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7141787 |
Detector for a co-axial bipolar time-of-flight mass spectrometer
A detector for a coaxial bipolar time-of-flight mass spectrometer is described. The detector includes a microchannel plate, a scintillator disposed in parallel relation to said microchannel plate,...
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7138642 |
Ion source with controlled superposition of electrostatic and gas flow fields
Ion source devices with controlled superposition of electrostatic and gas flow fields to effect rapid collisional cooling with improved ion collection and collimation, analytical apparatus...
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7129479 |
Method and system for introducing an analyte into an ion mobility spectrometer
A system and method for introducing and analyzing a sample containing an analyte using an ion mobility spectrometer are described. The system includes a temperature module for adjusting the...
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7129483 |
Laser desorption and ionization mass spectrometer with quantitative reproducibility
Laser desorption/ionization time-of-flight mass spectrometer (“LDI-TOF-MS”) devices, and methods, that accurately measure the mass of analytes contained in a sample and which also measure the...
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7129480 |
Multipath data acquisition system and method
Improved data acquisition systems and methods that enable large numbers of data samples to be accumulated rapidly with low noise are described. In one aspect, a data acquisition system includes an...
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7126114 |
Method and system for mass analysis of samples
A system and method of analyzing a sample is described. The system includes an ion source and a deflector for producing a plurality of ion beams each of which is detected in distinct detection...
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7122793 |
Ion detecting apparatus and methods
Ion injection in a drift tube apparatus for mobility spectrometry was accomplished without conventional ion shutters such as the Bradbury-Nielson or similar designs common to such drift tubes....
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7119328 |
System for DMS peak resolution
An apparatus for identification of chemical species by measurement of mobility as a function of high electric field and for generating unique compound-dependent signatures based on ion mobility at...
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7119331 |
Nanoparticle ion detection
A nanoparticle ion detector includes an ion trap that receives charged particles ejected from a mass selection device. A laser beam illuminates the particles to induce fluorescence, which is...
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7115859 |
Time- of flight mass spectrometers for improving resolution and mass employing an impulse extraction ion source
A miniature time-of-flight mass spectrometer (TOF-MS) and method for increasing the collection efficiency of laser-desorbed ions in a miniature time-of-flight mass spectrometer (TOF-MS) is...
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7112784 |
Method of mass spectrometry and a mass spectrometer
A method of mass spectrometry is disclosed wherein a gas collision cell is repeatedly switched between a fragmentation and a non-fragmentation mode. Parent ions from a first sample are passed...
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7109478 |
Method and apparatus for automating an atmospheric pressure ionization (API) source for mass spectrometry
The present invention provides an apparatus and method for automated and rapid loading of a large number of samples for mass spectrometric analysis using various ionization methods (e.g. matrix...
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7109475 |
Leading edge/trailing edge TOF detection
Disclosed are a time-of-flight mass spectrometer and signal processing electronics. The signal processing electronics include a plurality of time-to-digital converters configured to receive signal...
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7105808 |
Plasma ion mobility spectrometer
Ion mobility spectrometer. The spectrometer includes an enclosure for receiving a sample therewithin and an electron beam window admits an electron beam into the enclosure to ionize the sample in...
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7105807 |
Multi dynode device and hybrid detector apparatus for mass spectrometry
A multi dynode device (MDD) for electron multiplication and detection and a hybrid detector using the MDD have high peak signal output currents and large dynamic range while preserving the...
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7098449 |
Spectrometer chip assembly
Method and apparatus for high field asymmetric waveform ion mobility spectrometry in an electronic chip assembly,, including an input section, an ion filter and detection section and a control...
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7095015 |
Mass spectrometer
A mass spectrometer is disclosed wherein the pusher electrode of a Time of Flight mass analyser is operated in conjunction with an ion gate to ensure that low mass background or matrix ions are not...
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7095013 |
Mass spectrometer
A mass spectrometer is disclosed having an ion guide which receives ions from either a pulsed ion source or an ion trap, or a continuous ion source. The ion guide emits packets of ions. The pulses...
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7091479 |
Threat identification in time of flight mass spectrometry using maximum likelihood
A method for determining a threat substance encountered by a time-of-flight mass spectrometer (TOF-MS) using a pre-computed threat library is described. The method comprising the steps of acquiring...
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7091480 |
Method of determining mass-to-charge ratio of ions and mass spectrometer using the method
In an analysis using a mass spectrometer having a loop orbit along which ions are made to fly a plurality of times, the present invention provides a method of determining the mass-to-charge ratio...
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7084406 |
Detector arrangement and detection method
A detector arrangement for detecting position information contained in a beam ( 5 ) of charged particles is provided, comprising a plurality of position-sensitive detectors ( 17 ), each for...
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7084395 |
Time-of-flight mass spectrometer for monitoring of fast processes
Time-of-flight mass spectrometer instruments for monitoring fast processes using an interleaved timing scheme and a position sensitive detector are described. The combination of both methods is...
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7081619 |
Nanodosimeter based on single ion detection
A nanodosimeter device ( 15 ) for detecting positive ions induced in a sensitive gas volume by a radiation field of primary particle, comprising an ionization chamber ( 10 ) for holding the...
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7081618 |
Use of conductive glass tubes to create electric fields in ion mobility spectrometers
An ion mobility spectrometer is described in which the reaction-ionization chamber and/or the ion drift chamber are constructed with one or more single-piece glass tubes. The inner surface of the...
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7078680 |
Ion mobility spectrometer using ion beam modulation and wavelet decomposition
The present invention is directed to a system and a method for analyzing and identifying an unknown sample using ion mobility spectrometry. The method pulses an ion gate using a temporally spaced...
