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6730228 |
Methods and apparatus for characterization of polymers using multi-dimensional liquid chromatography with regular second-dimension sampling
Methods and apparatus for characterizing a polymer sample and in preferred embodiments, libraries of polymer samples, in a comprehensive, directly-coupled multi-dimensional liquid chromatography...
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6726843 |
Inverse chromatography methods and apparatus for evaluation of interactions between modifying agents and receptors comprising natural or artificial mammalian tissue
Methods and apparatus for the evaluation of interactions between substances using inverse chromatography are disclosed. Preferably, interactions are evaluated between a liquid test sample and a...
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6723985 |
Multiple electrospray device, systems and methods
A microchip-based electrospray device, system, and method of fabrication thereof are disclosed. The electrospray device includes a substrate defining a channel between an entrance orifice on an...
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6723157 |
Material for capturing chemical substance, method for producing the same, and chemical substance-capturing tube
A material is provided for capturing a chemical substance comprising fibers which carry metal alkoxide particles on the surfaces thereof. The metal alkoxide particles are made from an oligosilica,...
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6723235 |
Apparatus for screening compound libraries
Disclosed are apparatus for screening compound libraries using frontal chromatography in combination with mass spectrometry to identify and rank those members of the library that bind to a target...
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6719899 |
Access valve devices, their use in separation apparatus, and corresponding methods
An access valve suitable for controlling fluid flow into and out of a chromatography column has a central axially movable probe with a head acting as a spool valve in a barrel. Axial movement of...
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6720190 |
Methods for screening compound libraries
Disclosed are methods for screening compound libraries using frontal chromatography in combination with mass spectrometry to identify and rank those members of the library that bind to a target...
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6717136 |
Microfludic system (EDI)
A microfluidic device comprising an MS-analyte presentation unit for a EDI-MS apparatus, said unit comprising an essentially planar support plate which on one side has one, two or more ports...
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6712085 |
Method for the provision of fluid volume streams
The invention concerns a method supplying volume streams of fluids in channels or capillaries of small stream cross sections, more particularly chromatographic separating columns for the analytical...
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6712973 |
Process and device for separation with variable-length chromatographic zones
A process for separating at least one component of a mixture in a set of closed-loop chromatographic columns is described, whereby the loop comprises at least one feedstock injection point, a...
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6712963 |
Single-use manifold for automated, aseptic transfer of solutions in bioprocessing applications
Presteralized manifolds are provided which are designed for sterile packaging and single-use approaches. Disposable tubing and flexible-wall containers are assembled via aseptic connectors. These...
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6712962 |
Ion chromatography system for exchanging an ion exchanger in a suppressor and a suppressor means
An ion chromatography system having a suppressor means which is provided with a main body for accommodating an ion exchanger ready for measuring; a chamber for accommodating a virgin ion exchanger,...
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6709583 |
Continuously regenerated and integrated suppressor and detector for suppressed ion chromatography and method
An integrated suppressor and detector for suppressed ion chromatography includes a stationary phase, a fluid flow path, at least first and second regeneration electrodes, and at least first and...
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6709597 |
Process for the separation of racemic mixtures
The present invention relates to a process for the separation of racemic mixtures comprising development of a denser molecular imprint on silica with a desired enantiomer by sol-gel protocol.
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6709596 |
Device, method and system for reversibly trapping and isolating carbohydrates
Disclosed herein is a reversible carbohydrate (glycan) trap, methods and system for preparing the trap and use of the trap in preparing and trapping glycans for the study of carbohydrate structure....
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6706187 |
Packing material for chromatography having novel characteristic and method for isolation of substance using the same
To provide chromatographic packings whereby biological components, etc. which cannot be separated by either ion-exchange chromatography or reversed phase chromatography employed alone can be...
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6706191 |
Chromatographic process utilizing a fluidized bed
A liquid chromatographic process performed at least partly in a fluidised bed contained in a vessel and comprising particle fluidised by an upwardly directed liquid flow, said process comprising...
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6706192 |
Purification process
Object of the invention is a process for the chromatographic purification of cyclosporin A from a crude product containing cyclosporin complex by using a column filled with silica gel and by the...
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6706188 |
Process and means for down stream processing
A method for recovering a desired component from a sample solution with beads under stabilized fluidized bed conditions is provided. Also provided are support beads for use in downstream processing...
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6706177 |
Open capillary column and manufacturing method thereof
In an open capillary column, a stationary phase is formed on the inner wall of a capillary tube. This stationary phase comprises a number of pores on the surface of the capillary tube, and each of...
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6702943 |
Method for anion-exchange adsorption and anion-exchangers
A method for the removal of a substance carrying a negative charge and being present in an aqueous liquid (I). The method comprises the steps of: (i) contacting the liquid with a matrix carrying a...
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6699392 |
Method to fabricate silicon chromatographic column comprising fluid ports
A new method for fabricating a silicon chromatographic column comprising through-substrate fluid ports has been developed. This new method enables the fabrication of multi-layer interconnected...
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6699386 |
Endotoxin adsorbent, and a method of removing endotoxin by using the same
This invention provides an adsorbent having a high ability to adsorb endotoxin selectively and a method of adsorbing endotoxin. The adsorbent comprises a basic substance bonded to a base material...
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6695969 |
Process for obtaining HMG-CoA reductase inhibitors of high purity
Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as and antihypercholesterolemic agents....
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RE38435 |
Separating agent
A mixture of chemical substances such as optical isomers, geometrical isomers and polymers having different molecular weight ranges is separated to each ingredient by use of a cellulose derivative...
