Match Document Document Title
US20090270642 Preparation of bile acids and intermediates thereof  
Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
US20080318911 20-Cyclopropyl, 26,27-Alkyl/Haloalkyl Vitamin D3 Compounds and Methods of Use Thereof  
The invention provides vitamin D3 analogs of cholecalciferol, substituted at carbon 20 with cycloalkyl, e.g., cyclopropyl, wherein carbon-16 is a double bond, and carbon-23 is a single, double, or...
US20110130581 Method and intermediates for preparing 2-alkoxy and 2-aryloxy estrogen compounds  
The present invention relates to 2-alkoxy and 2-aryloxyestrogen compounds, and the intermediate compounds prepared during the preparation thereof, which intermediate compounds are useful...
US20110230670 AZIDE COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF  
Azide compositions selected from i) UOCR2CR2N3 wherein U is D, or a urethane (—CO—NR2) and R is independently H, D, or an organic group; ii) R′2NCR2CR2N3 or A-R′3NCR2CR2N3 wherein R′ is an organic...
US20060247452 Method for obtaining 17sg(a)-acetoxy-11$g(b)-(4-n,n-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione  
The process comprises (a) forming 17α-acetoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9 -diene-3,20-dione (VA-2914) isopropanol hemisolvate crystals by dissolving in isopropanol and...
US20140141247 PROCESS FOR THE PREPARATION OF FLUTICASONE PROPIONATE FORM 1  
The invention relates to a novel crystallisation process for preparing fluticasone propionate as crystalline form 1 polymorph with controlled particle size and suitable for micronisation. Said...
US20100311708 USE OF NOR-BILE ACIDS IN THE TREATMENT OF ARTERIOSCLEROSIS  
The present invention relates to the use of nor-bile acids and their pharmaceutically acceptable salts, esters and/or derivatives in the treatment arteriosclerosis.
US20070219173 LIGANDS FOR NEMATODE NUCLEAR RECEPTORS AND USES THEREOF  
Anti-nematode compounds, compositions, and methods for identifying such compounds are disclosed, where the compounds have the formula I: where Q, Q′, R1, R2, and n are defined herein.
US20130150598 USE OF 25-HYDROXY-VITAMIN D3 TO AFFECT HUMAN MUSCLE PHYSIOLOGY  
The use of 25-OH D3 (calcifediol) to increase muscle strength, muscle function, or both is provided. Vitamin D3 (cholecalciferol) may optionally be used together with 25-OH D3. Forms and dosages...
US20110039810 USE OF 25-HYDROXY-VITAMIN D3 TO AFFECT HUMAN MUSCLE PHYSIOLOGY  
We disclose the use of 25-OH D3 (calcifediol) to increase muscle strength, muscle function, or both. Vitamin D3 (cholecalciferol) may optionally be used together with 25-OH D3. Forms and dosages...
US20090075964 FRAGRANCE COMPOSITIONS AND OTHER COMPOSITIONS WHICH CONTAIN NATURALLY OCCURRING SUBSTANCES FOUND IN CORALS  
This invention is generally related to the fields of fragrance compositions, personal care products, and home consumer products. This invention also relates to 20-pregnenes, in particular those...
US20130225845 PROCESS FOR PREPARATION OF ESTRADIOL VALERATE AND A NOVEL CRYSTALLINE FORM A OF ESTRADIOL DIVALERATE  
The present invention relates to the process for the preparation of estradiol valerate (I) which involves isolation of crystalline estradiol divalerate (III) by crystallization from an alcoholic...
US20150105547 NITRIC OXIDE RELEASING STEROIDS  
The invention relates to nitrooxyderivative of corticosteroids of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof R—(Z)a—Rx (I) wherein R is the corticosteroid...
US20150140605 ONE STEP N-TERMINAL TAGGING OF PROTEINS  
The invention includes a selective method of modifying the N-terminus of a protein using an aminoacyl tRNA transferase. In certain embodiments, the method comprises contacting a solution of the...
US20100036140 STEROLS MODIFIED BY POLYETHYLENE GLYCOL, THE PREPARATION AND THE USE THEREOF  
The invention provides sterols modified by polyethylene glycol represented by the following formula, the preparation and the use thereof, wherein each symbol is defined as in the description.
US20120277198 POLYHYDROXYLATED BILE ACIDS FOR TREATMENT OF BILIARY DISORDERS  
The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also...
