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US20120059064 Compositions and Methods For Inhibiting an Isoform of Human Manganese Superoxide Dismutase  
The present invention is directed to methods of modulating the activity of an isoform of manganese superoxide dismutase which is useful for the treatment of diseases such as neurodegenerative...
US20120259048 PROCESS FOR PRODUCING A RUBBER ANTI-AGING AGENT, A VULCANIZATION ACCELERATOR OR MODIFIED NATURAL RUBBER BY MEANS OF MICROORGANISM  
An object of the present invention is to provide processes for producing a rubber anti-aging agent, a vulcanization accelerator and a modified natural rubber, by converting glucose into benzoic...
US20120220665 Inhibiting Neurotransmitter Reuptake  
This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for...
US20150005328 Oximes For Treatment Of Peripheral And Central Nervous System Exposure to Acetyl Cholinesterase Inhibitors  
The present invention relates to non-charged oxime compounds which are acetyl cholinesterase (AChE) reactivators of inhibited AChE and which protect against organophosphate poisoning both...
US20130035351 Oximes For Treatment Of Peripheral And Central Nervous System Exposure To Acetyl Cholinesterase Inhibitors  
The present invention relates to non-charged oxime compounds which are acetyl cholinesterase (AChE) reactivators of inhibited AChE and which protect against organophosphate poisoning both...
US20120253073 METHOD FOR PRODUCING OXIME  
There is provided a method for producing an oxime compound, which is characterized by the steps of: (a) oxidizing cumene to produce cumene hydroperoxide,(b) subjecting the cumene hydroperoxide to...
US20110117141 METHODS AND COMPOSITIONS COMPRISING NOVEL CATIONIC LIPIDS  
Provided herein are novel cationic lipids, compositions comprising the cationic lipids, and methods of using the cationic lipids. In some claims, the cationic lipids have cytotoxic activity and can...
US20140271541 SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS IN THE TREATMENT OF DEMYELINATING DISORDERS  
Disclosed are pharmaceutical combinations comprising at least one S1P receptor agonist, as well as a method for treating demyelinating diseases, e.g. multiple sclerosis or disorders associated...
US20120071528 METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA  
The invention is directed to novel compounds of Formula I: as well as its stereoisomers and/or pharmaceutically acceptable salts, for the treatment of diabetes and diabetes associated dyslipidemia.
US20140017121 TERTIARY S-NITROSOTHIOL-MODIFIED NITRICOXIDE-RELEASING XEROGELS AND METHODS OF USING THE SAME  
Provided according to embodiments of the invention are novel tertiary alkyl thiol compounds and novel tertiary alkyl nitrosothiol compounds. Further provided according to embodiments of the...
US20110182799 SEQUESTRATION OF A GAS EMITTED BY AN INDUSTRIAL PLANT  
A method of sequestering a multi-element gas emitted by an industrial plant is described herein, the method comprising: contacting a solution, including a first reactant comprising a multi-element...
US20110142759 AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN  
The present invention relates to agents capable of binding to myelin basic protein in a subject. Also provided are methods for the detection of myelin-associated neuropathy comprising identifying a...
US20110288111 INHIBITION OF INFLUENZA M2 PROTON CHANNEL  
Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza...
US20120208956 BETA-HYDROXYALKYLAMIDES, A METHOD FOR PRODUCTION OF SAME AND USE OF SAME  
The invention relates to new β-hydroxyalkylamides, to a method for production of same and to the use of same.
US20110224459 Beta-hydroxyalkylamides, a method for production of same and use of same  
The invention relates to new β-hydroxyalkylamides, to a method for production of same and to the use of same.
US20120172429 PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI- INFLAMMATORY AGENTS  
The invention provides compounds, compositions, methods, and kits for the treatment of neurogenic inflammation.
US20110076214 Reversible Room-Temperature Ionic Liquids  
One aspect of the present invention relates to salts that are room-temperature ionic liquids (RTILs), methods of making them, and methods of using them in connection with temporary or permanent gas...
