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US20110106454 METHOD AND SYSTEM FOR COMPARATIVE GENOMICS  
A method and system for representing a similarity between at least two genomes that includes detecting gene clusters which are common to the at least two genomes and representing the common gene...
US20110301862 System for array-based DNA copy number and loss of heterozygosity analyses and reporting  
The problem of analyzing, visualizing an interpreting data of DNA arrays (array CGH and SNP arrays) in a clinical setting becomes very important as DNA arrays take over clinical diagnostics....
US20110224916 Fitness determination for DNA codeword searching  
An apparatus for a hybrid architecture that consists of a general purpose microprocessor and a hardware accelerator for accelerating the discovery of DNA reverse complement, edit distance codes....
US20130261024 System for Identifying Connections Between Perturbagens and Genes Associated with a Skin Hyperpigmentation Condition  
A system for identifying connections between perturbagens and genes associated with a skin hyperpigmentation condition. The system includes a computer readable medium having a plurality of...
US20150167080 METHOD OF DETERMINING CLONOTYPES AND CLONOTYPE PROFILES  
The invention is directed to methods for determining clonotypes and clonotype profiles in assays for analyzing immune repertoires by high throughput nucleic acid sequencing of somatically...
US20120171693 Methods for Generating Novel Stabilized Proteins  
The disclosure provides methods for identifying and producing stabilized chimeric proteins.
US20150066383 COLLAPSIBLE MODULAR GENOMIC PIPELINE  
The invention generally relates to tools for genomic analysis and particularly to a pipeline editor that can turn pipelines into standalone tools for use in other pipelines. The invention provides...
US20120197540 MARKERS TO PREDICT SURVIVAL OF BREAST CANCER PATIENTS AND USES THEREOF  
The present invention relates to a method to predict the mortality risk of a subject (p) affected of breast cancer comprising measuring the expression level of 105 specific genes in a biological...
US20130217011 DIAGNOSTIC BIOMARKERS OF DIABETES  
Methods are disclosed for the identification of gene sets that are differentially expressed in PBMCs of patients diagnosed with a pre-diabetic disease state and overt type II diabetes. 3 gene and...
US20150259749 METHODS FOR PRODUCING HIGH-FIDELITY AUTOLOGOUS IDIOTYPE VACCINES  
The present invention concerns methods for selecting and producing idiotype vaccines, and in particular methods for selecting and producing an idiotype vaccine for treatment of a B-cell derived...
US20140121993 CONSIDERATION OF EVIDENCE  
In many situations, particularly in forensic science, there is a need to consider one piece of evidence against one or more other pieces of evidence. For instance, it may be desirable to compare a...
US20120303287 METHODS AND SYSTEMS FOR CONSERVATIVE EXTRACTION OF OVER-REPRESENTED EXTENSIBLE MOTIFS  
Methods and systems of extracting extensible motifs from a sequence include assigning a significance to extensible motifs within the sequence based upon a syntactic and statistical analysis, and...
US20140018253 GENE EXPRESSION PANEL FOR BREAST CANCER PROGNOSIS  
The invention described in the application relates to a panel of gene expression markers for node-negative, ER-positive, HER2-negative breast cancer patients. The invention thus provides methods...
US20060136147 Biological relationship event extraction system and method for processing biological information  
A biological relationship extraction system including a biological named entity substitution unit substituting a biological named entity in a biological document with a predetermined substitution...
US20140303002 Gene Expression Profile Algorithm and Test for Determining Prognosis of Prostate Cancer  
The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a...
US20110172930 DISCOVERY OF t-HOMOLOGY IN A SET OF SEQUENCES AND PRODUCTION OF LISTS OF t-HOMOLOGOUS SEQUENCES WITH PREDEFINED PROPERTIES  
System(s) and method(s) for analysis and design of genome sequences are provided. A graph representation of a genome sequence facilitates generation of a thermodynamic based quantity, e.g., an...
US20140011879 SERUM MARKERS FOR IDENTIFICATION OF CUTANEOUS SYSTEMIC SCLEROSIS SUBJECTS  
Tools for diagnosis and management of patients suspected of having or having been previously diagnosed with systemic sclerosis are based on the determination one or more of the markers described...
