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7283229 |
Small object identifying device and its identifying method
A small object identifying device and its identifying method according to which a large number of small objects can be identified. In one embodiment, the device includes a dispersion region section...
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7282724 |
Method and system for the analysis of co-localizations
A method and a system for the analysis of co-localizations of dyes present in a specimen. The fluorescence spectra of the dyes present in the specimen are determined. A tolerance region around each...
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7282723 |
Methods and apparatus for processing spectral data for use in tissue characterization
The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks...
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7277169 |
Whole spectrum fluorescence detection with ultrafast white light excitation
A fluorescence detection system for testing a sample having at least one fluorophore. The fluorescence detection system comprises a white light generation system outputting a white light pulse. The...
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7277168 |
Method and system for real-time fluorescent determination of trace elements
A system for real-time fluorescent determination of trace elements comprising transport means for moving a plurality of samples, means for generating a plurality of incident radiation pulses of...
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7274447 |
Material porosity pressure impulse testing system
A system and method for determining porosity of a material enables rapid testing of materials by detecting test particle penetration. The material is held by a test chamber wherein a test particle...
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7274446 |
Method and arrangement for the deep resolved optical recording of a sample
A method for depth-resolved optical detection of a specimen comprises the steps of providing a scanning movement over the specimen or at least a part of the specimen of an illumination light...
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7274445 |
Confocal scatterometer and method for single-sided detection of particles and defects on a transparent wafer or disk
A problem in the inspection of transparent wafers and disks is the detection of top surface particles. More precisely, it is being able to assign a scattering site as being due to a particle at the...
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7274028 |
Characterizing fluorescent and/or phosphorescent materials
A method spectrally and temporally characterizing the fluorescence and/or phosphorescence of a material includes using a frequency-domain cross-correlation fluorometer-phosphorimeter employing an...
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7274027 |
Scanning systems and methods with time delay sensing
Methods and systems that excite a test structure with an excitation beam and then sense the response of the test structure after some prescribed time interval with respect to the excitation. One or...
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7271952 |
Microscope imaging apparatus and biological-specimen examination system
A microscope imaging apparatus and a biological-specimen examination system that can accurately carry out measurement even for an object under examination having substantial brightness...
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7271886 |
Uncaging device
Uncaging devices that can be used to uncage photoactivatable caged components are provided. Consistent, uniform and/or high throughput processing of reactions and assays that include caged...
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7268868 |
Anti-resonant waveguide sensors
An improved method of analyzing target analytes in a sample is described. The method is based on anti-resonant guided optical waveguides which enables a strongly improved light-target interaction...
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7268355 |
Excimer UV fluorescence detection
A UV fluorescence detection system is provided comprising a dielectric barrier-discharge excimer lamp, an applied excitation source for communication with the excimer lamp; a fluorescence chamber...
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RE39806 |
Scintillator panel, radiation image sensor, and methods of making the same
A scintillator panel ( 2 ) comprises a radiation-transparent substrate( 10 ), aflat resin film ( 12 ) formed on the substrate ( 10 ), a reflecting film ( 14 ) formed on the flat resin film ( 12 ),...
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7265825 |
Apparatus for measuring fluorescence lifetime
An apparatus for measuring fluorescence lifetime includes a pulse laser source that generates a pulse excitation light, a detector that detects a fluorescence generated from a sample by irradiating...
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7265363 |
Microscope examination method, optical stimulation apparatus, and microscope examination apparatus
While carrying out microscope examination, it is possible to specify a position to be irradiated with optical stimulus light and to accurately apply an optical stimulus to the specified irradiation...
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7262842 |
Device for referencing fluorescence signals
The invention relates to a device for referencing fluorescence signals and/or calibration of fluorescence detection systems, whereby the device comprises an essentially non-fluorescing support, on...
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7262840 |
Method for detection of pathogenic microorganisms
A method for the detection and identification of pathogenic microorganisms using Raman scattered light and emitted light. The method may include passing the Raman scattered light and emitted light...
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7262420 |
Secure tag validation
A reader for validating a secure tag. The reader comprises: an optical source operable to illuminate the secure tag; a processor coupled to the optical source and operable to activate and...
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7262419 |
Fluorescence absorption microscopy
A microscopy technique for viewing regions where a sample absorbs, as opposed to emits, fluorescent light. The technique includes illuminating a sample with an exciter light in order to generate...
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7259847 |
Use of optical diffraction elements in detection methods
The invention relates to a method for determining luminescent molecules by means of optical excitation in confocal measurement volumes using a diffractive optical element. The method is...
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7257289 |
Spectral microscope and method for data acquisition using a spectral microscope
A spectral scanning microscope and a method for data acquisition using a spectral scanning microscope are disclosed. A computer system is provided that encompasses a memory and a database. In...
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7256892 |
Measuring instrument and fluorometric method
A measuring instrument that comprises a light source unit 1 capable of emitting light having different wavelengths, a light receiving unit 2 that outputs an electrical signal corresponding to...
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7256887 |
Determining the suitability of an optical material for the production of optical elements, corresponding device, and use of said material
The method tests the suitability of an optical material having a radiation-induced absorption, especially of an alkali or alkaline earth halide, for production of an optical element exposed to...
