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6818134 |
Systems and methods for screening and optimization of solid oxide fuel cell materials
Systems and methods for high-throughput fabrication and evaluation of electrode and electrolyte material performance for solid oxide fuel cells. A system comprising a substrate, an auto-sampler...
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6814870 |
Microchip electrospray device and column with affinity adsorbents and use of the same
A microchip-based electrospray ionization device and column with affinity adsorbents is disclosed. The invention includes a microchip array and a capillary tube or alone or attached in combination....
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6814859 |
Frit material and bonding method for microfluidic separation devices
A frit for use in multi-layer microfluidic separation devices is provided. The frit comprises a polymeric membrane that may be securely bonded within the device and minimizes lateral wicking. A...
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6811688 |
Chromatography columns
A chromatography column suitable for small-scale laboratory use as a column tube resembling that of a syringe and a movable plunger which slides in the column tube. End filter arrangements are...
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6811969 |
Retentate chromatography—profiling with biospecific interaction adsorbents
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...
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6812458 |
Systems and methods for high-throughput microfluidic sample analysis
Systems and methods for collecting the output of multiple simultaneously operated chromatography columns and providing the outputs to a single mass spectrometer are provided. Such systems utilize...
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6812030 |
System and method for high throughput sample preparation and analysis using column chromatography
A system and method high throughput sample preparation and analysis using column chromatography. Each port in a plurality of ports has a port input that interfaces with a first fluid source and a...
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6808933 |
Methods of enhancing confidence in assays for analytes
Methods are disclosed for enhancing the confidence index in detecting the presence and/or amount of an analyte suspected of being in a sample. In the method, a combination of at least two...
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6805793 |
Separatory material with the use of stimulus-responsive polymer and separation method by using the separatory material
A novel method for separating a target substance, for example, metal ion, drug or biological component is provided. According to the method, the surface of a packing undergoes a chemical or...
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6802968 |
Chromatography apparatus
An apparatus for use in liquid chromatography involves a column filled with media bounded axially by first and second porous plates. The column has an inlet end with an inflow region between the...
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6802969 |
Preparative chromatography system and separation/purification method using same
A prepartive chromatography system, and a separation and purification method using the system, are provided for small scale, low cost, efficient multicomponent separation and purification without...
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6802967 |
Multi-dimension liquid chromatography separation system
Liquid chromatography based on the difference of two or more kinds of separation modes, (e.g., chemical or physical properties of analytes) may improve separations when samples contain complex...
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6803200 |
Compositions and methods for the release of nucleic acid molecules from solid matrices
The present invention relates to compositions and methods for releasing nucleic acid molecules from solid matrices. The invention further relates to compositions and methods for purifying and...
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6800438 |
Imager for DNA sequencer
An improved method for the sequencing of DNA fragments is provided. The method includes using a known process for DNA fragment separation, such as capillary electrophoresis, and imaging the...
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6800202 |
Integrated monolithic microfabricated electrospray and liquid chromatography system and method
An electrospray device, a liquid chromatography device and an electrosprayliquid chromatography system are disclosed. The electrospray device comprises a substrate defining a channel between an...
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6797174 |
Connecting system for plastic columns
The invention relates to a plastic cartridge system including a cartridge having a plastic-covered column, said column including a monolithic sorbent and at least one closing cap which is applied...
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6797523 |
Methods for systematic identification of protein—protein interactions
The present invention relates to a method for identifying protein—protein interactions. The interacting proteins are isolated by affinity chromatography and identified by mass spectrometry. The...
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6793815 |
Pumping arrangement
A pumping arrangement, for example for liquid chromatography, includes a first liquid reservoir at a first height level, connected via a first hydraulic path to a pumping device; a second liquid...
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6790361 |
Mobile phase dilution scheme for enhanced chromatography
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a...
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6787030 |
Effluent collection apparatus and method
The present invention includes a method of analyzing one or more molecular components in a mixture of components. In the method, a mixture of molecular components, i.e., an analyte mixture, is...
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6783929 |
Biological sample component purification and differential display
Provided are affinity support materials having intermediate binding affinity for biological samples. Among the materials provided by the present invention are hydrophilic solid supports composed of...
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6783680 |
Sample preconcentration tubes with sol-gel surface coatings and/or sol-gel monolithic beds
A method of preconcentrating trace analytes is accomplished by extracting polar and non-polar analytes through a sol-gel coating. The sol-gel coating is either disposed on the inner surface of a...
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6783988 |
Methods for quantitative and qualitative analyses of phospholipids using one-dimensional thin layer chromatography
A highly sensitive and specific method for the detection and quantification of lipids is provided. Specifically, methods for the simultaneous detection and quantification of phospholipids extracted...
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6783673 |
Composite chromatography column
Apparatus for chromatography, featuring a composite chromatography column including a tubular member having an inlet end and an outlet end, where the tubular member includes an innermost first...
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6783672 |
Integrated high throughput system for the mass spectrometry of biomolecules
Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to...
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6780325 |
Diffusion promoting apparatus for low flow velocity gradient high-speed liquid chromatography
The present invention provides a device for improving detection sensitivity and a method for improving the detection sensitivity for use in a low flow velocity high performance liquid...