US20140343260 PET/SPECT AGENTS FOR APPLICATIONS IN BIOMEDICAL IMAGING  
Tracers that can be used for PET or SPECT imaging of the distribution of Pgp are disclosed. The tracers are metalloprobes that can comprise a radioactive metal ion such as 67Ga or 68Ga. Methods of...
US20110065957 SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF  
The invention relates to a composition and a method of preparing one such composition and an isocyanatoalkoxysilane; the polyisocyanate composition contains at least two different oligomeric...
US20140235872 NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY  
The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with...
US20130178541 NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY  
The instant invention provides for novel catiomc lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with...
US20130090372 Novel Low Molecular Weight Cationic Lipids for Oligonucleotide Delivery  
The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with...
US20140377345 CONTROLLED RELEASE ORAL PHARMACEUTICAL DOSAGE FORMS COMPRISING MGBG  
Disclosed herein are controlled-release oral pharmaceutical dosage forms comprising MGBG, and their application for the improved treatment of diseases with reduced side effects and/or longer time...
US20120269891 CONTROLLED RELEASE ORAL PHARMACEUTICAL DOSAGE FORMS COMPRISING MGBG  
Disclosed herein are controlled-release oral pharmaceutical dosage forms comprising MGBG, and their application for the improved treatment of diseases with reduced side effects and/or longer time...
US20140228580 METHOD FOR PURIFYING A CRUDE PNPNH COMPOUND  
The present invention relates to a method for purifying a crude PNPNH compound by metalation and re-protonation.
US20140314746 METHODS FOR TREATING OR PREVENTING FIBROSIS IN SUBJECTS AFFLICTED WITH SCLERODERMA  
The invention includes novel methods of treating or preventing fibrosis in a subject afflicted with scleroderma, comprising administering to the subject a therapeutically effective amount of an...
US20110301383 Beta-Diketiminate Ligand Sources and Metal-Containing Compounds Thereof, and Systems and Methods Including Same  
The present invention provides metal-containing compounds that include at least one β-diketiminate ligand, and methods of making and using the same. In certain embodiments, the metal-containing ...
US20120232171 Alkoxylated Cyclic Diamines And Use Thereof As Emulsion Breakers  
The invention relates to the use of alkoxylated cyclic diamines, the reactive groups of which are alkoxylated by means of at least one C2 to C4 alkylene oxide, and the average degree of...
US20150087620 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES  
The present invention provides a compound represented by the following formula (I): wherein each symbol is as described in the DESCRIPTION, which has a superior peripheral blood lymphocyte...
US20110207909 Catalytic System of Nitrate Anions for CO2/ Epoxide Copolymerization  
This invention relates to a Salen type ligand including three or more quaternary ammonium salts of nitrate anions, to a trivalent metal complex compound prepared from this ligand and a method of...
US20130157845 SORBENTS FOR REMOVING MERCURY FROM EMISSIONS PRODUCED DURING FUEL COMBUSION  
Activated carbon is rendered more thermally stable by exposure to a non-halogenated additive, and optionally to a halogen and/or a halogen-containing compound. Such treated carbon is suitable for...
US20130096348 CHIRAL DIENE LIGANDS, A FABRICATION METHOD THEREOF AND APPLICATIONS THEREOF  
The present invention proposes a chiral diene ligand, a fabrication method thereof and applications thereof. The chiral diene ligand is a bicyclo[2.2.1] diene ligand having structural specificity...
US20150139915 METHODS TO DECREASE SUSCEPTIBILITY TO ASTHMATIC BRONCHOCONSTRICTION  
Methods and compositions are described for reducing airway reactivity and the susceptibility to asthmatic bronchoconstriction that involve increasing sphingolipid content in airways and lungs of a...
US20110015201 HEDGEHOG PATHWAY ANTAGONISTS AND METHODS OF USE  
The present disclosure provides for compounds, pharmaceutical preparations, kits and methods for the inhibition of the Hh pathway and the alleviation of cancer and developmental disorders...
