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US20120183468 Water-Soluble Functionalized Fullerenes  
Provided herein are water-soluble, functionalized fullerenes, and processes for producing water-soluble, functionalized fullerenes. The process includes sulfonating a fullerene in an acidic...
US20130137884 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID  
Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for...
US20090131389 Preparation of a Crystalline Antibiotic Substance  
The present invention relates to processes for the crystallisation and for the preparation and isolation of a novel crystalline form of fusidic acid, to the use of said processes in the...
US20120058977 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS  
A pharmaceutical composition for the treatment of a disease caused by a bacterium that belongs to the group of nocardioform actinomycetes, said composition comprising an effective amount of a...
US20090318722 PROCESS FOR PREPARATION OF PARICALCITOL INTERMEDIATES  
The present invention relates to a compound and a novel process for the preparation of Paricalcitol intermediates.
US20090326251 METHODS FOR PREPARING 17-ALKYNYL-7-HYDROXY STEROIDS AND RELATED COMPOUNDS  
The invention relates to processes for preparing 17-alkynyl-7-hydroxy-steroids, such as 17-Ethynyl-10R,13S-dimethyl 2,3,4,7,8R,9S,...
US20140348900 METHODS AND DEVICES FOR PREPARATION OF LIPID NANOPARTICLES  
The present invention provides for a process for preparing liposomes, lipid discs, and other lipid nanoparticles using a multi-port manifold, wherein the lipid solution stream, containing an...
US20050192263 Novel 17beta-hydroxysteroid dehydrogenase type I inhibitors  
3,15-substituted estrone compounds which act as inhibitors of 17β-hydroxysteroid dehydrogenase type I (17β-HSD1), salts thereof, pharmaceutical preparations containing such compounds, processes...
US20070025976 Process for the purification of coenzyme Q10  
The present invention relates to methods for purifying Coenzyme Q10.
US20090306031 5alpha-ANDROSTANE-3,6,17-TRIONE (KNELLER'S TRIONE) AND METHODS OF USE THEREFOR  
Disclosed are compounds such as 5α-androstane-3,6,17-trione, formulations comprising said compounds, and methods of use thereof to stimulate endogenous testosterone production and improve athletic...
US20150140063 HYDROPHOBIC CERAGENIN COMPOUNDS AND DEVICES INCORPORATING SAME  
A hydrophobic cationic steroidal anti-microbial (ceragenin) compound forms an amphiphilic compound having a hydrophobic sterol face and a hydrophilic cationic face. The hydrophobic CSA also...
US20120035328 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES  
Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence...
US20130072698 Method and Compounds for the Preparation of Monofluoromethylated Biologically Active Organic Compounds  
Described are processes for the preparation of monofluoromethylated organic biologically active compounds, such as Fluticasone Propionate and Fluticasone Furoate, in the presence of...
US20070225264 Drug delivery means  
The invention broadly comprises a chemical composition including a plurality of cholesteryl esters arranged to form a vesicle. In several embodiments, all of the plurality of cholesteryl esters...
US20050165044 Fused ring dicationic anti-protozoan agents and their prodrugs  
Novel fused ring dicationic anti-protozoan compounds. Representative protozoan species include but are not limited to Trypanosoma brucei rhodesiense (T.b.r.) and Plasmodium falciparum. Prodrugs of...
US20130004836 ELECTRODE ACTIVE MATERIAL FOR ELECTRICITY STORAGE DEVICE, AND ELECTRICITY STORAGE DEVICE USING SAME  
The present invention provides an electrode active material for an electricity storage device, having a structure represented by following formula (1). In the formula (1), R1 to R6 each denote...
US20100160656 7-PHENYL-SUBSTITUTED TETRACYCLINE COMPOUNDS  
7-phenyl-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the...
