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US20080311667 Exogenous Markers for Oxidative Stress  
The invention provides oxogenous markers, designed and synthesized for the measurement and characterization of oxidative/nitrosative stress levels, thus enable the identification of the type of...
US20110287436 Detection Of Analytes And Nucleic Acids  
Methods of detecting at least one analyte and at least one nucleic acid in a sample are provided. Reagents for carrying out the methods are also provided.
US20150141390 PLANT STEROIDS AND USES THEREOF  
The invention relates to a drug conjugate including a drug and a plant steroid. The drug conjugate may target the drug for intestinal cell delivery, and thus may be used to treat diseases,...
US20150086615 STEROL DERIVATIVES AND USE THEREOF FOR TREATING DISEASES INVOLVING TRANSFORMED ASTROCYTE CELLS OR FOR TREATING MALIGNANT HAEMOPATHIES  
Novel sterol derivatives, the preparation method thereof, pharmaceutical compositions containing them and use thereof for treating diseases involving transformed astrocyte cells or for treating...
US20140056834 COSMETIC COMPOSITION COMPRISING CHRYSOPHANOL AS ACTIVE INGREDIENT FOR SKIN WHITENING  
A novel use of chrysophanol for skin whitening is provided, in which chrysophanol is included in a cosmetic composition as an effective ingredient for skin whitening. The chrysophanol compound has...
US20110136773 Pharmaceutical Uses of Lanosta-8,24-dien-3-ols  
The invention generally refers to pharmaceutical uses of lanosta-8,24-dien-3-ols, a family of tetracyclic terpenols, as anti-inflammatory, anticancerigenous and analgesic agents via the inhibition...
US20130274489 METHOD FOR OBTAINING PHYTOSTEROLS AND/OR TOCOPHEROLS FROM RESIDUE OF A DISTILLATION OF THE ESTERS OF VEGETABLE OILS, PREFERABLY FROM DISTILLATION RESIDUE FROM A TRANSESTERIFICATION OF VEGETABLE OILS  
The invention relates to a method for obtaining and purifying phytosterols and/or tocopherols from distillation residue from a transesterification of vegetable oils, in particular from the...
US20100004473 METHOD FOR PRODUCING COENZYME Q10 PARTICLE  
The present invention aims to provide a production method capable of industrially and producing coenzyme Q10 particles having a high content and superior powder flowability characteristics by...
US20100004211 7-N-Substituted Phenyl Tetracycline Compounds  
7-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described.
US20130190280 Anti-Diabetic Compounds  
The preset invention relates to a new oral anti-diabetic compound prepared by synthesizing a steroid and a guanide or biguanide, which is eliminated via the hepatic route, instead of the renal...
US20080187947 Cholesterol-Mimetic Pyrene Probes  
The invention concerns compounds called pyrene-cholesterols, of general formula (I), wherein: X represents a CH2 group or an oxygen atom and n is an integer from 2 to 10, as well as their use for...
US20090281340 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND TREATMENT THEREOF  
Disclosed are 1α-hydroxy-2-(3′-hydroxypropylidene)-19-nor-vitamin D compounds, pharmaceutical compositions, and methods of making and treatment thereof. The compounds are generally directed to...
US20090062243 Lupane-Type Triterpenoids Modified at 30-Position and Analogues Thereof  
The present invention comprises lupine-type triterpenoids that inhibit cell proliferations, in particular cancer and conditions associated with cancer. For example, associated malignancies include...
US20110245501 Substituted Tetracycline Compounds as Synergistic Antifungal Agents  
The present invention relates to substituted tetracycline compounds and related methods for increasing the antifungal activity of an antifungal agent. The methods include administering to a...
US20090298800 1,25-DIHYDROXY, 20-CYCLOPROPYL,26-27-DEUTEROALKYL VITAMIN D3 COMPOUNDS AND METHODS OF USE THEREOF  
The invention provides vitamin D3 analogs of cholecalciferol, substituted at carbons-26 and 27 with deuterated alkyl groups, e.g., trideuteromethyl, wherein carbon-16 is a single or double bond,...
US20130217902 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR INHIBITING MAMMALIAN TUMOR CELL PROLIFERATION  
Compounds of following general formula (I) and pharmaceutical compositions thereof for inhibiting mammalian tumor cell proliferation are disclosed. In formula (I), n is an integer from 0 to 9. The...
