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US20110236395 TREATMENT OF FIBROTIC EYE DISORDERS USING AN MMP2 INHIBITOR  
Inhibitors of matrix metalloproteinase 2 are used to treat or prevent a fibrotic disorder of the posterior capsule of the eye, for example posterior capsule opacification (PCO), or of a tissue or...
US20130324762 PROCESS FOR PREPARING SURFACE-REACTED CALCIUM CARBONATE AND ITS USE  
The present invention relates to an economic process for preparing surface-reacted calcium carbonate. The present invention further relates to a surface-reacted calcium carbonate having an...
US20090042987 TREATMENT OF NEUROPATHIC PAIN  
A method of decreasing neuropathic pain in a mammal, comprising administering to said mammal an effective amount of tranilast for a period of time sufficient to decrease pain.
US20050113343 Solid-state form of alendronate sodium and preparation thereof  
A new solid-state form of alendronate sodium and process for its preparation are provided. The disclosure is also directed to pharmaceutical compositions containing the solid-state form, and to...
US20120238638 BIOLOGICAL BIOCIDE ADDITIVES FOR POLYMERS  
This invention pertains to a method of modifying biocides obtained from biological sources, namely polyphenols. The modified biocide may have protective groups to reduce or prevent the oxidation...
US20110004016 METHOD FOR THE PRODUCTION OF AMINODICARBOXYLIC ACID-N,N-DIACETIC ACIDS  
The present invention relates to a method for the production of aminodicarboxylic acid-N,N,diacetic acids of the general Formula I, wherein X independently of one another represents hydrogen or an...
US20120225940 Use of (-) (3-Trihalomethylphenoxy) (4-Halophenyl) Acetic Acid Derivatives for Treatment of Insulin Resistance, Type 2 Diabetes, Hyperlipidemia and Hyperuricemia  
The present invention provides the use of (−) (3-trihalomethylphenoxy) (4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes,...
US20110171296 METHOD AND PREPARATION FOR BINDING ACETALDEHYDE IN SALIVA, THE STOMACH AND THE LARGE INTESTINE  
The object of the invention is the use of compounds comprising one or more free sulphhydryl or amino groups for preparing a pharmaceutical composition for locally binding acetaldehyde in saliva,...
US20120190887 Processes for preparing pharmaceutical grade melphalans from industrial grade reactants  
A four stage inexpensive method of preparing pharmaceutical grade Melphalans of Melphalan 2-HCl, Melphalan HCl and Melphalan by: reacting N- phthaloyl-4-[bis(2-hydroxyethyl)amino]-phenylalanine...
US20150202332 LABELED MOLECULAR IMAGING AGENTS AND METHODS OF USE  
Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting...
US20130071332 LABELED MOLECULAR IMAGING AGENTS AND METHODS OF USE  
Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting...
US20060106107 L-tartrate salt of N-1-Adamantyl-2-{3-[(2R)-2-({(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl}amino)propyl] phenyl}acetamide  
This invention relates to the L-tartrate salt of N-1-Adamantyl-2-{3-[(2R)-2-({(2R)-2-hydroxy-2-[4-hydroxy-3-( hydroxymethyl)phenyl]ethyl}amino)propyl]phenyl}acetamide and its use as a medicament.
US20150065748 PROCESS FOR SEPARATING ARYL CARBOXYLIC ACIDS  
In the present disclosure, a process for separating aryl carboxylic acids from a mixture comprising a plurality of aryl carboxylic acids is provided, wherein the process comprising the steps of...
US20060287392 GABAPENTIN COMPOSITIONS  
The present invention comprises an organic acid salt of gabapentin, wherein the organic acid is tartaric acid, ethanedisulfonic acid, or maleic acid. Methods for modulating the solubility and dose...
US20140128622 Process for the Oxidation of Organic Carbonyl Compounds  
A process for the oxidation of an organic carbonyl compound comprising reacting the organic carbonyl compound, optionally in the presence of a solvent, with hydrogen peroxide in the presence of a...
US20140256983 METHOD OF OXIDATION USING NITRIC ACID  
A controlled nitric acid process employing oxygen and nitric acid as co-oxidants is used to oxidize organic compounds subject to nitric acid oxidation, to their corresponding carboxylic acids....