US20150191777 RAPID IDENTIFICATION OF INFECTIOUS MICROORGANISMS AT POINT OF CARE  
The present invention relates to the rapid identification of the species and subspecies in a sample such as a biological sample. By collecting and using PCR primers for the collection of species...
US20120072124 GENES ASSOCIATED WITH PROGRESSION AND RESPONSE IN CHRONIC MYELOID LEUKEMIA AND USES THEREOF  
The invention provides molecular markers that are associated with the progression of chronic myeloid leukemia (CML), and methods and computer systems for monitoring the progression of CML in a...
US20110105466 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PSYCHOTIC DISORDERS THROUGH THE IDENTIFICATION OF THE SULT4A1-1 HAPLOTYPE  
Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a SULT4A1-1...
US20120258074 Systems, Models and Methods for Identifying and Evaluating Skin-Active Agents Effective for Treating Dandruff/Seborrheic Dermatitis  
Methods and systems for determining functional relationships between a skin-active agent and a skin condition of interest, and methods and systems for identifying cosmetic agents effective for...
US20120141450 RISK MARKERS FOR CARDIOVASCULAR DISEASE  
The invention relates to a method for determining the risk of suffering a cardiovascular disease based on the presence of different polymorphisms as well as to kits for practicing the above...
US20130296175 Genetic Variants as Markers for Use in Urinary Bladder Cancer Risk Assessment, Diagnosis, Prognosis and Treatment  
Polymorphic variants that have been found to be associated with risk of urinary bladder cancer are provided herein. Such polymorphic markers are useful for diagnostic purposes, such as in methods...
US20150073724 METHOD FOR FINDING VARIANTS FROM TARGETED SEQUENCING PANELS  
Provided herein is a method for identifying a sequence variant in an enriched sample. In certain embodiments, this method may comprise: (a) obtaining: (i) a plurality of sequence reads from a...
US20130237456 MARKER CONSISTING OF PLASMA MICRORNA AND A NEW METHOD FOR DIAGNOSIS OF HEPATOCELLULAR CARCINOMA  
The present invention relates to a kit for diagnosing hepatocellular carcinoma consisting of plasma microRNA, a kit containing the same, and a new method therefor. The marker for diagnosing...
US20140357660 GENE EXPRESSION SIGNATURES OF NEOPLASM RESPONSIVENESS TO THERAPY  
Gene signatures for determining whether a neoplasm (such as a multiple myeloma neoplasm) is sensitive to mTORi/HDACi combination therapy and/or for determining the prognosis of a neoplasm in a...
US20140296079 METHODS FOR EARLY DETECTION OF ESOPHAGEAL CANCER  
The present invention relates to a method for screening, predicting or prognosing esophageal adenocarcinoma/high grade dysplasia in a subject.
US20110014625 System and Method for Determining the Health of a Subject Using Polymorphic Risk Markers  
A system and method for predicting the health of a subject comprising obtaining nucleic acid sequence data about the subject. Identifying at least one polymorphic risk marker associated with a...
US20130054151 PHASING OF HETEROZYGOUS LOCI TO DETERMINE GENOMIC HAPLOTYPES  
Haplotypes of one or more portions of a chromosome of an organism from sequencing information of DNA or RNA fragments can be determined. Heterozygous loci (hets) can be used to determine...
US20150110754 High Resolution Allele Identification  
Provided herein are methods for accurately determining the alleles present at a locus that is broadly applicable to any locus, including highly polymorphic loci such as HLA loci, BGA loci and HV...
US20130309660 METHODS OF CHARACTERIZING, DETERMINING SIMILARITY, PREDICTING CORRELATION BETWEEN AND REPRESENTING SEQUENCES AND SYSTEMS AND INDICATORS THEREFOR  
A computer implemented method for characterizing one or more sequences by generating index values representing portions of the sequences and finding characterizing index values based on a...
US20130210002 METHOD OF ANALYZING CELLULAR CHROMOSOMES  
The present invention involves an analysis method of cellular chromosomes, particularly involves a method of analyzing whether a difference exists in the chromosome number between amniotic cells...
US20140336075 METHOD AND SYSTEM FOR DETERMININING WHETHER GENOME IS ABNORMAL  
The present invention provides a method and system for determining whether a genomic abnormality exists. The method for determining whether a genomic abnormality exists includes the steps of:...