US20110274743 Medicament for the Treatment of Pain and Inflammation  
The use of vitamin D3 for the manufacture of a medicament for the transdermal treatment of neurogenic inflammation and neuropathic pain (including peripheral neuropathic pain); also a method for...
US20060089340 Novel steroids and steroid mimetics; method for their production; and use thereof  
The invention relates to the production and use of novel 14β-alkyl-18-norsteroids, 8α,14β-dialkyl-18-norsteroids, spiro[cyclopentano-perhydronaphthalin]-3,1′-pentanes or hexanes in addition to...
US20090170822 2-Methylene-20-Methyl-19,24,25,26,27-Pentanor-Vitamin D Analogs  
This invention discloses 2-methylene-20-methyl-19,24,25,26,27-pentanor-vitamin D analogs, and specifically 2-methylene-20-methyl-1α-hydroxy-19,24,25,26,27-pentanor-vit amin D3, and pharmaceutical...
US20140309398 OLIGOMER-CORTICOSTEROID CONJUGATES  
The invention provides corticosteroids that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of...
US20080220069 Long Acting Injectable Crystal Formulations of Estradiol Metabolites and Methods of Using Same  
The present invention provides sustained release formulations of estradiol metabolites whereby the in vivo pharmacokinetics are manipulated by a method selected from the group consisting of...
US20120195988 Therapeutic Uses for Plants of the Capsicum Genus  
A saponin or a sapogenin, or a saponin or sapogenin derivative, from a plant of the capsicum genus for use in the treatment of a disease other than eczema and dermatitis. A process for preparing a...
US20090197844 Demethylpenclomedine Analogs and Their Use as Anti-Cancer Agents  
This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders. In one...
US20120107255 PHOTOSTABILIZATION OF CHOLECALCIFEROL WITH ALKOXYCRYLENE COMPOUNDS  
A method of reducing photodegradation of cholecalciferol when exposed to UV radiation in a composition containing cholecalciferol comprising combining with cholecalciferol a compound of formula...
US20120157419 METHODS AND COMPOSITIONS FOR TREATING ALZHEIMER'S DISEASE  
The present invention relates to methods for treatment, prevention, and inhibition of progression of Alzheimer's disease, and other brain diseases characterized by amyloid plaque deposits,...
US20140329780 INHIBITOR OF COLONISATION OF MUCOSA  
The present invention relates in the first aspect to the use of aurintricarboxylic acids, derivatives, oligo- or polymers or salts, for inhibiting adherence and colonisation of microorganisms,...
US20130316995 FATTY ACID CONJUGATES OF STATIN AND FXR AGONISTS; COMPOSITIONS AND METHOD OF USES  
The invention relates to fatty acid statin conjugates and fatty acid FXR agonist conjugates; compositions comprising an effective amount of a fatty acid statin conjugate or a fatty acid FXR...
US20090156842 Methods for synthesizing substituted tetracycline compounds  
Methods of synthesizing substituted tetracycline compounds are provided.
US20130178450 METHODS FOR INCREASING THE PRODUCTION OR ACTIVITY OF CATALASE  
Methods and compositions for increasing the production or activity of catalase in an animal are disclosed. The methods comprise administering vitamin D to the animal in an amount effective to...
US20140378529 COLLATERAL GENE INACTIVATION BIOMARKERS AND TARGETS FOR CANCER THERAPY  
Methods for treating a subject determined to have a cancer comprising a heterozygous inactivation of a housekeeping gene (or a homozygous deletion of a functionally redundant housekeeping gene) by...
US20140121189 USE OF 3-ALPHA-ANDROSTANEDIOL, OPTIONALLY IN COMBINATION WITH A 5-HT1A AGONIST, IN THE TREATMENT OF SEXUAL DYSFUNCTION  
The invention relates to the field of male and/or female sexual dysfunction. The invention specifically relates to the use of 3-alpha-androstanediol, preferably in combination with a 5-HT1A...
US20110144347 PROCESS FOR THE EPIMERIZATION OF ATOVAQUONE ISOMER, ATOVAQUONE INTERMEDIATES AND MIXTURE THEREOF  
Provided is a process for the epimerization of the cis isomer of atovaquone, atovaquone intermediates and isomeric mixtures thereof into their corresponding trans-isomers resulting in higher yield...
US20110118225 Ligands of Estrogen Receptors alpha and beta, Method of Their Preparation, and Pharmaceuticals Comprising Them  
The invention relates to novel ligands of the estrogen receptors α and β of general formula II, which are useful as an active substance of pharmaceuticals, for example pharmaceutical compositions...
