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7597790 |
Flow control systems
A flow controller which uses a combination of hydrostatic pressure and electroosmotic flow to control the flow of a fluid. A driving fluid ( 1204 ) whose flow rate is dependent on both hydrostatic...
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7588671 |
Microfluidic treatment method and device
The present invention relates to a microchip apparatus using liquids. More specifically, the invention provides a liquid mixing apparatus comprising at least two microchannels for introducing...
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7586091 |
Mass spectrometric system and mass spectrometry
After a sample is previously separated into plural components in a channel formed in a microchip ( 353 ), the channel is irradiated along a separation direction with a laser beam from a laser...
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7578916 |
Emulsions of ionic liquids
The present teachings provide emulsions using ionic liquids for separation of biomolecules and related methods, compositions, and devices.
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7578915 |
Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis
A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or...
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7572357 |
Chiral temperature gradient focusing
A method and device are provided for concentrating and separating materials in fluids within a fluidic device having a fluid conduit such as a channel or capillary. The concentration is achieved by...
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7556932 |
Particle based homogeneous assays using capillary electrophoresis with laser-induced fluorescence detection
The invention provides highly sensitive and rapid homogeneous assays which employ particle-enhanced assay formats in concert with capillary electrophoresis and laser-induced fluorescence (LIF)...
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7553622 |
Process for preparing processed sample liquid solution for electrophoresis
A process for preparing a processed sample liquid solution for gel electrophoresis, comprising (a) treating a sample comprising a cell suspension in a non-shearing manner to produce a processed...
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7537679 |
Materials classifier, method of using, and method of making
The present invention relates to a method of classifying charged molecules such as proteins for quantitative analysis. An analyte solution of the molecules is subjected to separational forces may...
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7534334 |
Apparatus and method for concentrating and filtering particles suspended in a fluid
Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid...
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7527767 |
Micro-fluidic system with sensors respectively assigned to plural fluid paths
To monitor functions in a micro-fluidic system having mutually similar parallel fluid paths, sensors ( 7 ) are assigned to the individual fluid paths ( 5 ) at the same respective locations, in...
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7517441 |
Electrophoretic buffer
By using an electrophoretic buffer comprising a polymerized polymer micelle formed by the steps comprising dispersing into an aqueous medium a block copolymer represented by HPLS-HPBS-PLZA, wherein...
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7491305 |
High density electrophoresis device and method
The present invention provides, in one aspect, an apparatus or electrophoretic separation of analytes. In one aspect, the apparatus comprises a disc-shaped substrate defining (1) a central...
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7465381 |
Electrokinetic molecular separation in nanoscale fluidic channels
A method for separation of mixtures in fluidic systems through electrokinetic transport by use of nanochannels when the fluidic systems approach the size of an electrical double layer, thereby...
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7459069 |
Electrophoresis device and the use thereof
The invention relates to a device for electrophoretically separating molecules. The inventive device comprises: at least one plate having a top side and an underside; a first separating channel...
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7459068 |
Multi-capillary electrophoresis apparatus
A multi-capillary electrophoresis apparatus is provided for reducing errors during analysis caused by fluctuations in electrophoresis time among plural capillaries of the apparatus. The...
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7455758 |
Fluidic microsystem comprising field-forming passivation layers provided on microelectrodes
Described is a fluidic microsystem ( 100 ) including at least one channel ( 10 ) through which a particle suspension can flow; and first and second electrode devices ( 40, 60 ) which are arranged...
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7439075 |
Method and device for withdrawing suspended microparticles from a fluidic microsystem
A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem ( 10 ) is described, whereby the fluid flow converges with at least one output flow to form a discharge...
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7425254 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Fractionation of macro-molecules using asymmetric pulsed field electrophoresis
A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field...
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7422669 |
Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream
A microfluidic device and method for forming and dispensing minute volume segments of a material are described. In accordance with the present invention, a microfluidic device and method are...
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7413642 |
Material separation device
A separating device for use in separating electrically charged components, e.g., by electrophoresis, comprises a channel branched at a branch point to provide a main feed channel ( 105 ) connected...
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7410559 |
Electrophoresis methods
A separation carrier comprising β-1,3-glucan and/or methyl cellulose; a running buffer comprising the separation carrier; a method of capillary electrophoresis or microchip electrophoresis,...
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7396444 |
Device to operate a laboratory microchip
In a device to operate and handle a laboratory microchip to chemically process or analyze substances, the microchip is on a chip holder ( 41 ) that is part of a first assembly ( 42 ). The first...
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7384525 |
Electrophoretic analysis system having in-situ calibration
An electrophoretic system having a plurality of separation lanes is provided with an automatic calibration feature in which each lane is separately calibrated. For each lane, the calibration...
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7347921 |
Apparatus and method for threading a biopolymer through a nanopore
The present invention provides an apparatus and method for threading a biopolymer through a nanopore. The apparatus of the present invention provides a substrate having a channel with a channel...
