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US20140249163 MALIGNANT AND NON-MALIGNANT DISEASE TREATMENT WITH RAS ANTAGONISTS  
The present disclosure describes new inhibitors or antagonists of Ras useful for the treatment of conditions resulting from Ras-induced or mediated cellular processes, including cellular...
US20120059173 DENDRITIC MOLECULES  
The invention relates to novel dendritic molecules and methods of making them. The dendritic molecules comprise arms, each of which arms is a polymer. The dendritic molecules can be synthesised by...
US20110136807 Bicyclic compositions and methods for modulating a kinase cascade  
The invention relates to compounds and methods for modulating one or more components of a kinase cascade.
US20130225826 Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes  
The present invention relates to a method for preparing 4-chloro-, 4-bromo- or 4-iodobenzaldehyde oximes and phenyl-substituted isoxazoline compounds prepared from these oximes.
US20140088308 Fluoride-Releasing Compositions  
Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials, dental bonding agents or other dental materials, to...
US20120264939 Fluoride-Releasing Compositions  
Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials, dental bonding agents or other dental materials, to...
US20130095322 NOVEL YELLOW PIGMENT COMPOSITION, AND METHOD FOR PRODUCING YELLOW PIGMENT MICROPARTICLES  
Disclosed are: a yellow pigment composition which contains at least one kind of yellow pigment microparticle having excellent transmission characteristics; and a method for producing the yellow...
US20110112160 TABLET COMPRISING EPROSARTAN MESYLATE  
A tablet comprising eprosartan mesylate in only one form of either anhydrous or dihydrate form is described. In another aspect, a tablet is disclosed comprising eprosartan mesylate obtainable by...
US20140378430 Heterocyclic Compounds and Methods of Their Use  
The present invention relates to heterocyclic compounds useful for antagonising angiotensin II Type 2 (AT2) receptor. More particularly the invention relates to pyrrolidine and azetidine...
US20140127737 VARIABLE COLOR TWO-PHOTON FLUORESCENT PROBE, METHOD FOR IMAGING THIOL ACTIVATION IN MITOCHONDRION USING SAME, AND METHOD FOR MANUFACTURING THE VARIABLE COLOR TWO-PHOTON FLUORESCENT PROBE  
The present invention relates to a two-photon fluorescent probe, more particularly a two-photon fluorescent probe represented by Formula 1, a method for preparing same and a method for imaging...
US20130303368 NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS  
Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include certain 2,5-substituted tetrazoles.
US20130259783 LINKER EXCHANGE IN ZEOLITIC IMIDAZOLATE FRAMEWORKS  
A method is provided for replacing at least a portion of the organic linker content of a zeolitic imidazolate framework composition. The method comprises exchanging the organic linker with another...
US20110144096 TREATING VARIOUS DISORDERS USING TRKB AGONISTS  
Novel compounds and methods for activating the TrkB receptor are provided. The methods include administering in vivo or in vitro a therapeutically effective amount of a compound containing four...
US20130005768 COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS  
The present invention relates to treatment and/or prevention of one or more metabolic disorders utilizing fatostatin A and/or a derivative and/or analog thereof. In other aspects, the compound for...
US20120046307 ALLOSTERIC PROTEIN KINASE MODULATORS  
The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein...
US20140142153 BENDAMUSTINE FORMULATIONS  
Aspects of the present appliction relate to pharmaceutical formulations comprising bendamustine or its pharmaceutically acceptable salts, isomers, racemates, enantiomers, hydrates, solvates,...
US20140221658 INHIBITION OF CELL PROLIFERATION  
The disclosed modulators of Rb:Raf-1 interactions are potent, selective disruptors of Rb:Raf-1 binding, with IC50 values ranging from 80 nM to 500 nM. Further, these compounds are surprisingly...
US20130084275 Methods and Compositions for Reducing Interleukin-4 or Interleukin-13 Signaling  
The present invention relates generally to methods and compositions for reducing Interleukin-4 or Interleukin-13 signaling, in particular to treat asthma and atopic dermatitis. The inventors have...
US20140005246 USE OF DITHIINE-TETRACARBOXIMIDES AS BIRD REPELLENT  
The present invention relates to the use of known dithiine-tetracarboximides as bird repellent.
US20120190125 WATER-SOLUBLE SILSESQUIOXANES AS ORGANIC QUANTUM DOTS FOR SENSING AND IMAGING  
This invention includes a compound represented by the following structural formula (I) or an acceptable salt thereof.
US20120027777 LJUNGAN VIRUS WITH IMPROVED REPLICATION CHARACTERISTICS  
The present invention relates to a Ljungan virus with improved replication characteristic and the use of this Ljungan virus, amongst other thing, in the production of a vaccine.
US20140058110 BENZOBISTHIAZOLE BUILDING BLOCKS FOR CONJUGATED POLYMERS  
A composition having the structure comprising: wherein Z is a halogen; wherein X is selected from the group consisting of N, O, P, S, and Se; wherein Y is selected from the group consisting of N,...
US20130085157 ARYLSUBSTITUTED THIAZOLOTRIAZOLES AND THIAZOLOIMIDAZOLES  
This disclosure relates to compounds, compositions and methods for the treatment of various disorders. In particular, the disclosure relates to thiazolotriazole and thiazoloimidazole compounds...
US20140205551 SUNSCREEN  
The present invention relates to a composition for topical application comprising at least a benzotriazol derivative and vitamin E or a derivative thereof. Furthermore, the invention relates to...
