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6491816 |
Apparatus for parallel high-performance liquid chromatography with serial injection
High-performance liquid chromatography (HPLC) methods and systems are disclosed that combine sequential, serial injection of a plurality of samples into mobile-phases supplied in parallel to two or...
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6488857 |
Method of separating hemoglobin A2
A method for separating hemoglobin A 2 from a hemoglobin mixture according to a cation exchange liquid chromatography characterized that at least two types of eluents are used including an eluent...
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6485642 |
Liquid chromatograph
A sample solution is sent into a concentration column through a three-way joint and a three-way switching valve to trap and concentrate the sample components on the concentration column, followed...
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6486309 |
Method of detecting sequence variations in macromolecules by thermal gradiant
The present invention describes a method for separating macromolecules, particularly heteroduplex from homoduplex DNA molecules. The macromolecules undergo a temperature sensitive structural...
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6485648 |
MIPC column cleaning system and process
An apparatus for effecting base pair length separations of DNA fragments by matched ion paired chromatography comprising a separation column containing separation media having non-polar DNA...
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6482867 |
Polymer packing material for liquid chromatography and a producing method thereof
There are disclosed a polymer packing material suitable for liquid chromatography and a producing method thereof. The polymer packing material having a polymer particle based on a styrene skeleton...
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6475389 |
Method for detection of prostate specific membrane antigen in serum
A method for detecting prostate specific membrane antigen (PSMA) in serum by immunoassay including the steps of capturing PSMA from serum using a PSMA antibody and detecting the captured PSMA with...
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6475390 |
Process for the purification of nutrients from food process streams
A separation process is described for separation of a nutrient from divalent ions of an aqueous solution. The aqueous solution is contacted with an ion exchange resin that includes monovalent ions...
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6475391 |
Rapid characterization of polymers for combinatorial, analytical and process control applications
A method is disclosed for characterizing a plurality of non-biological polymer samples. The method includes the steps of injecting four or more non-biological polymer samples into a mobile-phase of...
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6471866 |
Process for performing polynucleotide separations
The invention recognizes the deleterious effects of trace, and even undetectable amounts of multivalent cations on the separation of mixtures of polynucleotides, especially double stranded...
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6468733 |
Method of the inactivation of viruses by a solvent-detergent combination and nanofiltration
The invention concerns a method for elimination of viruses from a biological preparation wherein initially enveloped viruses are eliminated by a solvent-detergent step, then the solvent-detergents...
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6468748 |
Methods of screening nucleic acids using volatile salts in mass spectrometry
This invention relates to methods for screening nucleic acids for mutations by analyzing nonrandomly fragmented nucleic acids using mass spectrometric techniques and to procedures for improving...
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6468804 |
Suppressor for continuous electrochemically suppressed ion chromatography and method
Methods and devices for continuous electrochemically suppressed ion chromatography are disclosed. In preferred aspect of the invention, a chloromatography effluent comprising analyte ions and...
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6464882 |
Annular chromatograph
The invention related to an annular chromatograph including a particle bed which rotates on a rotary plate ( 3 ), said plate having eluate drainage lines, with regard to a stationary base and a...
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6461515 |
Parallel liquid chromatography for analyzing combinatorial libraries of non-biological polymers
A method is disclosed for characterizing non-biological polymers using liquid chromatography that is particularly useful in polymer research programs. The method includes the steps of providing a...
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6458273 |
Sample separation apparatus and method for multiple channel high throughput purification
A high throughput liquid chromotagraphy column assembly for separating a large sample with a selected mass weight and fluid volume. The assembly includes a loading column with a loading chamber...
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6454948 |
Distributor-mixer-extractor of fluids and associated process
Device (DME) or panel for collecting, distributing, mixing or drawing off several fluids, at least one main fluid and at least two secondary fluids, that comprises at least: means for collecting a...
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6454947 |
Overlaid injection for rapid characterizations of polymers
A method is disclosed for characterizing a plurality of non-biological polymer samples. The method includes the steps of injecting a first non-biological polymer sample into a mobile-phase of a...
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6455692 |
Method of concentrating polynucleotides using MIPC
The present invention is directed to improved methods for detection of mutations in DNA using Denaturing Matched Ion Polynucleotide Chromatography (DMIPC). The invention includes the following...
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6444475 |
Ion chromatography apparatus and method for removing gas prior to sample detection
Methods and devices for removing gas prior to detecting analyte ions are discolored. In one aspect of the invention, gas by-products from the suppression of the mobile phase are removed prior to...
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6444122 |
Liquid chromatography column
A chromatography cartridge assembly includes a cartridge and first and second end caps. A wall of the cartridge defines a chamber for containing chromatography media. The end caps define inlet and...
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6444150 |
Method of filling a microchannel separation column
A method for packing a stationary phase into a small diameter fluid passageway or flow channel. Capillary action is employed to distribute a stationary phase uniformly along both the length and...
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6440301 |
Chromatography resin support
An apparatus and method of using an improved chromatography resin support is disclosed. The chromatography support platform is provided by a stainless steel hollow cylinder adapted for being...
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6428702 |
Method of sample introduction for supercritical fluid chromatography systems
An improved method and apparatus for safely introducing sample into a flow stream of a supercritical fluid chromatography system is described. The sample injection method improves safety of...
