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6720554 |
Triple quadrupole mass spectrometer with capability to perform multiple mass analysis steps
A method of analyzing a substance comprises ionizing the substance to form a string of ions. The ions are then subject to a first mass analysis step. In one embodiment, the ions are accelerated...
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6717132 |
Gridless time-of-flight mass spectrometer for orthogonal ion injection
The invention relates to a time-of-flight mass spectrometer for injection of the ions orthogonally to the time-resolving axis-of-flight component, with a pulser for acceleration of the ions of the...
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6717138 |
Mask plate with lobed aperture
An apparatus and method for removing neutral noise from a quadrupole mass filter ion beam. A mask plate has a lobed aperture centered on a longitudinal axis and positioned between a quadrupole mass...
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6717131 |
Clean daughter-ion spectra using time-of-flight mass spectrometers
The invention relates to methods and instruments for measuring daughter-ion spectra in reflector time-of-flight mass spectrometers with post-acceleration of parent and daughter ions selected by...
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6717136 |
Microfludic system (EDI)
A microfluidic device comprising an MS-analyte presentation unit for a EDI-MS apparatus, said unit comprising an essentially planar support plate which on one side has one, two or more ports...
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6717130 |
Methods and apparatus for mass spectrometry
A method is disclosed of identifying parent ions by matching daughter ions found to be produced at substantially the same time that the parent ions elute from a mixture. Ions emitted from an ion...
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6717133 |
Grating pattern and arrangement for mass spectrometers
A method and apparatus for generating electrical fields within the ion flight path of a mass spectrometer are provided. Gratings having a planar array of parallel conductive strands and...
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6713757 |
Controlling the temporal response of mass spectrometers for mass spectrometry
A method and apparatus for operating a mass spectrometer system, having a processing section, provides for the application of both an axial field and periodic application of a flush pulse to the...
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6713758 |
Spherical side-to-side FAIMS
A high field asymmetric waveform ion mobility spectrometer (FAIMS) having spherical electrode geometry is disclosed. The spherical FAIMS includes an inner generally spherical electrode supported in...
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6713256 |
Fluorescent energy transfer mediated chemical activation (fetma) for the elucidation of the three-dimensional structure of biomacromolecules
The present invention relates to a method for the selected chemical activation of photo-activatable cross-linker molecules around ligand binding pockets and fluorescent groups in macromolecules,...
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6707032 |
Plasma mass spectrometer
A plasma mass spectrometer comprises a plasma torch ( 1 ) for generating ions from a sample introduced into a plasma ( 2 ), a nozzle-skimmer interface ( 3,5 ) for transmitting said ions into a...
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6707033 |
Mass spectrometer
In the time-of-flight mass spectrometer, after ions are accumulated in a quadrupole ion trap in a low vacuum chamber, the ions are ejected and transferred to a high vacuum chamber and are...
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6707034 |
Mass spectrometer and ion detector used therein
An ion detector includes an ion input face, a Faraday cup, an ion-to-electron converter dynode, two ion deflection electrodes, an electron multiplier portion, and an anode. The ion input face is...
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6707031 |
Laser optical bench for laser desorption ion sources and method of use thereof
A laser optical bench for use with a laser desorption/ionization mass spectrometer. The laser optical bench includes a laser for producing light, a focusing structure that receives light from the...
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6703611 |
Electrospray ionization device
An electrospray ionization device is provided that includes one or more electrospray needles and an ion sampling device. Each needle has a distal end for receiving a sample, a tip for spraying the...
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6703607 |
Axial ejection resolution in multipole mass spectrometers
An improved method of operating a mass spectrometer having a linear ion trap wherein ions are axially ejected from the trap to a detector or subsequent mass analysis stage. The DC barrier field...
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6700120 |
Method for improving signal-to-noise ratios for atmospheric pressure ionization mass spectrometry
A method of improving the signal to noise ratio of an ion beam, utilizing a tandem mass spectrometer comprising two mass filters separated by a collision cell. The first mass filter is operated in...
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6700117 |
Conditioning of an ion beam for injection into a time-of-flight mass spectrometer
The invention relates to a method and a device which reduces the phase space volume of ions in an ion beam in such a way that their injection into a downstream time-of-flight mass spectrometer...
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6683302 |
Method and device for electrospray ionization
The present invention relates to electrospray device and a method for heating a liquid in said electrospray device. The device comprising a liquid source ( 3 ), a mass analyser ( 5 ), and inlet...
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6680477 |
High spatial resolution matrix assisted laser desorption/ionization (MALDI)
Disclosed is an invention that provides a system and process for focusing light to micron and submicron spot sizes for matrix assisted laser desorption/ionization (MALDI). Moreover, the present...
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6680476 |
Summed time-of-flight mass spectrometry utilizing thresholding to reduce noise
A summed TOFMS having a filter for identifying detector outputs that are likely the result of noise rather than ions striking the ion detector. The TOFMS stores a plurality of data values at...
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6677593 |
Planar flow-by electrode capacitive electrospray ion source
An electrospray ion source includes a chamber including a channel region therein, the channel including at least one inlet for directing a solution into the channel and at least a first and a...
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6677583 |
Liquid chromatograph/mass spectrometer
The present invention proposes a liquid chromatograph/mass spectrometer (LC/MS) constructed so that only necessary data are efficiently collected, and that the apparent dynamic range and/or the...
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6677582 |
Ion source and mass spectrometer
An apparatus for detecting the minor constituents of a sample with high efficiency in positive and negative ion monitoring modes. The directions in which the sample gas is forced to flow in the...
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6670624 |
Ion implanter in-situ mass spectrometer
An apparatus for the in-situ detection of ions in a beam of an ion implanter device includes a mass spectrometer device having inner and outer walls and, a system for generating and directing an...
