounted on a confocal inverted optical microscope 19 and excitation laser light...
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6914250 |
Fluorometric detection using visible light
Systems, devices and methods of the present invention are for viewing a pattern of fluorophors capable of fluorescing when exposed to visible light, e.g., fluorescently stained DNA, protein or...
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6912050 |
Phase shift measurement for luminescent light
A phase shift measurement system comprises an excitation system, a luminescent material, and a detection system. The excitation system transfers an excitation light wave. The luminescent material...
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6906859 |
Epi-illumination apparatus for fluorescent observation and fluorescence microscope having the same
An epi-illumination apparatus for fluorescent observation, adjusting light intensities of a plurality of illuminations on a sample over a wide wavelength band continuously and being configured...
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6903816 |
Mirror driving mechanism, and spectroscope and scanning laser microscope comprising mirror which is driven by mirror driving mechanism
A mirror driving mechanism comprises a driver configured to drive at least one mirror which reflects a light flux while adjusting a wavelength width and a wavelength band of the light flux...
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6903817 |
Method for optically detecting chemical species contained in condensed media
A method for detecting chemical species present in a condensed medium including determining characteristic wavelengths and intensity values of back-scattered electromagnetic emission signals due to...
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6900891 |
Optical sensors for the detection of nitric oxide
Optical fiber sensors and fiberless optical sensors for measuring analytes, and in particular nitric oxide, are described utilizing metals, and more particularly, metal colloids. Proteins (or...
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6897953 |
Method for measuring fluorescence, apparatus for measuring fluorescence and apparatus for evaluating sample using it
In a fluorescence measuring method and apparatus, a sample S is irradiated with pulsed pumping light supplied from a pumping light source. Fluorescence generated by the sample S is detected by a...
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6881962 |
Paper fluorescence detection sensor
In the accurate inspection of a paper sheet (for example, the type and authenticity of banknotes) light incident on the paper sheet that is being transported is controlled to be constant. To...
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6878947 |
Device for the simultaneous detection of radiation of different wavelengths
A device for the simultaneous detection of radiation of different wavelength, comprising a number of base modules arranged one on top of the other, an optical module and an electronic module. One...
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6878949 |
Gel imaging and excision
A robot for imaging and excision of two-dimensional fluorescent gels. An array detector is mounted in the roof of the robot to image down onto a gel dish placed on a light table. Fluorescence is...
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6870166 |
Maximum sensitivity optical scanning system
A maximum sensitivity optical scanning system is disclosed. It finds use in a variety of applications, including the reading of biopolymeric arrays. It operates by scanning sample at a setting...
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6870165 |
Multi-color multiplexed analysis in a bio-separation system
A multi-channel and multi-color bio-separation detection method and apparatus in which a single detector is coupled to a plurality of radiation sources, in a one detector/many radiation sources...
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6867420 |
Solid-state detector and optical system for microchip analyzers
A miniaturized optical excitation and detector system is described for detecting fluorescently labeled analytes in electrophoretic microchips and microarrays. The system uses miniature integrated...
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6867421 |
In-line process for monitoring binder dosage and distribution on a surface and apparatus useful therefor
A method and apparatus for determining binder dosage and distribution on a substrate. The apparatus employed is made up of:
a) a source of long wave ultraviolet light positioned so that...
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6864975 |
Method of and system for analyzing a sample containing a plurality of fluorescent substances
The present invention proposes a method of and system for analyzing samples (particularly, bio-samples), wherein the continuous spectrum white light pulse generated from an ultra-short optical...
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6862093 |
Ruggedized forensic light source
A forensic light source uses a pair of filter wheels to achieve a combination of the characteristics of filters on different wheels and may include a housing which supports the light, filter wheels...
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6855941 |
Laser microscope
A multiphoton excitation scanning laser microscope employs a laser beam source for oscillating a pulse laser beam having a wavelength range. A multiphoton excitation phenomenon takes place in a...
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6852986 |
Fluorometer with low heat-generating light source
This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present...
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6850323 |
Locally enhanced raman spectroscopy with an atomic force microscope
An atomic force microscope (AFM) tip is used to selectively produce surface enhanced Raman scattering (SERS) for localized Raman spectroscopy. Spectra of thin films, undetectable with a Raman...
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6849855 |
Method for marking and identifying objects coated with up-conversion material
A method of marking and identifying an object ( 10 ) by the marking consists of applying to an object ( 10 ) an up-conversion material ( 12 ), then irradiating the object ( 10 ) with infrared...