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7344628 |
Capillary electrophoresis-electrochemical detection microchip device and supporting circuits
The present invention is a capillary electrophoresis device, comprising a substrate; a first channel in the substrate, and having a buffer arm and a detection arm; a second channel in the substrate...
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7341653 |
Method and device for separating particle
A plurality of types of liquid with different electrical conductivity flow through a micro channel having a plurality of channels. When an electric field is applied thereto, an electrokinetic...
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7341652 |
Stationary capillary electrophoresis system
A system and method for capillary electrophoresis are provided for analyzing a macromolecule prepared from a complex liquid mixture. In particular applications, methods and apparatus are provided...
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7332902 |
Micro sensor for electrochemically monitoring residue in micro channels
The present invention provides a micro sensor for monitoring the cleaning and drying processes for very high aspect ratio micro channels in dielectric films oriented parallel to the fluid-solid...
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7316770 |
Method of electrophoresis, electrophoresis apparatus and capillary array
A method of electrophoresis, an electrophoresis apparatus and a capillary array in which a fluorescently labelled sample is supplied into capillaries in a capillary array constituted by a plurality...
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7314550 |
Analytical separations with polyelectrolyte layers, molecular micelles, or zwitterionic polymers
Polymeric surfactants (molecular micelles) are disclosed for use in open tubular capillary electrochromatography or in high performance liquid chromatography. For example, fused silica capillaries...
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7307141 |
Thermoresponsive sensor comprising a polymer solution
Methods and apparatus for measuring and/or controlling the temperature on the surface or inside of micro chips are provided, including using thermally responsive polymers.
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7297244 |
Capillary electrophoresis systems and additives
Capillary electrophoresis systems, reagents, and processes for analyzing a sample which includes at least one protein constituent are disclosed. The processes involve introducing the sample into a...
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7297243 |
Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels
A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging membrane...
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7294247 |
Electrophoretic separating device and method for using the device
The invention concerns to an electrophoretic separation device comprising a separation channel having at least one in- and outlet opening at the beginning and at the end of the channel and one...
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7285421 |
Apparatus for capillary electrophoresis and associated method
An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises...
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7279082 |
Method of reacting carboxylic acids
A carboxylic acid molecule (R COOH) is subjected to an electric field in a micro-reactor. The molecule decarboxyles to form a radical (R • ). Two radicals (R • ) can dimerise to form the...
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7265348 |
Apparatus for dispensing a sample in electrospray mass spectrometers
The present invention relates to an apparatus to dispense a sample for subsequent electrospray ionisation (ESI) mass spectrometry (MS) analysis, to a method of fabricating such apparatus and to...
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7252928 |
Methods for prevention of surface adsorption of biological materials to capillary walls in microchannels
Methods for reducing surface adsorption of biological materials to the walls of microfluidic conduits in microscale devices are provided. In an example of the methods, one or more colloidal-size...
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7250096 |
Capillary electrophoresis apparatus and method
An electrophoresis apparatus is provided in which negative effects caused by abnormalities in a current-carrying path in an electrophoresis apparatus can be avoided or reduced. The current flowing...
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7244961 |
Integrated system with modular microfluidic components
Modular fluidic microchips, systems integrating such microchips, and associated preparative and analytical methods are presented.
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7243670 |
Microfluidic system
A microfluidic system, particularly a microfluidic chip, with at least one operational channel, in which a fluid and/or the constituents contained therein are moveable in the direction of the...
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7238269 |
Sample processing device with unvented channel
A device includes a substrate having first and second major surfaces and a hub that defines an axis of rotation for the substrate, and an unvented channel having a plurality of connected...
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7238268 |
Microfluidic devices for the controlled manipulation of small volumes
A method for conducting a broad range of biochemical analyses or manipulations on a series of nano- to subnanoliter reaction volumes and an apparatus for carrying out the same are disclosed. The...
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7229539 |
Destructible surfactants and uses thereof
Destructible surfactants and methods of using same are provided. The invention includes anionic surfactants having a dioxolane or dioxane functional group which enables the surfactant to be broken...
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7223325 |
Method for orthogonal analyte stacking/injection systems in electrophoresis
In the present capillary electrokinetic chromatograpy method, analytes are injected by electroosmotic flow directly from a sample matrix into a separation buffer containing an electrokinetic vector...
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7217350 |
Mobility and effects arising from surface charge
A method of, and apparatus for, automatically determining an electric charge—related characteristic or derived parameter of particles in a dispersion or of a cell wall, comprises having a...
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7214299 |
Method for separation, identification and evaluation of microbes and cells
The method entails using capillary electrophoresis or capillary isoelectric focusing to separate intact microbes. The capillary system can be a conventional capillary tube or a microfluidic device....
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7214298 |
Microfabricated cell sorter
The invention provides a microfabricated device for sorting cells based on a desired characteristic, for example, reporter-labeled cells can be sorted by the presence or level of reporter on the...
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7211184 |
Capillary electrophoresis devices
A capillary electrophoresis device as well as a process for fabrication of the device is disclosed. The capillary electrophoresis device comprises a device body structure having a plurality of...
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