Matches 101 - 150 out of 255 < 1 2 3 4 5 6 >
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6296749 System and method for chromatography and electrophoresis using circular optical scanning  
A system and method is disclosed for chromatography and electrophoresis using circular optical scanning. One or more rectangular microchannel plates or radial microchannel plates has a set of...
6290839 Systems for electrophoretic transport and detection of analytes  
The invention relates to compositions and methods useful in the electrophoretic transport of target analytes to a detection electrode comprising a self-assembled monolayer (SAM). Detection proceeds...
6291439 Methods for diagnosing atherosclerosis by measuring endogenous heparin and methods for treating atherosclerosis using heparin  
The present invention provides methods for measuring endogenous heparin in a mammal at levels that were previously undetectable. The present invention further features methods for assessing the...
6258238 Method of producing a capillary, a capillary for an electrophoresis device and an electrophoresis device including such a capillary  
A method for producing a capillary comprises the steps of providing first a capillary having a uniform inner width throughout its length, introducing then an etchant into the capillary, and...
6221226 Methods and systems for monitoring and controlling fluid flow rates in microfluidic systems  
The present invention generally provides methods and systems for monitoring and controlling electroosmotic flow rates in microfluidic systems. Generally, such methods and systems monitor flow rates...
6156576 Fast controllable laser lysis of cells for analysis  
Fast lysis of a single cell or cellular component thereof is performed by generating a shock wave in a medium in which the cell or cellular component thereof is positioned. The cell or cellular...
6140048 System for distinguishing fluorescent molecule groups by time resolved fluorescence measurement  
System and method for distinguishing at least two types of molecule groups that are bound to analyte molecules and which have different fluorescent characteristics. The system performs...
6132579 Liquid separation  
A liquid is separated into its constituent species by electrophoresis along a capillary channel. A plurality of the channels is provided in the thickness of an injection molded plastics disc. The...
6132578 Method and apparatus for electrophoresis separation and detection  
An electrophoresis separation and detection apparatus for separating and detecting fluorophore-labeled samples by electrophoresis, which comprises a migrating and separating means for...
6126804 Integrated polymerase chain reaction/electrophoresis instrument  
A new approach and instrument for field identification of micro-organisms and DNA fragments using a small and disposable device containing integrated polymerase chain reaction (PCR) enzymatic...
6123819 Nanoelectrode arrays  
An array of electrodes at the atomic or nano scale (nanoelectrodes) is built on a chip. The spatial distribution, height, width and electrochemical composition of the nanoelectrodes is varied, such...
6120666 Microfabricated device and method for multiplexed electrokinetic focusing of fluid streams and a transport cytometry method using same  
A microfabricated device and method for electrokinetic transport of a liquid phase biological or chemical material is described. In accordance with one aspect of the present invention there is...
6103537 Capillary assays involving separation of free and bound species  
The present invention concerns methods for masking inhomogeneity of a member of a specific binding pair (sbp) employed in a capillary electroseparation. The method comprises binding the sbp member...
6103083 Capillary electrophoresis apparatus and method  
The present invention relates to an electrophoresis apparatus having a plurality of capillaries arranged in a plane such that a curving contour is formed by the intersection points of each of the...
6086737 Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes and suitable labels therefor  
To sequence DNA automatically, DNA marked with far infrared, near infrared, or infrared fluorescent dyes are electrophoresed in a plurality of channels through a gel electrophoresis slab or...
6068749 Subatmospheric, variable pressure sample delivery chamber for electrospray ionization/mass spectrometry and other applications  
A subatmospheric, variable pressure sample delivery chamber, useful as an electrospray ionization device for introducing a sample into a mass spectrometer or as a sample delivery device for...
6056859 Method and apparatus for staining immobilized nucleic acids  
A method for staining immobilized nucleic acids includes the steps of affixing DNA probes to a solid substrate, moving target DNA material into proximity with the DNA probes, whereby the target DNA...
6048444 Capillary electrophoresis apparatus  
A capillary electrophoresis apparatus of the invention has: a plurality of capillaries which are filled with a migration medium and have first ends into which samples are injected and second ends...
6042708 Microchip electrophoretic method and apparatus  
In order to irradiate a constant range of a separation passage of a microchip, light from a light source linearly extending along the separation passage is transmitted through a cylindrical lens...
6027627 Automated parallel capillary electrophoretic system  
An automated electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends projecting from...
6027624 Automated capillary electrophoresis method and apparatus  
The automated capillary electrophoresis method and apparatus analyzes a sample in real time or near real time in order to identify the presence of a number of different ions as well as other sample...
6001230 Automated capillary electrophoresis apparatus  
An integrated apparatus for capillary electrophoresis which is automated using conveyors which carry vials containing electrolytes and samples, a capillary contained in a modular, portable, and...
5985120 Rapid analysis of analyte solutions  
The separation profile results of capillary zone electrophoresis can be analyzed very rapidly, e.g., in 45 seconds or less, if the results are analyzed using a successive subtracting procedure to...
5964998 DNA detector and DNA detection method  
An electrophoresis apparatus for detecting samples migrating in migration portions includes a plurality of gel separation portions separate from one another and having respective ends disposed...
5954931 Electrophoresis apparatus and method involving parallel channels  
An electrophoresis apparatus includes a substrate (34) which supports a filling region (22) and a plurality of electrophoresis lanes (20). The filling region (22) communicates a sample to the...
