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US20120071453 STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM  
A compound with general formula I for treatment of various diseases of the central nervous system, in treatment of neuropsychiatric disorders related to imbalance of glutamatergic neurotransmitter...
US20140287051 ORALLY ADMINISTERED CORTICOSTEROID COMPOSITIONS  
The present invention is directed to orally administered corticosteroid compositions. The present invention also provides a method for treating a condition associated with inflammation of the...
US20110081411 Orally Administered Corticosteroid Compositions  
The present invention is directed to orally administered corticosteroid compositions. The present invention also provides a method for treating a condition associated with inflammation of the...
US20150141385 Methods Useful for Vitamin D Deficiency and Related Disorders  
Methods for diagnosing, treating, and preventing catabolism-related vitamin D deficiency and related disorders, related compositions, apparatus and kits, are disclosed. A method involves measuring...
US20140221658 INHIBITION OF CELL PROLIFERATION  
The disclosed modulators of Rb:Raf-1 interactions are potent, selective disruptors of Rb:Raf-1 binding, with IC50 values ranging from 80 nM to 500 nM. Further, these compounds are surprisingly...
US20140045806 SEXUAL AROUSAL, SEXUAL DESIRE, ORGASM AND/OR PLEASURE FOLLOWING INTRAVAGINAL PRASTERONE (DHEA) ADMINISTRATION IN WOMEN NOT SUFFERING OR INDEPENDENTLY FROM DYSPAREUNIA OR OTHER SYMPTOMS OF VULVO-VAGINAL ATROPHY  
Intravaginal DHEA is used for the treatment of at least one condition selected from the group consisting of female hypoactive sexual desire disorder, female sexual arousal disorder, female orgasm...
US20150239927 CRYSTALLINE POLYMORPHIC FORM OF ULIPRISTAL ACETATE  
A novel crystalline polymorphic form of ulipristal acetate useful as an agent for preventing and/or treating uterine leiomyoma and as a contraceptive, and a process for producing the crystalline...
US20150203526 NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS  
The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. New compounds and methods for treating these conditions are disclosed....
US20130274234 NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS  
The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. New compounds and methods for treating these conditions are disclosed....
US20150079165 Treating vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3  
Methods and compositions for treating 25-hydroxyvitamin D insufficiency and deficiency in a patient are described herein. The method includes orally administering to the patient a delayed,...
US20110207951 7-Iodo Tetracyclines and Related Methods  
7-substituted fused ring tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted fused ring tetracycline compounds...
US20110144072 Antiglucocorticoid Therapy for the Prevention of Neurological Damage in Premature Infants  
This invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for preventing neurological damage associated with glucocorticoid...
US20150094291 Method and Substance for Improving the Emotional Development of an Infant  
The invention provides a method for improving the emotional development of an infant by performing controlled exposure of the infant aged less than six months old to human fear pheromone,...
US20150166470 7-DISUBSTITUTED-PHENYL TETRACYCLINE DERIVATIVES  
7-Disubstituted-phenyl tetracycline compounds are disclosed herein. Also disclosed is a method for treatment or prevention of spinal muscular atrophy using the 7-disubstituted-phenyl tetracycline...
US20120083614 (20R,25S)-2-Methylene-19,26-Dinor-1alpha,25-Dihydroxyvitamin D3 in Crystalline Form  
A method of purifying (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin D3 to obtain (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin D3 in crystalline form. The method includes the...
US20140045808 Reducing Risk of Contracting Clostridium-Difficile Associated Disease  
A method of treating a patient to reduce risk of developing Clostridium difficile-associated disease or reducing existing Clostridium difficile-associated disease in a mammalian subject involves...
US20150232392 METHOD FOR SYNTHESIZING RADIOPHARMACEUTICALS USING A CARTRIDGE  
The present invention relates to a method for synthesizing a radiopharmaceutical using a cartridge, which makes it possible to carry out several steps of reaction required for synthesizing a...
US20090136434 Tyrosinase enzyme inhibitors from fungal hydroxylation of tibolone  
Seven new and one known metabolites of tibolone were obtained by incubation of tibolone with various fungi. Their structures were elucidated by means of a homo and heteronuclear 2D NMR and by...
