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7619217 |
High power laser induced acoustic desorption probe
A high power laser-induced acoustic desorption (LIAD) probe is provided for desorbing neutral molecules from a sample analyte on a target into a mass spectrometer for subsequent ionization.
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7619214 |
Spectrometer chip assembly
Method and apparatus for high field asymmetric waveform ion mobility spectrometry in an electronic chip assembly, including an input section, an ion filter and detection section and a control...
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7619213 |
Ion extraction pulser and method for mass spectrometry
The invention provides an ion extraction pulser. The ion extraction pulser may be used independently or in conjunction with a mass spectrometry system. The mass spectrometry system includes an ion...
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7619212 |
Chromatographic analyzer
When a standard specimen including a given reference component is analyzed after a separation condition is changed, a data processing section ( 31 ) acquires an actual measurement value of a peak...
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7615743 |
Overcoming space charge effects in ion cyclotron resonance mass spectrometers
In an ion cyclotron resonance mass spectrometer in which ions are trapped axially by applying electrical potentials to a pattern of electrode elements to produce an inhomogeneous alternating...
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7615742 |
Measurement of light fragment ions with ion traps
The invention relates to methods for the measurement of fragment ion spectra in ion trap mass spectrometers in which fragment ions below a cut-off mass cannot normally be measured. The invention...
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7612335 |
Method and apparatus for ion fragmentation by electron capture
The present invention relates to a method and apparatus for ion fragmentation by electron capture. The present invention provides a method of generating fragment ions by electron capture,...
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7608819 |
Mass spectrometer
The present invention provides a mass spectrometry capable of high-efficiency and high-throughput ECD. An electron source and a two-dimensional combined ion trap in which a magnetic field along and...
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7608818 |
Compact gas chromatography and ion mobility based sample analysis systems, methods, and devices
A compact integrated ion mobility based analysis system includes at least one gas chromatograph (GC) column that receives a sample and elutes constituents of the sample where each of the eluted...
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7608817 |
Adiabatically-tuned linear ion trap with fourier transform mass spectrometry with reduced packet coalescence
A linear ion trap traps a plurality of charged particles in a charged particle trap including first and second electrode mirrors arranged along an axis at opposite ends of the particle trap, the...
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7605377 |
On-chip reflectron and ion optics
A microelectronics apparatus comprising a substrate, a pair of grid electrodes coupled to the substrate on opposing sides of a central axis, wherein the grid electrodes are substantially parallel...
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7605367 |
Explosives detection using differential mobility spectrometry
The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems, methods, and devices...
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7601952 |
Method of operating a mass spectrometer to provide resonant excitation ion transfer
A method of operating a mass spectrometer having a rod set is provided. The rod set has a first end, a second end opposite to the first end, and a longitudinal axis extending between the first end...
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7598489 |
Systems and methods for ion mobility control
The invention provides, in various embodiments, systems and methods relating to controlling ion behavior in an ion-based analysis system.
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7598488 |
Apparatus and method for field asymmetric ion mobility spectrometry combined with mass spectrometry
In a system for analyzing samples by mass spectrometry, analyte ions are analyzed first by field asymmetric ion mobility spectrometry (FAIMS) before being analyzed by a mass analyzer. The analyte...
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7598487 |
Micro-hydrocarbon analysis
The present invention is a method to determine the composition of a hydrocarbon feedstream from a small sample of hydrocarbons including the steps analyzing the sample with a combination of...
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7598486 |
Sample plate for glycoprotein analysis by MALDI mass spectrometry and preparation method of the same
The present invention relates to a sample plate for matrix-assisted laser desorption ionization (MALDI) mass spectrometry having a stable glyco-affinity layer of a carboxyalkyl boronic acid or...
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7595486 |
RF multipole ion guides for broad mass range
In a multipole rod ion guide system operated with RF voltages to collect or transmit ions, the inhomogeneity of the electric RF fields is increased in front of the ion guide rods by forming the rod...
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7595485 |
Data analysis to provide a revised data set for use in peptide sequencing determination
In one aspect of the present invention, the less “useful” spectral data is disregarded from the spectral data resulting from the fragmentation by ETD and candidate charge states for the...
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7595484 |
Mass spectrometric method, mass spectrometric system, diagnosis system, inspection system, and mass spectrometric program
The present invention can provide a mass spectrometric system judging whether a measurement target is a substance required by an operator within an actual measurement time, when a substance...
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7593817 |
Calculating confidence levels for peptide and protein identification
Computer programs and methods for defining a misidentification probability for an experimental protein divisible into experimental peptides. The invention receives data representing a set of...
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7589320 |
Mass spectrometer
An electron capture dissociation device to implement a combination of electron capture dissociation and collision dissociation and a mass spectrometer with the use thereof are provided. This device...
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7589319 |
Reflector TOF with high resolution and mass accuracy for peptides and small molecules
Many applications in the study of metabolics and proteomics require measurements on peptides and small molecules with high resolving power and mass accuracy. These are often present in complex...
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7589318 |
Mass defect triggered information dependent acquisition
Systems and methods for analyzing compounds in a sample. In one embodiment, a mass spectrometer includes an ion source for emitting a plurality of ions from a sample together with a detector...
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7588944 |
Method of analyzing C-terminal amino acid sequence of peptide
An analyte peptide is selectively degraded sequentially by using an alkanoic anhydride (S 101 ). The original peptide and a series of degradation reaction products having peptide in which one or...