5932080 Mobility-based and normalized capillary electrophoresis  
Identification and quantification of constituents of a sample is achieved by mobility-based electropherograms obtained from capillary electrophoresis, the mobilities being normalized by zero...
5922184 Computer-directed detection of paraproteins  
Identification and quantification of paraproteins in a sample is achieved by Fourier analysis of mobility-based electropherograms obtained from capillary electrophoresis. The use of a computer...
5917606 Photometric flow apparatus for small sample volumes and method of making same  
A photometric apparatus (100) for small sample volumes comprises a cell body (102), a light input means (104) arranged adjacent to a first surface of the cell body (102), a light source (105)...
5916428 Automated system for multi-capillary electrophoresis having a two-dimensional array of capillary ends  
An automated electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends projecting from...
5900934 Capillary chromatography detector apparatus  
An apparatus to effect multiple simultaneous separations to measure absorbance, comprising a photodetector array comprising a plurality of photosensitive elements connected to provide a serial...
5900132 Capillary holder  
A holder (10) is provided for securing a capillary (30) having a window section (28) including first and second edges (46) (48) to a mount (80). The holder (10) comprises a retaining surface (14)...
5891314 Method and apparatus for correcting lens non-uniformities in an electrophoresis apparatus  
A method and apparatus for correcting non-uniformities in the lens assembly of an electrophoresis apparatus is provided. Assuming a detector with a uniform responsivity as well as a uniform...
5888363 Apparatus and method for interfacing an open capillary and detector for conducting off-column analyses  
An apparatus and method for interfacing a capillary with a detector is disclosed. In particular, a capillary that is used in a capillary electrophoresis technique is interfaced with an off-column...
5888366 Capillary made of polymer material having a modified inside surface and process for its production  
A capillary made of plastics material that is suited for use in capillary electrophoresis. The capillary has its inner surface chemically modified for the generation of properties different from...
5879528 Means and method of detection in chemical separation procedures  
A means and method for indirect detection of constituent components of a mixture separated in a chemical separation process. Fluorescing ions are distributed across the area in which separation of...
5872010 Microscale fluid handling system  
A microscale fluid handling system that permits the efficient transfer of nanoliter to picoliter quantities of a fluid sample from the spatially concentrated environment of a microfabricated chip...
5863401 Simultaneous analysis of analytes by immunoassay using capillary electophoresis with laser induced fluorescence  
Homogeneous competitive immunoassay methods for simultaneously detecting analytes using capillary electrophoresis and fluorescent detection systems are described. The methods are useful for...
5861124 Method and apparatus for detecting denaturation of nucleic acid  
An apparatus for detecting denaturation of a nucleic acid, including: denaturation condition controlling means for controlling condition of denaturation under which a double-stranded nucleic acid...
5858644 Analysis of analytes in biological fluids  
A method for detecting an analyte in a sample uses both the specificity of an enzymatic reaction and the separation power of capillary electrophoresis. In general, the method comprises: (1)...
5858187 Apparatus and method for performing electrodynamic focusing on a microchip  
A microchip device includes a focusing channel, in which an electric field strength established in the focusing channel is controlled relative to an electric field strength established in a...
5856082 Devices and methods for characterizing proteins and peptides  
The present invention provides analytical devices for the characterization of the primary structure of proteins and peptides, comprising a microenzyme reactor, a separation device, an interface...
5856671 Capillary electrophoresis-mass spectrometry interface  
An interface for connecting an electrophoresis capillary to a mass spectrometer sprayer tube includes a first length of support tubing having an axial bore receiving and aligning the capillary and...
5853668 Apparatus allowing sequential chemical reactions  
A first reactant is immobilized i.e. in a porous matrix (50), adjacent a sample electrode (46) within a reaction chamber. Energizing of the electrode (46) electrophoretically attracts a mobile...
5833826 Method and apparatus for reducing the distortion of a sample zone eluting from a capillary electrophoresis capillary  
An electrophoresis system including means for reducing the distortion of a sample zone eluting from a capillary electrophoresis separation capillary is disclosed. The system includes one or more...
5835231 Broad band intra-cavity total reflection chemical sensor  
A broadband, ultrahigh-sensitivity chemical sensor is provided that allows etection through utilization of a small, extremely low-loss, monolithic optical cavity. The cavity is fabricated from...
5815258 Liquid sample cell for an optical measurement apparatus  
A liquid sample cell used in an optical measurement apparatus in which a liquid sample flows through a flow path of the sample cell while a measurement light travels through the liquid sample in...
5810985 Electrophoretically mediated chemical analysis  
Disclosed are methods of electrochemical analysis of an analyte in a sample. The methods include providing a sample comprising an analyte, and introducing the sample into a capillary tube...
5799773 Method and apparatus for correcting lens and detector non-uniformities  
A method and apparatus for correcting an image of an electrophoresis gel for lens and detector non-uniformities is provided. The removal of such non-uniformities, in conjunction with a uniform...
5798032 Method and apparatus for automated carbohydrate mapping and sequencing  
Methods and apparatus are disclosed for improved mapping and sequencing of carbohydrate polymers. In one aspect, the improvement includes a means for coupling two capillary electrophoresis (CE)...
5792330 Lanthanide metal cations for concurrent detection and separation in capillary electrophoresis  
The present invention provides a method for direct detection concurrently with separation in capillary electrophoresis using a lanthanide cation selected from the group consisting of Tb(III),...
Matches 101 - 150 out of 255 < 1 2 3 4 5 6 >