US20080015367 PROCESS FOR ISOLATING PHYTOSTEROLS AND TOCOPHEROLS FROM DEODORIZER DISTILLATE  
A process is described for efficiently recovering at least one of phytosterols and tocopherols in substantially pure form from the deodorizer distillates that may be obtained as by-products of the...
US20100286106 METHODS AND APPARATUS FOR TREATING THE PROSTATE  
Treating and/or preventing prostate problems and/or metastases, by selectively occluding various groin vessels and tools for selective occluding of various groin veins, including, for example, the...
US20110263546 Polyhydroxylated Bile Acids for Treatment of Biliary Disorders  
The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis or portal hypertension. The invention also...
US20060166951 Compositions and methods for sterol isolation and purification  
Compositions and methods for isolating and purifying sterols, stanols, policosanols, and other organic molecules of interest are disclosed. The compositions encompass purified sterols comprising,...
US20130165421 4-[17BETA-METHOXY-17ALPHA-METHOXYMETHYL-3-OXOESTRA-4,9-DIEN-11-BETA-YL]BENZALDEHYDE (E)-OXIME (ASOPRISNIL)  
The present invention relates to a method for the reliable and reproducible preparation of 4-[17β-methoxy-17α-methoxymethyl-3-oxoestra-4,9-dien-11β-yl] benzaldehyde (E)-oxime (asoprisnil) on the...
US20140349866 NEW TH-17 DIFFERENTIATION MARKERS FOR ROSACEA AND USES THEREOF  
Methods are described for using genes crucial in TH17 differentiation, IL-12Rbeta 1/IL-23R, CCR6, BATF, AHR, STAT3 and IRF4 as new markers for rosacea. Also described, are methods of their use to...
US20110301363 METHOD FOR CARRYING OUT OXIDATION REACTIONS USING INDUCTIVELY HEATED HEATING MEDIUM  
The invention relates to a method for carrying out an oxidation reaction for producing a product by heating a reaction medium containing a reactant and oxygen or an oxygen carrier in a reactor,...
US20120258184 HYPERLIPEMIA-AMELIORATING AGENT, ANEMIA-AMELIORATING COMPOSITION, URIC-ACID-LEVEL-REDUCING COMPOSITION, AND FOOD OR BEVERAGE  
A neutral-fat-level-regulating agent, a cholesterol-level-regulating agent, a free-fatty-acid-level-regulating agent or an anti-obesity agent, including: at least one of protopanaxatriol,...
US20140113886 Stabilized 1, 25-Dihydroxyvitamin D2 and Method of Making Same  
A stabilized 1,25-dihydroxyvitamin D2 composition which is particularly well suited for pharmaceutical formulations, pharmaceutical formulations of the 1,25-dihydroxyvitamin D2 composition, and a...
US20060093571 Hair and skin protecting compositions based on esters or ethers of betulin  
Personal care compositions and formulations, which include conventional concentrations of known hair and skin altering components and a cosmetically acceptable amount of oil-soluble betulin and...
US20090131698 Method For Obtaining Conjugated Estrogen Mixtures From Pregnant Mare Urine and Use of a Macroporus Resin in the Method  
The present invention relates to a method for obtaining a natural mixture of conjugated estrogens from urine of pragnant mares (PMU) and use of a macroporous adsorption resin in the method. The...
US20120059179 PALLADIUM-CATALYZED ORTHO-FLUORINATION  
A new method of ortho-fluorination where an aryl C—H bond is directly replaced by an aryl C-F bond in a palladium-catalyzed reaction is provided. The method includes the ortho-fluorination of a...
US20150045329 SUBSTITUTED TETRACYCLINE COMPOUNDS  
The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states,...
US20110009371 SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF  
The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary...
US20070225310 Antiviral methods and compositions  
Disclosed herein are antiviral compounds, such as anti-human cytomegalovirus antiviral compounds, pharmaceutical compositions and antiviral methods.
US20060057101 German cockroach attractant  
A compound of the formula I where R represents unsubstituted or substituted, alkyl, cycloalkyl, alkenyl, alkynyl, or aryl, and X represents where R1 and R2 are each H or alkyl, is disclosed....
US20060189576 Substituted vitamin d analogues and their therapeutic uses  
The present invention relates to analogues of vitamin D namely 14-epi-2-alkyl-19-nor vitamin D derivatives. Also a general method for the synthesis and the biological activities are described. The...