US20150142334 SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR GENETIC BASE CALLING AND MAPPING  
RNA sequencing techniques provide rapid base-calling and resequencing for improved bio-informatics. Exemplary embodiments of computer-implemented systems and methods can be provided, as applied to...
US20120041686 DIAGNOSTIC FOR LUNG DISORDERS USING CLASS PREDICTION  
The present invention provides methods for diagnosis and prognosis of lung cancer using expression analysis of one or more groups of genes, and a combination of expression analysis with...
US20130273529 Identifying and Correcting An Allelic Ladder Signal For DNA Analysis  
A method for determining an allelic ladder signal for DNA analysis includes obtaining a measured allelic ladder signal for an allelic ladder substance, which includes a plurality of fragments,...
US20140378425 BIOMARKERS FOR DIAGNOSIS OF LUNG DISEASES AND METHODS OF USE THEREOF  
The present disclosure provides methods for diagnosis of interstitial lung diseases (ILDs). The present disclosure provides methods for differential diagnosis of idiopathic pulmonary fibrosis from...
US20120144508 ARTIFICIAL SELECTION METHOD AND REAGENTS  
The present invention provides methods for estimating the breeding value of individuals in populations such as those having small effective population size (Ne) e.g., to identify selection...
US20140121990 Secure Informatics Infrastructure for Genomic-Enabled Medicine, Social, and Other Applications  
A system is disclosed in which human genomes are stored in databases or in a cloud based computer system, which is secure and private and then downloaded to personal devices for possible...
US20110251798 Methods for high throughput genotyping  
Methods for genotyping polymorphisms using allele specific probes are disclosed. A training set is used to generate a model for each polymorphism to be interrogated. The training set is used to...
US20130030714 METHODS FOR THE SURVEY AND GENETIC ANALYSIS OF POPULATIONS  
The present invention relates to methods for performing surveys of the genetic diversity of a population. The invention also relates to methods for performing genetic analyses of a population. The...
US20110172929 SYSTEM AND METHOD FOR PREDICTION OF PHENOTYPICALLY RELEVANT GENES AND PERTURBATION TARGETS  
Disclosed herein is a systems biology approach to prediction of phenotypically relevant genes such as oncogenes and perturbation targets. Interactions from a comprehensive cellular network such as...
US20130096845 CUMULATIVE DIFFERENTIAL CHEMICAL ASSAY IDENTIFICATION  
An apparatus comprising: a value receiver, configured to receive fluorescence values measured during a chemical reaction involving a test sample, each value pertaining to a respective physical...
US20130273543 GENETIC VARIANTS USEFUL FOR RISK ASSESSMENT OF THYROID CANCER  
The invention discloses genetic variants that have been determined to be susceptibility variants of thyroid cancer. Methods of disease management, including methods of determining susceptibility...
US20120283958 GENERALIZED NETWORK THREADING APPROACH FOR PREDICTING A SUBJECT'S RESPONSE TO HEPATITIS C VIRUS THERAPY  
Methods for predicting a response of a virus to an antiviral therapy are provided.
US20140371078 METHOD FOR DETERMINING COPY NUMBER VARIATIONS IN SEX CHROMOSOMES  
The invention provides methods for determining copy number of the Y chromosome, including, but not limited to, methods for gender determination or Y chromosome aneuploidy of fetus using maternal...
US20130143745 COMPOSITIONS AND METHODS FOR IDENTIFYING THE ESSENTIAL GENOME OF AN ORGANISM  
Compositions and methods are provided for the rapid and highly accurate identification of the entire essential genome of any organism under a given selection condition at a resolution of a few...
US20130253847 GENETIC VARIANTS AS MARKERS FOR USE IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF EOSINOPHILIA, ASTHMA, AND MYOCARDIAL INFARCTION  
Polymorphic variants (e.g., certain alleles of polymorphic markers) that have been found to be associated with high blood eosinophil counts, conditions causative of eosinophilia (e.g., asthma,...
US20120052487 METHODS AND COMPOSITIONS FOR SELECTING SIRNA OF IMPROVED FUNCTIONALITY  
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
US20070027630 Managing biological databases  
Disclosed are compositions and methods for managing databases.