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US20130172294 Treatment with VB-201  
Unit dosage forms comprising between 1 mg and 100 mg VB-201 and a pharmaceutically acceptable carrier, and formulated for oral administration, are disclosed herein, as well as treatment regimens...
US20120009133 POLY (NON-CONJUGATED DIENE) BASED SUNSCREENS  
A poly(non-conjugated diene) based sunscreen has a plurality of repeating units where each repeating unit has at least one UV absorbing chromophore that is situated between and connected by chains...
US20110245526 Process of Extracting Isothiocyanates  
A process for producing an essential oil. The essential oil can be white mustard essential oil. The white mustard essential oil can include a moisture sensitive isothiocyanate compound. The...
US20120288569 PARENTERAL ADMINISTRATION OF PYROPHOSPHATE FOR PREVENTION OR TREATMENT OF PHOSPHATE OR PYROPHOSPHATE DEPLETION  
Phosphate depletion, a physiological condition commonly seen in certain patient populations, including alcoholics, malnourished, acutely ill patients, patients receiving parenteral nutrition,...
US20150119364 BORON-CONTAINING SMALL MOLECULES  
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to...
US20150065459 BORON-CONTAINING SMALL MOLECULES  
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to...
US20140221631 BORON-CONTAINING SMALL MOLECULES  
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to...
US20130244980 BORON-CONTAINING SMALL MOLECULES  
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to...
US20120289686 BORON-CONTAINING SMALL MOLECULES  
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to...
US20110189212 OXIDIZED LIPIDS AND USES THEREOF IN THE TREATMENT OF INFLAMMATORY DISEASES AND DISORDERS  
Novel synthetic oxidized lipids and methods utilizing oxidized lipids for treating and preventing an inflammation associated with an endogenous oxidized lipid are provided.
US20080188556 Water-Soluble Prodrugs of Florfenicol and its Analogs  
The present invention discloses certain novel prodrugs of florfenicol and/or of florfenicol analogs, including prodrugs of salts pharmaceutically acceptable salts of florfenicol and its analogs,...
US20120264719 DOSAGE REGIMEN OF AN S1P RECEPTOR MODULATOR  
S1P receptor modulators are administered following a dosage regimen providing a positive benefit-risk profile.
US20120283224 CHEMICAL STRUCTURE COMPRISING PHOSPHATES WITH POLYOL SUBSTRUCTURES FOR HAIR AND SKIN COSMETICS USAGE  
A composition suitable for application to hair and/or skin comprises Phosphates Esters, such as Xylitol Phosphate Esters and other Polyol Units Phosphoric Acid Esters. This composition can be used...
US20120130115 METHODS OF PRODUCING NITRATE ESTERS  
Methods of forming a nitrate ester include combining at least one nitrate salt and sulfuric acid to form a nitrating solution and adding an aliphatic polyol to the nitrating solution. Nitrate...
US20120178704 PREVENTION AND TREATMENT OF COLON CANCER  
Stilbene compounds for the prevention and treatment of colon cancer or colon inflammation and methods of using same are provided.
US20150018563 Surfactants and Solvents Containing Diels-Alder Adducts  
Surfactants and solvents containing derivatized adducts formed from Diels-Alder reactions of terpenes and unsaturated carboxylic acids or their derivatives are disclosed. Processes for making and...
US20120148690 SKIN BARRIER FUNCTION RECOVERY ACCELERATOR  
A novel skin barrier function recovery acceleration method and accelerator are provided. The present invention provides a skin barrier function recovery accelerator that comprises a TRPA1 agonist...
US20100312003 METHOD FOR THE PREPARATION OF ORGANIC NITRATES  
The present invention relates to a process for the preparation of organic nitrates having at least one nitryloxy and at least one hydroxy group, wherein the at least one hydroxy group may be...
