|
Match
|
Document |
Document Title |
|
|
7417225 |
Apparatus and method for adjustment of ion separation resolution in FAIMS
An apparatus for separating ions includes a FAIMS analyzer region having a first ion inlet for introducing ions into the FAIMS analyzer region. An ion outlet from the FAIMS analyzer region is...
|
|
|
7418352 |
Method of using data binning in the analysis of chromatography/spectrometry data
Disclosed herein is a method of analyzing three-dimensional data obtained from a chromatography/spectrometry process, in particular an LC/MS process using a two-dimensional multi-variant...
|
|
|
7417223 |
Method, system and computer software product for specific identification of reaction pairs associated by specific neutral differences
A first mass spectrum and a second mass spectrum of the same ion sample can be analyzed to determine reaction pairs. These reaction pairs are determined based on a selected neutral difference by...
|
|
|
7417226 |
Mass spectrometer
An Atmospheric Pressure Chemical Ionisation (“APCI”) ion source is disclosed comprising a housing 14 having a corona discharge chamber 1 , a reaction chamber 2 and a passage 6 connecting...
|
|
|
7414242 |
Ion mobility spectrometry method and apparatus
The invention includes an ion mobility spectrometer having a liquid filled drift chamber. The chamber has an ionization region partitioned from and an ion separation region by a reversible...
|
|
|
7412334 |
Mass spectrometer and method for enhancing resolution of mass spectra
A mass spectrometer comprises an ion detector, an analog-to-digital (A/D) converter, a sample adjuster, and an adder. The A/D converter is configured to receive and sample an analog signal from the...
|
|
|
7411185 |
Atmospheric pressure ionization mass spectrometer system
An atmospheric pressure ionization mass spectrometry system has an atmospheric pressure ionization chamber for ionizing a sample, an evacuated intermediate evacuation chamber into which generated...
|
|
|
7411187 |
Ion trap in a semiconductor chip
A micrometer-scale ion trap, fabricated on a monolithic chip using semiconductor micro-electromechanical systems (MEMS) technology. A single 111Cd+ ion is confined, laser cooled, and the heating...
|
|
|
7411186 |
Multimode ion source with improved ionization
A multimode ionization source with improved ionization characteristics that comprises an electrospray ionization source for providing a charged aerosol, an atmospheric pressure chemical ionization...
|
|
|
7408147 |
Nanoelectromechanical and microelectromechanical sensors and analyzers
The present invention provides methods, devices and device components for detecting, sensing and analyzing molecules. Detectors of the present invention provide good detection sensitivity over a...
|
|
|
7408152 |
Ion source using matrix-assisted laser desorption/ionization
An ion source generating ions by matrix-assisted laser desorption/ionization (MALDI) comprising a MALDI sample support and a solid-state the laser system generating a pulsed laser beam, which has a...
|
|
|
7405399 |
Field conditions for ion excitation in linear ion processing apparatus
Methods for applying an RF field in a two-dimensional electrode structure include applying RF voltages to main electrodes and to compensation electrodes. The voltages on the compensation electrodes...
|
|
|
7405401 |
Ion extraction devices, mass spectrometer devices, and methods of selectively extracting ions and performing mass spectrometry
There is disclosed a method of selectively extracting ions comprising the steps of: providing a supply of ions in a body of gas; generating a ponderomotive ion trapping potential generally along...
|
|
|
7405410 |
Method and apparatus for confining, neutralizing, compressing and accelerating an ion field
An apparatus and method of use for injection, confinement, neutralization, acceleration and compression of an ion field using a solenoid having an axis of symmetry and supported within a vacuum...
|
|
|
7405400 |
Adjusting field conditions in linear ion processing apparatus for different modes of operation
Methods for applying an RF field in a two-dimensional electrode structure include applying RF voltages to one or more main electrodes and compensation electrodes. The voltages on the one or more...
|
|
|
7405397 |
Laser desorption ion source with ion guide coupling for ion mass spectroscopy
A laser desorption ion source provides enhanced ion sampling efficiency and measurement sensitivity by using one or more ion guides to effectively capture ions in a plume emitted from the ion...