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7253420 |
Scanning microscope system
A scanning microscope system includes an optical microscope observation unit that irradiates the sample with excitation light, and forms an optical image from fluorescence emitted from a sample....
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7250612 |
Devices and methods capable of authenticating batteries
Battery-powered devices which are capable of authenticating batteries. In one embodiment, a device comprises: a battery, an excitation source, a photodetector, and an operating system. The device...
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7248361 |
Fluorescence reader based on anti-resonant waveguide excitation
A sample detection system including an anti-resonant waveguide, including a sample having a first index of refraction, a top layer and a substrate surrounding the sample, where the top layer has a...
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7248360 |
Polychronic laser scanning system and method of use
A system for laser scanning provides spectral flexibility needed for the spectroscopic monitoring of highly multiplexed samples, such as cellular and particle assays in whole blood or other...
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7247842 |
Method and system for scanning apertureless fluorescence mircroscope
Methods and systems for operating an apertureless microscope for observing one or more features to a molecular sensitivity on objects are described. More particularly, the method includes moving a...
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7247443 |
Sensor constructs and detection methods
Sensor constructs for detecting the presence of an analyte in a sample comprise a molecular scaffold, a pair of labels which interact via Förster resonance energy transfer, and at least one...
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7238954 |
Optical external cavities having brewster angle wedges
A fluorometer having extremely high spectral resolution and the capability of blocking exciting light. The fluorometer is inexpensive and rugged since it may comprise a device with no moving parts....
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7238942 |
Spectrometric using broadband filters with overlapping spectral ranges
The invention provides a spectrometer ( 10 ) which includes a filter arrangement ( 16,18 ), in addition to any option filters ( 20 ) for limiting an operational wavelength range of the...
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7235792 |
Color-tuned volumetric light using high quantum yield nanocrystals
A light source of coaxially stacked volumetric light cells that can be used either in a lamp or a display. Each light cell is composed of high quantum yield nanocrystals in a silica aerogel matrix...
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7233393 |
Signal noise reduction for imaging in biological analysis
A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset...
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RE39672 |
Method and devices for laser induced fluorescence attenuation spectroscopy
The Laser Induced Fluorescence Attenuation Spectroscopy (LIFAS) method and apparatus preferably include a source adapted to emit radiation that is directed at a sample volume in a sample to produce...
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7227633 |
Optical substrate for enhanced detectability of fluorescence
A sample substrate adapted for use with fluorescence excitation light with a first wavelength. A reflector is disposed on a base. The reflector includes a reflecting multilayer interference coating...
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7227156 |
System and method for attenuating the effect of ambient light on an optical sensor
The present invention provides systems and methods for attenuating the effect of ambient light on optical sensors and for measuring and compensating quantitatively for the ambient light.
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7227126 |
Light detection device
A microplate reader includes a light emitting portion for irradiating each of a plurality of test samples with excitation light, a light receiving portion for receiving return light from each of...
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7224452 |
Method of exciting molecules out of a first state into a second states using an optical signal
In a fluorescence-microscopic method of examining a sample with high spatial resolution, the sample is first cooled to a temperature of below 5° C.; next the cooled sample is transferred out of a...
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7223986 |
Laser scanning microscope
There is disclosed a laser scanning microscope including a first optical scanning system which scans a first laser light for observing a sample on the sample, a first light branch device which...
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7223985 |
Single-channel multicolored correlation analysis
The invention relates to a method for determining luminescent molecules by means of optical excitation in confocal measurement volumes, different species of luminescent molecules in a sample being...
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7221455 |
Integrated, fluorescence-detecting microanalytical system
The present invention relates to a functionally integrated microanalytical system for performing fluorescence spectroscopy. A source of fluorescence-exciting radiation, typically a LED, is...
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7220974 |
Fluorescence detection apparatus and method for excitation light irradiation timing
A fluorescence detection apparatus irradiates a sample with an excitation light having different wavelengths, spectrally detects fluorescence from the sample, and includes: a comparison unit for...
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7217937 |
Automatic identification of suspended particles
The present invention relates to the automatic analysis and identification of different species of particles in a liquid sample using both fluorescent tagging and magnification techniques. A light...
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7215469 |
Confocal microscope
A confocal microscope comprises a light source emitting a polarized light beam, an objective lens irradiating the polarized light beam, which is deflected and scanned by the optical scanner, to the...
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7215426 |
Dark box apparatus for fluoroscopy, fluoroscopy system, and fluoroscopy method
Noise in a fluorescence image acquired during fluoroscopy is eliminated to present a clear fluorescence image, and the relative positional relationship between the fluoroscopy unit and the specimen...
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7214925 |
Pattern method and system for detecting foreign object debris
A method of detecting a non-fixed object in a system ( 12 ) includes applying a light emitting or generating substance to multiple objects. The objects are illuminated with an object illuminator (...
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7211812 |
Entangled photon pair generating apparatus
An entangled photon pair generating apparatus has a first definite polarization photon pair generating apparatus for generating a first definite polarization photon pair beam according to an...
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7209287 |
Confocal optical scanning device
Confocal optical scanning device designed to allow visualization of an object to be observed ( 1107 ) and comprising:
an optical system designed, on the one hand, to focus an illuminating...
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