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7612355 |
Optoelectronic tweezers for microparticle and cell manipulation
An optical image-driven light induced dielectrophoresis (DEP) apparatus and method are described which provide for the manipulation of particles or cells with a diameter on the order of 100 μm or...
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7588672 |
Optical lens system and method for microfluidic devices
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic...
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7578915 |
Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis
A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or...
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7540949 |
Capillary array electrophoresis apparatus and method of separating and analyzing specimen
At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays...
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7534335 |
Multiplexed, absorbance-based capillary electrophoresis system and method
A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a...
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7528369 |
Charged droplet spray probe
An improved sample introduction probe is disclosed for the production of ions from liquid sample solutions in an electrospray ion source. Nebulization of a liquid sample emerging from the end of an...
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7513984 |
Capillary array electrophoresis apparatus
When irradiating laser beam from the side face of the capillary array, an optical axis of the laser beam is inclined in vertical direction with respect to a plane face formed by the capillary...
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7497937 |
Microfabricated chip and method of use
A multiplexed, absorbance-based microfabricated chip electrophoresis system, microfabricated chip, and method of use are included for the detection and identification of protein species. The...
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7497934 |
System and method
An analysis system for and method of enabling determination of the velocities of migrating objects and also classifying migrating objects into groups having a common constraint. In one aspect the...
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7473893 |
ICP/ESI mass spectrometry systems and methods of use thereof
Briefly described, embodiments of this disclosure include mass spectrometry systems and methods of performing molecular mass spectrometry and elemental mass spectrometry using a single mass...
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7459070 |
Automated parallel capillary electrophoresis system with hydrodynamic sample injection
An automated capillary zone electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends...
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7459068 |
Multi-capillary electrophoresis apparatus
A multi-capillary electrophoresis apparatus is provided for reducing errors during analysis caused by fluctuations in electrophoresis time among plural capillaries of the apparatus. The...
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7452507 |
Portable apparatus for separating sample and detecting target analytes
Portable devices and methods for determining the presence of a target analyte using a portable device are provided. The portable device is preferably hand-held. A sample is injected to the portable...
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7449097 |
Electrophoretic mobility measuring apparatus
The present invention provides an electrophoretic mobility measuring apparatus capable of conducting measurement with high sensitivity with optical attenuation reduced by incidence of light through...
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7445701 |
Capillary array unit and electrophoresis based thereon
A capillary array includes multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of...
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7439075 |
Method and device for withdrawing suspended microparticles from a fluidic microsystem
A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem ( 10 ) is described, whereby the fluid flow converges with at least one output flow to form a discharge...
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7438792 |
Separation system with a sheath-flow supported electrochemical detector
An electrochemical detector including side channels associated with a separation channel of a sample component separation apparatus is provided. The side channels of the detector, in one...
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7422672 |
Capillary array apparatus, method of manufacturing the same, and electrophoresis analysis method
An electrophoresis analysis method and apparatus capable of maintaining high reliability upon a repeated use of the same gel. A heat transfer medium selected from the group consisting of solids,...
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7419578 |
Capillary electrophoresis apparatus
A capillary array electrophoresis which can measure fluorescence of a number of capillaries at a time with high sensitivity and can automatically analyze a sample sequentially. An end edge as a...
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7419577 |
Removal method for coating of polymer coated glass capillary tubing and polymer coated glass capillary tubing
The present invention provides a method for producing a high-quality capillary tube used in an electrophoresis apparatus in a safe and inexpensive manner. A polymer coating on a capillary tube is...
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7419576 |
Analyzing apparatus
One of the principal objects of the present invention is to realize, in a small scale and at a low cost, an analyzing apparatus that analyzes and manipulates a minute sample such as DNA. The...
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7417418 |
Thin film sensor
An electrically operated, particle detecting, or characterizing, sensor structured as a thin film multilayer sandwich. Three or more electrodes are deposited onto thin layers of film, and stacked...
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7384527 |
Electrophoresis apparatus and a plate therefor
The invention provides an electrophoresis apparatus comprising an electrophoretic chamber containing at least on two-plate housing for a sieving matrix, each said at least one two-plate housing...
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7361259 |
Capillary array and electrophoresis apparatus, and method
A capillary electrophoresis device including a capillary array, and a method of manufacturing the capillary array, are provided. During the manufacture of the capillary array, a plurality of...
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7344628 |
Capillary electrophoresis-electrochemical detection microchip device and supporting circuits
The present invention is a capillary electrophoresis device, comprising a substrate; a first channel in the substrate, and having a buffer arm and a detection arm; a second channel in the substrate...
