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7473892 |
Mass spectrometer system
During the structural analysis of a protein or peptide by tandem mass spectroscopy, a peptide ion derived from a protein that has already been measured and that is expressed in great quantities is...
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7473560 |
Steroid hormone analysis by mass spectrometry
Methods, systems and kits for the simultaneous or sequential analysis of a multitude of steroid hormones by mass spectrometry are disclosed. The methods require minimal sample size and minimal...
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7468511 |
FAIMS electrodes with lateral ion focusing
A FAIMS cell including one of side-to-side cylindrical geometry electrodes and stacked-plate electrodes is adapted with a medial surface feature for focusing ions along a lateral direction within...
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7465940 |
Ionization by droplet impact
The invention relates to methods and instruments for ionizing analyte molecules, preferably biomolecules, which are dissolved in liquids or firmly adsorbed on surfaces. Liquids are nebulized at...
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7465919 |
Ion detection system with neutral noise suppression
An ion detection system includes a mass analyzer generating an ion beam along an ion beam longitudinal axis. A field generator generates a field for altering the direction of ions in the ion beam...
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7465921 |
Structured carbon nanotube tray for MALDI plates
An apparatus for producing analyte ions for detection by a mass spectrometer is described. The apparatus includes an ion source in which the surface of a target substrate for holding an analyte...
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7465920 |
Ionization method and apparatus for mass analysis
A laser spray method exhibiting a high detection sensitivity when applied to mass analysis has its sensitivity raised further. In a laser spray method of ionizing a liquid sample by irradiating,...
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7462820 |
Isotope separation process and apparatus therefor
A process and apparatus for separating element isotopes in space by imparting a velocity and direction to a body of material along a substantially linear path, heating and vaporizing the body and...
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7462817 |
Mass spectrometer and method of analyzing isomers
The invention intends to determine a presence ratio between mixed compounds which are difficult to separate from each other by a separation unit and cannot be discriminated by MS. In a mass...
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7462824 |
Combined ambient desorption and ionization source for mass spectrometry
Combined desorption and ionization sources are provided to generate molecular ions form a sample disposed on a substrate surface. A heated gas-jet probe or heated solvent stream probe desorbs...
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7462825 |
Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
A field asymmetric ion mobility spectrometer apparatus and system including a sample preparation and introduction section, a head for delivery of ions from a sample, an ion filtering section, an...
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7462821 |
Instrumentation, articles of manufacture, and analysis methods
Analysis methods are provided that include generating a sample data set using a sample, the sample data set comprising first and second data sets, wherein each of the first and second data sets...
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7459693 |
Ion guide for mass spectrometers
Disclosed is an improved method and apparatus for transporting ions from a first pressure region in a mass spectrometer to a second pressure region therein. More specifically, the present invention...
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7459678 |
Switchable branched ion guide
A switchable branched ion guide is disclosed. The switchable branched ion guide includes a trunk section, first and second branch sections, a junction connecting the trunk section to the branch...
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7456394 |
Compact sample analysis systems and related methods of using combined chromatography and mobility spectrometry techniques
The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems and methods, and...
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7456392 |
Use of ultraphobic surfaces having a multitude of hydrophilic areas for analyzing samples
The invention relates to the use of surfaces having hydrophilic and/or oleophilic areas, each of which being completely surrounded by the ultraphobic areas, for analyzing samples. The invention...
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7456397 |
Ion fragmentation by electron transfer in ion traps
The invention relates to a method and instrument for the fragmentation of large molecular analyte ions, preferably biopolymer ions, by reactions between multiply charged positive analyte ions and...
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7456395 |
Glow discharge source
A glow discharge source, in particular for the analysis of solid specimens by means of glow discharge, with an anode and a cathode and with means for the direct or indirect cooling of a specimen,...
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7456391 |
Gating device and driver for modulation of charged particle beams
By connecting the Bradbury-Nielson gate (BNG) directly to a driver without a transmission line, distortion of the voltage waveform experienced a the BNG are much reduced. Because the magnitude of...
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7456389 |
High throughput quadrupolar ion trap
A method and apparatus are provided for operating a linear ion trap. A linear ion trap configuration is provided that allows for increased versatility in functions compared to a conventional...
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7456388 |
Ion guide for mass spectrometer
An ion guide 24 for a mass spectrometer 30 including means for ejecting ions of different mass-to-charge ratios from the ion guide towards a detector or other object or device. The ejecting...
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7456398 |
Efficient detection for ion traps
An apparatus and method are disclosed for efficient detection of ions ejected from a quadrupolar ion trap, in which the ions are ejected as first and second groups of ions having different...
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7453074 |
Ion implanter with ionization chamber electrode design
An ion implanter includes an ion source for generating an ion beam moving along a beam line and a vacuum or implantation chamber wherein a workpiece, such as a silicon wafer is positioned to...
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7450618 |
Laser system using ultrashort laser pulses
A laser system using ultrashort laser pulses is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present...
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7449687 |
Methods and compositions for combining ions and charged particles
The invention provides an apparatus for combining ions and charged particles. In general, the apparatus contains: a) a multipole device having an ion exit end; b) a mass analyzer; and c) a source...
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7449682 |
System and method for depth profiling and characterization of thin films
Characterization of a sample, e.g., a depth profile, may be attained using one or more of the following parameters in an electron spectroscopy method or system. The one or more parameters may...
