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US20110245537 L-carnitine calcium fumarate, preparation method and application for the same  
L-carnitine calcium fumarate and its preparation and applications are disclosed in the present invention. Having good water solubility as well as better and stronger nutritious and treating...
US20120157392 Epilepsy treatment employing ketogenic compounds which arrest apoptosis  
Method of treating a patient suffering from apoptosis of tissue by administering to the patient a therapeutically effective amount of one or more ketogenic compounds such that a physiological...
US20140350107 Use of Pan-PPAR Agonists for Prevention and Treatment of Huntington's Disease and Tauopathies  
The present invention provides a therapeutic treatment for a neurodegenerative disease with a pan-PPAR agonist, such as bezafibrate. In particular, the present invention provides that pan-PPAR...
US20120041178 Coenzyme Q10 Nanoparticles, Preparation Method Thereof and Composition Containing Said Nanoparticles  
Provided are a coenzyme Q10 nanoparticle, a method of preparing the same and a composition having the nanoparticle. According to the present invention, Coenzyme Q10 may be dissolved in only a...
US20130256228 USE OF NOVEL DRAW SOLUTES AND COMBINATIONS THEREOF TO IMPROVE PERFORMANCE OF A FORWARD OSMOSIS SYSTEM AND PROCESS  
This disclosure describes draw solution compositions for FO processes which increase the available membrane area for permeation and are also amenable to reconcentration with standard techniques,...
US20130095520 METHOD FOR DETECTION OF UROTHELIAL CANCER  
It is to provide a method for detecting urothelial cancer simply and with high accuracy. It is a method for detecting urothelial cancer comprising administering 5-aminolevulinic acid (ALA), a...
US20120244627 Methods for Quantifying Vitamin D Metabolites by Mass Spectrometry  
Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise associating an amine with a...
US20130281387 Chemosensory Receptor Ligand-Based Therapies  
Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a...
US20140041062 GENETICALLY ENGINEERED MOUSE MODEL FOR AUTISM SPECTRUM DISORDER HAVING DELETION OF SHANK2 GENE AND USE THEREOF  
The present disclosure relates to an ASD genetically engineered model carrying a deletion of Shank2 gene and having reduced NMDA receptor function. According to the present disclosure, genetically...
US20080161604 Acetyl L-Carnitine For Preventing Painful Peripheral Diabetic Neuropathy  
The use of acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is described for the preparation of a medicament useful for the prevention of painful peripheral neuropathy in...
US20140308666 DEVELOPMENT OF NOVEL DETERGENTS FOR USE IN PCR SYSTEMS  
This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for...
US20120322066 Development of Novel Detergents for Use in PCR Systems  
This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for...
US20130005780 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS OF TAPENTADOL  
The present invention provides atazanavir sulfate substantially free of diastereomeric impurities. The present invention also provides atazanavir sulfate having D-tertiary leucine analogues less...
US20120201762 ORAL CARE COMPOSITION  
Disclosed are oral care compositions and the use of such oral care compositions for treating or preventing oral malodor. Also disclosed are methods for treatment or prevention of oral malodor. The...
US20140121254 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF MOVEMENT DISORDERS  
The invention provides a pharmaceutical composition, medical food, dietary supplement or micronutrient for the treatment of a movement disorder comprising an NMDAR agonist or partial agonist as...
US20150126775 PROCESS FOR THE PRODUCTION OF CARNITINE FROM BETA-LACTONES  
The invention relates to a method for the production of L-carnitine, wherein a β-lactone, which is a 4-(halomethyl)oxetane-2-one, is converted into carnitine with trimethylamine (TMA), wherein the...
US20110263897 PREPARATION METHOD OF HIGH-PURITY L-CARNITINE  
The present invention relate to a preparation method of high-purity L-carnitine which belongs to an important technique of quality control in different steps of chiral medicine production. The...
US20120316359 Biological Buffers with Wide Buffering Ranges  
Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or...
US20130123144 TUNABLE LCST POLYMERS AND METHODS OF PREPARATION  
Polymer compositions having the chemical structure: as well as monomer compositions for producing said polymers are described. Methods for preparing these polymers and combinatorial libraries of...
US20140243282 METHODS AND COMPOSITIONS FOR DESIGNING NOVEL CONJUGATE THERAPEUTICS  
The present invention relates to novel drug conjugates, where in two drugs are linked together through an appropriate linker having at least two functional groups capable of forming covalent bond...