US20150099871 LENTINAN EXTRACTION PROCESS FROM MUSHROOMS USING IONIC LIQUID  
A method of extracting lentinan from lentinan containing mushrooms comprising the step of contacting the mushrooms with an ionic liquid so as to obtain a lentinan rich ionic liquid solution.
US20130225542 Therapeutic Gestagens For The Treatment Of Premenstrual Dysphoric Disorder  
This invention describes the use of a therapeutic gestagen (e.g., drospirenone, cyproterone acetate, dienogest) for the production of a pharmaceutical agent for the treatment of premenstrual...
US20130039952 CALCIPOTRIOL MONOHYDRATE NANOCRYSTALS  
Calcipotriol monohydrate nanocrystals prepared by the process disclosed herein may be incorporated in a pharmaceutical composition for use in the prevention or treatment of dermal diseases and...
US20130338118 COMPOUNDS FOR TREATMENT OF HEART FAILURE  
A combination of: a first tetracycline (TC) component; and a second component capable of releasing nitric oxide (NO) or a nitrate capable of mimicking NO effects in vivo (NO mimetic). The...
US20110262970 Enzymatic Hydrolysis Of Pretreated Lignocellulose-Containing Material With Cationic Polysaccharides  
A method for producing a fermentation product from a lignocellulose-containing material comprises pre-treating the lignocellulose-containing material; introducing a cationic polysaccharide to the...
US20070161779 Estrogen Extraction From Pregnant Animal Urine  
A method of extracting oestrogens, conjugated estrogens, equine gonadotropin and equine follicle stimulant from pregnant mares urine which includes the steps of contacting the urine with dispersed...
US20060135491 Vitamin D3 analog useful for the treatment of osteoporosis  
The present invention relates to the vitamin D3 analog (1R,3R)-5-{(E)-(2R, 5R)-2-[2-(4-hydroxy-4-methylpentyl)-spiro[4.5]dec-7-ylidene] -ethylidene}-cyclohexane-1,3-diol which is useful in the...
US20140179761 TARGETING LIPIDS  
The present invention provides targeting lipids of structure L100-linker-L101 (CI), where L100 is a lipid, lipophile, alkyl, alkenyl or alkynyl, L101 is a ligand or...
US20140271673 USE OF LXR ANTAGONISTS FOR TREATMENT OF SIDE EFFECTS OF ELEVATED GLUCOCORTICOID LEVELS  
The present application is directed to uses of an agent that antagonizes the LXRβ receptor for the treatment of side effects associated with elevated glucocorticoid levels as well as uses of a...
US20110018866 STRUCTURE OF THE FARNESOID X RECEPTOR LIGAND BINDING DOMAIN AND METHODS OF USE THEREFOR  
The present invention provides compositions comprising the ligand binding domain (LBD) of a farnesoid X receptor (FXR) in crystalline form. In alternative embodiments, the LBD of FXR is complexed...
US20140248707 RELEASE REAGENT FOR VITAMIN D COMPOUNDS  
A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein and an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is...
US20120203102 AZULENE AND AZAAZULENE SYSTEMS FOR IMAGING, MONITORING AND THERAPY  
This invention is directed to non-benzenoid aromatic compounds. Other aspects include methods of using non-benzenoid aromatic compounds for imaging and phototherapeutic uses thereof. Non-benzenoid...
US20140154700 Compositions and Methods for Detecting Vitamin D  
Compounds include carbamate derivatives of vitamin D including vitamin D3 and vitamin D2. The compounds are useful in methods and kits for determining the presence and/or amount of vitamin D...
US20130338116 COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES  
The present invention relates generally to pharmaceutical agents, and in particular, to metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of dual...
US20110230452 Compounds and methods for the treatment of pain and other diseases  
The present invention relates generally to pharmaceutical agents, and in particular, to metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of dual...
US20120142786 OREGANO EXTRACT FOR ALERTNESS  
Oregano extract can act as a stimulant, yet it does not interfere with sleep patterns or induce nervousness the way many stimulants such as caffeine can. It also has the benefits of promoting...
US20110244060 CARDIOPROTECTIVE EFFECTS OF NUTRACEUTICALS ISOLATED FROM NIGELLA SATIVA SEEDS  
This invention relates to a rich antioxidant nutraceuticals prepared from Nigella sativa seeds for the treatment and prevention of hypercholesterolemia. These nutraceuticals when taken enterally...
