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7402229 Fabrication and use of semipermeable membranes and gels for the control of electrolysis in a microfluidic device  
A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first...
7381317 Methods and compositions for capillary electrophoresis (CE)  
This invention relates to improved methods and compositions for conducting Capillary Electrophoresis (CE) to separate molecules on the basis of their respective size or charge.
7316770 Method of electrophoresis, electrophoresis apparatus and capillary array  
A method of electrophoresis, an electrophoresis apparatus and a capillary array in which a fluorescently labelled sample is supplied into capillaries in a capillary array constituted by a plurality...
7314550 Analytical separations with polyelectrolyte layers, molecular micelles, or zwitterionic polymers  
Polymeric surfactants (molecular micelles) are disclosed for use in open tubular capillary electrochromatography or in high performance liquid chromatography. For example, fused silica capillaries...
7309409 Multi-channel bio-separation cartridge  
A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir....
7294247 Electrophoretic separating device and method for using the device  
The invention concerns to an electrophoretic separation device comprising a separation channel having at least one in- and outlet opening at the beginning and at the end of the channel and one...
7223326 Capillary electrophoresis system  
A capillary electrophoresis system includes a plurality of capillaries arranged in parallel on a vertical plane at an identical distance from each other, each of which has a sample injection end...
7217352 Capillary electrophoresis device  
An electrophoresis device is disclosed that is capable of reducing waves occurring in a fluid in which the capillary tips of a capillary assay are immersed. A plurality of partition plate members...
7208072 Multi-segment cartridge for bio-separation with multiplexed fluorescence detection  
A bio-separation instrument using a multi-segment cartridge. The cartridge includes a plurality of efficient, compact, portable, interchangeable, reusable, recyclable, modular, multi-channel...
7195698 Capillary electrophoretic apparatus, sample plate and sample injection method  
An electrode plate of a sample plate is set on the body of an electrophoretic apparatus, while a plug is inserted into a migration high voltage line connection hole and connected to a high-tension...
7179357 Serial sample injection in capillary electrophoresis  
The invention is a method of performing electrophoresis that increases sample throughput and increases the efficiency and speed of the analysis of polynucleotides by electrophoresis. The method is...
7169277 High throughput separations based analysis systems  
Devices, systems and methods for use in separating sample materials into different fractions that employ bulk fluid flow for loading of samples followed by electrophoretic separation of the sample...
7163610 Conductive media for electrophoresis  
A series of low molarity conductive media based on non-buffering univalent cations, such as sodium chloride-sodium acetate (SCA), sodium boric acid (SB), lithium boric acid, and lithium acetate...
7156969 Microfluidic matrix localization apparatus and methods  
Multiphasic microfluidic apparatus for performing product fluid manipulation and separation in a single continuous unit are provided. Related methods, kits, and compositions are also provided.
7153403 Protein market pellets and method of making and using the same  
A protein marker pellet for use in a gel electrophoresis system includes one or more protein markers including a protein of known molecular weight with ionic components to provide electrical...
7147764 Dual electrode injection of analyte into a capillary electrophoretic device  
An injection system including a first electrical circuit for concentration of an analyte and a second electrical circuit for injection of the concentrated analyte into an electrophoretic device is...
7135144 Method for the manipulation of a fluid sample  
The invention provides a device and method for the manipulation of materials (e.g., particles, cells, macromolecules, such as proteins, nucleic acids or other moieties) in a fluid sample. The...
7083711 Capillary electrophoresis gel especially for separation made for single stranded nucleic acid separations  
A separation matrix for capillary electrophoresis of single-stranded nucleic acids is disclosed. The matrix comprises an aqueous buffer containing a denaturant and (hydroxypropyl)methyl cellulose.
7081191 Capillary electrophoresis device  
The capillary electrophoresis device using one pressure-resistant syringe ( 125 ) is capable of automatically suctioning in polymer solution and injecting polymer solution into a capillary array (...
7081190 Methods and compositions for performing molecular separations  
The present invention provides methods of electrophoretically separating macromolecular species, as well as compositions and systems useful in carrying out such methods. Specifically, the methods...
7059352 Triggerable passive valve for use in controlling the flow of fluid  
The present invention is directed to valves for use in controlling the flow of fluid and, more particularly, to a triggerable passive valve for use in controlling the flow of fluid. In one...
7041208 Microfluidic devices and methods for two-dimensional separations  
A microfluidic device includes first and second substrates and a microfluidic cavity formed in one of the first and second substrates. The microfluidic cavity has a width (W) and a depth (D),...
7018520 Concentration and cleanup of nucleic acid samples  
Methods and devices are described for concentration and cleanup of samples containing bio-molecule analytes (e.g., polynucleotides, such as DNA, RNA, PNA). Various embodiments provide for...
6998251 Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics  
Reactors and methods for miniaturized reactions having enhanced reaction kinetics. In particular the subject matter is directed to chemical and biological reactions conducted in a nanoporous...
6991713 Methods and apparatus for processing a sample of biomolecular analyte using a microfabricated device  
A technique processes a sample of biomolecular analyte. The technique uses an apparatus having a support assembly that receives and supports a test module, a load assembly that loads the sample of...
6942778 Microstructure apparatus and method for separating differently charged molecules using an applied electric field  
The field of the present invention relates generally to a microstructure apparatus which may be used in a high-throughput screening context to monitor the rate of reaction of an enzyme with its...
