|
Match
|
Document |
Document Title |
|
|
7385187 |
Multi-reflecting time-of-flight mass spectrometer and method of use
A multiple reflecting time-of-flight mass spectrometer (MR-TOF MS) and method of analysis are disclosed. The flight path of ions is folded along a trajectory by electrostatic mirrors. The longer...
|
|
|
7385186 |
Methods of operating ion optics for mass spectrometry
In various embodiments, provided are methods for focusing ions for an ion fragmentor, and methods for operating an ion optics assembly. In various embodiments, the present teachings provide methods...
|
|
|
7381945 |
Non-linear time-of-flight mass spectrometer
A time-of-flight mass spectrometer has a first electrode, a second electrode spaced apart from the first electrode, a third electrode arranged between the first and second electrodes. The third...
|
|
|
7381373 |
System and method for preparative mass spectrometry
A preparative mass spectrometer system includes an ionizer which converts the mixture into gas phase ions of the molecules in the mixture, and a separator which separates the ions according to...
|
|
|
7378651 |
High field asymmetric waveform ion mobility spectrometer FAIMS
Disclosed is an apparatus for separating ions including a plurality of first electrode portions, each first electrode portion of the plurality of first electrode portions having a first length and...
|
|
|
7378650 |
Ion-mobility spectrometer and ion-mobility analysis method
There is provided an ion-mobility spectrometer. This apparatus includes the following configuration components: An ion source for generating first ions, a first drift unit for separating the first...
|
|
|
7378652 |
Nebulizer with plasma source
A combination electrospray/microwave induced plasma (MIP) ionization source is used as the ionization source for a mass spectrometer. The electrospray can be operated in positive mode, negative...
|
|
|
7378649 |
Simplex optimization methods for instrumentation tuning
In some embodiments, a method of optimizing operating parameters of an analytical instrument (e.g. lens voltages of a mass spectrometer) includes steps taken to minimize the method duration in the...
|
|
|
7375317 |
Ion drift-chemical ionization mass spectrometry
A method and apparatus for conducting mass spectrometry. The mass spectrometry may be accomplished by ion drift-chemical ionization mass spectrometry. One embodiment includes a chemical ionization...
|
|
|
7375318 |
Mass spectrometer
An object of the present invention is to provide a mass spectrometer that uses a time-of-flight mass spectrometer for performing mass spectrometry on the basis of the difference in flight time...
|
|
|
7375569 |
Last stage synchronizer system
A pulse jitter reduction circuit employs a low jitter system clock coupled to synchronize a pulse generating device and an ultra low jitter flip-flop to generate substantially jitter-free trigger...
|
|
|
7372020 |
Ion counter
Ions in a steady flow sample are counted by colliding the ions in a mixing chamber with a numerical excess of uncharged or neutral aerosol particles, suitably glycerol, entrained in air, to...
|
|
|
7372022 |
Multipath data acquisition system and method
Improved data acquisition systems and methods that enable large numbers of data samples to be accumulated rapidly with low noise are described. In one aspect, a data acquisition system includes an...
|
|
|
7372021 |
Time-of-flight mass spectrometer combining fields non-linear in time and space
A time-of-flight mass spectrometer which has an iron source, an evacuated tube proximate the ion source and adapted to receive ions from the ion source, and a detector disposed at an end of the...
|
|
|
7368708 |
Apparatus for producing ions from an electrospray assembly
The present invention relates to an apparatus for producing ions from an electrospray assembly. The apparatus comprises an ionization chamber, an electrospray assembly, an isolating electrode, an...
|
|
|
7365317 |
RF surfaces and RF ion guides
Apparatus and methods are provided for trapping, manipulation and transferring ions along RF and DC potential surfaces and through RF ion guides. Potential wells are formed near RF-field generating...
|
|
|
7365316 |
Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry
Method and apparatus for chromatographic high field asymmetric waveform ion mobility spectrometry, including a gas chromatographic analyzer section intimately coupled with an ionization section, an...
|
|
|
7365313 |
Fast time-of-flight mass spectrometer with improved data acquisition system
Time-of-flight mass spectrometer instruments are disclosed for monitoring fast processes with large dynamic range using a multi-threshold TDC data acquisition method or a threshold ADC data...
|
|
|
7365314 |
Single-particle mass spectrometer
Disclosed is a single-particle mass spectrometer, which includes a chamber keeping an inside in a vacuum state by a vacuum pump, a cylindrical flying tube installed to communicate with the chamber,...
|
|
|
7361311 |
System and method for the preparation of arrays of biological or other molecules
A method of separating species in a mixture of molecules, particles or atoms and collecting the separated species is described. The method comprises the steps of converting by ionization the...
|
|
|
7358593 |
Microfabricated miniature grids
A grid structure and method for manufacturing the same. The grid is used for gating a stream of charged particles in certain types of particle measurement instruments, such as ion mobility...
|
|
|
7358487 |
Ion gate
An ion gate is disposed between a first volume occupied by a first carrier gas and ions of the first carrier gas and a second volume occupied by a second carrier gas. The ion gate includes at least...
|
|
|
7351959 |
Mass analyzer systems and methods for their operation
The present teachings relate to MALDI-TOF instruments, instrument components, and methods of operation thereof. In various aspects, the MALDI-TOF instrument can serve and be operated as a MS/MS...
|
|
|
7351958 |
Ion optics systems
In various embodiments, provided are ion optics systems comprising an even number of ion mirrors arranged in pairs such that a trajectory of an ion exiting the ion optics system can be provided...
|
|
|
7345276 |
Ion mobility system comprising two IMS cells operated at different polarities
An ion mobility spectrometer system includes two cells ( 1 ) and ( 2 ) driven by a drive unit ( 12 ) so that the cells operate at opposite polarities and are switched between different polarities...