US20140378529 COLLATERAL GENE INACTIVATION BIOMARKERS AND TARGETS FOR CANCER THERAPY  
Methods for treating a subject determined to have a cancer comprising a heterozygous inactivation of a housekeeping gene (or a homozygous deletion of a functionally redundant housekeeping gene) by...
US20120088269 SOLUTION FOR CELL-FREE PROTEIN SYNTHESIS, KIT FOR CELL-FREE PROTEIN SYNTHESIS, AND METHOD OF PROTEIN SYNTHESIS  
This invention enables synthesis of proteins that were difficult to synthesize via a conventional cell-free protein synthesis system and increases the amount of proteins synthesized. Cell-free...
US20080159954 METAL CHELATES HAVING A PERFLUORINATED PEG RADICAL, PROCESSES FOR THEIR PREPARATION, AND THEIR USE  
The invention relates to the subjects characterized in the patent claims, namely metal chelates having a perfluorinated PEG radical, processes for their preparation, and their use, processes for...
US20090137670 Amino Acid Compounds  
Carnitine and Taurine Compounds are described. The Carnitine Compound comprises Carnitine and one of a Nitrate and a Nitrite. The Taurine Compound comprises Taurine and one of a Nitrate and a Nitrite.
US20130116321 COMPOSITION CONTAINING SERINE AS AN ACTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF FATTY LIVER DISEASES, AND THE USE THEREOF  
The present invention is related to a composition comprising a serine as an active ingredient for treating or preventing fatty liver diseases. The inventive compound significantly inhibits the...
US20090048147 NITROGEN-BASED LINKERS FOR ATTACHING MODIFYING GROUPS TO POLYPEPTIDES AND OTHER MACROMOLECULES  
The present invention relates to a compound comprising a peptide moiety, a linker moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety. The linker moiety is between the...
US20090112019 METHOD FOR PRODUCING BETA-HYDROXY AMINO ACID AND ENZYME USED THEREFOR  
A method for producing β-hydroxy amino acid and its optically-active isomer is provided. The β-hydroxy amino acid is produced by reacting a predetermined D-α-amino acid and 5,10-methylene...
US20110046195 Non-Lactone Carbocyclic and Heterocyclic Antagonists and Agonists of Bacterial Quorum Sensing  
Compounds which modulate quorum sensing in quorum sensing bacteria. Compounds of the invention inhibit quorum sensing and/or activate quorum sensing in various bacteria. Compounds that inhibit...
US20100087534 Use of a Photosensitizing Agent in the Treatment or Prevention of an Inflammation-Associated Disorder in the Gastrointestinal Tract of a Mammal  
The present invention relates generally to the field of Photodynamic therapy (PDT) and more particularly to the use of a photosensitizing agent for the preparation of a medicament for the...
US20120022275 PROCESS FOR THE PRODUCTION OF CARNITINE BY CYCLOADDITION  
The invention relates to a method for the production of L-carnitine, wherein a chiral β-lactone carnitine precursor is obtained by a [2+2] cycloaddition of ketene with an aldehyde X—CH2—CHO,...
US20120058057 Anti-dandruff Agents  
The present invention relates to special ammonium carboxylates, their synthesis and application, particularly as anti-dandruff agents.
US20140257169 USE OF PHOTOSENSITIZER IN PREPARATION OF VIRUS-INACTIVATING MEDICAMENTS FOR TREATING DISEASES  
The invention relates to the field of medicament use, in particular to the clinical use of photosensitizers for inactivating viruses in the treatment of blood vessel plaque, leukemia, AIDS,...
US20090247636 AGENT FOR SUPPRESSION OF GASTRIC EMPTYING COMPRISING 4-HYDROXYISOLEUCINE  
The present invention aims to provide a more effective gastric emptying suppressant and food intake suppressant, wherein the solving means are a gastric emptying suppressant containing...
US20100120917 BUTYLAMMONIUM MODULATORS OF FATTY ACID TRANSPORT  
The present invention relates to new butylammonium modulators of fatty acid transport, and/or removal of toxic acyl-CoA compounds, pharmaceutical compositions thereof, and methods of use thereof
US20120004459 SYNTHESIS OF RARE EARTH METAL EXTRACTANT  
A rare earth metal extractant in the form of a dialkyl diglycol amic acid is synthesized by reacting diglycolic anhydride with a dialkylamine in an aprotic polar solvent, with a molar ratio of...
US20120183614 POLYPHENOL COMPOUND ABSORPTION PROMOTER AND UTILIZATION OF SAME  
Provided are a polyphenol compound absorption promoter which is widely applicable to foods and drinks over a wide range, and a method for producing a food, drink or food material containing a...
