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US20140277354 SYSTEM AND STENT FOR REPAIRING ENDOVASCULAR DEFECTS AND METHODS OF USE  
Disclosed are endovascular stents in which a portion of the stents have a bioactive coating for promoting repair of damaged vessels, systems comprising the stents, and methods of using the stents...
US20150012083 TUBULAR TISSUE-ENGINEERED CONSTRUCTS  
The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially...
US20110313513 METHOD AND DEVICES FOR PREVENTING RESTENOSIS IN CARDIOVASCULAR STENTS  
Described herein are devices and methods fabricating devices having nanostructures that allow adhesion or growth of one cell type, such as endothelial cells, more than another cell type, such as...
US20150094799 Extracellular Matrix Prostheses for Treating Damaged Biological Tissue  
Mufti-sheet laminate structures having a first extracellular matrix (ECM) sheet member having a top cross-linked surface and a second ECM sheet member having a bottom surface, the second ECM sheet...
US20130172985 CROSSLINKED HYDROGELS AND METHODS OF MAKING AND USING THEREOF  
Described herein are modified gelatins or the pharmaceutically-acceptable salts or esters thereof comprising at least one actinically crosslinkable group covalently bonded to gelatin. The modified...
US20130345794 MULTILAYERED VASCULAR TUBES  
Described herein are engineered multilayered vascular tubes comprising at least one layer of differentiated adult fibroblasts, at least one layer of differentiated adult smooth muscle cells,...
US20110098799 Stent Combined with a Biological Scaffold Seeded With Endothelial Cells  
Disclosed herein are implantable medical device, and in particular, vascular stent having a biocompatible scaffold seeded with endothelial cells. The stent can provide structural support to...
US20100331964 Ex Vivo Remodeling of Excised Blood Vessels for Vascular Grafts  
The present invention provides an ex vivo vascular remodeling methods and system by which an excised, small diameter blood vessel can be harvested and expanded to provide viable vascular grafts,...
US20100305687 NON-WOVEN MAT AND METHO OF PRODUCING SAME  
A mat having a highly uniform porosity distribution is produced by consolidating 15 or more layers of melt blown webs (or the like) having different orientations. Control over the porosity is...
US20070168021 Porous three dimensional nest scaffolding  
The invention provides porous three dimensional scaffold structures that may be used to deliver a bioactive agent, such as cells, into a location within the body. In one example form, the porous...
US20080243235 CELLULAR TRANSPLANT STENT  
A cellular stent carries living therapeutic cellular material for implantation into a human or animal body and allows either localized or systemic delivery of the therapeutic products, while...
US20050107868 Scaffold for tissue engineering, artificial blood vessel, cuff, and biological implant covering member  
The invention provides a porous scaffold for tissue engineering which allows easy cell engraftment and cell culture and thus enables stable organization and an artificial blood vessel which...
US20060085063 Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering  
In one aspect, the invention relates to a synthetic conduit comprising a substantially tubular body comprising substantially circumferential polymer fibers; wherein the body has an exterior...
US20080221660 Platelet Gel for Treatment of Aneurysms  
Methods for ameliorating stent graft migration and endoleak using treatment site-specific platelet gel compositions in combination with stent grafts are disclosed. Also disclosed are platelet gel...
US20150086607 FIBER SCAFFOLDS FOR USE CREATING IMPLANTABLE STRUCTURES  
A synthetic construct suitable for implantation into a biological organism that includes at least one polymer scaffold; wherein the at least one polymer scaffold includes at least one layer of...
US20080109070 BIODEGRADABLE ELASTOMERIC SCAFFOLDS CONTAINING MICROINTEGRATED CELLS  
Described herein are elastomeric materials, and in particular porous biodegradable elastomeric materials which optionally may have microintegrated cells. Also described herein are bioprosthetic...
US20050209687 Artificial vessel scaffold and artifical organs therefrom  
An artificial vessel scaffold is provided, of biocompatible materials and capable of being coated with selected cell types. A plurality of artificial organs are provided, formed of a biocompatible...
US20080039776 DEVICES FOR ENDOSCOPIC THERAPEUTIC CELL DELIVERY  
A medical device having an elongate flexible tube extending between a proximal end and a a distal end. The device has a lumen extending between the proximal and distal ends. The lumen contains...
US20130289715 MULTILAYERED IMPLANT MATERIALS DERIVED FROM AMNIOTIC MEMBRANE, METHODS OF MAKING THE MULTILAYERED IMPLANT MATERIALS, AND METHOD OF USING MULTILAYERED IMPLANT MATERIALS  
Exemplary embodiments of the present disclosure provide for multi-layered implantation materials, methods of making a multi-layered implantation material, methods of forming a multi-layered...
US20060136047 Tissue graft prosthesis devices containing juvenile or small diameter submucosa  
Described are preferred tissue graft materials that incorporate juvenile submucosa tissue from a warm-blooded vertebrate. Preferred materials incorporate juvenile small intestinal submucosa tissue...
US20090018386 Seeding Implantable Medical Devices with Cells  
The invention is directed to apparatus and methods for seeding an implantable medical device, such as a vascular prosthesis, with cells, such as endothelial cells. The invention supports...
US20080125858 Materials and Methods For Treating and Managing Plaque Disease  
Disclosed herein are materials and methods suitable for treating and managing plaque disease, including vulnerable plaque. An implantable material comprising cells, such as but not limited to...
US20090248145 METHOD OF FORMING A THREE-DIMENSIONAL STRUCTURE OF UNIDIRECTIONALLY ALIGNED CELLS  
The present invention provides a method of forming a three-dimensional structure of unidirectionally aligned cells. The method comprises providing a substrate with a microchannel. The microchannel...