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7449685 |
Gas monitoring apparatus
A gas monitoring apparatus includes a sample introducing portion, a measurement portion, an ionization portion, a mass analysis portion, a data processing portion and a display. The sample...
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7449683 |
Method and apparatus for high-order differential mobility separations
The present invention relates generally to separation of ions based on their transport properties. More particularly, the invention relates to separation of ionic mixtures and characterization of...
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7446311 |
Method of coating an electrospray emitter
The present invention provides a method of coating an electrospray emitter with silver and then gold utilizing wet-coating processes. First, the electrospray emitter is immersed in a...
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7446327 |
Apparatus for amplifying a stream of charged particles
Apparatus for amplifying a stream of primary charged particles comprises a body defining a chamber and an entrance aperture for receiving the stream of primary charged particles into the chamber,...
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7446312 |
Generation of multiply charged ions for tandem mass spectrometry
Multiply-charged ions are generated from singly-charged ions of analyte substances. The singly-charged ions, which are supplied by many types of ion sources, are accelerated, together with donor...
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7446309 |
In-plane distribution measurement method
In plane distribution of a target object contained in a sample is measured. The sample dispersedly placed on a substrate is treated to promote ionization of the target object. Then, the mass and...
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7442556 |
Microfluidic-based electrospray source for analytical devices with a rotary fluid flow channel for sample preparation
This invention provides microfluidic devices and methods for using the same. Microfluidic devices of the present invention comprises a first elastic layer, a fluid flow channel within the elastic...
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7442920 |
Optical bench for a mass spectrometer system
Mass spectrometer systems for measuring mass/charge ratios of analytes are described. A mass spectrometer system includes a vacuum flange, a PCB base plate coupled to the vacuum flange, and an ion...
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7435953 |
Quadrupole mass filter length selection
In this invention the technology is provided for rod shaped conductor member fabrication in situ, in position, in the mass filter spatial configuration by growth through vertically repeated conduit...
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7435949 |
Mass spectrometric analysis method and system using the method
A tandem analysis system is provided for ionizing a substance, performing mass spectrometric analysis of various ion types generated, selecting and dissociating an ion type, the ion type having a...
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7435951 |
Ion source sample plate illumination system
The invention provides a mass spectrometry system ion source containing a sample plate and an illumination device that is configured to produce a light beam that contacts the sample plate surface...
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7432516 |
Rapid cycling medical synchrotron and beam delivery system
A medical synchrotron which cycles rapidly in order to accelerate particles for delivery in a beam therapy system. The synchrotron generally includes a radiofrequency (RF) cavity for accelerating...
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7429731 |
Method and device for non-contact sampling and detection
A system for the stand-off detection of trace amounts of analyte materials such as explosives, chemical warfare agents, toxic industrial chemicals, and the like includes an ion source that is...
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7429728 |
Distance of flight spectrometer for MS and simultaneous scanless MS/MS
A distance of flight (DOF) approach to mass spectroscopy in which the resolution among the various ion masses is accomplished in space rather than time. A separate detector is associated with each...
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7429727 |
Method, apparatus, and program product for quickly selecting complex molecules from a data base of molecules
The disclosed technology relates to the analysis of dissociation spectrum data that includes spectral peaks that represent fragments of a parent ion. The parent ion includes molecular subunits that...
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7429730 |
SIFT-MS instruments
A SIFT or SIFDT apparatus in which the upstream quadrupole and the downstream quadrupole are housed within a single evacuated chamber with the upstream quadrupole being connected to the downstream...
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7427751 |
High sensitivity slitless ion source mass spectrometer for trace gas leak detection
A mass spectrometer includes a main magnet having spaced-apart polepieces which define a gap, the main magnet producing a magnetic field in the gap, an ion source to generate ions and to accelerate...
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7427750 |
Mass spectrometer assemblies, mass spectrometry vacuum chamber lid assemblies, and mass spectrometer operational methods
One embodiment of a mass spectrometer assembly includes a base configured to define at least a portion of a vacuum chamber volume; a mass separator component within the vacuum chamber volume; a lid...
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7425700 |
Systems and methods for discovery and analysis of markers
The present invention relates to systems and methods for identifying new markers, diagnosing patients with a biological state of interest, and marketing/commercializing such diagnostics. The...
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7423260 |
Apparatus for combined laser focusing and spot imaging for MALDI
A MALDI ion source includes a sample plate for receiving a sample, a laser for producing laser radiation to ionize the sample, a first optical element arranged so as to direct the laser radiation...
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7423259 |
Mass spectrometer and method for enhancing dynamic range
A mass spectrometer comprises an ion detector, a first amplifier, a second amplifier, and a spectra combiner. The ion detector is configured to generate an analog signal indicative of ions detected...
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7423261 |
Curved conduit ion sampling device and method
An ion sampling apparatus for use in a mass spectrometry system. The ion sampling apparatus includes a target support for receiving a sample, an irradiation source for emitting energetic radiation...
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7420180 |
Mass spectrometer and mass spectrometry
A mass spectrometer capable of measuring under switching two ion sources at different pressure levels in which a sample gas separated by GC column is branched, and separately introduced to a first...
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7420161 |
Branched radio frequency multipole
Systems and methods of the invention include a branched radio frequency multipole configured to act, for example, as an ion guide. The branched radio frequency multipole comprises multiple ion...
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