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7619217 |
High power laser induced acoustic desorption probe
A high power laser-induced acoustic desorption (LIAD) probe is provided for desorbing neutral molecules from a sample analyte on a target into a mass spectrometer for subsequent ionization.
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7619216 |
Charged droplet sprayers
Charged droplet spray is formed from a solution with all or a portion of the charged droplet spray current generated from reduction or oxidation (redox) reactions occurring on surfaces removed from...
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7619215 |
Sample plate for MALDI mass spectrometry and process for manufacture of the same
The present invention relates to a sample microfocusing plate useful in MALDI mass spectrometry having a patterned hydrophobic organosilane coating layer and at least a central portion formed on...
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7619214 |
Spectrometer chip assembly
Method and apparatus for high field asymmetric waveform ion mobility spectrometry in an electronic chip assembly, including an input section, an ion filter and detection section and a control...
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7619213 |
Ion extraction pulser and method for mass spectrometry
The invention provides an ion extraction pulser. The ion extraction pulser may be used independently or in conjunction with a mass spectrometry system. The mass spectrometry system includes an ion...
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7615744 |
Microengineered nanospray electrode system
This invention provides a method of aligning a nanospray capillary needle, a set of electrodes, and a capillary input to a mass spectrometer. The electrode system is formed using microengineering...
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7612335 |
Method and apparatus for ion fragmentation by electron capture
The present invention relates to a method and apparatus for ion fragmentation by electron capture. The present invention provides a method of generating fragment ions by electron capture,...
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7608819 |
Mass spectrometer
The present invention provides a mass spectrometry capable of high-efficiency and high-throughput ECD. An electron source and a two-dimensional combined ion trap in which a magnetic field along and...
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7608818 |
Compact gas chromatography and ion mobility based sample analysis systems, methods, and devices
A compact integrated ion mobility based analysis system includes at least one gas chromatograph (GC) column that receives a sample and elutes constituents of the sample where each of the eluted...
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7605389 |
Particle detector with particle trapping device
A particle detector includes an input port for receiving gas and particulate matter. A charging source generating positively and negatively charged species that charges at least some particulate...
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7605367 |
Explosives detection using differential mobility spectrometry
The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems, methods, and devices...
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7601952 |
Method of operating a mass spectrometer to provide resonant excitation ion transfer
A method of operating a mass spectrometer having a rod set is provided. The rod set has a first end, a second end opposite to the first end, and a longitudinal axis extending between the first end...
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7601951 |
Configuration of an atmospheric pressure ion source
An API source for mass spectrometry which is configured such that all or a portion of its vacuum assembly, including ion focusing and transport electrostatic lenses and ion guides, and two or more...
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7598488 |
Apparatus and method for field asymmetric ion mobility spectrometry combined with mass spectrometry
In a system for analyzing samples by mass spectrometry, analyte ions are analyzed first by field asymmetric ion mobility spectrometry (FAIMS) before being analyzed by a mass analyzer. The analyte...
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7598486 |
Sample plate for glycoprotein analysis by MALDI mass spectrometry and preparation method of the same
The present invention relates to a sample plate for matrix-assisted laser desorption ionization (MALDI) mass spectrometry having a stable glyco-affinity layer of a carboxyalkyl boronic acid or...
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7595487 |
Confining/focusing vortex flow transmission structure, mass spectrometry systems, and methods of transmitting particles, droplets, and ions
Briefly described, embodiments of the present disclosure include: confining/focusing vortex flow transmission structures, mass spectrometry systems including a confining/focusing vortex flow...
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7595486 |
RF multipole ion guides for broad mass range
In a multipole rod ion guide system operated with RF voltages to collect or transmit ions, the inhomogeneity of the electric RF fields is increased in front of the ion guide rods by forming the rod...
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7595484 |
Mass spectrometric method, mass spectrometric system, diagnosis system, inspection system, and mass spectrometric program
The present invention can provide a mass spectrometric system judging whether a measurement target is a substance required by an operator within an actual measurement time, when a substance...
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7588944 |
Method of analyzing C-terminal amino acid sequence of peptide
An analyte peptide is selectively degraded sequentially by using an alkanoic anhydride (S 101 ). The original peptide and a series of degradation reaction products having peptide in which one or...
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7586092 |
Method and device for non-contact sampling and detection
A system for the stand-off detection of trace amounts of analyte materials such as explosives, chemical warfare agents, toxic industrial chemicals, and the like includes an ion source that is...
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7586091 |
Mass spectrometric system and mass spectrometry
After a sample is previously separated into plural components in a channel formed in a microchip ( 353 ), the channel is irradiated along a separation direction with a laser beam from a laser...
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7586090 |
Cell structure, device and method for gas analysis
The invention relates to a gas analysis based on the mobility of ions. The invention relates to a cell structure of an analysis device, the cell structure comprising the reference cell ( 201 ), the...
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7583710 |
Laser and environmental monitoring system
A laser and monitoring system is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present invention...
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7582863 |
Sample support for desorption
An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without...
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7579589 |
Ultra compact ion mobility based analyzer apparatus, method, and system
An ultra compact ion mobility based analyzer in a multilayered chip assembly employing various features such as a ion flow generator to propel ions through an ion mobility based filter and,...
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7579588 |
Base plate for use in mass spectrometry analysis, and method and apparatus for mass spectrometry analysis
A base plate for mass spectrometry analysis is disclosed, which is used in a method in which a substance immobilized on a surface of the base plate is desorbed from the surface by application of...
