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6949186 Polar silanes and their use on silica supports  
A modified silica support having a polar phase bound to its surface and suitable for use for chromatographic separations, having the following formula: wherein, m=0-20; n=0-20; p=1-50; X is...
6946070 Composite matrices with interstitial polymer networks  
The present invention relates in general to the preparation and use of matrices having solid spaces, interstitial spaces and interstitial polymer networks. In particular, the interstitial polymer...
6946075 Purification of biological substances  
A process and apparatus for purifying one or more target substances from a source liquid, employing one or more cross-flow filter elements, and one or more types of chromatography resins, in...
6942793 Liquid chromatograph mass spectrometer  
A liquid chromatograph mass spectrometer comprises: a pump; a sample injector; a plurality of separation columns, including a first separation column and a second separation column; and mass...
6942802 Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography  
The present invention relates to the purification of polypeptides and the removal of endotoxin via immobilized metal affinity chromatography (IMAC). More specifically, the invention relates to...
6942794 High velocity chromatography column flow distributor  
The present invention is a flow distributor and integral bed support for a chromatography column. The flow distributor has an outlet extending through it and a bottom face across which is secured a...
6942792 Mixer for liquid chromatograph  
Three metal plate materials, each having penetration holes, are united together in this order as a set at such positions that penetration holes can penetrate through the three metal plate materials...
6939715 Method for producing purified hematinic iron-saccharidic complex and product produced  
A method for separating and purifying the active hematinic species present in iron-saccharidic complexes including sodium ferric gluconate complex in sucrose, ferric hydroxide-sucrose complex and...
6936174 Method for controlling an evaporative light scattering detector which is coupled to a liquid chromatography column  
Method allowing control of an evaporative light scattering detector which is coupled to a liquid chromatography column, substantially independently of the elution conditions for the chromatographic...
6936167 System and method for performing multiple parallel chromatographic separations  
Systems and methods for performing multiple parallel chromatographic separations are provided. Microfluidic cartridges containing multiple separation columns allow multiple separations to be...
6936165 Device for mounting an elongate element with axial clamping  
Device for mounting an elongated element with axial clamping, includes a body forming a support base whereon are fixed a stop part including a first support element for one end of the elongated...
6936166 Endpiece for a chromatography column  
A liquid transfer system ( 100 ) comprising a net ( 170 ) and a net support ( 160 ), wherein, the net ( 170 ) is integrally joined with the net support ( 160 ). The net ( 170 ) and the net support...
6932904 Chromatographic device and method of forming a chromatographic device  
A chromatographic device comprises a tube, a chromatographic medium, a piston assembly, and a locking mechanism. The tube comprises first and second opposite ends and an inner surface. The inner...
6929741 Column packaging for chromatography  
The present invention provides a packing for chromatography. Specifically, it provides a packing for chromatography in which a hydrophilic polymeric material is bound to the surface of a porous...
6926823 Polymer with superior polar retention for sample pretreatment  
A polymeric sorbent that can be employed in the extraction and purification of polar and nonpolar molecules from a complex media (e.g. pharmaceuticals from biological matrices) by solid phase...
6923916 Liquid chromatograph pump and control method therefor  
In a pump for feeding a liquid for chromatography, first and second plungers form first and second volumes respectively together with first and second chambers, the first plunger is prevented from...
6923907 Separation column devices and fabrication methods  
Pressure-driven microfluidic separation devices, such as may be used for performing high performance liquid chromatography, are provided. Multiple separation columns may be defined in a single...
6923908 Filter apparatus  
A filter apparatus for use in liquid chromatography systems includes a housing component having an open channel formed therethrough for operably receiving fluid transfer tubing in at least a first...
6919021 Simulated activity of Protein A displayed by ligands attached to a cellulose bead surface  
A method and compound for the purification of proteins including the attachment of a non-peptidic, small compound which simulates the affinity of Protein A for immumoglobulins to a support matrix....
6913697 Nanostructured separation and analysis devices for biological membranes  
The present invention provides a nanostructured device comprising a substrate including nanotroughs therein; and a lipid bilayer suspended on or supported in the substrate. A separation method is...
6913692 Rotating device for centrifugal partition chromatograph  
The rotating device for a centrifugal partition chromatograph comprises at least one thick-walled cylindrical body ( 1 ) that can be driven in rotation around its axis ( 14 ), the said cylindrical...
6913695 Sanitization of chromatographic media  
A method of sanitizing chromatographic media is provided. The method includes contacting the media with an acidic chaotropic agent, at low temperature and low pH. The method provides pathogen...
6911151 Device and method for the parallel separation of substances by liquid chromatography  
The invention relates to a device and a method for separating substances by liquid chromatography. The aim of the invention is to provide a device and a method by which means substances can be...
6908557 Collection system for chromatographic system  
The present invention provides a method and device for collecting and concentrating a desired compound from a chromatographic column exit stream. The collection chamber can be heated or cooled and...
6909091 Separation and analysis of sample components  
The invention describes a new integrated separation and analysis system for analysis and separation of at least one sample component, comprising a mass sensitive detector ( 1 ) with ionization...
6905595 Scalable liquid distribution system for large scale chromatography columns  
A uniform fluid distribution system ( 2 ) for use with a liquid transfer system ( 100 ) for maintaining an interface between liquid phases within a large scale separator system including a cell...