US20120022070 Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use  
Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors are disclosed. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases and...
US20120088162 Safe Battery Solvents  
An ion transporting solvent for use with batteries can be improved by simultaneously shortening a phosphazene compound's pendent groups, eliminating most or all of the distal ion carriers, and...
US20140329916 MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING ADIPATE, 6-AMINOCAPROATE, HEXAMETHYLENEDIAMINE OR CAPROLACTAM RELATED THERETO  
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such...
US20120130132 METHOD FOR SEPARATING N,N-DIALKYLBISAMINOALKYLETHER FROM MIXTURES COMPRISING N,N-DIALKYLBISAMINOALKYLETHER AND AT LEAST ONE OF N,N,N'-TRIALKYLBISAMINOALKYLETHER AND N,N,N',N'-TETRAALKYLBISAMINOALKYLETHER  
According to the present invention, a method for separating a primary amine being an N,N-dialkylbisaminoalkylether, from mixtures comprising said primary amine and at least one of a secondary amine...
US20110110984 Oral Dosage Form Comprising Tri-Substituted Glycerol Compounds  
The present invention relates to pharmaceutical solid dosage forms for oral administration comprising a tri-substituted glycerol compound or a pharmaceutically acceptable salt thereof. The...
US20120203102 AZULENE AND AZAAZULENE SYSTEMS FOR IMAGING, MONITORING AND THERAPY  
This invention is directed to non-benzenoid aromatic compounds. Other aspects include methods of using non-benzenoid aromatic compounds for imaging and phototherapeutic uses thereof. Non-benzenoid...
US20140314779 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION  
Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such...
US20140286927 METHOD FOR THE TREATMENT OF ULCERATIVE COLITIS IN PATIENTS REFRACTORY TO STEROID THERAPY USING LEACHED LIGAND FIBRIN STABILIZING COMPOSITION  
A engineered composition and method of delivery of said composition providing effective therapy for the treatment of ulcerative colitis, and Crohn's disease.
US20110159597 ACTIVATED PARTIAL THROMBOPLASTIN TIME MEASURING REAGENT, ACTIVATED PARTIAL THROMBOPLASTIN TIME MEASURING METHOD, AND DETERMINATION METHOD FOR DETERMINING PRESENCE OR ABSENCE OF BLOOD COAGULATION INHIBITOR  
An activated partial thromboplastin time measuring reagent, comprising a heparin neutralizer is disclosed. An activated partial thromboplastin time measuring method, and a determination method for...
US20110041732 PROCESS FOR MANUFACTURING ASPHALT  
A process for manufacturing asphalt is disclosed. The process comprises the steps of: (i) heating bitumen; (ii) heating aggregate; and (iii) mixing the hot bitumen with the hot aggregate in a...
US20140155490 THERAPEUTIC COMPOUNDS  
The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for...
US20120149693 THERAPEUTIC COMPOUNDS  
The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for...
US20100305212 THERAPEUTIC COMPOUNDS  
The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for...
US20140275270 Isolated Stereoisomeric Forms Of (S)2-N(3-O-(Propan 2-Ol)-1-Propyl-4-Hydroxybenzene)-3-Phenylpropylamide  
Isolated stereoisomeric forms of the compound (S)2-N(3-O-(propan 2-ol)-1-propyl-4-hydroxybenzene)-3-phenylpropylamide and uses in the treatment of pain.
US20110177140 4-AMIDINO BENZYLAMINES FOR COSMETIC AND/OR DERMATOLOGICAL USE  
This invention relates to the use of 4-amidino benzylamine derivatives as cosmetic ingredients and to cosmetic compositions, as well as to non-therapeutic methods for the cosmetic treatment of the...
US20150099165 ELECTROLYTE ADDITIVE FOR A LITHIUM-BASED ENERGY STORAGE DEVICE  
The invention relates to an electrolyte for a lithium-based energy storage device comprising at least one lithium salt, a solvent and at least one compound of general formula (1), and to their use...