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6428703 |
Method for purifying biological marcromolecules, and chromatographic column for performing said method
The invention concerns a method for purifying biological macromolecules, e.g. nucleic acids or proteins, from starting materials, in which the macromolecules, contained in a biological solution,...
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6428704 |
Method for determination of hemoglobins
A method for determining hemoglobins is provided which is suitable for determination of stable hemoglobin A 1c . A method for determining hemoglobins by cation exchange liquid chromatography...
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6425284 |
Method and apparatus for gas-assisted suppressed chromatography
Ionic species in an aqueous sample stream are analyzed by (a) chromatographically separating the ionic species in the presence of an aqueous eluent solution comprising electrolyte to form a...
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6426006 |
Automated on-line evaporating light scattering detection to quantify isolated fluid sample compounds in microtiter plate format
Single pass methods and systems for measuring the total masses of individual compounds present in fluid samples in real time, and particularly for fluid samples prepared in microtiter plate format...
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6423120 |
Sample introduction systems and methods
A preferred sample introduction apparatus includes a wall that defines a channel, with the channel being configured to receive a sample and being adapted to engage in fluid communication with the...
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6419828 |
Method for the separation of acid from sugars
A method for separating acid and sugars obtained from liquids resulting from the acid hydrolysis of a material containing at least one of cellulose and hemicellulose is disclosed, comprising adding...
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6418781 |
System for analyzing trace amounts of impurities in gases
An analyzing apparatus for assaying various kinds of trace impurity contents in various kinds of high-purity gases, having an atmospheric pressure ionization mass spectrometer useful for...
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6420028 |
Coated polymer article and its use
A polymer article having structure (I), where P comprises the basic polymer and groups —L—CH(—X(R 1 ) p )—CH 2 (—Y(R 2 ) p ); L is a part of a pending group utilized for introducing...
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6419824 |
Apparatus and method for separating and purifying polynucleotides
The disclosure describes an ambient or low pressure device for separating polynucleotide fragments from a mixture of polynucleotide fragments comprises a tube having an upper solution input...
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6416716 |
Sample preparation device with embedded separation media
The present invention relates to a novel device for small sample preparation using tubes and columns, such as capillaries or pipette tips, in which particles of a separation medium, such as...
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6416663 |
Chromatographic column for rapid characterizations of polymers
Rapid characterization and screening of polymer samples to determine average molecular weight, molecular weight distribution and other properties is disclosed. Rapid flow characterization systems...
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6413431 |
HPLC method for purifying organic compounds
An HPLC method which purifies and/or characterizes large numbers of related compounds, for example, those prepared for use in combinatorial libraries, is disclosed. The compounds are purified on a...
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6406632 |
Rapid characterization of polymers
Rapid characterization and screening of polymer samples to determine average molecular weight, molecular weight distribution and other properties is disclosed. Rapid flow characterization systems...
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6402953 |
Adsorption means for radionuclides
The invention relates to adsorption material for radionuclides based on a fine fibrous material containing chitin. The material is obtained from fungi and insoluble ferrocyanides of the transition...
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6402947 |
Interphase device for the direct coupling of liquid chromatography and gas chromatography
The basic structure of a PTV (programmed temperature vaporizer) injector has been considerably modified so that is can be used for the direct coupling of liquid chromatography in normal phase or...
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6402959 |
Fluid distributing-collecting system process
A fluid distributing-collecting process using a device for bringing fluids and solids into contact comprises several distributor plates and several panels for mixing, distributing or extracting...
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6402958 |
Chromatography column loading method
An adsorbent bed is loaded into an HPLC column by a method which comprises fluidization of the adsorbent. The adsorbent may be added as a slurry which is then fluidized and not allowed to settle....
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6398962 |
Use of monolithic sorbents for preparative chromatographic separation
The invention relates to use of monolithic sorbents for preparative separation processes, specially for processes according to the simulated moving bed (SMB) principle.
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6398953 |
Chromatography cartridge end cap fixation
A method of forming a chromatography cartridge includes providing a flexible-walled tube, placing a first end cap within the tube in sealing engagement with the tube wall, forming a media bed...
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6395183 |
Method for packing capillary columns with particulate materials
Method for loading a capillary channel with a packing material to form a capillary column which comprises placing a first frit on a first capillary channel, forcing a slurry of a solid packing...
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6395179 |
Thermally-managed separation and dewatering processes for recovering acid products
Described are preferred processes separating desired chemical products from impurities in solution utilizing thermally-managed chromatography over solid adsorbents. The preferred processes involve...
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6391196 |
Chromatography apparatus
Disclosed is an assembly for continuous annular chromatography provided with a relative movement between one partial bed in the form of a cylinder jacket, at least one feeding position for liquid...
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6387258 |
Method of purifying statins from a fermentation broth
A process for purifying statin compounds from a fermentation broth by extraction and crystallization is disclosed. A fermentation broth is subjected to a pretreatment procedure which involves an...
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6387268 |
Immobilization of membrane receptor on HPLC
This invention provides a immobilized receptors on supports in liquid chromatographic systems. The method of the invention provides means of evaluating the attachment of agents to receptors...
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6387256 |
Chromatography column
A chromatography column is disclosed. The large diameter chromatography column comprises a column body with threaded end portions. At each of the end portions, a respective filter housing is...
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6387974 |
Polymeric adsorbents and method of preparation
Macroporous polymers having selected porosity and permeability characteristics that provide rigid polymer matrices suitable for use in medium and high pressure reversed phase liquid chromatography...
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