|
|
|
7405398 |
Mass spectrometer interface
A mass spectrometer interface, having improved sensitivity and reduced chemical background, is disclosed. The mass spectrometer interface provides improved desolvation, chemical selectivity and ion...
|
|
|
7402816 |
Electron injection in ion implanter magnets
One or more electron sources are utilized to inject electrons into an ion beam being transported between the polepieces of a magnet. In some embodiments, the electron sources are located in...
|
|
|
7402799 |
MEMS mass spectrometer
A MEMS mass spectrometer having metal walls connected between a lid and base, with the walls defining a plurality of interior chambers including sample gas input chambers, an ionizer chamber, a...
|
|
|
7399959 |
Method and apparatus for enhanced ion based sample filtering and detection
The invention provides, in various embodiments, systems and methods relating to enhancing the filtering and detection capability of ion mobility based systems by various techniques to counteract a...
|
|
|
7399957 |
Coded mass spectroscopy methods, devices, systems and computer program products
A coded mass spectrometer incorporates a spatial or temporal code to reduce the resolution/sensitivity dichotomy inherent in mass spectrometry. The code is used to code one or more portions of a...
|
|
|
7399958 |
Method and apparatus for enhanced ion mobility based sample analysis using various analyzer configurations
A system for analyzing one or more ion species of a sample including a first ion mobility filter associated with a first flow path for passing first ions of the sample, a second ion mobility filter...
|
|
|
7399961 |
High throughput ion source with multiple ion sprayers and ion lenses
An apparatus with means for controlling ion generation is discussed. The apparatus comprises a plurality of ion sources, at least one counter electrode mounted downstream for the ion sources and at...
|
|
|
7397026 |
Efficient electron transfer dissociation for mass spectrometry
The present invention relates to, inter alia, methods and apparatuses for electron transfer dissociation (ETD) that vary the internal energy of precursor ions for ETD. The methods and apparatuses...
|
|
|
7397028 |
Apparatus and method for gas flow management
The invention described herein provides a mass spectrometry system, having an ion source including an ionization device for producing ions, a collection conduit adjacent to the ionization device...
|
|
|
7397027 |
Multi-channel high-field asymmetric waveform ion mobility spectrometry
A multi-channel high field asymmetric waveform ion mobility spectrometer (FAIMS) is provided. The apparatus provides for substantially simultaneous FAIMS analysis of plurality of ions from a single...
|
|
|
7391020 |
Electrospray apparatus with an integrated electrode
The invention provides related apparatus and methods of making an integrated electrospray tip by depositing ionic and/or electronic conductor materials onto a planar substrate. The invention also...
|
|
|
7391019 |
Electrospray ion source
An on-axis ion source has an ionization chamber and an adjacent low-pressure region. The on-axis ion source also includes a capillary tube having an axial bore for supporting fluid communication...
|
|
|
7391017 |
Mass scale alignment of time-of-flight mass spectra
The invention generates mass scale comparability between mass spectra which are acquired in time-of-flight mass spectrometers, particularly with ionization by matrix-assisted laser desorption....
|
|
|
7391015 |
System and method for data collection in recursive mass analysis
Systems, methods, and computer programming for collecting data using a mass spectrometer comprising a particle detector or other mass analyzer. A data collection such as a tree or array structure...
|
|
|
7391021 |
Ion guides with RF diaphragm stacks
The invention relates to RF voltage-operated ion guides based on stacked apertured diaphragms. The invention provides ion guides consisting of diaphragm stacks that permit the ion beam to be shaped...
|
|
|
7388197 |
Multiplex data acquisition modes for ion mobility-mass spectrometry
A method and apparatus for multiplexed data acquisition for gas-phase ion mobility coupled with mass spectrometry is described. Ion packets are injected into an ion mobility drift chamber at a rate...
|
|
|
7388195 |
Apparatus and systems for processing samples for analysis via ion mobility spectrometry
The invention provides an interface assembly for delivering an ionized analyte from an ionization apparatus into an ion mobility spectrometer. This allows analysis of biological and non-biological...
