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8449746 Systems and methods for coupling molecule separation devices to analytical instruments  
Described is a capillary that interfaces with an analysis system. The capillary comprises a non-conductive tubing and a conductive region proximate to an output end of the non-conductive tubing....
8448790 Surface charge enabled nanoporous semi-permeable membrane for desalination  
A filter includes a membrane having a plurality of nanochannels formed therein. A first surface charge material is deposited on an end portion of the nanochannels. The first surface charge...
8414755 Microfluidic separation device  
A microfluidic separation device is provided that includes a sample channel having a first sample channel region and a second sample channel region, where a cross-section of the first sample...
8366896 Capillary electrophoresis device  
Provided is a capillary electrophoresis device including a holder preventing a septum from coming off when a capillary is pulled out, and also allowing containers to be taken out in any order. In...
8366897 Gradient elution electrophoresis and detectorless electrophoresis apparatus  
A microfluidic apparatus and method for performing electrophoretic separation of compounds. The method comprises the steps of: a) providing a separation buffer; b) providing a sample solution in...
8361292 Method for analyzing hemoglobin by capillary electrophoresis and additive used therein  
The present invention provides a method for analyzing hemoglobin by capillary electrophoresis, that allows the apparatus to be smaller in size, allows a highly precise analysis to be obtained, and...
8357281 Multi-wavelength fluorescence detection system for multiplexed capillary electrophoresis  
Using multiple dichroics mirrors to split and redirect different wavelength regions of light in a multi-wavelength fluorescence detection system.
8354077 Universal interface for a micro-fluidic chip  
An integrated capillary electrophoresis system comprising a universal interface is disclosed. The universal interface includes one or more of the following structural elements: a chip assembly...
8349159 Microfluidic device for detection of charged analytes contained in an electrolyte and a method for detecting charged analytes contained in an electrolyte  
A device for selective preconcentration/detection of charged analytes contained in an electrolyte having at least two reservoirs separated by at least one rectilinear microchannel with no...
8350243 Optically induced dielectrophoresis chip for control and analysis of bio-molecules  
An optically-induced dielectrophoresis chip including a substrate, a first electrode layer disposed on the substrate, and an interface modification layer disposed on the first electrode layer. A...
8337685 Serum components that bind to threat agents  
Low molecular weight serum components (less than 10,000 m.w.), in vaccinated animals and a human subject who has been exposed to a threat agent inadvertently, bound to purified O-polysaccharide...
8329115 Nanofluidic preconcentration device in an open environment  
This invention provides a device and methods for increasing the concentration of a charged species in solution, wherein the solution containing the concentrated species is exposed to the...
8317991 Process for electrokinetic migration through liquid membranes  
Device and Process for isolating, purifying, concentrating and/or enriching at least one organic compound by electrokinetic migration through liquid membranes by use of an electronic potential and...
8313698 Droplet-based nucleic acid amplification apparatus and system  
The present invention relates to a droplet-based nucleic acid amplification apparatus and system. According to one embodiment, a droplet microactuator is provided made using a first substrate...
8307994 Surface charge enabled nanoporous semi-permeable membrane for desalination  
A filter includes a membrane having a plurality of nanochannels formed therein. A first surface charge material is deposited on an end portion of the nanochannels. The first surface charge...
8298392 Microfluidic devices and methods of using same  
The presently-disclosed subject matter provides microfluidic devices comprised of two or more carbon nanotube membranes disposed at predetermined intervals within a microchannel. Further provided...
8293083 Nanopore electrode, nanopore membrane, methods of preparation and surface modification, and use thereof  
Provided are fabrication, characterization and application of a nanodisk electrode, a nanopore electrode and a nanopore membrane. These three nanostructures share common fabrication steps. In one...
8282799 Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields  
The present invention relates to methods and devices for separating particles according to size. More specifically, the present invention relates to a microfluidic method and device for the...
8283157 System and method for increasing polymer/nanopore interactions  
An electrolytic system includes an analyte chamber having an access port for introducing a sample containing a molecules of interest, such as DNA. Electrodes create an electric field along a...
8277761 Channelless fluidic sample transport medium  
A fluidic device (100) comprising a substrate (101) and a transport medium (103) provided on the substrate (101) to define a transport path for transporting a fluidic sample (104) driven by an...
8263671 Ion exchangeable mixture and method of producing the same  
An ion exchangeable mixture containing a polymeric compound consisting of an ion exchange resin, an acrylamide mixture containing at least one bisacrylamide and at least one acrylamide, and a...
8257569 Capillary array unit and capillary electrophoresis apparatus  
In a capillary electrophoresis apparatus, a capillary array unit has a capillary array including capillaries having a capillary head and a detection unit, a frame for supporting the capillary...
8257570 Electrophoresis chip and electrophoresis unit having the same  
In order to provide a high-performance electrophoresis chip and an electrophoresis unit having the same that can restrain the diffusion of sample at an intersection between the electrophoresis...
