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7619214 |
Spectrometer chip assembly
Method and apparatus for high field asymmetric waveform ion mobility spectrometry in an electronic chip assembly, including an input section, an ion filter and detection section and a control...
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7619213 |
Ion extraction pulser and method for mass spectrometry
The invention provides an ion extraction pulser. The ion extraction pulser may be used independently or in conjunction with a mass spectrometry system. The mass spectrometry system includes an ion...
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7608818 |
Compact gas chromatography and ion mobility based sample analysis systems, methods, and devices
A compact integrated ion mobility based analysis system includes at least one gas chromatograph (GC) column that receives a sample and elutes constituents of the sample where each of the eluted...
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7608817 |
Adiabatically-tuned linear ion trap with fourier transform mass spectrometry with reduced packet coalescence
A linear ion trap traps a plurality of charged particles in a charged particle trap including first and second electrode mirrors arranged along an axis at opposite ends of the particle trap, the...
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7605377 |
On-chip reflectron and ion optics
A microelectronics apparatus comprising a substrate, a pair of grid electrodes coupled to the substrate on opposing sides of a central axis, wherein the grid electrodes are substantially parallel...
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7595155 |
Multiplex detection probes
The present invention comprises detection probes utilizing vesicles or soluble bodies to retain multiple mass tag molecules. The detection probes may be used to simultaneously assay a plurality of...
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7589319 |
Reflector TOF with high resolution and mass accuracy for peptides and small molecules
Many applications in the study of metabolics and proteomics require measurements on peptides and small molecules with high resolving power and mass accuracy. These are often present in complex...
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7589318 |
Mass defect triggered information dependent acquisition
Systems and methods for analyzing compounds in a sample. In one embodiment, a mass spectrometer includes an ion source for emitting a plurality of ions from a sample together with a detector...
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7586088 |
Mass spectrometer and method of mass spectrometry
A mass spectrometer is disclosed comprising an ion mobility spectrometer in combination with a quadrupole mass filter which is scanned in synchronization with the pulsing of ions into the ion...
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7582863 |
Sample support for desorption
An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without...
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7579586 |
Ion selector
The present invention provides an ion selector gate having a first deflection zone 32 and a second deflection zone 34 spaced from the first deflection zone, wherein in use, a single low voltage...
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7579585 |
Method and apparatus for scanning an ion trap mass spectrometer
A mass spectrometer system having an ion trap and a downstream mass spectrometer is provided. A plurality of groups of ions are provided to the ion trap and a first mass-to-charge ratio is...
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7576320 |
Photoelectric ion source photocathode regeneration system
An explosive detection system based on an ion mobility spectrometer detects the presence of trace molecules in air. Such instruments require an ion source to ionize the trace molecules. An ion...
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7576319 |
Systems for differential ion mobility analysis
Disclosed herein are systems, methods and apparatus, for detection and identification of chemical warfare agents (CWAs) using a differential mobility spectrometer.
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7569835 |
Gating grid and method of manufacture
The present invention relates generally to grids for gating a stream of charged particles and methods for manufacturing the same. In one embodiment, the present invention relates to a...
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7566888 |
Method and system for treating an interior surface of a workpiece using a charged particle beam
A method and system of treating an interior surface on an internal cavity of a workpiece using a charged particle beam. A beam deflector surface of a beam deflector is placed within the internal...
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7564043 |
MCP unit, MCP detector and time of flight mass spectrometer
The present invention relates to an MCP unit or the like having a structure intended to achieve a desired time response characteristic, without depending on a limitation imposed by a channel...
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7564028 |
Vacuum housing system for MALDI-TOF mass spectrometry
The present invention is directed to ion source and vacuum housings for use in MALDI-TOF mass spectrometry which operates with any type of mass analyzer including linear, reflector, or tandem...
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7564026 |
Linear TOF geometry for high sensitivity at high mass
The present invention provides a time-of-flight (TOF) mass analyzer. The system includes an analyzer vacuum housing isolated from the evacuated ion source vacuum housing by a gate valve maintained...
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7560689 |
High-sensitivity mass spectrometer and method
A sample is sliced obliquely with a blade provided with a metal thin film on the surface, and the slice of the sample adhering to the blade surface is subjected to mass spectrometry. As a result,...
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7560688 |
Mass analysis of mobility selected ion populations
Particular aspects provide novel methods for analysis of ion populations, the methods comprising filtering and selecting an ion population using a low-field dual-gate ion mobility spectrometer...
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7557343 |
Segmented rod multipole as ion processing cell
A method and apparatus for processing ions in mass spectrometry is provided. The apparatus includes an ion processing cell having segmented multipole rods and a means for admitting reactive reagent...
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7550720 |
Apparatus and method for MALDI source control with external image capture
A method of MALDI sample plate processing includes capturing an image of a plate positioned outside a mass spectrometer. The image is processed to identify one or more attributes of an individual...
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7547880 |
Drift tube for an ion mobility spectrometer with integrated gas channel
A drift tube for an ion mobility spectrometer is assembled from stacked tube segments and has electrodes that generate an electric drift field and are electrically contactable from the outside of...
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7547878 |
Neutral/Ion reactor in adiabatic supersonic gas flow for ion mobility time-of-flight mass spectrometry
The content of the invention comprises a concept of reactor for isolated ion transformations induced by collisions with neutral species. This reactor is also an interface between mobility cell and...
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7541576 |
Method of multiplexed analysis using ion mobility spectrometer
A method for analyzing analytes from a sample introduced into a Spectrometer by generating a pseudo random sequence of a modulation bins, organizing each modulation bin as a series of submodulation...