US20130018180 CRYSTALS OF HUMAN TOPOISOMERASE II-DNA BINARY COMPLEX, METHODS FOR PREPARING THE SAME AND USES THEREOF  
Disclosed herein are a crystal of a human TOPII (hTOPII)-DNA binary complex, the method for preparing the same and the use thereof. The hTOPII-DNA binary complex includes an hTOPII portion that...
US20140011778 2-METHYLENE-19,23,24-TRINOR-1ALPHA-HYDROXYVITAMIN D3  
Compounds of Formula I are provided where R1 and R2 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are...
US20130053356 2-METHYLENE-19,23,24-TRINOR-1ALPHA-HYDROXYVITAMIN D3  
Compounds of Formula I are provided where R1 and R2 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are...
US20080194534 Modified Retinoid Compounds and Their Uses  
A method of minimizing or reducing the toxicity of a retinoid having a free carboxyl group and the resulting modified retinoids are described. The method comprises the step of esterifying the...
US20070135394 Process for the synthesis of vitamin d compounds and intermediates for the synthesis of the compounds  
An object of the present invention is to provide a process for synthesizing a vitamin D compound by simple procedures at lower costs. The present invention provides a process for preparing a...
US20120277448 PREPARATION METHOD FOR 3BETA-ARACHIDYLAMIDO-7ALPHA, 12ALPHA, 5BETA-CHOLAN-24-CARBOXYLIC ACID  
A method for preparing 3β-arachidylamido-7α,12α,5β-cholan-24-carboxylic acid represented by the following formula V is disclosed, which includes the following steps: converting cholic acid to the...
US20110112293 Purification Strategy for Direct Nucleophilic Procedures  
The present invention provides novel and advantageous processes for preparing and purifying chemical compounds such as pharmaceuticals. The processes comprise a nucleophilic substitution reaction...
US20120142644 METHOD FOR PRODUCING PHYTOSTEROL/PHYTOSTANOL PHOSPHOLIPID ESTERS  
The present invention relates to a method of producing a phytosterol ester and/or a phytostanol ester comprising: a) admixing a phospholipid composition comprising at least between about 10% to...
US20130053507 HYDROPHOBIC CERAGENIN COMPOUNDS AND DEVICES INCORPORATING SAME  
A hydrophobic cationic steroidal anti-microbial (ceragenin) compound forms an amphiphilic compound having a hydrophobic sterol face and a hydrophilic cationic face. The hydrophobic CSA also...
US20090169484 IRON-SALEN COMPLEX  
The present invention provides a drug delivery system that overcomes conventional technical problems and that is readily put to practical use. Iron-salen complexes represented by General Formula...
US20110172198 TGR5 Modulators And Methods Of Use Thereof  
The invention relates to compounds of Formula A: (A) or a salt, solvate, or hydrate thereof. The compounds of formula A are TGR5 modulators useful for the treatment of disease.
US20130210785 PROGESTERONE ANALOGS AND USES RELATED THERETO  
This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation...
US20100273725 Novel compounds useful in therapeutic and cosmetic methods  
The present invention relates to photosensitizer compounds for use in cosmetic and therapeutic applications of photodynamic therapy. The compounds of the present invention are designed for topical...
US20060211873 Synthesis of cyproterone acetate  
The present invention relates to improved methods for synthesising cyproterone acetate (17α-Acetoxy-6-chloro-1α, 2(α-methylene-4,6-pregnadiene-3,20-dione) from solasodine.
US20060246509 Unnatural reactive amino acid genetic code additions  
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include...
US20140142329 Catalyst Support and Process for the Preparation Thereof  
An amorphous catalyst support comprising at least a first oxide selected from the group consisting of: silica, germanium oxide, titanium oxide, zirconium oxide or mixtures thereof, preferably...
US20120123138 Catalyst support and process for the preparation thereof  
An amorphous catalyst support comprising at least a first oxide selected from the group consisting of: silica, germanium oxide, titanium oxide, zirconium oxide or mixtures thereof, preferably...
US20070225261 Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers  
Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis,...
US20100160276 SYNTHETIC BILE ACID COMPOSITIONS AND METHODS  
Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin...