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6844965 |
Apparatus for optical scanning of multiple specimens
An apparatus for optical scanning of multiple specimens ( 1 ) and/or specimen regions, the specimens ( 1 ) being associated with a specimen receiving device ( 2 ) and being optically scannable by a...
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6844558 |
Material measure and position measuring device comprising such a material measure
A material measure includes a carrier substrate having a surface that includes at least one track having first porous subsections and second subsections. The first porous subsections and the second...
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6844963 |
Double-resonance-absorption microscope
The present invention provides various embodiments of a double-resonance-absorption microscope which realizes a super-resolution by using double resonance absorption. In particular, a...
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6838680 |
Multiplexed fluorescent detection in microfluidic devices
An optical detection and orientation device is provided comprising a housing having an excitation light source, an optical element for reflecting the excitation light to an aspherical lens and...
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6839375 |
On-line quality control of the key optical components in lithography lasers using laser induced fluorescence
Some of the key optical components of lithography lasers are very sensitive to intensive UV radiation. Intensive UV radiation can cause color center formation in these components. The color centers...
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6838681 |
Detection and making of ultralow lead contaminated UV optical fluoride crystals for <200nm lithography
The invention provides a method of detecting sub-ppm lead impurity levels in a below 200 nm transmitting optical calcium fluoride crystal. The method includes providing a below 200 nm wavelength...
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6839134 |
Light measuring device avoiding influence of fluorescence or phosphorescence of lenses and filters in optical path
At the time of analytical measurement of a sample by the fluorescence measuring device or the phosphorescence measuring device, both the optical path of exciting light emitted from the light source...
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6835933 |
Spectrum measuring apparatus
A spectrum measuring apparatus for measuring infrared, Raman and fluorescence spectra. The spectrum measuring apparatus includes an infrared source, a laser source, an infrared up-conversion object...
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6835946 |
Image reading method and apparatus
An image reading apparatus is adapted for irradiating an image carrier including a labeling substance contained in two-dimensionally distributed spots with a stimulating ray and photoelectrically...
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6833916 |
High efficiency, large field scanning microscope
A fluorescent optical imaging system ( 10 ) produces two separate spots (S 1 and S 2 ) on a sample ( 12 ) by a pair of excitation laser beams (B 1 and B 2 ) that are generated by first and second...
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6833915 |
Optical diagnosis system for small animal imaging
Optical diagnosis system for small animal imaging, in which the animal which has been arranged on a bearing plate and treated with an activatable optical contrast medium is irradiated by an...
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6831279 |
Laser diode-excited biological particle detection system
Apparatus is provided for detection of viable and potentially hazardous biological particles in a population which may be dispersed in fluid flow. The particles are characterized as biological and...
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6831734 |
Method and apparatus for automated, in situ material detection using filtered fluoresced, reflected, or absorbed light
A method and apparatus for detection of a particular material, such as photo-resist material, on a sample surface. A narrow beam of light is projected onto the sample surface and the fluoresced...
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6831739 |
Compression-bonded probe window
In an optical measurement probe of the type which incorporates a window configuration suited to on-line process control and other applications this invention provides an improved technique for...
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6829051 |
Optical apparatus
An optical apparatus including an illuminating optical system for illuminating a sample with light from a light source, a first wavelength selecting member, a light beam splitter for directing...
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6828567 |
Optical detection in a multi-channel bio-separation system
A multi-channel bio-separation detection method and apparatus in which a single detector is coupled to a plurality of radiation sources, in a one detector/many radiation sources configuration. Each...
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6828568 |
Process for testing of fluophors and device for carrying out the process
A method and apparatus for increasing the emission amount of red such that it is made the same as the emission amount of green and blue, to enable the application state of the fluophors to be...
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6825929 |
Simultaneously reading different regions of a chemical array
A method of interrogating an addressable array having a plurality of different chemical features. The method may include simultaneously illuminating different regions of the array with light of...
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6825927 |
Controller for a fluorometer
A method and apparatus relating to a controller for controlling a light emitting array by setting a power level provided to each individual light emission source within the light emitting array is...
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6825928 |
Depth-resolved fluorescence instrument
A fluorescence instrument illuminates the surface of tissue with light of a selected wavelength and light emanating from the tissue due to fluorescence is collected. The size of the effective...
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6822242 |
Image data producing method and apparatus
An image data producing apparatus includes comprising at least one stimulating ray source for emitting a stimulating ray, a stage on which an image carrier including independently formed and...
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