|
|
|
7388196 |
Hyperbolic horn helical mass spectrometer
An improved rotating electric field ion mass spectrometer (REFIMS) provides for a smooth transition of the input ion beam from zero rotation to the desired level of field rotation. The REFIMS grid...
|
|
|
7388201 |
Radiation detector having coated nanostructure and method
A radiation detector has an electron emitter that includes a coated nanostructure on a support. The nanostructure can include a plurality of nanoneedles. A nanoneedle is a shaft tapering from a...
|
|
|
7388194 |
Method and system for high-throughput quantitation using laser desorption and multiple-reaction-monitoring
A mass spectrometry quantitation technique enables high-throughput quantitation of small molecules using a laser-desorption (e.g., MALDI) ion source coupled to a triple-quadrupole mass analyzer....
|
|
|
7385185 |
Molecular activation for tandem mass spectroscopy
In a tandem mass spectrometer means are provided for molecular activation of ions prior to fragmentation. An embodiment of a tandem mass spectrometer comprises a first collision cell receiving...
|
|
|
7385187 |
Multi-reflecting time-of-flight mass spectrometer and method of use
A multiple reflecting time-of-flight mass spectrometer (MR-TOF MS) and method of analysis are disclosed. The flight path of ions is folded along a trajectory by electrostatic mirrors. The longer...
|
|
|
7385189 |
Nanospray ionization device and method
The present invention provides an apparatus and method for use with a mass spectrometry system. The invention provides an ion source for providing radiative heating to an ionization region. The ion...
|
|
|
7385186 |
Methods of operating ion optics for mass spectrometry
In various embodiments, provided are methods for focusing ions for an ion fragmentor, and methods for operating an ion optics assembly. In various embodiments, the present teachings provide methods...
|
|
|
7385191 |
High pressure membrane introduction for a mass spectrometer
A membrane-introduction mass spectrometer (MIMS) device has a sample inlet assembly provided with a membrane held by an outer retaining ring across the entrance of a central passage, a porous metal...
|
|
|
7381945 |
Non-linear time-of-flight mass spectrometer
A time-of-flight mass spectrometer has a first electrode, a second electrode spaced apart from the first electrode, a third electrode arranged between the first and second electrodes. The third...
|
|
|
7378648 |
High-resolution ion isolation utilizing broadband waveform signals
A desired ion is isolated in an ion trapping volume by applying an ion isolation signal to a plurality of ions in the ion trapping volume, including the desired ion to be retained in the ion...
|
|
|
7378651 |
High field asymmetric waveform ion mobility spectrometer FAIMS
Disclosed is an apparatus for separating ions including a plurality of first electrode portions, each first electrode portion of the plurality of first electrode portions having a first length and...
|
|
|
7378650 |
Ion-mobility spectrometer and ion-mobility analysis method
There is provided an ion-mobility spectrometer. This apparatus includes the following configuration components: An ion source for generating first ions, a first drift unit for separating the first...
|
|
|
7378653 |
Increasing ion kinetic energy along axis of linear ion processing devices
In a method for increasing the kinetic energy of an ion in a linear electrode structure, axial motion of the ion is constrained substantially to a selected axial end the electrode structure. The...
|
|
|
7378652 |
Nebulizer with plasma source
A combination electrospray/microwave induced plasma (MIP) ionization source is used as the ionization source for a mass spectrometer. The electrospray can be operated in positive mode, negative...
|
|
|
7372020 |
Ion counter
Ions in a steady flow sample are counted by colliding the ions in a mixing chamber with a numerical excess of uncharged or neutral aerosol particles, suitably glycerol, entrained in air, to...
|
|
|
7372022 |
Multipath data acquisition system and method
Improved data acquisition systems and methods that enable large numbers of data samples to be accumulated rapidly with low noise are described. In one aspect, a data acquisition system includes an...
|
|
|
7372043 |
Apparatus and method for ion production enhancement
The invention described herein provides a matrix-based ion source including a gas heating device for providing heated gas at a defined temperature to the ionization region of the ion source. The...
|