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7385210 Device for spectroscopy using charged analytes  
A device for spectroscopy using charged analytes has an electron generator, which sends electrons through membrane into a charging chamber. The thermal strain of the membrane may be lowered...
7344628 Capillary electrophoresis-electrochemical detection microchip device and supporting circuits  
The present invention is a capillary electrophoresis device, comprising a substrate; a first channel in the substrate, and having a buffer arm and a detection arm; a second channel in the substrate...
7338808 Method and apparatus for determining zeta potential using alternating current electric field and T channel  
Provided is a method for determining a zeta potential generated between a solid wall and a solution. The method includes (a) injecting an electrolyte solution into a first inlet of a T channel,...
7332902 Micro sensor for electrochemically monitoring residue in micro channels  
The present invention provides a micro sensor for monitoring the cleaning and drying processes for very high aspect ratio micro channels in dielectric films oriented parallel to the fluid-solid...
7329333 Uniform laser excitation and detection in capillary array electrophoresis system and method  
A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is...
7315021 Charged droplet spray probe  
An improved sample introduction probe is disclosed for the production of ions from liquid sample solutions in an electrospray ion source. Nebulization of a liquid sample emerging from the end of an...
7307141 Thermoresponsive sensor comprising a polymer solution  
Methods and apparatus for measuring and/or controlling the temperature on the surface or inside of micro chips are provided, including using thermally responsive polymers.
7282126 System and method for determining known DNA variants with temperature gradient electrophoresis  
The present invention relates to a method of determining the genotype of a sample polynucleotide having at least a first variant site. At least a portion of the sample polynucleotide is amplified...
7264702 Total analyte quantitation  
Methods for determining total analyte concentrations and amounts, especially in combination with analyte separations are provided. Microfluidic devices are used to separate analyte mixtures and...
7258775 Method and device for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body  
The invention relates to a method for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body. The proteins...
7250099 Optical detection alignment coupling apparatus  
An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical blocks...
7250098 Multi-capillary array electrophoresis device  
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than...
7244961 Integrated system with modular microfluidic components  
Modular fluidic microchips, systems integrating such microchips, and associated preparative and analytical methods are presented.
7217350 Mobility and effects arising from surface charge  
A method of, and apparatus for, automatically determining an electric charge—related characteristic or derived parameter of particles in a dispersion or of a cell wall, comprises having a...
7214299 Method for separation, identification and evaluation of microbes and cells  
The method entails using capillary electrophoresis or capillary isoelectric focusing to separate intact microbes. The capillary system can be a conventional capillary tube or a microfluidic device....
7195699 Electrophoresis member, production thereof and capillary electrophoresis apparatus  
An electrophoresis member is produced by laying a plurality of capillaries on an adhesive layer born on a support layer to form a capillary layer, laminating thereon a second support layer, and...
7125478 Microscale electrophoresis devices for biomolecule separation and detection  
The present invention relates to microfabrication and utilization of microscale electrophoresis devices as well as the separation and detection of biomolecules in microscale electrophoresis...
7118662 Electrophoresis apparatus  
The windows 5 a, 5 b are configured so that the thickness of the upper and lower parts of the substrate formed therein with the channels becomes thinner in these parts than in other parts. An...
7118660 Method and apparatus for analyzing a mixture of sample substances  
An apparatus for analyzing a mixture of sample substances comprises a fluid-guiding structure wherein the sample substances are moving essentially in one dimension along the structure and are...
7112266 Multi channel capillary electrophoresis device and method  
Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein...
7108775 Apparatus and method for confining eluted samples in electrophoresis systems  
The present teachings provide a microfluidic apparatus comprising a body defining at least one channel that extends through said body, the channel including an inlet and an outlet; and an electrode...
7090758 Capillary array electrophoresis scanner  
An improved rotary confocal fluorescence scanner capable of detecting analytes separated on over a 1,000 capillaries simultaneously. This system uses a confocal microscope objective and mirror...
7060171 Methods and systems for reducing background signal in assays  
Methods and systems of monitoring reactions, e.g., assays, that filter out background signal from substrate, in detecting the product. The methods and systems controllably move detectable reaction...
7037417 Mechanical control of fluids in micro-analytical devices  
An apparatus for manipulating fluid samples comprises a micro-chip device having first and second covered channels, each channel having openings at both ends. The channels intersect to form a...
7033475 Electrophoretic apparatus  
An electrophoretic apparatus which can analyze multiple tests specimens and being comprised of an electrophoretic member having a relatively simple configuration of passages, such that one or a...
7029562 Capillary array electrophoresis apparatus  
The electrophoresis apparatus has plural capillaries for separating fluorephore-labeled samples by electrophoresis, fluorescence detecting parts provided in a part of these capillaries arranged in...
7015466 Electrosonic spray ionization method and device for the atmospheric ionization of molecules  
There is described a device and method for generating gaseous ions of a sample material such as molecules in solution at atmospheric pressure. The device includes a conduit for receiving a solution...