US20060004102 Polymorphic forms of nateglinide  
Provided are crystalline forms of nateglinide and processes for their preparation.
US20150152046 IMINO COMPOUNDS AS PROTECTING AGENTS AGAINTS ULTRAVIOLET RADIATIONS  
The present invention relates to compounds having the general Formula I: which absorb UV radiations and protect biological materials as well as non-biological materials from damaging exposure to...
US20140228530 Extended Surfactant For Emulsion Polymerization  
An extended anionic surfactant having the general formula: RO—(PO)n—YZ wherein R is a linear alkyl chain ranging from C6 to C36, a branched alkyl chain ranging from C6 to C36, or a mixture...
US20070043234 Use of functionalized onium salts as a soluble support for organic synthesis  
The invention relates to the use of a onium salt functionalized by at least one organic function, as a soluble support, in the presence of at least one organic solvent, for organic synthesis of a...
US20130130971 Method for Inhibiting HIV Replication in Mammal and Human Cells  
The present invention describes a method to inhibit replication of the human immunodeficiency virus (HIV) by negatively modulating or altering the cytoskeleton, more precisely the proteins forming...
US20110136877 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS  
The present invention provides novel phenoxyacetic acids useful for the prevention and treatment of inflammatory disorders, including those affecting the respiratory system and skin. The compounds...
US20140378529 COLLATERAL GENE INACTIVATION BIOMARKERS AND TARGETS FOR CANCER THERAPY  
Methods for treating a subject determined to have a cancer comprising a heterozygous inactivation of a housekeeping gene (or a homozygous deletion of a functionally redundant housekeeping gene) by...
US20050090652 Highly homogenous serum albumin as chiral selector  
The present invention provides the use of highly homogeneous serum albumin as a chiral selector, preferably immobilised, such as in enantioselective chromatography. The present invention also...
US20110144037 Substrates and Inhibitors of Antiplasmin Cleaving Enzyme and Fibroblast Activation Protein and Methods of Use  
The presently disclosed and claimed inventive concepts include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies...
US20130030215 Methods for Producing Isomers of Muconic Acid and Muconate Salts  
A method for producing cis,trans- and trans,trans-isomers of muconate by providing cis,cis-muconate produced from a renewable carbon source through biocatalytic conversion; isomerizing...
US20110034724 METHOD FOR PREPARING A TRIFLUOROMETHANESULFINIC ACID SALT  
The present invention relates to a method for preparing a salt of trifluoromethanesulphinic acid termed “triflinic acid”. More specifically, the invention relates to a method for preparing a...
US20110110886 SMALL MOLECULE INHIBITORS OF AUTOTAXIN AND METHODS OF USE  
Autotaxin (ATX) is a prometastatic enzyme initially isolated from the conditioned media of human melanoma cells that stimulates a myriad of biological activities including angiogenesis and the...
US20070081941 F-18 Labeled Amino Acid Analogs  
The present invention relates to Halogenated amino acid analogues for use in diagnosis, which compounds have the general formula wherein: R is (C1-C6)alkyl optionally substituted with thioether or...
US20100121101 Methanol carbonylation with improved aldehyde removal  
Methanol carbonylation with improved aldehyde removal includes: (a) scrubbing light ends and aldehyde impurity from vent gas with an absorber solvent; (b) stripping absorbed light ends and...
US20150087521 UNSATURATED FATTY ALCOHOL DERIVATIVES FROM NATURAL OIL METATHESIS  
Sulfate and sulfonate derivatives of unsaturated fatty alcohols, processes for making them, and methods of using them are disclosed. In one aspect, a monounsaturated fatty alcohol composition is...
US20120289741 METHOD FOR PRODUCING CATALYST FOR USE IN PRODUCTION OF UNSATURATED ALDEHYDE AND/OR UNSATURATED CARBOXYLIC ACID, AND METHOD FOR PRODUCING UNSATURATED ALDEHYDE AND/OR UNSATURATED CARBOXYLIC ACID  
A catalyst for use in the production of an unsaturated aldehyde and/or an unsaturated carboxylic acid, the catalyst comparing (or, preferably, being composed of) a mixed oxide containing...
US20140371310 MANDELIC ACID CONDENSATION POLYMERS  
Disclosed herein are compounds and compositions useful for reducing the risk of infection. In particular, disclosed herein are mandelic acid condensation polymers, compositions comprising such...