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7534996 |
Velocity imaging tandem mass spectrometer
A mass spectrometer that employs ion velocity mapping. The mass spectrometer includes velocity mapping ion optics that focus the ions based on their velocity. The focused ions are then directed...
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7528367 |
Ion mobility spectrometer
An ITMS includes an inlet for receiving a sample that will be tested for a substance of interest. The inlet communicates with an ionization chamber and a drift chamber communicates with the...
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7528366 |
Method and apparatus for multiplexing plural ion beams to a mass spectrometer
A method and apparatus for multiplexing plural ion beams to a mass spectrometer. At least two ion sources are provided with means of transporting the ions from the ion sources to separate...
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7521673 |
Wide range, very high resolution differential mobility analyzer (DMA)
The resolution of a differential mobility analyzer (DMA) and the range of valid mobility values for the charged particles that it can detect are increased. The DMA makes use of a flat configuration...
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7518107 |
Methods and apparatus for time-of-flight mass spectrometer
Disclosed are methods and apparatus for compensating for mass error for a time-of-flight mass spectrometer. A reference flight distance for a pulse of ions corresponding to a reference temperature...
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7514676 |
Method and apparatus for selective filtering of ions
An adjustable, low mass-to-charge (m/z) filter is disclosed employing electrospray ionization to block ions associated with unwanted low m/z species from entering the mass spectrometer and...
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7514675 |
Mass spectrometer
The present invention provides a single set of mass spectrometer capable of selectively performing the following two modes of analyses according to the purpose of analysis: the first mass...
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7507953 |
Obtaining tandem mass spectrometry data for multiple parent ions in an ion population
This invention relates to tandem mass spectrometry and, in particular, to tandem mass spectrometry using a linear ion trap and a time of flight detector to collect mass spectra to form a MS/MS...
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7504621 |
Method and system for mass analysis of samples
A system and method of analyzing a sample is described. The system includes an ion source and a deflector for producing a plurality of ion beams each of which is detected in distinct detection...
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7504620 |
Method and apparatus for time-of-flight mass spectrometry
A method and apparatus for time-of-flight (TOF) mass spectrometry. The apparatus improves the ion focusing properties in an orthogonal direction and permits connection with an...
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7501621 |
Data acquisition system for a spectrometer using an adaptive threshold
A data acquisition system and method are described that may be used with various spectrometers. The data acquisition system may include an ion detector and a processing circuit. The processing...
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7501620 |
Laser irradiation mass spectrometer
The present invention provides a laser irradiation mass spectrometer capable of analyzing components of living tissue or living cells with high accuracy. It includes a laser unit for irradiating a...
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7498570 |
Ion mobility spectrometer
An ion mobility spectrometer is described having an ion filter in the form of multiple parallel ion channels defined by conductive layers separated by non-conductive layers. A time-varying electric...
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7495231 |
MALDI sample plate imaging workstation
The invention provides an apparatus for producing an image of a global surface of an ion source sample plate that is exterior to an ion source. In general terms, the apparatus contains a sample...
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7493225 |
Method for calibrating mass spectrometry (MS) and other instrument systems and for processing MS and other data
A method for obtaining at least one calibration filter for a Mass Spectrometry (MS) instrument system. Measured isotope peak cluster data in a mass spectral range is obtained for a given...
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7491931 |
Power supply regulation using a feedback circuit comprising an AC and DC component
In various aspects, ion sources, mass spectrometer systems, and a power supply circuit coupled to a feedback circuit are provided. A power supply is provided that includes at least the power supply...
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7491930 |
Hooked differential mobility spectrometry apparatus and method therefore
Disclosed are a device and method for improved interfacing of differential mobility spectrometry (DMS) or field asymmetric waveform ion mobility spectrometry (FAIMS) analyzers of substantially...
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7491549 |
Apparatus for desorption and ionization of analytes
This invention relates generally to methods and apparatus for desorption and ionization of analytes for the purpose of subsequent scientific analysis by such methods, for example, as mass...
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7485872 |
Large area, pico-second resolution, time of flight detectors
A detector for detecting a particle is disclosed. The detector includes a charge emitter that emits a charge in response to receipt of the particle, an anode for receiving the emitted charge, and...
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7482583 |
Time of flight mass spectrometer
In a time of flight mass spectrometer (TOFMS) having a flight space in which ions fly in a loop orbit formed by a plurality of electric sector fields, the present invention provides a simple...
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7482582 |
Multi-beam ion mobility time-of-flight mass spectrometry with multi-channel data recording
The content of the invention comprises a concept of multi-beam ion pre-selection from a single sample, coordinated mobility (against the gas flow) separation, cooling ions in supersonic gas flow...
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7482580 |
Dynamic adjustment of ion monitoring periods
Methods, systems and computer readable media for dynamically controlling a time period of ion detection by an ion detector of a mass spectrometer. A current resulting from conversion of an output...
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7479630 |
Method and apparatus for flow cytometry linked with elemental analysis
An apparatus ( 100 ) for sequentially analyzing particles such as single cells or single beads, by spectrometry. The apparatus, an elemental flow cytometer, includes means ( 102 ) for sequential...
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7479629 |
Multichannel rapid sampling of chromatographic peaks by tandem mass spectrometer
Systems and methods for optimizing the analysis of co-eluting compounds during a cycle of a tandem mass spectrometer system are provided. The tandem mass spectrometer system switches fast from...
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