7010391 Methods and systems for control of microfluidic devices  
The present invention provides control methods, control systems, and control software for microfluidic devices that operate by moving discrete micro-droplets through a sequence of determined...
7002144 Transfer line for measurement systems  
An enhanced transfer system that increases the accuracy and sensitivity of a measurement system is disclosed. In one embodiment, the transfer system includes transfer tubing that transports samples...
6998251 Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics  
Reactors and methods for miniaturized reactions having enhanced reaction kinetics. In particular the subject matter is directed to chemical and biological reactions conducted in a nanoporous...
6991712 Spectral calibration of fluorescent polynucleotide separation apparatus  
The invention relates to methods, compositions, and systems for calibrating a fluorescent polynucleotide separation apparatus. One aspect of the invention is multiple color calibration standards...
6989085 Method for separation of compounds using cycling denaturing conditions  
A method for electrophoretic separation in separation channels in which the temperature of the channel is repeatedly cycled during the course of the separation.
6984525 Method for automated isolation of fractions in multichannel separation systems  
A method to collect a plurality of target zones from a plurality of channels. The method includes introducing a plurality of compound mixtures into a plurality of microchannels on a microfabricated...
6982029 Electrophoretic method and system having internal lane standards for color calibration  
An electrophoretic system having a plurality of separation lanes is provided with an automatic color calibration feature in which each lane is separately calibrated. For each lane, a dye matrix...
6974527 Multidimensional separations employing an array of electrophoresis channels  
The present invention relates to a method for separating components of a sample. The method includes obtaining a first separation of the sample components along a first dimension wherein the sample...
6969452 Two-dimensional protein separations using chromatofocusing and multiplexed capillary gel electrophoresis  
Disclosed is a two-dimensional protein separation method. It makes separating a protein sample by chromatofocusing into a plurality of aliquots, and then loading each aliquot into a separate...
6964736 Method and apparatus for analysis and sorting of polynucleotides based on size  
The invention relates to a microfabricated device and methods of using the device for analyzing and sorting polynucleotide molecules by size.
6964735 Method for moving charged particles  
Devices and methods are disclosed for moving charged molecules through a medium by the application of a plurality of electrical fields of sufficient strength and applied for sufficient amounts of...
6953520 Capillary electrophoresis probes and method  
A novel class of capillary electrophoresis probes and a method of employing the same are described. The novel class of capillary electrophoresis probes are comprised of one or more vinylogous...
6942773 Particle sizer and DNA sequencer  
An electrophoretic device separates and detects particles such as DNA fragments, proteins, and the like. The device has a capillary which is coated with a coating with a low refractive index such...
6932940 Optical detection in bio-separation device using axial radiation input  
In a bio-separation system, incident radiation (e.g., from a laser or LED source) for detection of separated analytes is directed at the detection zone axially along the separation medium, instead...
6929779 Optical detection in bio-separation device using axial radiation output  
In a bio-separation system, emitted radiation signals representative of sample analytes are collected from the detection zone axially along the separation medium, instead of through the boundary...
6925612 Device and method for selecting electrophoresis band  
The present invention aims at easy and efficient selection of bands present on a lane. A region 502 is set on a display of a lane 503 having a plurality of bands 504 to 508, based on an...
6908594 Efficient microfluidic sealing  
Improved sealing for microstructures in microfluidic devices having a plurality of units is provided by providing collars surrounding the openings to the microstructures, such as reservoirs. The...
6906797 Side light activated microfluid channels  
Devices are provided comprising reflecting channels for directing horizontally a vertical light beam through a multiplicity of streams. The devices provide particular applications in microfluidics,...
6905586 DNA and RNA sequencing by nanoscale reading through programmable electrophoresis and nanoelectrode-gated tunneling and dielectric detection  
An apparatus and method for performing nucleic acid (DNA and/or RNA) sequencing on a single molecule. The genetic sequence information is obtained by probing through a DNA or RNA molecule base by...
6887359 Chemical micro-sensor  
An integrated optical capillary electrophoresis system for analyzing an analyte. A modulated optical pump beam impinges on an capillary containing the analyte/buffer solution which is separated by...
6886576 Method of controlling the flow in a flow system  
A method and flow system for controlling the flow of a liquid in a flow system, the liquid flow comprising particles and being led into a channel thereof. The method comprises the steps of...
6878255 Microfluidic devices with thick-film electrochemical detection  
An apparatus for conducting a microfluidic process and analysis, including at least one elongated microfluidic channel, fluidic transport means for transport of fluids through the microfluidic...
6864055 Method for detecting nucleic acids  
A method of detecting nucleic acid fragments in plural samples is performed by the steps of: attaching an electroconductive label to nucleic acid fragments in one sample and attaching a different...
Matches 1 - 50 out of 287 1 2 3 4 5 6 >