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6692643 |
Method for detecting PSA and its molecular forms using thiophilic gel on magnetic beads
A method for capturing PSA and its molecular forms that may be in a fluid biological material including the steps of: preparing a bed of magnetic beads by binding thiophilic ligands to the beds...
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6692577 |
Process for purifying maltose
The invention relates to a process for purifying a maltose-containing liquor from a undesired impurities, such as maltotriose. The process of the invention is characterized by nanofiltering said...
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6685841 |
Nanostructured devices for separation and analysis
The present invention provides a matrix comprising an array of nanostructures that exhibit a variation (gradient) in physical properties (such as size or pitch) in at least one direction of the...
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6685828 |
Automated sample collection in supercritical fluid chromatography
A system for collection of liquid phase sample fractions from a supercritical fluid chromatography system is disclosed. The system has different ways of gathering the liquid phase into a collection...
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6685837 |
Method for separating and analyzing hydrogen ion and ion chromatographic instrument
A method for the separation of hydrogen ion, characterized in that a substance having a conjugate base (A − ) of an acid (HA) as a functional group is used as a stationary phase, and an...
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6679989 |
Integral, thru-bore, direct coupled high pressure liquid chromatography guard column
Guard columns for high-pressure liquid chromatography (HPLC) apparatuses. These guard columns can be removable and/or metallic guard columns. Further, all of the outlet of the guard column can...
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6670024 |
Glass-silicon column
A glass-silicon column that can operate in temperature variations between room temperature and about 450° C. The glass-silicon column includes large area glass, such as a thin Corning 7740...
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6663779 |
Autoclavable annular chromatograph
A continuous annular chromatography (CAC) device is disclosed including a stationary column head, a stationary eluate ring, a rotating body which is located between said column head and said...
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6656354 |
Apparatus and method for preparative supercritical fluid chromatography
A fractionated sample collection process and device having at least one pressurized chamber used to gather and store liquid samples generated from a flow stream containing a mixture of highly...
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6652746 |
Chromatography system for automatically separating different compounds in a sample
A chromatography system including a chromatography column connected to receive a sample and separate different compounds in the sample, a flow-through detector that outputs a signal indicating the...
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6641736 |
Permanently radially compressed column
An embodiment of the present invention features a chromatographic device. The chromatographic device comprises a body having a cylindrical wall having an exterior diameter. The cylindrical wall is...
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6638710 |
Adsorbent for reducing the concentration of fibrinogen and/or fibrin, method of producing an adsorber from the adsorbent, and an adsorber with the adsorbent
An adsorbent for reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma comprises a matrix and synthetic lateral chains that are covalently bonded to the matrix. The...
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6635174 |
Foamed material filled with inner material
A matrix including: a) a polymeric base matrix including macropores (pore system 1) and b) an interior material, possibly porous (pore system 2), retained within the macropores. The matrix is...
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6632353 |
Rapid sample collection in supercritical fluid chromatography
A process and device for chromatography, such as preparative and analytical supercritical fluid chromatography, or supercritical fluid extraction for a liquid phase SFC collection system that...
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6630354 |
Chromatography using microwave pulsing
A method of using microwave-induced dielectric polarization to enhance the diffusivity of a liquid or a supercritical fluid mobile phase in chromatography, while having essentially no effect on...
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6627075 |
Device for and process of preparing volume flows of liquids in at least one passage of a chromatographic column
Volume flows of liquids in capillary tubes of chromatographic separation columns for analytical liquid measuring technology are controlled. The volume flows are derived from a liquid transport,...
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6627076 |
Compact microchannel system
The present invention provides compact geometries for the layout of microchannel columns through the use of turns and straight channel segments. These compact geometries permit the use of long...
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6623630 |
Method and apparatus for monitoring a fluid system
An apparatus for monitoring a fluid system particularly suited for use with high pressure liquid chromatography systems. The apparatus monitors seal leakage as well as the general wellness of the...
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6620326 |
Expanded bed adsorption system
The present application describes various improvements and further developments to the Expanded Bed Adsorption (EBA) technology. In particular, the application describes an EBA process where...
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6620625 |
Ultra high throughput sampling and analysis systems and methods
Ultra-high throughput systems and methods are used for sampling large numbers of different materials from surfaces of substantially planar library storage components. The systems and methods...
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6616846 |
Extraction of phosphonates
Glyphosate and other phosphonates including the bone resorption-inhibiting bisphosphonates are extracted from samples using immobilized forms of zinc, including zinc methacrylate polymers. The...
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6613234 |
Large pore volume composite mineral oxide beads, their preparation and their applications for adsorption and chromatography
The present invention provides porous mineral oxide beads which have large pore volumes and enhanced stability. The beads are based on a tetravalent metal oxide, such as zirconia, titania or...
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6613224 |
Liquid separation column smart cartridge
A LC column cartridge comprising a memory component integrally attached to it at the time of its manufacture, as well as a method for producing such a LC column cartridge with an integral memory...
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6613235 |
Method of detecting sample ions by continuous electrochemical regeneration of a stationary phase
An apparatus and method for electrochemically modifying the retention of a species on a chromatography material is disclosed. The apparatus comprises a housing having an effluent flow channel...
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6610208 |
Device for reducing loss of liquid during fraction collection
Spillage of liquid during switching of receptacles in a fraction collector is avoided by introducing a device in the flow path between an inlet tube and a dispensing means. The device includes an...
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