US20110217262 Treatment of Ocular Surface Disorders by Increasing Conjunctival Vascular Permeability  
A method of treating an ocular surface disorder in a subject in need of such treatment is provided. The method includes exposing conjunctival tissue of the subject to an effective amount of a...
US20120196894 NOVEL TRPA1 ANTAGONISTS  
The present invention relates to compositions and methods that modulate at least one TRP family member. Specifically, the present invention relates to novel TRPA1 antagonists and their use in the...
US20110152218 CRYSTALLINE PHOSPHOLIPID, METHOD FOR ITS PRODUCTION AND USE IN TREATING DAMAGED TISSUE  
The present invention provides phospholipid in a crystalline form, a method for its preparation, compositions comprising it and its use in the treatment of damaged tissue.
US20120208917 Dental restorative material based on an antimicrobially active compound  
The invention relates to a dental restorative material which comprises (a) at least one antimicrobially active compound of Formula (I) [AG]m-R1—Z—SP—Y—R2—[WG]p (I), or a filler that is...
US20100324325 METHOD FOR PRODUCING ANION SURFACTANT GRANULES  
Disclosed is a method for producing an anionic surfactant powder, which comprises a step wherein an aqueous anionic surfactant solution having an anionic surfactant concentration of 0.01-40% by...
US20140296223 METHOD FOR REGULATING SKIN PIGMENTATION  
This invention relates to a method for regulating skin pigmentation of a subject, comprising the step of administering the agent for inhibiting the expression or activation of Microphthalmia...
US20110030587 AGGLOMERATED PARTICULATE LIGNOSULFONATE  
An agglomerated particulate lignosulfonate material may be made by introducing or forming lignosulfonate microparticles in a fluidized bed agglomerator, and introducing sufficient heated gas and...
US20120329757 Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis  
Novel synthetic forms of etherified oxidized phospholipids and methods of utilizing same for preventing and treating atherosclerosis and other related disorders, as well as inflammatory disorders,...
US20110097350 METHODS EMPLOYING AND COMPOSITIONS CONTAINING DEFINED OXIDIZED PHOSPHOLIPIDS FOR PREVENTION AND TREATMENT OF ATHEROSCLEROSIS  
Novel synthetic forms of etherified oxidized phospholipids and methods of utilizing same for preventing and treating atherosclerosis and other related disorders, as well as inflammatory disorders,...
US20110028421 Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals  
The invention relates to the use of alkylphosphocholines in combination with antimetabolites for the treatment of multiple myeloma, colon cancer or renal cancer. Preferred alkylphosphocholines are...
US20110207956 INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES  
A highly effective Co(II)-based system has been developed for catalytic intramolecular C—H amination with phosphoryl azides without the need of terminal oxidant or other additives, resulting in...
US20110166374 METHOD FOR PRODUCING ANIONIC SURFACTANT  
Disclosed is the method for producing an anionic surfactant powder, including removing impurities by introducing gas into a crude anionic surfactant containing water in a content of 0.01 to 5% by...
US20130035304 SMALL MOLECULES FOR THE MODULATION OF MCL-1 AND METHODS OF MODULATING CELL DEATH, CELL DIVISION, CELL DIFFERENTIATION AND METHODS OF TREATING DISORDERS  
This invention relates to compounds which selectively bind to the survival protein MCL-1 with high affinity and selectivity, pharmaceutical compositions containing such compounds and the use of...
US20130261133 Therapeutic Compounds for Protozoal and Microbial Infections and Cancer  
The compounds of the invention exhibit antiprotozoal, antimicrobial, and anticancer properties that are useful for the treatment or prevention of infections or cancer in a patient (e.g., a human)....
US20140296241 THE USE OF (2R, 6R)-HYDROXYNORKETAMINE, (S)-DEHYDRONORKETAMINE AND OTHER STEREOISOMERIC DEHYDRO AND HYDROXYLATED METABOLITES OF (R,S)- KETAMINE IN THE TREATMENT OF DEPRESSION AND NEUROPATHIC PAIN  
The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite....