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7078679 |
Inductive detection for mass spectrometry
The invention provides devices, device configurations and methods for improved sensitivity, resolution and efficiency in mass spectrometry, particularly as applied to biological molecules,...
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7075065 |
Time of flight mass spectrometry apparatus
Mass spectrometry apparatus 105 comprises a serial arrangement of an ion source 110 , first time of flight means, a field free region 120 , means to fragment the molecules, a second time of...
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7071003 |
Surface-enhanced laser desorption/Ionization for desorption and detection of analytes
This invention is directed to probes that are removably insertable into mass spectrometers. The probes have sample presenting surfaces, at least, that contain non-metallic materials. The probes are...
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7071466 |
Mass spectrometry system for continuous control of environment
A mass spectrometry system for continuous control of environment based on the use of an aerosol TOF MS that provides operation with a high duty cycle of up to 98% and can be realized in the form of...
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7071463 |
Calibration method
In its most general terms the invention compensates for the effect of the mass offset in the prior art calibration method. This can be achieved either by correcting for the offset or assigning mass...
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7067804 |
Atmospheric pressure ion lens for generating a larger and more stable ion flux
An ion lens is used to focus ions produced by various types of ion sources which are substantially at atmospheric pressure. The ions are focused to the inlet of a downstream mass spectrometer or...
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7067828 |
Method of and apparatus for measurement and control of a gas cluster ion beam
Methods and apparatus are disclosed for measuring controlling characteristics of clusters in a cluster ion beam, including average cluster ion velocity {overscore (v)}, average cluster ion mass...
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7067800 |
Method for measuring the concentration of impurities in nitrogen, hydrogen and oxygen by ion mobility spectrometry
A method for the quantitative analysis of the impurities content in nitrogen, hydrogen or oxygen by means of ion mobility spectrometry is described. The method involves using pure argon or a...
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7067802 |
Generation of combination of RF and axial DC electric fields in an RF-only multipole
An RF-only multipole includes a spiral resistive path formed around each multipole rod body. RF voltages are applied to the rod body and resistive path, and DC voltages are applied to the resistive...
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7067803 |
Gating device and driver for modulation of charged particle beams
By connecting the Bradbury-Nielson gate (BNG) directly to a driver without a transmission line, distortion of the voltage waveform experienced a the BNG are much reduced. Because the magnitude of...
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7064318 |
Methods and apparatus for aligning ion optics in a mass spectrometer
Methods and apparatus, including computer program products, mass spectrometry systems, and sample plates for use in such systems, implement techniques for calibrating an ion source that includes a...
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7060973 |
Multi-anode detector with increased dynamic range for time-of-flight mass spectrometers with counting data acquisition
A new detection scheme for time-of-flight mass spectrometers is disclosed. This detection scheme allows extending the dynamic range of spectrometers operating with a counting technique (TDC). The...
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7060987 |
Electron ionization source for othogonal acceleration time-of-flight mass spectrometry
A radio-frequency quadrupole ion guide having a symmetrical magnetic field disposed along an axis of the ion guide, wherein the system provides prolonged interaction between electrons and uncharged...
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7053367 |
Mass spectrometer
In a mass spectrometer utilizing an atmospheric pressure ion source, the amount of un-vaporized droplets that reach a mass spectrometric section is reduced. A mass spectrometer comprises: an...
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7052525 |
Vehicle integrated protective system
A protective system having an upstream detection subsystem to detect a contaminant in an airflow and to provide a contaminant signal, an upstream detection subsystem, a filtration subsystem to...
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RE39099 |
Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
A method and apparatus are provided for providing an ion transmission device or interface between an ion source and a spectrometer. The ion transmission device can include a multipole rod set and...
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7046357 |
Apparatus for microfluidic processing and reading of biochip arrays
A method and a device for detecting an analyte, including a substrate having a chemically selective surface; and a fluidic system disposed on the substrate, the manifold having at least one fluid...
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7045777 |
Combined chemical/biological agent mass spectrometer detector
A mass spectrometer including an ion source, a detector, a first end cap electrode arranged proximate to the ion source, a second end cap electrode arranged proximate the detector, and a ring...
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7045776 |
System for collection of data and identification of unknown ion species in an electric field
An apparatus for identification of chemical species by measurement of mobility as a function of high electric field and for generating unique compound-dependent signatures based on ion mobility at...
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7041970 |
Ion optics system for TOF mass spectrometer
A time of flight (TOF) mass spectrometer includes an ion source which has an extraction lens. The extraction lens has an element with an aperture. The aperture extends through the element to form a...
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7038197 |
Mass spectrometer and method of mass spectrometry
A mass spectrometer is disclosed wherein a z-lens upstream of an orthogonal acceleration Time of Flight mass analyser is repeatedly switched between a first mode wherein ions are transmitted to the...
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7034287 |
Mass spectrometer and method of use
Disclosed is a mass spectrometer combining an ion trap and a TOFMS non-coaxially, wherein ion trapping efficiency, mass resolution, and CID efficiency can be maximized. The present invention...
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7034286 |
FAIMS apparatus having plural ion inlets and method therefore
An apparatus for multiplexing ions from a plurality of ionization sources includes a FAIMS analyzer including an inner electrode and an outer electrode, the outer electrode having a plurality of...
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7034288 |
Time-of-flight mass spectrometer
A time-of-flight mass spectrometer capable of cutting out a major portion of carrier gas-derived ions ahead of the ion reservoir. The ion source is of the electron impact type and has source...
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7030372 |
Micromachined field asymmetric ion mobility filter and detection system
A micromechanical field asymmetric ion mobility filter for a detection system includes a pair of spaced substrates defining between them a flow path between a sample inlet and an outlet; an ion...
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