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8986530 Sample analysis systems, devices, and associated methods of operation  
Embodiments of analysis systems, electrophoresis devices, and associated methods of analysis are described herein. In one embodiment, a method of analyzing a sample containing an electrolyte...
8968540 Trans-base tunnel reader for sequencing  
A device for reading the sequence of a polymer, consisting of a first electrode and a second electrode, each electrode being functionalized with a reader molecule strongly bonded to the...
8968678 Microfluidic detection of analytes  
An apparatus and methods for concentrating samples for application to microfluidic devices are disclosed. The methods involve electrophoresing charged molecules from a high volume sample into a...
8961757 Nanopore and carbon nanotube based DNA sequencer  
The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon...
8961765 Plastic microfluidic separation and detection platforms  
Plastic electrophoresis separation chips are provided comprising a plurality of microfluidic channels and a detection window, where the detection window comprises a thin plastic; and the detection...
8961764 Micro fluidic optic design  
A DNA analyzer includes an interface for coupling a microfluidic chip to the DNA analyzer. The microfluidic chip includes a first separation channel for electrophoretic separation of DNA fragments...
8926905 Optical lens system and method for microfluidic devices  
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic...
8926813 Devices and methods for determining the length of biopolymers and distances between probes bound thereto  
Devices and methods for detecting the length of analytes, and/or sequencing analytes are provided in which two or more electrical signals are obtained as an analyte traverses a fluidic channel....
8882980 Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels  
Devices and methods for detecting an analyte are provided. Devices for voltage sensing of analytes may comprise a fluidic channel defined in a substrate, a pair of sensing electrodes disposed in a...
8858770 Plastic microfluidic separation and detection platforms  
Plastic electrophoresis separation chips are provided comprising a plurality of microfluidic channels and a detection window, where the detection window comprises a thin plastic; and the detection...
8828211 Nanopore device with graphene supported artificial lipid membrane  
The invention features the use of graphene, a one atom thick planar sheet of bonded carbon atoms, in the formation of artificial lipid membranes. The invention also features the use of these...
8815069 Disposable capillary electrophoresis detecting device  
A disposable capillary electrophoresis detecting device includes a fixing device, a capillary electrophoresis microchip, and an electrochemical sensor microchip. The fixing device includes two...
8771491 Ultrafast sequencing of biological polymers using a labeled nanopore  
Methods and systems for sequencing a biological molecule or polymer, e.g., a nucleic acid, are provided. One or more donor labels, which are attached to a pore or nanopore, may be illuminated or...
8728292 Apparatus for the measurement of a concentration of a charged species in a sample  
An apparatus (1) for the measurement of a concentration of a charged species in a sample (10) is disclosed. The sample (10) comprises a plurality of types of charged species and at least one...
8721859 Analysis apparatus and analysis method  
An analysis apparatus is an apparatus that performs electrophoresis using a microchip provided with a channel. The analysis apparatus includes a cooling unit (an electron cooling element and a...
8721968 Optical lens system and method for microfluidic devices  
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic...
8702949 Capillary electrophoresis apparatus  
The solution reservoir apparatus of the capillary electrophoresis apparatus securely affixes an evaporation-preventing membrane to a container when a capillary is inserted or withdrawn, without...
8685343 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Microfluidic detection of analytes
 
An apparatus and methods for concentrating samples for application to microfluidic devices are disclosed. The methods involve electrophoresing charged molecules from a high volume sample into a...
8685326 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Optical lens system and method for microfluidic devices
 
