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7632409 |
Cation-exchange displacement chromatography process and cationic organic compounds for use as displacer compounds in cation-exchange displacement chromatography process
A displacement chromatography process and displacer compounds used in the process and having the general formula (I):
wherein:
each group R 1 , R 2 , R 3 , R′ 1 , R′ 2 , and R′ 3 ,...
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7618539 |
Simulated moving bed chromatography for strongly retained compounds
Simulated moving bed (SMB) chromatography involving a series of columns serially connected in a circuit is performed in a modified protocol by dividing the columns into two groups isolated from...
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7615159 |
Method for the production of chemical and pharmaceutical products with integrated multicolumn chromatography
The invention relates to a chromatographic process for substance separation in the context of the preparation of chemicals such as, for example, chiral pharmaceuticals, isomers or biomolecules on...
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7594999 |
Multi column chromatography system
The present invention relates to a method and apparatus for chromatographically analyzing each of a plurality of samples in detector, comprising an autosampler to contain a plurality of samples for...
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7582206 |
Process and device for simulated moving bed separation with a reduced number of valves
A simulated moving bed (SMB) separation device comprising a column, beds Ai of adsorbent separated by plates Pi with a single distribution and extraction network for fluids, in particular feed F,...
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7582208 |
Process and device for simulated moving bed separation with a reduced number of valves and lines
The invention concerns a simulated moving bed adsorption separation device comprising a limited number of valves. According to the invention, the device comprises a column with a plurality of...
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7582207 |
Process and device for simulated moving bed separation with a reduced number of large diameter valves
The invention concerns a simulated moving bed (SMB) separation device and process comprising a column, beds A i of adsorbent separated by plates P i with a single distribution and extraction...
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7569141 |
Process and device for simulated moving bed separation with a reduced number of large diameter valves and a reduced line volume
The invention concerns a simulated moving bed adsorption separation device comprising a limited number of large diameter valves. According to the invention, the device comprises a column with a...
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7566395 |
Purification system
The present invention relates to automated chromatography systems and software for controlling such automated systems for optimising the purification of a protein from a sample. The software is...
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7566396 |
Flow path switching valve and high performance liquid chromatograph using the same
The present invention is directed to reduce the dead volume in a flow path with trap functions. A flow path switching valve 1 is provided, which includes a rotor, i.e., rotor 3 , and a housing...
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7556731 |
Liquid chromatograph
A liquid chromatograph having a flow passage switching mechanism for switching among a normal analysis flow passage formed by connecting a mobile-phase-sending-unit, a second mixer having a large...
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7550081 |
Mobile phase supplying apparatus, liquid chromatograph using the same, and mobile phase supplying method
In liquid-feeding sections for feeding two types of mobile phases A, B, respectively, actual flow rate measuring sections capable of detecting back-flows are provided in downstream of...
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7544293 |
Valve and process for interrupted continuous flow chromatography
A unique valve assembly for simulated bed moving chromatography employs a combination of pressure compatible sealable materials that permit minimal frictional interaction between moving parts,...
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7537694 |
Method and device for multidimensional liquid chromatography
In a liquid chromatography, an electrolytic solution starts to be supplied from an injector toward a specimen in a first separating column to transfer components of the specimen from the first...
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7488420 |
Chromatographic separator
A chromatographic separator characterized in that two pumps are employed for controlling chromatographic separation that combines a first process for supplying at least one of feed solution and...
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7488422 |
Method and apparatus for separating a target molecule from a liquid mixture
A simulated moving bed apparatus and methods are described for continuously separating a target molecule from a liquid mixture, using a simulated moving bed system. The simulated moving bed system...
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7479228 |
Method and device for chromatographic component separation
The invention relates to a process for the chromatographic separation of components ( 19, 20, 25, 26, 28, 29 ) of a multiple-component fluid mixture ( 2 a ) by means of the Simulated Moving Bed...
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7473368 |
Simulated moving bed separation process and device
A simulated moving bed (SMB) separation device comprises at least one column, beds of adsorbent arranged in this column, trays Pi with a chamber Ci for distribution and extraction of fluids, a...
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7413660 |
Single pass method and apparatus for separating a target molecule from a liquid mixture
A single pass simulated moving bed apparatus and methods are described for continuously separating a target molecule from a liquid mixture, using a simulated moving bed system. The simulated moving...
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7410586 |
Purification or work-up on ionic liquids by means of adsorptive separation processes
Process for the work-up of a mixture comprising ionic liquids and a further substance, wherein the substance present is separated off by means of adsorptive separation processes.
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7407586 |
Chromatographic separation
The invention relates to an equipment for fractionating a solution by a sequential SMB process, which equipment comprises a feed column and one or several other columns, which include a...
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7402250 |
Equipment and method for feeding liquid gradient in nano/micro liquid chromatography
It is an object of the present invention to improve the performance of gradient liquid transfer in nano/micro liquid chromatographs when solvents are mixed. In a gradient liquid transfer device...
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7399415 |
Parking a sample stream and suppressing the sample
Pretreatment method and apparatus to remove matrix ions from a liquid sample, prior to separation of the sample analytes (e.g. by chromatography), by flowing the liquid sample into a sample...
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7399898 |
Simulated moving bed adsorptive separation process for preventing increase in pressure drop and system thereof
Disclosed is a simulated moving bed (SMB) adsorptive separation system in which at least one component of a fluid mixture is brought into contact with a solid adsorbent and the adsorbed component...
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7396469 |
Backflow prevention for high pressure gradient systems
Gradient performance with high pressure gradient solvent delivery system is optimized by approximation of infinite stroke volume of high pressure pumps by the addition of pulse dampening with...