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7579587 |
Thermally assisted membrane introduction mass spectrometry (MIMS) interface and method of use thereof
A membrane introduction mass spectrometry (MIMS) sampling interface is presented that demonstrates improved online performance for the direct, real-time measurement of semi-volatile organic...
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7576323 |
Point-of-care mass spectrometer system
A point-of-care mass spectrometer system has a sampling system, an ionization component structured to receive a sample for analysis from the sampling system, a mass analyzer structured to receive a...
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7576322 |
Non-contact detector system with plasma ion source
A system for the non-contact detection of analyte chemicals, including explosives, chemical warfare agents and the like, employs a non-equilibrium plasma that is maintained at a temperature...
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7576321 |
Multidimensional ion mobility spectrometry apparatus and methods
Various embodiments of a multi-dimensional ion mobility analyzer are disclosed that have more than one drift chamber and can acquire multi-dimensional ion mobility profiles of substances. The drift...
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7576318 |
Method and apparatus for mass spectrometry
The present invention relates to mass spectrometry and, more particularly, to the scheduling of the steps involved in performing mass spectrometry. The present invention will be of particular...
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7573572 |
Drift tube amplifier and method to amplify current
A drift tube amplifier having an input and an output. The drift tube amplifier including a current-to-voltage converter for converting input current to a voltage, a band pass filter assembly for...
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7573028 |
Ion drive and odor emitter
The present invention relates to an ion drive for selectively isolating an analyte of interest and methods of use thereof. The ion drive includes a substrate with channels therethrough, a...
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7569815 |
GC mass spectrometry interface and method
The invention provides a GC mass spectrometry system, including a column for introducing a sample into the GC mass spectrometry system, a heating source for providing heat to the sample to be...
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7569814 |
Mass spectrometer
A mass spectrometer includes: an ion source for ionizing a specimen to generate ions, an ion transport portion for transporting the ions, a linear ion trap portion for accumulating the transported...
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7569812 |
Remote reagent ion generator
An improved ion source and means for collecting and focusing dispersed gas-phase ions from a remote reagent chemical ionization source (R2CIS) at atmospheric or intermediate pressure is described....
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7564029 |
Sample ionization at above-vacuum pressures
Sample material ionized in a sample receiving chamber is flowed into a sample conduit. Drying gas may also flow into the sample conduit and may be heated. The pressure and length of the sample...
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7564028 |
Vacuum housing system for MALDI-TOF mass spectrometry
The present invention is directed to ion source and vacuum housings for use in MALDI-TOF mass spectrometry which operates with any type of mass analyzer including linear, reflector, or tandem...
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7560717 |
Particle beam irradiation apparatus, treatment planning unit, and particle beam irradiation method
A particle beam irradiation apparatus includes a synchrotron, two scanning electromagnets, a beam delivery apparatus for outputting an ion beam extracted from the synchrotron, and an accelerator...
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7560689 |
High-sensitivity mass spectrometer and method
A sample is sliced obliquely with a blade provided with a metal thin film on the surface, and the slice of the sample adhering to the blade surface is subjected to mass spectrometry. As a result,...
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7560688 |
Mass analysis of mobility selected ion populations
Particular aspects provide novel methods for analysis of ion populations, the methods comprising filtering and selecting an ion population using a low-field dual-gate ion mobility spectrometer...
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7557344 |
Confining ions with fast-oscillating electric fields
The applicants' teachings provide methods, systems, and apparatus useful in operating mass spectrometers and other devices incorporating multipole rod sets or other multi-electrode devices to...
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7557342 |
Electrospray systems and methods
Electrospray systems, electrospray structures, removable electrospray structures, methods of operating electrospray systems, and methods of fabricating electrospray systems, are disclosed.
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7550716 |
Mass spectrometer
The present invention provides a mass spectrometer capable of breaking even a sample molecule having a large molecular weight by a CID process. In an embodiment of the present invention, the mass...
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7547878 |
Neutral/Ion reactor in adiabatic supersonic gas flow for ion mobility time-of-flight mass spectrometry
The content of the invention comprises a concept of reactor for isolated ion transformations induced by collisions with neutral species. This reactor is also an interface between mobility cell and...
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7544933 |
Method and system for desorption atmospheric pressure chemical ionization
A desorption atmospheric pressure chemical ionization (DAPCI) system delivers a primary ion beam composed of an inert, high velocity gas and solvent ions to a surface to effect desorption and...
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7544932 |
Contiguous capillary electrospray sources and analytical devices
Contiguous capillaries useful for separating and electrospraying a fluid comprising analyte and electrolyte are provided. The contiguous capillaries have spray tips at one end of the capillaries...
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7544931 |
Mass-analyzing method
In a mass analysis of a sample, candidate compositions Y of a fragment ion produced by a dissociating operation are deduced from the mass of that fragment ion (Steps S 6 to S 9 ). If the number of...
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7541579 |
Linear quadrupoles with added hexapole fields and method of building and operating same
A mass spectrometer and a method of operating and building same is provided in which a hexapole component is deliberately added to a substantially quadrupole field. This can result in unwanted...
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7541578 |
Microfluidic device and manufacturing method thereof
A method of manufacturing a microfluidic device is described. A substrate having at least one device thereon is provided, wherein the device includes at least one channel. Next, a region beside the...
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