US20150191467 AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME  
The present invention provides new compounds of formula I, II or III, which have Src homology-2 containing protein tyrosine phosphatase-1 (SHP-1) agonist activity. Also provided are treatment...
US20140200239 AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME  
The present invention provides new compounds of formula I, II or III, which have Src homology-2 containing protein tyrosine phosphatase-1 (SHP-1) agonist activity. Also provided are treatment...
US20150133405 Methods  
The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control...
US20120108548 MOLECULAR TWEEZERS FOR THE TREATMENT OF AMYLOID-RELATED DISEASES  
This invention provides novel compositions to inhibit the aggregation of amyloid proteins. In various embodiments the compositions comprise a molecular tweezers that binds lysine and/or arginine...
US20130296230 METHOD FOR TREATING MALARIA, METHOD FOR KILLING MALARIA PARASITE, AND USE OF THE METHODS  
A method of the present invention for treating malaria includes the step of administering, to a human or an animal, a therapeutically effective amount of drug for suppressing calcium ion exit from...
US20110159054 NANOPARTICULATE BICALUTAMIDE FORMULATIONS  
The present invention is directed to compositions comprising an acylanilide, such as bicalutamide, having improved solubility in water. The bicalutamide particles of the composition have an...
US20150030683 FORMULATIONS AND METHODS FOR THE TREATMENT OR PROPHYLAXIS OF PRE-MCI AND/OR PRE-ALZHEIMER'S CONDITIONS  
In certain embodiments the methods of preventing or delaying the onset of a pre-Alzheimer's condition and/or cognitive dysfunction, and/or ameliorating one or more symptoms of a pre-Alzheimer's...
US20150073170 KINETIC RESOLUTION  
Whilst methodologies for the Kinetic Resolution of alcohols are well established, no analogous direct methods exist for the highly selective, direct catalytic Kinetic Resolution of thiols (i.e.,...
US20120277437 KINETIC RESOLUTION  
Whilst methodologies for the Kinetic Resolution of alcohols are well established, no analogous direct methods exist for the highly selective, direct catalytic Kinetic Resolution of thiols (i.e.,...
US20110065762 METHODS OF USE OF ANTIVIRAL COMPOUNDS  
The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel...
US20110218176 Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development  
The present invention relates to prevention of congenital deformations. The invention further relates to cancer inhibition and prevention. The invention further relates to methods and compositions...
US20120065152 PRODRUGS OF GUANFACINE  
Prodrugs of guanfacine, pharmaceutical compositions containing such prodrugs and a method for providing therapeutic benefit in the treatment of ADHD/ODD (attention deficient hyperactivity disorder...
US20110130349 Compounds and Methods for Treating Toll-Like Receptor 2-Related Diseases and Conditions  
The present invention relates to compounds and methods useful in the prevention or treatment of diseases or conditions associated with Toll-like receptor 2 activation.
US20120282629 Enhancers of Protein Degradation  
The present invention relates to compounds suitable for modulating huntingtin protein processing and useful for treating or preventing huntingtin-related disorders. The invention provides...
US20110250300 COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF DISORDERS RELATING TO OXIDATIVE STRESS  
The present invention features methods for treating or preventing conditions, diseases, or disorders related to oxidative stress. In one embodiment, the method increases Nrf2 biological activity...
US20120322769 METHODS OF REDUCING VIRULENCE IN BACTERIA  
A method of reducing virulence in a bacterium comprising at least one of a GacS/GacA-type system, a HrpX/HrpY-type system, a T3SS-type system, and a Rsm-type system, the method comprising...
US20140051879 BIODEGRADABLE PHOSPHOESTER POLYAMINES  
Novel biodegradable phosphoester polyamines are disclosed. The biodegradable phosphoester polyamines may be utilized as cross-linkers for sprayable compositions which may be used as tissue...