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6780315 |
Backflow prevention for high pressure gradient systems
Gradient performance with high pressure gradient solvent delivery system is optimized by approximation of infinite stroke volume of high pressure pumps by the addition of pulse dampening with...
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6776902 |
Parallel high-performance liquid chromatography with post-separation treatment
High-performance liquid chromatography (HPLC) methods and systems are disclosed that combine parallel chromatographic separation of a plurality of samples with a detection technique that involves...
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6776911 |
Methods for surface modification of silica for use in capillary zone electrophoresis and chromatography
The present invention refers to the use of novel molecules able to bind tenaciously to silica, borosilicate and silicate surfaces, and thus to modify their properties and characteristics. When...
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6777526 |
OPTICALLY ACTIVE MALEIMIDE DERIVATIVES, OPTICALLY ACTIVE POLYMALEIMIDE DERIVATIVES, PRODUCTION METHOD THEREOF, SEPARATING AGENT USING THE SAME DERIVATIVE, AND METHOD FOR SEPARATING OPTICALLY ACTIVE COMPOUNDS USING THE SAME AGENT
A separating agent that serves as an optical resolution agent is composed of a novel, useful optically active polymer. The separating agent is obtained through anionic polymerization of a novel...
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6773583 |
Water-wettable chromatographic media for solid phase extraction
A method for removing an organic solute from a solution comprises contacting the solution with a polymer formed by copolymerizing one or more hydrophobic monomers and one or more hydrophilic...
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6770757 |
Method for recovering products from process solutions
The invention relates to a method comprising a multistep process for recovering betaine, erythritol, inositol, sucrose, mannitol, glycerol and amino acids from corresponding starting materials. The...
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6770195 |
Compact automated radionuclide separator
A method and apparatus are provided for automatically separating radionuclides using a chromatographic separation process. The method includes the steps of displaying a first flow diagram on a...
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6762057 |
Separation apparatus including porous silicon column
A sample separation apparatus including a porous, or rough, capillary column. The porous capillary column includes a matrix which defines pores, and may be formed from a material such as porous...
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6758967 |
Liquid chromatography apparatus having two stationary phases
An ion exchange chromatography apparatus includes a first stationary phase and a second stationary phase. The first stationary phase has at least one complexing agent functional group capable of...
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6758966 |
Capillary columns employing monodispersed particles
A capillary column comprising monodispersed particles. The capillary is formed using a suitable substrate, wherein two plates are bonded together. At least one of the plates comprises a channel...
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6752927 |
Suppressed chromatography and salt conversion system
Method and apparatus for suppressed ion analysis in which a sample solution of analyte (e.g., anion) in an eluent of electrolyte counterions (e.g., sodium), is chromatographically separated. Then,...
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6749749 |
Separation system, components of a separation system and methods of making and using them
Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston...
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6749756 |
Reaction and separation methods
A method of separating compounds that includes the steps of: tagging at least a first organic compound with a first tagging moiety to result in a first tagged compound; tagging at least a second...
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6746608 |
Use of adsorbent polymer particles in DNA separation
The invention is directed to fluorinated particles having adsorbent properties for superior performance as the stationary phase for use in chromatographic separations. In particular, the...
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6746607 |
Use of an adsorbent gel for eliminating and purifying biomolecules
The invention concerns the use of an adsorptive size exclusion chromatography gel, said gel essentially consisting of a polysaccharide matrix whereon is grafted a polymer coupled with an affinity...
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6746695 |
Pharmaceutical preparations of bioactive substances extracted from natural sources
This invention relates to methods of extracting and purifying bioactive substances from various plants and herbs. More specifically the invention relates to methods of extracting and separating...
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6743364 |
Method and system for identifying and quantifying chemical components of a mixture
Method and system for processing and evaluating data from combination chromatographic and mass spectrometric data. The methods and system comprise data smoothing and determination of an quality...
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6743356 |
High throughput high performance chromatography system
A high throughput high performance chromatography system operating at a high mixing pressure including a plurality of pressurized solvent reservoirs, e.g. pumps, each maintaining an associated...
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6740242 |
Plating apparatus and method of managing plating liquid composition
A plating apparatus comprises a plating unit having a plating bath for holding a plating liquid therein, and a planting monitoring unit having a liquid chromatography device and an arithmetical...
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6740241 |
Chromatography column system and method of packing of a chromatography column
A method of packing a chromatography column ( 101 ) with a chromatography media ( 104 ) from a vessel ( 102 ) in which the chromatography media ( 104 ) is pumped into the chromatography column (...
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6740243 |
Systems and processes for performing separations using a simulated moving bed apparatus
Systems and processes are provided that are useful for separating components from feed streams containing multiple components. Systems and processes of the present invention are based on simulated...
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6736967 |
Separating agent for enantiomeric isomers
A separating agent for enantiomeric isomers has an enantiomerically active polymer compound supported thereon. The polymer compound has an exothermic peak before a decomposition temperature of the...
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6736975 |
Method of separating compound(s) from mixture(s)
The invention relates to methods of separating compounds of interest from mixtures using high performance liquid chromatography (HPLC). An initial separation of a sample of a mixture is performed...
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6736958 |
Ion sensing method
The present invention allows the determination of trace levels of ionic substances in a sample solution (ions, metal ions, and other electrically charged molecules) by coupling a separation method,...
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