US20070208420 Functionalizing implantable devices with a poly (diol co-citrate) polymer  
The present invention is directed to a novel poly(diol citrates)-based coating for implantable devices. More specifically, the specification describes methods and compositions for making and using...
US20060286664 Bioreactor for the Manufacture of Tissue Engineered Blood Vessels  
The invention relates to bioreactors having an enclosed chamber, a sheet growth module, a rollable mandrel, and a clamp for holding the sheet to the mandrel for rolling for the manufacture of a...
US20080249616 Reinforced Porous Coating  
The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps: -providing a support having a...
US20070299508 VASCULARIZED TISSUE GRAFT  
The present invention relates generally to improved methods for tissue engineering including tissue transplantation, augmentation and regeneration. More particularly, the present invention...
US20060122695 Tissue Engineered Stents  
This invention is directed to a tissue-engineered stent comprising a substantially cylindrical construct (10) having a first end (12) and a second end (14); a walled surface (16) disposed between...
US20090105811 Intravascular Devices for Cell-Based Therapies  
Disclosed herein are vascular cell encapsulation devices that can deliver cell type(s) for the treatment of a disease or disorder.
US20080109072 MEDICAL DEVICES AND METHODS OF MAKING THE SAME  
Medical devices, such as endoprostheses, and related methods are disclosed.
US20110015723 ADJUSTABLE STENOSIS AND METHOD THEREFOR  
An adjustable stenosis provides a channel comprising an outer wall and an inner wall. The inner wall may comprise resiliently flexible material. A reservoir may be formed by the outer wall and...
US20120237560 Cardiac Compositions  
Embodiments of the present invention provide a composition comprising perivascular stem cells or induced pluripotent cells (iPS) and a NELL-1 factor for cardiac or vascular regeneration and...
US20140081384 BIOMIMETIC VASCULAR NETWORK AND DEVICES USING THE SAME  
The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid...
US20080294270 DIFFERENTIALLY PROCESSED TISSUE AND PROCESSING METHODS THEREOF  
A method of preparing an implantable biological device having a first tissue part and a second tissue part includes exposing the first tissue part to a first preparation method and preventing...
US20100204783 METHODS AND COMPOSITIONS FOR ENHANCING VASCULAR ACCESS  
Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality.
US20070202093 Systems and Methods to Reduce Gel Retraction  
Methods for ameliorating stent graft migration and endoleak using treatment site-specific cell growth promoting compositions in combination with stent grafts are disclosed. Also disclosed are...
US20070098703 Methods for Using Adipose-Derived Cells for Healing of Aortic Aneurysmal Tissue  
The present invention encompasses methods and apparatus for minimizing the risks inherent in endovascular grafting for aneurysm repair. The invention includes tracking a delivery means into an...
US20080065196 Intra-Columnar Cell Features to Improve Drug Distribution and Scaffolding of a Stent  
The present invention is directed toward a stent having a plurality of axially spaced serpentine bands, each serpentine band having an axis circumferentially oriented around the longitudinal axis...
US20090319033 METHOD FOR ENDOTHELIAL CELL EXTRACTION FROM ADISPOSE TISSUES  
Adipose tissue has proven to serve as an abundant, accessible, and rich source of endothelial or vascular endothelial cells suitable for tissue engineering. We describe a detailed method for the...
US20090028919 SYSTEMS AND METHODS OF PROMOTING ENGRAFTMENT OF A HYBRID LOWER LIMB ARTERY BYPASS VASCULAR GRAFT IN A MAMMAL  
Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments...
US20070129789 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device  
A medical device for implantation into vessels or luminal structures within the body is provided, which stimulates positive blood vessel remodeling. The medical device, such as a stent and a...
US20070269481 Biomimetic Scaffolds  
The invention provides a composition comprising a nanofiber polymer in which the fibers of the nanofiber polymer are aligned, and a molecule is covalently attached, either directly or through a...
US20080243236 Method of conditioning a hybrid synthetic tubular structure to yeild a functional human hybrid hemodialysis access graft  
A method of yielding a functional human hybrid hemodialysis access graft is provided. The method includes conditioning a hybrid synthetic tubular structure having stem cells and/or endothelial...
US20060122696 Methods and apparatus for in vivo cell therapy  
The present invention includes a method and apparatus to transplant functional cells into failing heart muscle to cure heart disease. In particular, the present invention relates to a method and...
US20090007923 SYSTEM AND METHOD FOR CONTROLLING THE DIAMETER OF A MAMMILIAN HYBRID CORONARY BYPASS GRAFT  
Systems and methods are provided for controlling the diameter of a mammalian hybrid coronary bypass graft. The system includes a controller having at least one input for receiving information and...
US20060240061 Tissue engineered blood vessels  
The invention is directed to methods for preparing artificial blood vessels by preconditioning a matrix seeded with endothelial cells to fluid flow conditions that mimic blood flow.
US20050288618 Myocardial treatment apparatus and method  
Apparatus and methods for forming a conduit through an infarcted region where the conduit is in fluid communication with a supply of oxygenated blood and the venous vasculature and flowing...
US20060258004 Cell sodding method and apparatus  
Tissue engineering methods and biochamber apparatus are provided for making tissue grafts for implantation into a patient. The methods include applying a sustained low magnitude pressure gradient...
US20050119762 Hydrogel providing cell-specific ingrowth  
A polymeric biomaterial that facilitates cell-specific ingrowth. The polymeric biomaterial encourages the ingrowth of cell types while reducing the ingrowth of undesirable cell types. This...
US20070027529 Biological artificial blood vessel and method of making  
A prosthetic device for implantation into a human body is made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate,...

Matches 1 - 50 out of 56 1 2 >