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6670607 |
Conductive polymer coated nano-electrospray emitter
The present invention relates to a nanospray emitter including an emitter body which includes a fluid inlet, an outlet orifice, and a passage communicating between the fluid inlet and outlet...
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6670606 |
Preparation of ion pulse for time-of-flight and for tandem time-of-flight mass analysis
The use of a segmented-ion trap with collisional damping is disclosed to improve performance (resolution and mass accuracy of single stage and tandem time-of-flight mass spectrometers. In the case...
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6667487 |
Radio frequency trap for containment of plasmas in antimatter propulsion systems using rotating wall electric fields
A containment apparatus for containing a cloud of charged particles comprises a cylindrical vacuum chamber having a longitudinal axis. Within the vacuum chamber is a containment region. A magnetic...
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6661003 |
Dielectric capillary high pass ion filter
For delivery of ions from a higher pressure ion source to a mass analyzer operating at high vacuum, high pass ion filtration is effected within a dielectric capillary interface between the higher...
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6661001 |
Extended bradbury-nielson gate
A method and apparatus for analyzing ions by determining times of flight include using a deflector to direct ions away from their otherwise intended or parallel course. Deflectors are used as...
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6657191 |
Means and method for multiplexing sprays in an electrospray ionization source
A means and method are disclosed for multiplexing a plurality of samples from multiple sprayer devices to be efficiently transferred to a mass analyzer for subsequent analysis. Sample sprays are...
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6653625 |
Microfluidic system (MS)
The present invention relates to a method for presenting an analyte of a liquid sample as an MS-analyte to a mass spectrometer. More particularly, the method comprises the steps of applying a...
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6653637 |
X-ray detector and charged-particle apparatus
In a high-sensitivity X-ray detector, an image of the secondary electrons is little shifted and deformed by the astigmatism or the like even when it approaches very close to a specimen set on the...
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6653624 |
Mass spectrograph
A mass spectrograph with an ionization chamber for having a sample liquid sprayed into and generating ions to be analyzed in a mass analyzing chamber for analyzing the generated ions has a...
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6653627 |
FAIMS apparatus and method with laser-based ionization source
Generally, the present invention provides a device for heating the sample stream inlet of an ion mobility spectrometry (IMS) sensor. The heating device increases the temperature of the sample...
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6653622 |
Ion fragmentation by electron capture in high-frequency ion traps
The invention relates to procedures and devices for fragmenting large molecules, preferably biomolecules, in high-frequency quadrupole ion trap mass spectrometers. The invention consists of...
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6646255 |
Liquid chromatograph/mass spectrometer and its ionization interface
The present invention proposes a liquid chromatograph/mass spectrometer constructed to present a maximized or almost maximized ion-producing efficiency of APCI, irrespective of whether positive or...
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6646254 |
Liquid chromatograph mass spectrometer
A liquid chromatograph mass spectrometer includes a solvent removing tube, a first ion lens and a second ion lens. Voltages applied to the solvent removing tube, and the first and second ion lenses...
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6642516 |
Apparatus and method of laser dissociation for mass spectrometry
Mass spectometer system and method of use are disclosed. Briefly described, one embodiment of the mass spectrometry system, among others, includes a radio frequency multipole assembly, an inner...
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6642515 |
Method and apparatus for electrospray mass spectrometric analysis
The invention is provides a method and an apparatus for performing electrospray ionization mass spectrometric analysis, which method can exactly analyze a mass of a molecular ion or a fragment ion...
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6639233 |
Apparatus for implanting an ion on a target and method for the same
An ion implantation apparatus includes an ion source for extracting ions therefrom at an extraction voltage, an acceleration pipe for accelerating the ions thus extracted at an acceleration voltage...
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6639222 |
Device and method for extracting a constituent from a chemical mixture
A device for separating a chemical mixture into its constituents includes a central cathode that is aligned axially within a cylindrical plasma chamber. An anode, made of the chemical mixture...
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6639213 |
Periodic field focusing ion mobility spectrometer
This invention is generally in the field of improved ion mobility spectrometry. The improvement lies in the use of periodic focusing electric fields that minimize the spatial spread of the...
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6639212 |
Method for separation of isomers and different conformations of ions in gaseous phase
The present invention relates to a method of separating ions having the same mass to charge ratio but different ion mobility characteristics, based on the ion focussing principles of high field...
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6635885 |
Apparatus for delivering calibration compounds to mass spectrometers and method
An apparatus for delivering calibrant gas at selected flow rates to the ionization region of a mass spectrometer which employs capillary flow restrictors for metering the flow.
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6633033 |
Apparatus for mass spectrometry on an ion-trap method
Depending on the RF driving voltage amplitude value and the frequency of each frequency component of wideband auxiliary AC voltages, the wideband auxiliary AC voltage comprising plural different...
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6633114 |
Mass spectrometer with electron source for reducing space charge effects in sample beam
A mass spectrometer includes an ion source which generates a beam including positive ions, a sampling interface which extracts a portion of the beam from the ion source to form a sample beam that...
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6633034 |
Method and apparatus for imaging a specimen using low profile electron detector for charged particle beam imaging apparatus including electrostatic mirrors
A charged particle beam method and apparatus use a primary electron beam to irradiate a specimen so as to induce the specimen to emit secondary and backscattered electrons carrying information...
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6630662 |
Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
To control movement of ions in a mass spectrometer, an ion guide has means for generating an electric field along the ion guide, and also provision for generating a gas flow along the ion guide....
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6627874 |
Pressure measurement using ion beam current in a mass spectrometer
Method and apparatus for rapid monitoring of pressure in a chamber equipped with a mass spectrometer by using the primary beam current in conjunction with a conventional pressure gauge. The...
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