8252162 Capillary electrophoresis apparatus  
The invention provides a capillary electrophoresis apparatus which can improve the operability and measuring speed. According to the invention, a sensor for identifying the type of sample...
8251672 Electrokinetic pump with fixed stroke volume  
An electrokinetic pump and fluid delivery system is provided that may include any of a number of features. One feature of the fluid delivery system is that it can deliver a fixed volume of fluid...
8246805 Micro-fluidic chip and flow sending method in micro-fluidic chip  
Disclosed herein is a micro-fluidic chip including a hollow area into which a charged droplet is introduced, and an electrode configured to be provided toward the hollow area. Movement direction...
8237117 Methods and interfaces for single and multidimensional separations for characterization and/or identification of molecules by mass spectrometry  
The present invention relates a use of the electrocapture-based separation technology combined with mass spectrometrical fragmentation methods, e.g. sequence of polypeptides by collision-induce...
8232074 Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells  
The present invention relates to methods of measuring electrical properties of a cell using electrode devices comprising tapered nanotips having submicrometer dimensions (“nanoelectrodes”) for...
8221604 Method for controlling substance transfer  
Transfer of fluid substances, and/or substances comprised in fluid substances, is controlled by introducing a separation medium, which prevents transfer of the fluid substances, and/or the...
8221606 Electrophoresis chip and electrophoresis unit having the same  
In order to provide a high-performance electrophoresis chip and an electrophoresis unit having the same that can restrain the diffusion of sample at an intersection between the electrophoresis...
8187442 Microchip processing method and apparatus  
The processing apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips...
8182746 Electrophoresis process using a valve system  
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus...
8142635 Capillary array  
A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis,...
8142630 Electrophoresis devices and methods for focusing charged analytes  
Devices are provided for separating and focusing charged analytes, comprising a separation chamber and two or more electrodes, for example, an electrode array. A membrane separates the separation...
8129624 Pressure sensor  
A pressure sensor includes a sense element port, a support ring and a plurality of interference fit slits to provide a flexible interference fit between the sense element port and the support ring...
8105471 Nanofluidics for bioseparation and analysis  
The invention includes nanochannel devices and methods for using such nanochannel devices for separating molecules, ions and biomolecules. The nanochannel devices have at least one nanochannel...
8101037 Phase-changing sacrificial materials for manufacture of high-performance polymeric capillary microchips  
A microchip with capillaries and method for making same is described. A sacrificial material fills microchannels formed in a polymeric substrate, the filled microchannels are covered by a top...
RE43122 Apparatus and method for trapping bead based reagents within microfluidic analysis systems  
The present invention provides an on-chip packed reactor bed design that allows for an effective exchange of packing materials such as beads at a miniaturized level. The present invention extends...
8097470 Microchip analysis method and apparatus  
The analysis apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips...
8083821 System for modifying the atmosphere within an enclosed space and incubator system including the same  
System for modifying the chemical composition of atmosphere within an enclosed space and incubator system including such a system. The concentration of oxygen within the enclosed space may be...
8083915 Methods for forming small-volume electrical contacts and material manipulations with fluid microchannels  
A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging...
8083917 Methods and apparatus for the location and concentration of polar analytes using an alternating electric field  
A method is disclosed for effecting the concentration of a polar analyte in an alternating electric field. In the method, a relative translation of the polar analyte and an alternating electric...
8057191 Electrokinetic micropump having ion-exchange membranes  
The invention is directed to the elimination of changes of the chemical composition of a pumped liquid caused by introduction of strange components or by modification of original components....
8052856 Support for capillaries, case for constraining capillaries including the same  
A support for capillaries comprises a ceramic member having a flat surface area on which the capillaries are to be aligned. The flat surface area has a flatness of not more than 0.02 mm and has a...
8038862 Connecting structure of a liquid sending apparatus, fuel-cell type electricity generating apparatus, and electronic device  
Disclosed is a connecting structure of a liquid sending apparatus, including: an electroosmotic flow pump having first and second electrodes upstream and downstream of an electroosmosis material;...
8037902 Fluid logic device  
Novel fluid logic devices are disclosed. Certain examples of the fluid logic devices include two or more fluid logic gates that are each operative to select and/or direct analytes in a sample into...
8030092 Controlled electrophoresis method  
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus...
8021531 Method for modifying the concentration of reactants in a microfluidic device  
A method of carrying out a chemical reaction on a microfluidic device in which a first reactant at a first concentration is delivered into a reaction channel; within the reaction channel the...
8012327 Capillary electrophoresis apparatus and electrophoresis method  
An object of the present invention is to provide a capillary electrophoresis apparatus in which simultaneity can be ensured between sensitivity and data acquisition to decrease a pull-up signal...
8012430 Methods for producing microchannel chips, microchannel chips, methods for separating biomolecules using the microchannel chips, and electrophoretic apparatus having the microchannel chips  
The methods for producing microchannel chips of the present invention comprise the steps of shielding substrate surfaces on which groove-like channels have been formed, using a mask that exposes...