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7390412 |
Method of managing the valves of a simulated moving bed separation system
A method of managing the valves of a simulated moving bed separation system comprising at least one column of adsorbent beds split into several zones delimited by injection and draw-off points,...
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7361273 |
Separation of sugars, sugar alcohols, carbohydrates and mixtures thereof
The present invention relates to a method of separating sugars and sugar alcohols from each other. More particularly the present invention relates to the use of a weakly basic anion exchange resin...
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7361269 |
Fraction collector with adjustable tray
A fraction collector comprising a movable tray is provided. The movable tray may be attached to the fraction collector support system in a variety of ways and adjusted without adjusting the parts...
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7332087 |
Flow sensing apparatus used to monitor/provide feedback to a split flow pumping system
A method and apparatus for monitoring and controlling the nano-scale flow rate of fluid in the operating flow path of a HPLC system without relying on a nano-scale sensor in the operating flow...
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7314551 |
Flow distribution apparatus
Disclosed is a mixer-distributor-collector apparatus for use between beds of solid particles in a fluid-solid contacting vessel. The apparatus includes a solids retaining screen, fluid deflector,...
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7314567 |
Method for transferring heterogeneous liquids in microchannels without the occurrence of mixing
In the method for mixing-free transport of homogeneous liquids in microchannels a heterogeneous liquid flow ( 14 ) is autonomously divided into portions, transported over a distance and then...
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7306734 |
Method for separation of enantiomeric isomers by simulated moving bed chromatography
The present invention provides a method having a high productivity for preparative separation by simulated moving bed chromatography. That is, in a filler for enantiomeric isomer separation by...
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7288200 |
System for injecting a by-pass fluid in a separation method in a simulated moving bed
Device and process for separating at least one compound from a mixture in a simulated moving bed, comprising:
an enclosure comprising several absorbent beds, two adsorbent beds being...
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7285219 |
Chromatographic separation member and method
There is described a chromatographic separation member including a substrate carrying on at least one surface a thin layer of a chromatographically active capture material. Also described is a...
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7229558 |
Chromatographic separation method
A method for fractionating a solution into two or more fractions. More particularly the invention relates to a method for fractionating a solution by a chromatographic simulated moving bed (SMB)...
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7229551 |
Diffusion promoting device for low flow velocity gradient high performance liquid chromatography
Device for improving detection sensitivity in low flow velocity high performance liquid chromatographic apparatus. Preferredly, diffusion promoting device connected at just before separation column...
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7220356 |
Method of purifying polypeptides by simulated moving bed chromatography
Provided are methods of separating an immunoreactive compound from at least one immaterial component, using a simulated moving bed (“SMB”) system and a SMB apparatus for use in these methods....
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7192526 |
Method of optimizing the operation of a xylene separation unit using simulated countercurrent
Method of optimizing the operation of a unit intended for separation of the components of a feed (xylenes) by simulated countercurrent in hybrid operating mode. The method allows to minimize the...
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7189324 |
High-affinity, low molecular-mass displacers for ion-exchange chromotography
A method for separating one or more components of a biomolecule mixture by means of an ion exchange chromatographic system operated in the displacement mode includes sequentially perfusing the...
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7186336 |
Flow sensing apparatus
A method and apparatus for monitoring and controlling the nano-scale flow rate of fluid in the operating flow path of a HPLC system. A first flow sensor is disposed in a first flow path between a...
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7169308 |
Liquid chromatograph control apparatus, method for performing liquid chromatography and computer program for controlling a liquid chromatograph
A liquid chromatograph control apparatus ( 1 ) includes a measured value storage ( 25 a ) that stores a measured retardation factor (Rf) value of a sample ( 3 ), which is obtained when components...
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7144502 |
Chromatography system with gradient storage and method for operating the same
In accordance with one aspect of the present invention, an ultra-high pressure chromatography system (UHPLC) is provided and includes a high pressure chromatography arrangement of equipment (HPLC...
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7141172 |
Versatile simulated moving bed systems
Distributed valve simulated moving beds are described in which junctions located between successive columns interrupt the flow of process fluid between columns, and either transmit the process...
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7138050 |
Fractionating/collecting device of liquid chromatograph
In a preferred embodiment, a sample container storage part for storing a number of sample containers S, a nozzle for dropping a sample component separated and supplied by an LC and an additive...
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7138518 |
Liquid chromatographic separation of polynucleotides
In one aspect, the invention provides a method for separating a mixture of polynucleotides, such as DNA or RNA, including (a) applying the mixture to a polymeric separation medium having non-polar...
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7128833 |
Chromatographic separation
The invention relates to an equipment for fractionating a solution by a sequential SMB process, which equipment comprises a feed column and one or several other columns, which include a...
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7097770 |
Separation of plant oil triglyceride mixtures by solid bed adsorption
A solid bed adsorptive process for separating a seed oil into two substantially pure triglyceride fractions. The process involves contacting a seed oil, such as castor oil, preferably as a...
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7074334 |
Method for determining the binding behavior of ligands which specifically bind to target molecules
The invention relates to a method for determining the binding behavior of ligands which specifically bind to target molecules at at least one binding site, whereby the markers are present in a...
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7060188 |
Separation system and process
The invention relates to a system and a process for fractionating a solution into two or more fractions. The system of the invention comprises at least two compartments having a diameter of at...
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7022239 |
Method for fractionating liquid mixtures
The present invention relates to a method of fractionating liquid mixtures or solutions, comprising the steps of subjecting a feed in the form of a liquid mixture or solution to a first...
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