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9034161 Sperm separation devices and associated methods  
The present invention provides methods, devices, and kits for separating and selecting top sperm from a sperm sample of a subject. In one aspect, for example, such a method can include removing a...
9034163 Electrode for capillary electrophoresis  
An electrode assembly for capillary electrophoresis (CE) comprises a manifold (310), a connector (305) a sheath (300), and a seal (325). A capillary tube (100) passes through the manifold, the...
8974650 Microfluidic system  
A method for forming a microfluidic channel with improved flow characteristics for one or more analytes is disclosed. A microfluidic channel having modified surfaces is formed in a glass layer or...
8969090 DNA sequencing methods and detectors and systems for carrying out the same  
In some embodiments, an analyte detection system is provided that includes a nanochannel, an electrode arrangement, and a plurality of nanoFET devices disposed in the nanochannel. A plurality of...
8969071 Passive chip-based droplet sorting  
An apparatus for passive sorting of microdroplets including a main flow channel, a flow stream of microdroplets in the main flow channel wherein the microdroplets have substantially the same...
8968545 Apparatus and method for molecular separation, purification, and sensing  
Described are devices and methods for forming one or more nanomembranes including electroactive nanomembranes within a nanowell or nanotube, or combinations thereof, in a support material....
8968539 Methods for voltage-induced protein incorporation into planar lipid bilayers  
Disclosed here are methods useful for incorporating protein into lipid bilayers using voltage induced insertion. The methods presented herein can decrease time and costs associated with...
8968873 Co-flow microfluidic device for polymersome formation  
A microfluidic device to produce polymersomes having three coaxial passageways of increasing size with fluid flowing in one direction. The first and smallest passageway contains the content of the...
8940147 Microfluidic hubs, systems, and methods for interface fluidic modules  
Embodiments of microfluidic hubs and systems are described that may be used to connect fluidic modules. A space between surfaces may be set by fixtures described herein. In some examples a fixture...
8940146 Device for electro membrane extraction  
A device for electro membrane extraction has a syringe holder adapted to hold a syringe having an acceptor solution, and a sample vial holder adapted to hold a sample vial having a vial cap, where...
8912252 Film-forming pigments and coating system including the same  
A coated pigment that includes polymer encapsulations which act as a pigment dispersant and film forming agent, coating systems that include the coated pigment and methods for producing the coated...
8906322 Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields  
The present invention relates to methods and devices for separating particles according to size. More specifically, the present invention relates to a microfluidic method and device for the...
8888980 Electrophoresis apparatus and control method thereof  
An electrophoresis apparatus that applies voltage from electrodes that are provided in a capillary flow channel and causes component separation by performing electrophoresis on a specimen that is...
8883513 Droplet-based particle sorting  
The present invention relates to droplet-based particle sorting. According to one embodiment, a droplet microactuator is provided and includes: (a) a suspension of particles; and (b) electrodes...
8871072 Flow step focusing  
Flow step focusing isolates and concentrates a molecule of interest by flowing a liquid comprising a molecule of interest through a main channel having an inlet and an outlet with application of a...
8859211 Immunodisplacement electrophoresis  
The disclosure teaches a method for the analysis of a sample by electrophoresis, making use of a binding partner for a target compound or group of target compounds which may be present in the...
8834694 Dry compositions and methods for gel electrophoresis  
The invention provides dry compositions for preparing and loading a sample on a gel for electrophoretic separation. The dry compositions preferably include a tracking dye and a sedimenting agent...
8834696 Amplified electrokinetic fluid pumping switching and desalting  
The present invention provides a device and methods of use thereof for desalting a solution. The methods, inter-alia, make use of a device comprising microchannels, which are linked to conduits,...
8828209 Massively parallel 2-dimensional capillary electrophoresis  
This invention discloses a highly efficient method, system and apparatus for nucleic acid analysis, including sequencing (both automated re-sequencing and de-novo sequencing). The system is...
8821702 Devices and methods for electroosmotic transport of non-polar solvents  
A microdevice for supporting a flowing nonpolar fluid is disclosed. The microdevice includes a substrate that is at least partially coated by one or more amphiphilic layers. Methods for using the...
8795500 Apparatus and microchip for sorting micro particles  
In one example embodiment, a micro-particle sorting apparatus includes: (a) a microchip in which a flow path through which liquid containing a micro particle flows and an orifice through which the...
8795605 Apparatus and methods for transferring materials between locations possessing different cross-sectional areas with minimal band spreading and dispersion due to unequal path-lengths  
Non-limiting exemplary embodiment(s) of apparatus(es) and method(s) are described for the conveyance of fluid media and entrained materials between two or more locations, each possessing a...
8784631 Separation medium for capillary electrophoresis suppressing electroosmotic flow in bare capillaries and channels  
Disclosed herein is a composition of a separation medium and method of its use for electrophoresis in bare channels, either capillaries or chips, with suppressed electroosmotic flow, wherein...
8784626 Bio-analysis using ball-ended incident and output optical fibers  
A detection optics configuration for bio-analysis, in which the direction of incident radiation, the axis of the separation channel, and the direction of collection of the output radiation are...