|
|
|
7339164 |
Systems and methods for ion mobility control
The invention provides, in various embodiments, systems and methods relating to controlling ion behavior in an ion-based analysis system.
|
|
|
7339165 |
Dual outlet pyrolyzer for biological agent detection system
A chemical biological detection system detects the presence of biological agents in the air. The system includes a pyrolyzer having an inlet through which air is drawn into the pyrolyzer and a...
|
|
|
7332713 |
Mass spectrometric method and mass spectrometric system
In a method for mass spectrometry, a plurality of juxtaposed chromatography apparatus connected to a mass spectrometer start eluting at a predetermined time difference and the following mass...
|
|
|
7323344 |
Method of measuring the concentration of hydrogen and methane in nitrogen by ion mobility spectrometry
A method is provided for the quantitative analysis of the contents, in nitrogen, of hydrogen and methane by ionic mobility spectrometry. The method includes the steps of: a) performing a...
|
|
|
7321116 |
Ionization source for mass spectrometer
An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without...
|
|
|
7317187 |
Frontal affinity chromatography/MALDI tandem mass spectrometry
Sol-gel derived monolithic silica columns containing entrapped dihydrofolate reductase were used for frontal affinity chromatography of small molecule mixtures. The output from the column combined...
|
|
|
7312442 |
Enhanced gradient multipole collision cell for higher duty cycle
A method for processing ions in mass spectrometry is provided. The method provides for processing ions in a ion processing cell having elongated segmented rods, a circuit for applying RF voltages...
|
|
|
7312443 |
Reflectron
A reflectron ( 109 ) is provided with at least two sets of field resistances ( 131 a - 131 n, 137 a - 137 n ) which may be connected together or separately to the reflectron electrodes ( 123 a -...
|
|
|
7304298 |
Photoemissive ion mobility spectrometry in ambient air
A photoemissive ion mobility spectrometer is disclosed for of chlorinated hydrocarbons and nitro-organic materials. Backside illumination of a thin gold film by pulsed laser radiation, pulsed...
|
|
|
7301145 |
Daughter ion spectra with time-of-flight mass spectrometers
The invention relates to methods and devices for measuring daughter ion spectra (also called fragment ion spectra or MS/MS spectra) in time-of-flight mass spectrometers with orthogonal injection of...
|
|
|
7294830 |
Simultaneous acquisition of chemical information
A method and apparatus for operating a mass spectrometer include providing at least two different ion sources, and coupling ion streams simultaneously from the at least two different ion sources to...
|
|
|
7291834 |
Multi-anode detector with increased dynamic range for time-of-flight mass spectrometers with counting data acquisitions
A detection scheme for time-of-flight mass spectrometers is described that extends the dynamic range of spectrometers that use counting techniques while avoiding the problems of crosstalk. It is...
|
|
|
7285774 |
FAIMS apparatus and method for separating ions in the gas phase
Disclosed is a high field asymmetric waveform ion mobility spectrometer (FAIMS) including a set of spaced-apart parallel rods, the space between the parallel rods having first and second ends and...
|
|
|
7277799 |
Isotope correlation filter for mass spectrometry
The present invention relates generally to mass spectrometry and the analysis of chemical samples, and more particularly to methods for processing data obtained therefrom. Disclosed is an improved...
|
|
|
7276688 |
Ion-optical phase volume compression
The invention relates to a method for damping the kinetic energy of ions in ion cells filled with collision gas and with an exit aperture to drain the ions out of the cell. The invention uses a...
|
|
|
7276712 |
Method and apparatus for scanning a workpiece in a vacuum chamber of an ion beam implanter
An ion beam implanter includes an ion beam source for generating an ion beam moving along a beam line and an implantation chamber wherein a workpiece is positioned to intersect the ion beam for ion...
|
|
|
7268347 |
Ion detecting apparatus and methods
Ion injection in a drift tube apparatus for mobility spectrometry was accomplished without conventional ion shutters such as the Bradbury-Nielson or similar designs common to such drift tubes....
|
|
|
7265368 |
Ion optical mounting assemblies
In various embodiments, provided are ion optical assemblies, and systems for mounting and aligning ion optic components. In various embodiments, the present teachings provide ion optical assemblies...
|
|
|
7265347 |
Multiple nano-spray delivery system for FAIMS
An apparatus for multiple nano-spray delivery of a sample to FAIMS analyzer includes a micro-machined ionization source having a plurality of discrete nozzles. At least some of the discrete nozzles...
|
|
|
7265346 |
Multiple detection systems
A particle detection system is configured and operated as two or more separate and completely independent detection systems. The detection systems may be of the same or different design, may be...
|
|
|
7262407 |
Explosives detection using differential mobility spectrometry
The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems, methods, and devices...
|
|
|
7259369 |
Dual mode ion mobility spectrometer and method for ion mobility spectrometry
Ion mobility spectrometer apparatus may include an ion interface that is operable to hold positive and negative ions and to simultaneously release positive and negative ions through respective...
|
|
|
7260483 |
Real-time detection method and system for identifying individual aerosol particles
An improved method and system of identifying individual aerosol particles in real time. Sample aerosol particles are collimated, tracked, and screened to determine which ones qualify for mass...
|
|
|
7259368 |
Apparatus for delivering ions from a grounded electrospray assembly to a vacuum chamber
The present invention relates to an apparatus for delivering ions to a vacuum chamber. The apparatus comprises an ionization chamber, an ionization region within the ionization chamber, a vacuum...
|
|
|
7256393 |
Non-linear signal amplifiers and uses thereof in a mass spectrometer device
Signal amplifiers having a non-linear transfer function. A high speed (high bandwidth) circuit with a non-linear transfer function over a limited range of input signal is provided. By appropriate...
|