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7062311 |
Fluorescence observing apparatus
A fluorescence observing apparatus including a light source for emitting excitation light, an excitation light irradiation section for irradiating the excitation light to a sample, and a...
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7057185 |
Maximum sensitivity optical scanning system
A maximum sensitivity optical scanning system is disclosed. It finds use in a variety of applications, including the reading of biopolymeric arrays. It operates by scanning sample at a setting...
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7053384 |
Reference device for evaluating the performance of a confocal laser scanning microscope, and a method and system for performing that evaluation
A reference device for evaluating the performance of a confocal laser scan microscope. The reference device comprises a substrate ( 53 ) and reference fluorescing matter distributed over a surface...
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7054003 |
Simultaneously reading different regions of a chemical array
A method of interrogating an addressable array having a plurality of different chemical features. The method may include simultaneously illuminating different regions of the array with light of...
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7041980 |
Exchangeable component of a textile machine with a surface coating or surface treatment and a means for the detection thereof
An exchangeable component of a textile machine with a surface coating or a treated surface within which color elements are embedded is provided. The color elements in the surrounding area of the...
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7041986 |
Device for discrimination of fluorescence lifetimes and uses therefor
The present invention provides methods for determining fluorescence lifetime of a fluorophor or an optical sensor using frequency domain gated detection. The method comprises the steps of exciting...
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7042565 |
Fluorescent microarray analyzer
A fluorescent microarray analyzer includes a light source for emitting a light beam, a light processing unit for focusing the light beam on the biochip and exciting fluorescent targets on the...
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7034317 |
Method and apparatus for limiting scanning imaging array data to characteristics of interest
A method and system for limiting the amount of image data to be captured by a scanning imaging array. A low-resolution preliminary image of an object is acquired. Data from the preliminary image is...
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7030371 |
Luminescence characteristics detector
Security documents or articles carrying luminescent marker compounds which show a time-deferred emission characteristic are authenticated by a method and device which allows for rapid extraction of...
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7027150 |
Apparatus for measuring the concentration of a species at a distance
Corrosion of refractory silica brick and air quality issues due to particulate emissions are two important glass manufacturing issues that have been tied to sodium vapor and its transport...
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7019830 |
Process and apparatus for qualitative and quantitative analysis of an analyte
A process for qualitative and quantitative analysis of an analyte in a solution includes irradiating a first chromophore with an electro-magnetic radiation while simultaneously moving an...
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7019309 |
Tripartite fiber-coupled fluorescence instrument
A non-linear fluorescence microscope or endoscope includes: (a) a source of coherent light suitable to initiate non-linear fluorescence in a sample of interest located at a sample region; (b) a...
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7015485 |
Laser scanning microscope, semiconductor laser light source unit, scanning unit for a laser scanning microscope, and method of connecting semiconductor light source to scanning microscope
A laser scanning microscope according to the present invention is a laser scanning microscope which scans a laser beam on a sample by a scanning optical system in a scanning optical system main...
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7016087 |
Photon efficient scanner
A system for optical interrogation of a sample adaptable for multiple wavelength illumination and multiple wavelength fluorescent or luminescent light collection, wherein the illumination...
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7015486 |
Fluorescence image acquisition apparatus and imaging system comprising such an apparatus
The invention concerns an image acquisition apparatus comprising a UV radiation source ( 29 ) capable of making fluorescent supports ( 1 ) whereof the images are to be acquired, a window ( 21 )...
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7015484 |
Multi-dimensional fluorescence apparatus and method for rapid and highly sensitive quantitative analysis of mixtures
Apparatus and methods are provided for rapid and sensitive quantitative analysis of a sample's fluorescence decay properties. A repetitively pulsed excitation light source generates pulsed...
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7015444 |
Optical-scanning examination apparatus
The invention provides an optical-scanning examination apparatus with a simple configuration, in which the resolution of acquired images can be freely changed and in which the fluorescence image...
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7016043 |
Quality evaluation method and apparatus for non-bran rice
A quality evaluation method and apparatus for non-bran rice evaluate quality or taste of non-bran rice by identifying proportions of a hull layer, an aleurone layer, an endosperm layer, which...
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7009699 |
Method for investigating a sample
A method for investigating specimens, wherein a spectral splitting of the radiation coming from the specimen is carried out for specimen points or point distributions, for the operation of a laser...
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7009161 |
Scanning microscope
The scanning microscope includes an illumination beam path, microscope optics and at least one light source which generates an excitation light beam of a first wavelength and a second light beam of...
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7005653 |
Near-field intra-cellular apertureless tomographic imaging
A method and apparatus for near-field intra-cellular apertureless tomographic imaging uses sub-wavelength nano-particle in a cell which generates tomographic projections. A detector detects and...
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7005654 |
Method for microscopy, and microscope
The invention discloses a method for microscopy in which a specimen is illuminated with pulsed illuminating light that comprises light from a spectral region, and detection light proceeding from...
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7002688 |
Multilens optical assembly for a diagnostic device
A diagnostics apparatus for detecting fluorescence events related to the presence of an analyte in a sample is disclosed. The apparatus includes a housing, a source of excitation light and a...
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7002162 |
Instrument for measuring lifetime of fluorescene
A fluorescence component that passes through a region of a detection medium where a change in refractive index has been induced through a nonlinear optical effect produced in the detection medium...
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6992762 |
Method and apparatus for time resolved optical imaging of biological tissues as part of animals
There is provided a method and system for collecting optical data for use in time resolved optical imaging wherein light is directionally propagated through free-space optics to impinge on a...