6896812 Process to compensate for a discrete non-separating section in simulated moving bed adsorptive separation processes  
Fluctuations, such as perturbations in the quality of the extract and/or raffinate streams removed from the circuit in a simulated moving bed (SMB) adsorptive process having at least one discrete...
6896797 Sample supply apparatus for simulated moving bed chromatographic device  
A simulated moving bed connected with a sample supply apparatus is constructed such that a sample liquid can be supplied continually to a simulated moving bed separation device without causing any...
6893569 Method and apparatus for high pressure liquid chromatography  
This modified HPLC instrument has the HPLC pump force only solvent through the serial flow line including a sampler, column, and detector; while buffer is discharged into the solvent from a syringe...
6887384 Monolithic microfluidic concentrators and mixers  
Microfluidic devices comprising porous monolithic polymer for concentration, extraction or mixing of fluids. A method for in situ preparation of monolithic polymers by in situ initiated...
6884345 Chromatography method and a column material useful in said method  
A novel sorbent suitable for use as a stationary phase in a chromatography column, the core of which consists of an organic polymer of synthetic or natural origin. Further, the carrier exhibits a...
6884346 Bonded phase photopolymerized sol-gel column and associated methods  
A separation column and a method of making the separation column are provided. The separation column includes a separation channel and a separation medium in the channel. The separation medium...
6881540 High throughtput screening of potential displacer molecules  
An effective technique for the high throughput screening of displacers is described. In this technique, potential displacers are employed to displace a biomolecule (e.g., protein) adsorbed on a...
6877363 Chromatography column  
The invention relates to a chromatography column for high-pressure liquid chromatography, which can be provided with different connection systems, such as a cartridge retaining device or a reducing...
6875348 Separation column having a photopolymerized sol-gel component and associated methods  
A separation column and a method of preparing the separation column are provided. The separation column includes a separation channel and a porous matrix in the channel. The porous matrix includes...
6875349 Method for fractionating a solution  
A method for fractionating a solution into two or more fractions by a chromatographic simulated moving bed (SMB) process, wherein the separation system comprises at least two separation profiles in...
6872314 Dewatering process  
Disclosed is a process for dewatering an organic compound other than a carboxylic acid using a simulated moving bed (SMB) containing a solid with different absorptivities for water and the organic...
6872302 Chromatographic apparatus  
An apparatus for pressurizing a removable chromatographic cartridge, comprises radial pressure means acting onto the side surface of the chromatographic cartridge, and axial pressure means acting...
6866786 Rapid characterization of polymers  
Methods and apparatus for characterizing a polymer sample and in preferred embodiments, libraries of polymer samples, in a comprehensive, directly-coupled multi-dimensional liquid chromatography...
6866785 Photopolymerized sol-gel column and associated methods  
A separation column and a method of making the separation column are provided. The separation column includes a separation channel and fritless separation medium in the channel. The separation...
6863820 Monolithic sorbents with fibre-reinforced plastic coating  
The invention relates to monolithic sorbents with a casing of fiber-reinforced plastic. Through the use of fiber-reinforced plastic having a viscosity of between 40 and 100 ml/10 min by the MVI...
6863824 Chromatography method and device with recovery of solvent  
A method and device for chromatographic separation producing at least two fractions are provided, in which: (i) the solvent is at least partially evaporated from the fractions produced; (ii) the...
6858842 Electrospray nozzle and monolithic substrate  
An electrospray nozzle system is disclosed. The electrospray portion of the device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice...
6858135 Hydrophilic monolithic columns for separation of saccharide mixtures  
Polar, monolithic CEC columns having an amine and/or cyano functional stationary phase are used to separate complex mixtures of saccharides. Using the positive-ion mode of detection for neutral...
6858435 Method and system for peak parking in liquid chromatography-mass spectrometer (LC-MS) analysis  
A reconfigurable multi-mode post-column analysis system improves resolution of liquid chromatography detection data by providing a parking or MS/MS detection mode in which flow of column eluent is...
6855258 Methods for characterization of polymers using multi-dimensional liquid chromatography with parallel second-dimension sampling  
Methods and apparatus for characterizing a polymer sample and in preferred embodiments, libraries of polymer samples, in a comprehensive, directly-coupled multi-dimensional liquid chromatography...
6855251 Microfabricated electrospray device  
An electrospray device is disclosed. The electrospray device comprises a substrate defining a channel between an entrance orifice on an injection surface and an exit orifice on an ejection surface,...
6852230 Method for the manufacture of compositions containing low concentrations of salts  
Method for desalting an aqueous liquid containing a charged substance comprising the steps of: (i) contacting liquid (I) with an ion-exchanger (1) under conditions permitting binding between...
6846410 High stability porous metal oxide spherules used for one-step antibody purifications  
The present invention describes the use of porous metal oxides for the preparative purification of antibodies and biomolecules within a range of particle physical characteristics. Typically,...
6841073 Reversed-phase liquid chromatography, liquid chromatograph apparatus, and column  
A reversed-phase liquid chromatography using a mobile phase containing water as a main component thereof, wherein in a measurement after a flow of the mobile phase through a column is temporarily...