US20130123534 METHOD FOR SYNTHESIZING RARE EARTH METAL EXTRACTANT  
A rare earth metal extractant containing, as the extractant component, dialkyldiglycol amide acid which is excellent in breaking down light rare earth elements is reacted in diglycolic acid (X...
US20090281347 METHOD FOR PRODUCING AMINO ACID PHOSPHATES  
To provide a production method of phosphates of amino acids, typified by δ-aminolevulinic acid phosphate, or esters thereof. A method for producing phosphates of an amino acid or an ester thereof,...
US20150198619 STRUCTURE OF INSULIN IN COMPLEX WITH N- AND C-TERMINAL REGIONS OF THE INSULIN RECEPTOR ALPHA-CHAIN  
The present invention relates to the crystal structure of the insulin receptor ectodomain in complex with human insulin and to methods of using the crystal and related structural information to...
US20090325246 PROCESS FOR PRODUCTION OF BETAINE  
According to the present invention, by using 4-halogeno-3-hydroxybutanamide as a substrate in quaternary amination reaction with trialkylamine which is an important step in betaine (such as...
US20110130350 SYNTHESIS SCHEME FOR LACOSAMIDE  
The present invention is concerned with an improved method of producing (R)-2-acetamido-N-benzyl-3-methoxypropionamide (lacosamide) comprising the 0-methylation of a compound of formula (I) to...
US20140288172 ERYTHROPOIETIN PRODUCTION-PROMOTING AGENT  
A therapeutic and/or prophylactic agent for renal anemia comprising ALAs and an erythropoietin production promoter comprising ALAs.
US20140343150 NOVEL PHYTOSPHINGOSINE DERIVATIVES, AND COMPOSITION COMPRISING SAME FOR PREVENTING AND TREATING INFLAMMATORY SKIN DISEASES, AUTOIMMUNE DISEASES, AND HYPERKERATOSIS DISEASES  
A phytosphingosine derivative of chemical formula IA or IB, and a composition comprising the phytosphingosine derivative for preventing and treating inflammatory skin diseases, autoimmune...
US20090118515 PROCESS FOR PREPARING INTERMEDIATES USEFUL TO PREPARE CERTAIN ANTIBACTERIAL N-FORMYL HYDROXYLAMINES  
The present invention is directed to a process for preparing intermediates that are useful to prepare certain antibacterial N-formyl hydroxylamine compounds which are peptide deformylase inhibitors.
US20070225518 5-Aminolevulinic acid salts and their use  
The invention provides salts of 5-Aminolevulinic acid (ALA) of formula (I): wherein RY is an organic acid moiety; Y is selected from the group consisting of a sulfonic acid residue, mono- or...
US20090234011 N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS  
Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and therapies for human and non-human mammalian diseases, disorders,...
US20100036158 NOVEL PROCESS FOR PREPARING 3-AMINO-5-FLUORO-4-DIALKOXYPENTANOIC ACID ESTER  
The present invention relates to a novel process for the production of 3-amino-5-fluoro-4-dialkoxypentanoic acid ester used in the precursor of 3-amino-5-fluoro-4-oxopentanoic acid, represented by...
US20110245338 CHIRAL INTERMEDIATE, PROCESS FOR PRODUCING THE SAME AND ITS USE IN THE MANUFACTURE OF TOLTERODINE, FESOTERODINE, OR THE ACTIVE METABOLITE THEREOF  
The compound of formula (I): is provided. It may be produced by subjecting a compound of formula (IV) to a reduction reaction wherein R represents hydrogen, straight or branched C1-C6 alkyl. This...
US20050209328 Alphahydroxyacids with ultra-low metal concentration  
A composition and a process for producing the composition are disclosed. The composition comprises an alphahydroxyacid and one or more metals in which the metal is present in lower than about...
US20110196033 PROPHYLACTIC/AMELIORATING AGENT FOR ADULT DISEASES COMPRISING 5-AMINOLEVULINIC ACID, DERIVATIVE OF 5-AMINOLEVULINIC ACID, OR SALT OF 5-AMINOLEVULINIC ACID OR THE DERIVATIVE OR 5-AMINOLEVULINIC ACID AS ACTIVE INGREDIENT  
It is to provide a pharmaceutical composition which is different from an existing therapeutic agent of an adult disease, of a biochemical reaction-inhibiting type, and which action mechanism is to...

Matches 1 - 50 out of 108 1 2 3 >