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6992303 |
Detecting emitters of electromagnetic radiation, in particular fluorophore labeled substances
The performance of devices for the detection of fluorophore labelled substances in an electrophoretic separation medium is improved by rescanning lines or pixels which caused saturation of an...
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6991939 |
Optical array device and methods of use thereof for screening, analysis and manipulation of particles
Methods and devices are provided for the trapping, including optical trapping; analysis; and selective manipulation of particles on an optical array. A multi-channel device parcels a light source...
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6992761 |
Broad range light detection system
Broad-range light-detection systems, including components and methods of use thereof. These systems may include apparatus and methods for detecting light with increased speed and/or detection...
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6989277 |
Method for immunoassays based on infrared reflection absorption spectroscopy
This invention relates to a method for immunoassays based on infrared reflection absorption spectroscopy that utilizes proteins such as antigen and antibody that have specific absorptions in...
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6987274 |
Light detection and imaging system and method including an array of sensors
A light detection system for imaging an object including a light source, an object, a first substrate with a sensor arranged on a side of the first substrate opposite from the light source, the...
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6985225 |
Fluorescence-measuring system
The invention relates to a fluorescence-measuring system as can be employed for high-throughput screening in drug development. The arrangement for fluorescence excitation contains a...
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6984828 |
Quantified fluorescence microscopy
The present invention relates to calibration apparatuses, methods or tools used in microscopy. A calibration tool for fluorescent microscopy includes a support, a solid surface layer including a...
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6980294 |
Biomolecule analyzer
A biomolecule analyzer of the present invention analyzes dynamic behaviors of biomolecules, and comprises image obtaining means for obtaining an image corresponding to at least one observation area...
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6977724 |
Method for spectral analysis, and scanning microscope
A method for spectral analysis of the light proceeding from a specimen using a multi-band detector comprises the steps of defining an overall spectral region; from the overall spectral region,...
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6974673 |
Coupled capillary fiber based waveguide biosensor
An evanescent-wave optical biosensor includes a hollow optical waveguide, preferably in the form of a light-conductive capillary, surrounding a central waveguide preferably in the form of an...
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6969605 |
Miniature immuno-optical rapid analyte sensor platform
A hand held, self-contained, automatic, low power and rapid sensor platform for detecting and quantifying a plurality of analytes. A sample solution potentially containing an unknown amount of an...
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6970246 |
Method and apparatus for detecting fluorescence of a sample
The present invention relates to an apparatus and a method for detecting the fluorescence of a sample, wherein the apparatus comprises excitation light source located on the same side of the sample...
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6965105 |
Scanning system and method for scanning a plurality of samples
A system for detecting fluorescence emitted from a plurality of samples in a sample tray is provided. The system generally includes a plurality of lenses positioned in a linear arrangement, a...
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6963397 |
Fluorometry and fluorometric device and substrate suitable therefor
To provide a method of efficiently removing excitation light in a device for measuring fluorescence emitted from samples on a measuring surface of a substrate while illuminating the samples with...
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6962820 |
Analyte detection system
An analyte detection system utilizing a combination of fluorescent labels for labeling particles and an analyte specific fluorescent analyte detection dye. The particles contain a combination of...
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6956221 |
Tunable cross-coupling evanescent mode optical devices and methods of making the same
Tunable cross-coupling evanescent mode optical devices and methods of making the same are described. In one aspect, a tunable optical device includes a first layer, a second layer, a metal layer...
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6956647 |
Method for operating a laser scanning confocal microscope system and a system thereof
A method for operating a confocal microscope system includes deflecting a light beam on a specimen with at least one beam deflection device. The position of the light beam is stepped with at least...
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6952259 |
Method of detecting the presence of a liquid in a mix
The invention relates to a method of detecting the presence of a liquid introduced into a mix of constituents. The method comprises the following steps:
excitation of the mix by a light...
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6949754 |
Apparatus for measuring in particular luminescent and/or fluorescent radiation
An apparatus for selected measurement of, in particular, luminescent and/or fluorescent radiation has a plurality of measurement light paths (M 1 , M 2 , M 3 ), which each have their own measuring...
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6946664 |
Specimen slides and methods and uses thereof
Emboidments are presented to improve spatial resolution or sensitivity in measuring fluorescent layers, including an embodiment wherein a specimen slide is provided which is not fluorescent by...
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6943357 |
Thermal barrier coatings, components, method and apparatus for determining past-service conditions and remaining life thereof
A method for determining past-service conditions and/or remaining useful life of a component of a combustion engine and/or a thermal barrier coating (“TBC”) of the component comprises providing...
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6940598 |
Multi-channel optical detection system
An apparatus for thermally controlling and optically interrogating a reaction mixture includes a vessel [ 2 ] having a chamber [ 10 ] for holding the mixture. The apparatus also includes a...
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6940641 |
Fluorescence observation apparatus
A fluorescence observation apparatus includes a light source, an illumination optical system conducting irradiation light from the light source to a specimen, an aperture member provided in the...
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6936827 |
Detecting device for fluorescent-labeled material
A fluorochrome-marked sample is excited with the proper wattage and wavelength of light using an exciter or bandpass filter and beamsplitting mirror device. This causes the sample to emit light of...
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6933962 |
Electronic endoscope with three-dimensional image capturing device
An electronic endoscope comprises a housing and a flexible tube. A light-transmitting optic fiber and a light-receiving optic fiber are provided in the flexible tube. A light source and an imaging...
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