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7329333 |
Uniform laser excitation and detection in capillary array electrophoresis system and method
A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is...
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7309409 |
Multi-channel bio-separation cartridge
A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir....
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7307802 |
Optical lens system and method for microfluidic devices
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic...
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7258775 |
Method and device for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body
The invention relates to a method for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body. The proteins...
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7250099 |
Optical detection alignment coupling apparatus
An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical blocks...
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7250098 |
Multi-capillary array electrophoresis device
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than...
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7223326 |
Capillary electrophoresis system
A capillary electrophoresis system includes a plurality of capillaries arranged in parallel on a vertical plane at an identical distance from each other, each of which has a sample injection end...
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7217352 |
Capillary electrophoresis device
An electrophoresis device is disclosed that is capable of reducing waves occurring in a fluid in which the capillary tips of a capillary assay are immersed. A plurality of partition plate members...
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7217350 |
Mobility and effects arising from surface charge
A method of, and apparatus for, automatically determining an electric charge—related characteristic or derived parameter of particles in a dispersion or of a cell wall, comprises having a...
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7208072 |
Multi-segment cartridge for bio-separation with multiplexed fluorescence detection
A bio-separation instrument using a multi-segment cartridge. The cartridge includes a plurality of efficient, compact, portable, interchangeable, reusable, recyclable, modular, multi-channel...
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7195699 |
Electrophoresis member, production thereof and capillary electrophoresis apparatus
An electrophoresis member is produced by laying a plurality of capillaries on an adhesive layer born on a support layer to form a capillary layer, laminating thereon a second support layer, and...
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7161356 |
Voltage/current testing equipment for microfluidic devices
The present invention provides novel methods and devices for testing/verifying the configuration of one or more microfluidic elements in a microfluidic device. In particular the methods and devices...
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7125478 |
Microscale electrophoresis devices for biomolecule separation and detection
The present invention relates to microfabrication and utilization of microscale electrophoresis devices as well as the separation and detection of biomolecules in microscale electrophoresis...
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7118711 |
Microcolumn reactor
The invention relates to a microcolumn reactor for carrying out reactions on solid phases and/or with biological cells. The aim of the invention is to provide a microcolumn reactor for processes of...
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7118662 |
Electrophoresis apparatus
The windows 5 a, 5 b are configured so that the thickness of the upper and lower parts of the substrate formed therein with the channels becomes thinner in these parts than in other parts. An...
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7118660 |
Method and apparatus for analyzing a mixture of sample substances
An apparatus for analyzing a mixture of sample substances comprises a fluid-guiding structure wherein the sample substances are moving essentially in one dimension along the structure and are...
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7112266 |
Multi channel capillary electrophoresis device and method
Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein...
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7108775 |
Apparatus and method for confining eluted samples in electrophoresis systems
The present teachings provide a microfluidic apparatus comprising a body defining at least one channel that extends through said body, the channel including an inlet and an outlet; and an electrode...
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7090758 |
Capillary array electrophoresis scanner
An improved rotary confocal fluorescence scanner capable of detecting analytes separated on over a 1,000 capillaries simultaneously. This system uses a confocal microscope objective and mirror...
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7056427 |
Electrophoresis apparatus using capillary array and sample plate assembly used therefor
A sample plate assembly for an electrophoresis apparatus including a tray at a sample supply portion of a capillary array, an adapter for the tray, a sample plate mounted on the adapter, a septer...
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7054004 |
Capillary array and capillary array photodetector
A multi-focus capillary array that can reduce crosstalk and a capillary array photodetector are provided. On a substrate 20 on which a plurality of capillaries are aligned, a perforation 72 is...
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7037417 |
Mechanical control of fluids in micro-analytical devices
An apparatus for manipulating fluid samples comprises a micro-chip device having first and second covered channels, each channel having openings at both ends. The channels intersect to form a...
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7037416 |
Method for monitoring flow rate using fluorescent markers
Microfluidic methods, devices, and systems are provided for monitoring and controlling flow rates in response to one or more marker signals. The marker signals are used to provide an indication of...
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7033476 |
Separation and counting of single molecules through nanofluidics, programmable electrophoresis, and nanoelectrode-gated tunneling and dielectric detection
An apparatus for carrying out the separation, detection, and/or counting of single molecules at nanometer scale. Molecular separation is achieved by driving single molecules through a microfluidic...
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7033475 |
Electrophoretic apparatus
An electrophoretic apparatus which can analyze multiple tests specimens and being comprised of an electrophoretic member having a relatively simple configuration of passages, such that one or a...
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