8778155 Disposible bio-analysis cartridge and instrument for conducting bio-analysis using same  
A cartridge-based bio-separation system configured to utilize a pen shaped bio-separation cartridge that is easy to assemble and use with no moving parts and that has an integrated reagent...
8758587 Analysis apparatus and analysis method  
An analysis apparatus is provided with a storage tank, an injection nozzle, a syringe, a collection nozzle, a test sample tank, a microchip having two or more separation channels, detectors, a...
8728292 Apparatus for the measurement of a concentration of a charged species in a sample  
An apparatus (1) for the measurement of a concentration of a charged species in a sample (10) is disclosed. The sample (10) comprises a plurality of types of charged species and at least one...
8715478 Electrically controlled ion transport device  
A device for electrically controlled transport of ions between a source and a target electrolyte, including: a first source electrode and a first target electrode, each capable of conducting ions...
8715475 Microfluidic device for separating, fractionating, or preconcentrating analytes contained in an electrolyte  
A microfluidic device for separating, fractionating, or preconcentrating analytes contained in an electrolyte having at least two reservoirs separated by at least one microchannel and/or...
8702941 Method of analyzing hemoglobin by electrophoresis  
A method for analyzing hemoglobin by electrophoresis, capable of analyzing hemoglobin A1c (HbA1c) and modified hemoglobin with improved accuracy in a shortened analysis time is provided. The...
8685220 Capillary electrophoresis apparatus  
The invention provides a capillary electrophoresis apparatus which can improve the operability and measuring speed. According to the invention, a sensor for identifying the type of sample...
8685219 Apparatus for capillary electrophoresis with polyelectrolyte multilayer coating on the capillary walls  
An apparatus for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage...
8641882 Capillary column cartridge  
Described is a capillary column cartridge. The cartridge can be used to perform separations according to various techniques such as capillary gas chromatography, capillary electrophoresis and...
8613845 Self contained capillary electrophoresis system for interfacing with mass spectrometry  
A complete capillary electrophoresis (CE) system that is capable of providing a continuous flow of effluent at the exit of the flow-through outlet vial is provided. A self-contained capillary...
8562805 Method of actuating and an actuator  
A method of actuating, comprising: filling at least a portion of a tube (21) with a liquid (19) containing electrolytes, the tube (21) having an inner surface that is electrically chargeable when...
8545686 Electrophoretic apparatus and electrophoretic method  
The present invention relates to detection of an emission spectrum by irradiating excitation light onto a plurality of electrophoretic paths and dispersing fluorescent light output from the...
8545771 Fluidic devices having incorporated electrodes  
The invention provides fluidic devices having incorporated electrodes. One device comprises a card and first and second caddy segments. The first caddy segment comprises first and second...
8535500 Surface acoustic wave sensor device including target biomolecule isolation component  
Provided herein is a surface acoustic wave (“SAW”) sensor device including an isolation component of a target biomolecule. A sample containing the target biomolecule is separated by its size using...
8529760 Optical separator and method for separating particles suspended in a fluid  
A device and method of using same, wherein the device includes a collimated light source operable to generate a collimated light source beam, the collimated light source beam comprising a beam...
8519014 Ion exchangeable mixture and method of producing the same  
An ion exchangeable mixture containing a polymeric compound consisting of an ion exchange resin, an acrylamide mixture containing at least one bisacrylamide and at least one acrylamide, and a...
8506783 Three-dimensional nanochannel device and method of manufacturing the same  
A three-dimensional nanochannel device and a method of manufacturing the same are provided. In the device, a first substrate, a second substrate, and a channel layer sandwiched by the first and...
8506785 Analysis apparatus with renewable electrode contact tip  
An analysis apparatus enables a plurality of analysis processes to be accurately and efficiently performed. The analysis apparatus includes a detention tank in which a specimen is stored, and a...
8481125 Mitigation of biomolecular adsorption with hydrophilic polymer additives  
Molecular adsorption to the microfluidic device surfaces can be passively and actively mitigated by mixing certain hydrophilic polymers (organic polymers with repeating hydrophilic groups—the...
8480970 Analytical pretreatment device  
The present invention relates to an analytical pretreatment device, comprising a supporting material 1, m inlet ports 3 as fluid injection ports, n outlet ports 4 as fluid outlet port, m×n hollow...
8480971 Analytical pretreatment device  
The present invention relates to an analytical pretreatment device, comprising a supporting material 1, m inlet ports 3 as fluid injection ports, n outlet ports 4 as fluid outlet port, m×n hollow...
8470149 Electrowetting dispensing devices and related methods  
A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality...
8465637 Ion sensor for fluid and method for its manufacture  
The invention provides a method for the measurement of a concentration of a charged species in a sample, the sample having a plurality of types of charged species and at least one insoluble...
8460530 Method for modifying the concentration of reactants in a microfluidic device  
A method of modifying the concentration of reactants and carrying out a chemical reaction on a microfluidic device in which first and second reactants are delivered into a reaction channel...
8454811 Microfluidic system  
A method for forming a microfluidic channel with improved flow characteristics for one or more analytes is disclosed. A microfluidic channel having modified surfaces is formed in fused silica. The...
8454812 Capillary electrophoresis apparatus  
A capillary electrophoresis apparatus capable of efficiently using a polymer in a polymer container is provided. The present invention relates to a mechanism for efficiently using the polymer in...