US20110059926 Vitamin D Compounds and Methods for Reducing Ocular Hypertension (OHT)  
The present invention relates to compounds and methods for reducing intraocular pressure and treating ocular hypertension in a subject.
US20090318395 3-HYDROXYCHLORMADINONE ACETATE FOR THE TOPICAL TREATMENT OF ANDROGEN-DEPENDENT SKIN DISEASES  
The present invention relates to the use of 3β-hydroxychlormadinone acetate (17α-acetoxychloropregna-4,6-dien-3β-ol-20-one) and/or 3α-hydroxychlormadinone acetate...
US20110217331 Inactivation of Reverse Transcriptases By Azido-diarylpyrimidines  
Azido-diarylpyrimidine (azido-DAPY) compounds, and compositions containing such compounds, are provided. In addition, methods of using azido-diarylpyrimidines to inactivate reverse transcriptases,...
US20130295083 2a-Methyl-19-nor-(20S)-1a,25-dihydroxyvitamin D3 (2AMD) or 2 methylene-19-nor-(20S)-1a,25-dihydroxyvitamin D3 (2MD) Support Survival and Function of Transplanted Islet Cells In Type 1 Diabetes  
A method of treating islet cell transplant patients is described herein. The method comprises the steps of a) identifying an islet cell transplant patient, b) treating the patient with 2AMD or...
US20150118277 OXYSTEROL ANALOGUE OXY133 INDUCES OSTEOGENESIS AND HEDGEHOG SIGNALING AND INHIBITS ADIPOGENESIS  
This invention relates, e.g., to a synthetic compound, Oxy133, having the structure [Formula I] or a bioactive or pharmaceutical composition comprising Oxy133 and a pharmaceutically acceptable...
US20110195942 METHOD OF MAKING AND USING 7ALPHA, 11BETA-DIMETHYL-17BETA-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE  
Methods of using 7α,11β-dimethyl-17β-hydroxy-4-estren-3 -one bucyclate (I) and 7α,11β-dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate (II) for various hormonal therapies, dosage forms...
US20130090486 Crystallization of 1alpha-Hydroxy-2-Methylene-18,19-Dinor-Homopregnacalciferol  
A method of purifying 1α-hydroxy-2-methylene-18,19-dinor-homopregnacalciferol to obtain 1α-hydroxy-2-methylene-18,19-dinor-homopregnacalciferol in crystalline form using precipitation with hexane...
US20110177156 Sterol-Modified Amphiphilic Lipids  
Disclosed are sterol-modified amphiphilic lipid compounds having two or more hydrophobic tails of which at least one is a sterol. Also disclosed are the processes for the synthesis of these...
US20150239928 CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS  
Disclosed herein are cationic steroidal antimicrobials (“CSAs” or “ceragenins”) and methods of making the same. Particularly advantageous methods are identified for the synthesis of CSAs. CSAs may...
US20120244627 Methods for Quantifying Vitamin D Metabolites by Mass Spectrometry  
Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise associating an amine with a...
US20110073810 PROCESS FOR PREPARING ISOTOPICALLY LABELED VITAMINS SUITABLE FOR USE AS ANALYTICAL REFERENCE STANDARDS  
The present invention is directed to a method for the synthesis of deuterium labeled Vitamin D and related compounds with a high level of deuterium incorporation, which are particularly suitable...
US20110158947 SULFONYLUREA RECEPTOR AND MEANS FOR TREATING ISCHAEMIA  
We disclose agents useful in the treatment of diseases or conditions that would benefit from improved muscle function and including pharmaceutical compositions and diagnostic tests for determining...
US20150005518 PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS  
A process ethynylates 16-methylene-17-keto steroids to the corresponding 16-methylene-17α-ethynyl-17β-hydroxy steroids by treatment with silyl-protected lithium acetylides followed by further...
US20120253032 NOVEL CATIONIC LIPIDS WITH SHORT LIPID CHAINS FOR OLIGONUCLEOTIDE DELIVERY  
The instant invention provides for novel cationic lipids with short lipid chains that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid...
US20120295985 METHODS FOR IMPROVING BLOOD GLUCOSE CONTROL  
The present invention is concerned with a method for improving blood glucose control or for preventing or treating a condition requiring increasing insulin sensitivity or reducing insulin...