US20100152150 THE APPLICATION OF MARINE STEROID IN PREPARING THE MEDICINE OF TREATING NEURONS DAMAGING  
The application of marine steroid, i.e. 24-methylene-cholest-3β,5α,6β,19-tetrol, in preparing the medicine of treating neurons damaging is provided in the present invention. The keto-sterols...
US20110270151 IMAGE-GUIDED ENERGY DEPOSITION FOR TARGETED DRUG DELIVERY  
Disclosed are compositions and methods for targeted drug delivery using image-guided energy deposition to help localize active compounds to particular sites within the body of an animal. Also...
US20110144071 CRYSTALLINE ACTIVE INGREDIENT MICROPARTICLES, METHOD FOR PRODUCING THE SAME AND USE THEREOF IN DRUGS  
A method for producing highly crystalline and stable microparticles of an active substance with a very narrow size distribution. The microparticles being crystallized out of a suspension made of...
US20090012321 PROCESS FOR PREPARING 17ALPHA-ACETOXY-6-METHYLENEPREGN-4-ENE-3,20-DIONE, MEDROXYPROGESTERONE ACETATE AND MEGESTROL ACETATE  
The present invention relates to a process for preparing 17α-acetoxy-6-methylenepregn-4-ene-3,20-dione (4) as an intermediate, and to processes for preparing medroxyprogesterone acetate (1)...
US20130217765 MULTIFUNCTIONAL NANOCONJUGATES AND USES THEREOF  
The present invention provides multifunctional nanoconjugates and methods of using them to destroy biological and chemical agents. The nanoconjugates include a dye-coated metal oxide nanoparticles...
US20080207931 Solid-Phase Extraction Method of Steroid Hormones by Entrapped Beta-Cyclodextrin Polymers  
Provided is a method for selective extraction of steroid compounds using entrapped β-cyclodextrin polymers. Particularly, steroid hormones can be effectively selected from a biological sample by...
US20130102574 2-METHYLENE-VITAMIN D ANALOGS AND THEIR USES  
This invention discloses 2-methylene-vitamin D analogs, and specifically (20S)-1α,25-dihydroxy-2-methylene-vitamin D3 as well as (5E)-(20S)-1α,25-dihydroxy-2-methylene-vitamin D3 and...
US20120115824 Vitamin D Receptor Agonists and Uses Thereof  
Disclosed is a compound of Formula (I) in which R1, R2, R3, R4, R5, R6, X, and a are defined herein, or a pharmaceutically acceptable salt thereof. Also disclosed are a pharmaceutical composition...
US20130324751 Crystallization of (20R) 19-Nor-24-Difluoro-1alpha,25-Dihydroxyvitamin D3  
Disclosed are methods of purifying the compound (20R)-19-nor-24-difluoro-1α,25-dihydroxyvitamin D3 to obtain the compound in crystalline form. The methods typically include the steps of dissolving...
US20140235824 Method to Wash Greasy Wool, A Method to Separate Lanolin from the Said Greasy Wool, Wool and Lanolin Obtainable by These Methods  
A method to wash wool containing lanolin and impurities includes the steps of providing a volume of an aqueous liquid at a temperature below a melting temperature of the lanolin, soaking the wool...
US20090325919 METHOD OF PREPARATION OF A SOLUBLE FORMULATION OF WATER-INSOLUBLE PENTACYCLIC AND TETRACYCLIC TERPENOIDS, A SOLUBLE FORMULATION OF A PENTACYCLIC OR TETRACYCLIC TERPENOID AND A PHARMACEUTICAL COMPOSITION CONTAINING THIS SOLUBLE FORMULATION  
The invention relates to a method of preparation of a soluble formulation of water-insoluble pentacyclic and tetracyclic terpenoids, wherein the water-insoluble terpenoid having a free carboxylic,...
US20130089884 Protein Modification from the Oxidation of Clickable Polyunsaturated Fatty Acid Analogs  
Clickable polyunsaturated fatty acid analogs, methods of using these analogs and kits comprising these analogs.
US20070255066 Epimerisation of Allylic Alcohols  
The present invention relates to processes for epimerising alcohols of compounds having a hydroxyl substituent on an asymmetric allylic carbon, such as compounds useful for the synthesis of...
US20060183720 9-Substituted tetracyclines  
This invention provides compounds of Formula (I); or a tautomer or pharmaceutically acceptable salts thereof useful as antibacterial agents.
US20110182828 C20-C21 SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS  
The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, or isomers of said compounds), having the general structure:...
US20110160167 Steroid Derivatives Acting As Glucocorticosteroid Receptor Agonists  
The present invention provides compounds of formula (I) wherein n, p, R1, R2, X1, X2, X3, R3a, R3b, R4, R5 and R6 are as defined in the specification, a process for their preparation,...