US20070123500 Prodrugs of ERbeta-selective substances, processes for their preparation and pharmaceutical compositions comprising these compounds  
The present invention makes available prodrugs of 9α-substituted oestratrienes of the general formula (I) in which the group Z is bonded to the steroid, processes for their preparation,...
US20120082715 Stabilized products, processes and devices for preparing the same  
A composition comprising a glassified, stabilized particle preparation having a low water activity (between about 0.1 and 0.9) is provided. The preparations provide improved products with enhanced...
US20110184198 New Process for Isomerizing Fused Bicyclic Structures and Preparation of Vitamin D Analogs Comprising the Same  
The present invention concerns a process of isomerizing trans fused bicyclic derivatives into cis fused bicyclic derivatives and the preparation of vitamin D or analogs thereof comprising said...
US20100292183 TETRACYCLINE AND USES THEREOF  
Provided herein are methods and compositions for the in vitro formation of tetracycline conjugates, for example, tetracycline conjugated to anti-coagulants. The present invention also provides...
US20150018436 LIPOPOLYAMINES OF SPERMINE TYPE FOR CONSTRUCTION OF LIPOSOMAL TRANSFECTION SYSTEMS  
The invention provides new lipopolyamines of spermine type of the general formula I, wherein X is C—N bond or aminopolyethyleneglycolcarboxamide linker or o-hydroxy-alkylcarboxamide linker or...
US20130296588 Anthraquinone Compounds and Their Uses  
The present invention relates to a compound comprising a substituted or unsubstituted anthraquinone, or a salt or isomer thereof, for use in treating a disorder caused by or associated with...
US20070048252 Conjugates of the hydrophilic polymer and the molecules from boxwood extraction, and pharmaceutical compositions of the conjugates  
The present invention relates to a group of conjugates of the hydrophilic polymers and the molecules from boxwood extraction. PEGylation process or the process alike was used to generate the...
US20090312293 PROCESS FOR THE ISOLATION OF PHARMACOLOGICALLY ACTIVE PRINCIPLES OF VEGETABLE AND ANIMAL ORIGIN  
A process for the recovery and purification of natural hydrophilic water-soluble products in conjugated form from vegetable aqueous extracts or physiological fluids, by adsorption of the extracts...
US20090062558 Process for preparing Estrogen-antagonistic 11 beta-Fluoro-17alpha-alkylestra-1,3,5(10)-triene-3,17-diols having a 7alpha-(xi-Alkylamino-omega-perfluoroalkyl)alkyl side chain and alpha-Alkyl(amino)-omega-perfluoro(alkyl)alkanes and Processes for their Preparation  
The present invention relates to a new process for preparing estrogen-antagonistic 11β-fluoro-17α-alkylestra-1,3,5(10)-triene-3,17-diols of the general formula I having a...
US20090226431 Treatment of Cancer and Other Diseases  
The present invention relates to a novel compound (e.g., 24-ethyl-cholestane-3β,5α,6α-triol), its production, its use, and to methods of treating neoplasms and other tumors as well as other...
US20100249076 PRODRUGS OF 9-AMINOMETHYL TETRACYCLINE COMPOUNDS  
The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them.
US20130210787 C-3 CYCLOALKENYL TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY  
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-3 cycloalkenyl triterpenoids that possess unique antiviral...
US20070066566 19,23,24,25,26,27-Hexanor-1alpha-hydroxyvitamin D3  
A compound or composition is provided that comprises a compound of formula 1A, where, X1 and X2 are independently selected from H or hydroxy-protecting groups. Also provided are compounds that...
US20090148542 Composition comprising an extract of tiarella polyphylla and tiarellic acid isolated therefrom having antiinflammatory, antiallergic and antiasthmatic activity  
The present invention relates to a composition comprising an extract of Tiarella polyphylla, and tiarellic acid isolated therefrom having anti-inflammatory, anti-allergic and anti-asthmatic...