6926815 Copolymers for capillary gel electrophoresis  
This invention relates to an electrophoresis separation medium having a gel matrix of at least one random, linear copolymer comprising a primary comonomer and at least one secondary comonomer,...
6908594 Efficient microfluidic sealing  
Improved sealing for microstructures in microfluidic devices having a plurality of units is provided by providing collars surrounding the openings to the microstructures, such as reservoirs. The...
6878255 Microfluidic devices with thick-film electrochemical detection  
An apparatus for conducting a microfluidic process and analysis, including at least one elongated microfluidic channel, fluidic transport means for transport of fluids through the microfluidic...
6878254 Size separation of analytes using monomeric surfactants  
A sieving medium for use in the separation of analytes in a sample containing at least one such analyte comprises a monomeric non-ionic surfactant of the of the general formula, B-A, wherein A is a...
6837977 Capillary electrophoresis method for screening for affinity ligands using a detectable competitive ligand  
The invention relates to a capillary electrophoresis-based method of screening complex materials for any unidentified affinity ligand that binds to a target of interest. The method subjects a plug...
6830670 Heat-sensitive medium for separating species in a separating channel and use thereof  
A medium comprises an electrolyte wherein is dissolved at least an assembly of block copolymers characterized in that the block copolymers: are present in the electrolyte at a concentration level...
6805784 Capillary array  
The structure of a capillary head section is made such that the liquid contacting surfaces of a capillary holder, a capillary, and an adhesive form a plane surface, and this shared liquid...
6787016 Dynamic coating with linear polymer mixture for electrophoresis  
Compositions and methods are provided for performing capillary electrophoresis using a composition comprising in combination in an aqueous buffered medium a coating polymer and a sieving polymer,...
6783992 Methods and using chemico-mechanical microvalve devices for the selective separation of components from multi-component fluid samples  
Methods for selectively separating at least one component from a multi-component componant fluidic sample are provided. In the subject methods, the fluidic sample is introduced into a micro-fluidic...
6660148 Electrophoretic method and electrophoretic instrument therefor  
An injection syringe 14 for injecting a gel into a capillary 111, a charging syringe 15 for charging the injection syringe 14 with the gel 10 are attached to a block 17. A check valve 16 is...
6660147 High density electrophoresis device and method  
The present invention provides, in one aspect, an apparatus for electrophoretic separation of analytes. In one aspect, the apparatus comprises a disc-shaped substrate defining (1) a central...
6616825 Electrochromatographic device for use in enantioselective separation, and enantioselective separation medium for use therein  
An electrochromatographic device is provided for conducting enantioselective separation of enantiomers. The device is comprised of a conduit containing a monolithic enantioselective separation...
6610186 Method and device for separating particles or molecules by migration through a ferrofluid  
The invention concerns a method for separating particles or molecules whereby these particles or molecules are introduced in a separating medium and a moving force is applied to them in said...
6602391 Apparatus and method for combined capillary separation and blotting of biological macromolecules  
An apparatus and method are described for capillary separation of macromolecules and precise post-separation blotting. Apparatus include disposable separating element (capillary), which contains a...
6576104 Apparatus and method for reading gel electrophoresis pattern  
An apparatus and a method for reading a gel electrophoresis pattern can read the gel electrophoresis pattern of a sample, such as a nucleic acid and a protein, with high sensitivity and without...
6562213 Electrophoresis apparatus for simultaneous loading of multiple samples  
Apparatus for simultaneous loading of multiple samples for molecular separation, including a separation area with walls, at least one of the walls has apertures having loading sites, a gel located...
6524866 Capillary electrophoretic method to detect target-binding ligands and to determine their relative affinities  
The invention relates to capillary electrophoretic methods for detecting ligands or hit compounds that can bind to a selected target at or above a selected binding strength. The method allows one...
RE37941 Capillary electrophoresis using replaceable gels  
The filling of an internally coated capillary with a gel in its polymerized state without damaging the gel. The coating prevents bonding of the gel to the inside of the capillary, The gel comprises...
6475364 Methods, devices and systems for characterizing proteins  
A method of characterizing a polypeptide, comprising providing a first capillary channel having a separation buffer disposed within, wherein the separation buffer comprises a non-crosslinked...
6475361 Capillary electrophoresis apparatus having filling/refilling system and methods for use thereof  
The present invention relates to an electrophoresis apparatus having a filling/refilling system and methods of using the same. The electrophoresis apparatus comprises a first buffer chamber...
6461492 Capillary electrophoretic apparatus  
A multi-capillary electrophoresis apparatus arranged with a fixed sample injection holder opposite a detection side holder within the same plane and an epi-optical detection system. A sample is...
6440284 Methods and compositions for performing molecular separations  
The present invention provides methods of electrophoretically separating macromolecular species, as well as compositions and systems useful in carrying out such methods. Specifically, the methods...
6432290 Apparatus and method for trapping bead based reagents within microfluidic analysis systems  
The present invention provides an on-chip packed reactor bed design that allows for an effective exchange of packing materials such as beads at a miniaturized level. The present invention extends...
6428670 Gel charger for capillary column  
A holder for a capillary cassette closes a chamber, and is fixed to a detection side holder fixing member. An acidic solution container, an alkaline solution container, a pure water container and a...
Matches 1 - 50 out of 153 1 2 3 4 >