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic...
8685220 Capillary electrophoresis apparatus  
The invention provides a capillary electrophoresis apparatus which can improve the operability and measuring speed. According to the invention, a sensor for identifying the type of sample...
RE44711 Optoelectronic tweezers for microparticle and cell manipulation  
An optical image-driven light induced dielectrophoresis (DEP) apparatus and method are described which provide for the manipulation of particles or cells with a diameter on the order of 100 μm or...
8628649 Nanopore and carbon nanotube based DNA sequencer and a serial recognition sequencer  
The present invention is directed to systems, devices and methods for identifying biopolymers, such as strands of DNA, as they pass through a constriction such as a carbon nanotube nanopore. More...
8617374 Capillary electrophoresis using clear coated capillary tubes  
A capillary tube having a hard, optically clear external coating or cladding. In one embodiment, the external clear coating comprises hard-fluoropolymer. The hard-fluoropolymer coating bonds to...
8597485 Optical detection alignment coupling apparatus  
An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical...
8512640 Optical lens system and method for microfluidic devices  
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic...
8500982 Compositions, devices, systems, and methods for using a nanopore  
The invention herein disclosed provides for devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a...
8486247 Use of microfluidic systems in the electrochemical detection of target analytes  
The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes.
8414755 Microfluidic separation device  
A microfluidic separation device is provided that includes a sample channel having a first sample channel region and a second sample channel region, where a cross-section of the first sample...
8404092 Method for the reduction of cross talk in multiplex capillary electrophoresis  
The invention is a high-throughput multi-capillary system utilizing a 2-dimensional mask onto which the detection windows of the capillaries are lined up in alternating columns and rows. The image...
8357281 Multi-wavelength fluorescence detection system for multiplexed capillary electrophoresis  
Using multiple dichroics mirrors to split and redirect different wavelength regions of light in a multi-wavelength fluorescence detection system.
8313698 Droplet-based nucleic acid amplification apparatus and system  
The present invention relates to a droplet-based nucleic acid amplification apparatus and system. According to one embodiment, a droplet microactuator is provided made using a first substrate...
8293088 Direct determination of carbohydrates, amino acids and antibiotics by microchip electrophoresis with pulsed amperometric detection  
The present invention provides a microchip for performing electrophoresis with pulsed amperometric detection (PAD) for the separation and detection of underivatized carbohydrates, amino acids,...
8268249 Analytical device with lightguide illumination of capillary and microgroove arrays  
An analytical cell including a lightguide with a plurality of conduits filled with a migration medium. The medium, the lightguide and a surrounding medium have refractive indices selected such...
8262888 Capillary electrophoresis apparatus  
There is provided a capillary electrophoresis apparatus wherein coupling efficiency of exciting irradiation light to a capillary array does not decline even if any one capillary array of two...
8263022 Microfluidic detection of analytes  
An apparatus and methods for concentrating samples for application to microfluidic devices are disclosed. The methods involve electrophoresing charged molecules from a high volume sample into a...
8257569 Capillary array unit and capillary electrophoresis apparatus  
In a capillary electrophoresis apparatus, a capillary array unit has a capillary array including capillaries having a capillary head and a detection unit, a frame for supporting the capillary...
8252163 Analysis apparatus for capillary electrophoresis  
A capillary electrophoresis analysis apparatus is provided for analyzing samples by a capillary electrophoresis method that allows for rapid and highly accurate separation and detection.
8252162 Capillary electrophoresis apparatus  
The invention provides a capillary electrophoresis apparatus which can improve the operability and measuring speed. According to the invention, a sensor for identifying the type of sample...
8246803 Capillary electrophoresis apparatus and electrophoresis method  
An object of the present invention is to provide a capillary electrophoresis apparatus in which simultaneity can be ensured between sensitivity and data acquisition to decrease a pull-up signal...
8246806 Multi-capillary array electrophoresis device  
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than...
8206568 Material deposition techniques for control of solid state aperture surface properties  
The invention provides a method for molecular analysis. In the method, sidewalls are formed extending through a structure between two structure surfaces, to define an aperture. A layer of material...
8187541 Apparatus for detecting target molecules and related methods  
An apparatus for analysis of a sample and in particular of a biological sample. The apparatus contains a microfluidic chip with dies, adapted to be selectively activated or deactivated by presence...
8182746 Electrophoresis process using a valve system  
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus...
8163151 Assays for detection of Von Willebrand factor (vWF) multimers and for degradation of vWF by agents such as Adamts13 and related methods  
Methods of analyzing the electrophoretic mobility distribution of von Willebrand factor (vWF) multimers include providing a sample medium comprising a plurality vWF multimers. The vWF multimers...
8142635 Capillary array  
A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis,...
8048378 Optical lens system and method for microfluidic devices  
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic...
8043493 Multi-capillary array electrophoresis device  
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than...
8030092 Controlled electrophoresis method  
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus...
8018593 Integrated nucleic acid analysis  
The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification,...
8012327 Capillary electrophoresis apparatus and electrophoresis method  
An object of the present invention is to provide a capillary electrophoresis apparatus in which simultaneity can be ensured between sensitivity and data acquisition to decrease a pull-up signal...

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