US20140005398 BORATE MOIETY-CONTAINED LINKER AND BIO-SENSING ELEMENT CONTAINING THE SAME  
A borate moiety-contained linker and a bio-sensing element containing the same are disclosed. The borate moiety-contained linker can be used to modify a sensing molecule and connect the sensing...
US20060183723 Ethercarboxylic acid ester of sterol or stanol  
The disclosed invention relates to sterol and/or stanol esters of ethercarboxylic acids corresponding to general formula (I):R(OAlk)nOCH2COOH, in which R is a C1-50 alkyl, alkenyl and/or...
US20090081297 Use of surface tension reducing agents in aerosol formulations  
The present disclosure describes aerosol formulations that are particularly effective for pulmonary aerosol delivery. The aerosol formulations comprise an aqueous dispersion of active agent...
US20100069627 NOVEL METHOD FOR THE DIASTEREOSELECTIVE PRODUCTION OF A CHIRAL PRIMARY AMINE ON A STEROID  
The invention relates to a diastereoselective method for obtaining a primary amine on a steroid, comprising the reduction of an oxime by lithium in ammonia at a low temperature in an ether/alcohol...
US20100075929 9-AMINOACYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF  
A compound of formula (I):
US20080318870 SYNTHETIC BILE ACID COMPOSITIONS AND METHODS  
Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin...
US20080249075 C11 Modified Retrosteroids as Progesterone Receptor Modulator Compounds  
Retrosteroidal compounds corresponding to formula I, representing progesterone receptor modulators, and their production, and pharmaceutical preparations containing these compounds. These...
US20100112030 ROLE OF HEDGEHOG SIGNALING IN ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASE  
The present invention provides methods and related compositions for treating or preventing cardiovascular diseases, including, e.g., atherosclerosis, using an oxysterol. In addition, the present...
US20140363780 ORAL CARE COMPOSITIONS  
Described herein are aqueous and substantially non-aqueous oral compositions comprising a cationic steroidal compound and methods of making and using the same.
US20060135797 Process for purifying diacerein  
A process for obtaining diacerein with an aloe-emodine content lower thatn 100 ppm, prefereably of 0-5 ppm, is herein disclosed. The process comprises subjecting an an aqueous-organic solution of...
US20130338383 PREGNANOLONE DERIVATIVES SUBSTITUTED IN 3ALPHA-POSITION WITH THE CATIONIC GROUP, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM  
Pregnanolone derivatives, substituted in 3 alpha-position with the cationic group, of general formula I, and a method of the production of these compounds and their utilization for treatment of...
US20130131029 ANTISOLVENT SOLIDIFICATION PROCESS  
The present invention relates to a antisolvent solidification process wherein a liquid medium comprising at least one organic or inorganic compound which is to be solidified is forced through a...
US20120232296 ANTISOLVENT SOLIDIFICATION PROCESS  
The present invention relates to a antisolvent solidification process wherein a liquid medium comprising at least one organic or inorganic compound which is to be solidified is forced through a...
US20070191317 VITAMIN D ANALOG - RAK, METHODS AND USES THEREOF  
Compounds of formula IA or IB are provided where X1, X2 and X3 are independently selected from H or hydroxy protecting groups and R1 is selected from straight or branched chain alkyl groups having...
US20150240411 NANOFIBER STRUCTURE WITH IMMOBILIZED ORGANIC SUBSTANCE AND THE METHOD OF ITS PREPARATION  
The invention concerns a nanofiber structure with immobilized organic agens that consists of silica nanofibers whose surface was modified with aminoaikyialkoxysilane and of subsequently...
US20070015741 Novel prodrugs of estradiol  
The present invention is a prodrug derivative of estradiol according to Formula I:
US20090093450 AGENT FOR INHIBITING VISCERAL FAT ACCUMULATION  
To reduce amounts of fat accumulated in abdominal cavity and to prevent or ameliorate visceral fat type obesity, considered to be a main factor of metabolic syndrome, the present invention...
US20110021466 USE OF EPICATECHIN AND DERIVATIVES AND SALTS THEREOF FOR CARDIAC PROTECTION OF ISCHEMIC MYOCARDIUM AND TO AMELIORATE ADVERSE CARDIAC REMODELING  
The disclosure provides a method of reducing infarct size in the heart following permanent ischemia or ischemia/reperfusion (IR) event or method for delaying, attenuating or preventing adverse...