US20120003475 Synthesis Methodology to Produce Nano Metal Organic Framework Crystals  
A method for synthesizing particulate or loosely agglomerated nano-metal organic framework crystals having an average particle size less than 100 nm. A base compound is added to a solution of a...
US20130157840 Molecular Sieve Composition From Pre-Formed Extrudates and Process of Use  
This disclosure provides a molecular sieve composition having a first and second crystalline molecular sieve, made by the method comprising: (a) providing a reaction mixture comprising at least...
US20140316160 Catalyst For Methacrylic Acid Production And Process For Producing Methacrylic Acid  
There is provided a hetero polyacid-based catalyst for methacrylic acid production, which is more excellent in performance, life and moisture absorption during storage, the catalyst being a...
US20090069184 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides  
What is described are 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles of the general formula (I) and their use as herbicides. In this formula (I), R1, R2, R3 and R4 are radicals such as hydrogen and...
US20100056823 PREPARATION OF METALLIC DIHYDROXYBENZENEDISULFONATES  
Metallic dihydroxybenzenedisulfonates are prepared, preferably from alkaline metals, from corresponding dihydroxybenzenedisulfonic acids, by reacting the dihydroxybenzenedisulfonic acid present in...
US20130204033 ANTIPROLIFERATIVE COMPOUNDS, CONJUGATES THEREOF, METHODS THEREFOR, AND USES THEREOF  
Antiproliferative compounds having a structure represented by formula (II), where n, R1, R2, R3, R4, and R5 are as defined herein, can be used to treat tumors, optionally when conjugated to a...
US20130197259 ANTIPROLIFERATIVE COMPOUNDS, CONJUGATES THEREOF, METHODS THEREFOR, AND USES THEREOF  
Antiproliferative compounds having a structure represented by formula (II), where n, R1, R2, R3, R4, and R5 are as defined herein, can be used to treat tumors, optionally when conjugated to a...
US20120302765 METHOD TO PRODUCE, RECOVER AND CONVERT FURAN DERIVATIVES FROM AQUEOUS SOLUTIONS USING ALKYLPHENOL EXTRACTION  
Described is a catalytic process for converting biomass to furan derivatives (e.g., furfural, furfuryl alcohol, etc.) using a biphasic reactor containing a reactive aqueous phase and an organic...
US20080287704 PREPARATIVE-SCALE SEPARATION OF ENANTIOMERS OF CHIRAL CARBOXYLIC ACIDS  
High yields and purity are obtained in the purification of enantiomers of chiral carboxylic acids by preparative-scale chromatography by including a tertiary alcohol in the mobile phase in...
US20110144377 PROCESS FOR THE BIOLOGICAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID WITH HIGH YIELD  
The present invention provides a microorganism useful for biologically producing 3-hydroxypropionic acid from a fermentable carbon source. Further, the microorganism comprises disruptions in...
US20140088125 USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE  
Salts of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium, method of preparation thereof and use in the treatment of cardiovascular disease.
US20150038708 SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN  
In one aspect, the invention relates to substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs, derivatives thereof, and related compounds, which are useful as inhibitors of...
US20130225621 SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN  
In one aspect, the invention relates to substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs, derivatives thereof, and related compounds, which are useful as inhibitors of...
US20150203431 PROCESS FOR CONTINUOUS RECOVERING (METH)ACRYLIC ACID AND APPARATUS FOR THE PROCESS  
This disclosure relates to a method of continuous recovery of (meth)acrylic acid and an apparatus used for the continuous recovery method. The continuous recovery method of (meth)acrylic acid...
US20050288369 Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same  
The present invention relates to novel n-hydroxythiourea, urea and amide compounds as a potent vanilloid receptor antagonist and the pharmaceutical compositions comprising the same. The inventive...
US20150148562 Removal of Aromatics from Carbonylation Process  
The invention relates to processes for removing aromatics from the reactants that are fed to a carbonylation reactor. The aromatics are removed using a guard bed that comprises an adsorbent.
US20120283472 Removal of Aromatics from Carbonylation Process  
The invention relates to processes for removing aromatics from the reactants that are fed to a carbonylation reactor. The aromatics are removed using a guard bed that comprises an adsorbent.