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7586111 |
Ion implanter having combined hybrid and double mechanical scan architecture
A system and method are provided for implanting ions into a workpiece in a plurality of operating ranges. A desired dosage of ions is provided, and a spot ion beam is formed from an ion source and...
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7586092 |
Method and device for non-contact sampling and detection
A system for the stand-off detection of trace amounts of analyte materials such as explosives, chemical warfare agents, toxic industrial chemicals, and the like includes an ion source that is...
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7586091 |
Mass spectrometric system and mass spectrometry
After a sample is previously separated into plural components in a channel formed in a microchip ( 353 ), the channel is irradiated along a separation direction with a laser beam from a laser...
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7586090 |
Cell structure, device and method for gas analysis
The invention relates to a gas analysis based on the mobility of ions. The invention relates to a cell structure of an analysis device, the cell structure comprising the reference cell ( 201 ), the...
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7586089 |
Feedback fragmentation in ion trap mass spectrometers
In an RF ion trap mass spectrometer, selected parent ions are fragmented by collisions or electrons and a spectrum of the ion fragments is measured. The measured fragment ion spectrum is then...
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7583710 |
Laser and environmental monitoring system
A laser and monitoring system is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present invention...
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7582866 |
Ion trap mass spectrometry
Disclosed is an ion trap mass spectrometer for MS n analysis, which comprises a frequency-driven ion trap section operable to trap sample ions and isolate a precursor ion from the sample ions,...
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7582865 |
Two-dimensional ion trap with ramped axial potentials
The invention provides a two-dimensional ion trap, comprising a plurality of elongate electrodes positioned between first and second end electrodes, the plurality of electrodes and first and second...
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7582864 |
Linear ion trap with an imbalanced radio frequency field
An imbalanced radio frequency (RF) field creates a retarding barrier near the exit aperture of a multipole ion guide, in combination with the extracting DC field such that the barrier provides an...
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7582862 |
Ion source for electron transfer dissociation and deprotonation
In mass spectrometric analysis equipment, highly charged analyte fragment ions are obtained by electron transfer dissociation of highly charged analyte ions by radical anions and the dissociation...
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7579589 |
Ultra compact ion mobility based analyzer apparatus, method, and system
An ultra compact ion mobility based analyzer in a multilayered chip assembly employing various features such as a ion flow generator to propel ions through an ion mobility based filter and,...
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7579587 |
Thermally assisted membrane introduction mass spectrometry (MIMS) interface and method of use thereof
A membrane introduction mass spectrometry (MIMS) sampling interface is presented that demonstrates improved online performance for the direct, real-time measurement of semi-volatile organic...
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7579586 |
Ion selector
The present invention provides an ion selector gate having a first deflection zone 32 and a second deflection zone 34 spaced from the first deflection zone, wherein in use, a single low voltage...
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7579585 |
Method and apparatus for scanning an ion trap mass spectrometer
A mass spectrometer system having an ion trap and a downstream mass spectrometer is provided. A plurality of groups of ions are provided to the ion trap and a first mass-to-charge ratio is...
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7577538 |
Computational method and system for mass spectral analysis
A method for analyzing data from a mass spectrometer including obtaining calibrated mass spectral data involving at least one ion with its isotopes, by processing raw spectral data; obtaining...
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7576324 |
Ion detection methods, mass spectrometry analysis methods, and mass spectrometry instrument circuitry
Ion detection methods are provided that can include applying a first voltage between a power source and a dynode, and contacting the dynode with first ions to create a first charged species. After...
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7576323 |
Point-of-care mass spectrometer system
A point-of-care mass spectrometer system has a sampling system, an ionization component structured to receive a sample for analysis from the sampling system, a mass analyzer structured to receive a...
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7576321 |
Multidimensional ion mobility spectrometry apparatus and methods
Various embodiments of a multi-dimensional ion mobility analyzer are disclosed that have more than one drift chamber and can acquire multi-dimensional ion mobility profiles of substances. The drift...
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7576319 |
Systems for differential ion mobility analysis
Disclosed herein are systems, methods and apparatus, for detection and identification of chemical warfare agents (CWAs) using a differential mobility spectrometer.
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7576318 |
Method and apparatus for mass spectrometry
The present invention relates to mass spectrometry and, more particularly, to the scheduling of the steps involved in performing mass spectrometry. The present invention will be of particular...
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7573029 |
Ion trap with longitudinal permanent magnet and mass spectrometer using same
A vacuum magnetic ion trap includes an assembly forming a permanent magnet including at least two magnetized structures ( 30, 32 ) in the form of hollow cylinders, one convergent radial structure,...
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7569815 |
GC mass spectrometry interface and method
The invention provides a GC mass spectrometry system, including a column for introducing a sample into the GC mass spectrometry system, a heating source for providing heat to the sample to be...
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7569814 |
Mass spectrometer
A mass spectrometer includes: an ion source for ionizing a specimen to generate ions, an ion transport portion for transporting the ions, a linear ion trap portion for accumulating the transported...
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7569813 |
Method for enhancing mass assignment accuracy
A method of operating an ion trap spectrometer system having an ion trap is provided. The method comprises a) providing a group of ions for analysis, wherein the group of ions includes a first...
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7569812 |
Remote reagent ion generator
An improved ion source and means for collecting and focusing dispersed gas-phase ions from a remote reagent chemical ionization source (R2CIS) at atmospheric or intermediate pressure is described....
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