US20120014859 METHOD FOR PRODUCING BIS(FLUOROSULFONYL)IMIDE SALT, METHOD FOR PRODUCING FLUOROSULFATE, AND METHOD FOR PRODUCING BIS(FLUOROSULFONYL)IMIDE ONIUM SALT  
According to the method for producing bis(fluorosulfonyl)imide salt of the present invention, the method for producing fluorosulfate, and the method for producing bis(fluorosulfonyl)imide onium...
US20150152094 LIVER X RECEPTOR (LXR) MODULATORS FOR THE TREATMENT OF DERMAL DISEASES, DISORDERS AND CONDITIONS  
Described herein are liver X receptor (LXR) modulators and methods of utilizing LXR modulators in the treatment of dermal diseases, disorders or conditions. Also described herein are...
US20150045399 Liver X Receptor (LXR) Modulators For The Treatment Of Dermal Diseases, Disorders And Conditions  
Described herein are liver X receptor (LXR) modulators and methods of utilizing LXR modulators in the treatment of dermal diseases, disorders or conditions. Also described herein are...
US20110224256 THERAPEUTIC IMPRINTING FOR THE TREATMENT OF PSYCHIATRIC DISORDERS  
The invention features methods, kits, and compositions for the treatment of psychiatric disorders using therapeutic imprinting in pre-pubescent subjects.
US20110059962 TRANSCRIPTION FACTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF  
Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of using substituted benzimidazole compounds, in,...
US20150111933 Deuterated Thiazolidinone Analogues as Agonists for Follicle Stimulating Hormone Receptor  
The present invention relates to deuterated thiazolidinone analogues as agonists for follicle stimulating hormone receptor and their use for treating fertility disorders.
US20110251158 FULLERENE THERAPIES FOR INFLAMMATION AND INHIBITION OF BUILD-UP OF ARTERIAL PLAQUE  
Described herein are methods for treating inflammatory disorders or for inhibiting the build-up of arterial plaque. The methods comprise administering to a subject in need thereof a...
US20150090967 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME  
A pyrene-based compound is represented by Formula 1: where R11 to R14, L11, m11, n11, k11, a12, a13, and a14 are as defined in the specification.
US20110172435 Treatment Of Inflammatory Bowel Disease  
Disclosed herein is a method comprising administering a compound to a mammal suffering from an inflammatory bowel disease for the treatment of said disease, said compound having a structure...
US20140073760 USE OF AN ANG-(1-7) RECEPTOR AGONIST IN ACUTE LUNG INJURY  
The present invention refers to a peptidic or non-peptidic angiotensin(1-7) (Ang-(1-7)) receptor agonist, preferably a Mas receptor agonist, for the prevention and/or treatment of acute lung...
US20110281805 USE OF AN ANG-(1-7) RECEPTOR AGONIST IN ACUTE LUNG INJURY  
The present invention refers to a peptidic or non-peptidic angiotensin-(1-7) (Ang-(1-7)) receptor agonist, preferably a Mas receptor agonist, for the prevention and/or treatment of acute lung...
US20100331235 Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseases  
Histidine and/or a derivative thereof. In some embodiments, the histidine and/or a derivative thereof is used in maintaining and/or improving barrier function of the skin of a subject. In some...
US20130324577 BICYCLIC COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES  
Provided is a compound which has strong and sustaining intraocular pressure lowering action and, further, has no fear of side effect on eyes. Since a compound represented by the formula (I):...
US20140221644 NEW ROUTES TO TRANS A,B-SUBSTITUTED BACTERIOCHLORINS  
Bacteriochlorin of Formula I: wherein R is H or silyl are described, along with compositions containing the same and methods of making and using the same.
US20130183252 COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME  
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the...
US20110207937 Compounds that inhibit (block) bitter taste in composition and methods of making same  
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the...
US20120095075 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS  
The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having...
US20140038873 EQUILIBRATED DYNAMIC MIXTURES TO CONTROL THE RELEASE OF PERFUMING ALDEHYDES AND KETONES  
The present invention concerns a dynamic mixture obtained by combining, in the presence of water, at least one diamine derivative, comprising at least one heteroaryl moiety, with at least two...
US20110082144 N-HETEROARYL INDOLE CARBOXAMIDES AND ANALOGUES THEREOF, FOR USE AS GLUCOKINASE ACTIVATORS IN THE TREATMENT OF DIABETES  
This invention relates to compounds that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase...
US20150057288 PEST CONTROL AGENTS FOR HONEYBEE PARASITIC PESTS, AND PEST CONTROL METHOD FOR HONEYBEE PARASITIC PESTS USING THE PEST CONTROL AGENTS  
A pest control method for honeybee parasitic pests has been found, which is highly safe to honeybees and demonstrates excellent pest control effects against honeybee parasitic pests by using a...
US20140167001 BLUE PHOSPHORESCENCE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING THE SAME  
A blue phosphorescence compound is disclosed. The blue phosphorescence compound represented by Chemical Formula 1 below.
US20130281507 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES  
The invention relates to compounds of formula (I): The invention likewise relates to a cosmetic method for depigmenting, lightening and/or whitening keratin materials, more particularly the skin,...
US20150079298 PROCESS FOR COATING METALLIC SURFACES WITH COATING COMPOSITIONS CONTAINING PARTICLES OF A LAYERED DOUBLE HYDROXIDE  
Coating a metallic surface with at least one of a pretreatment composition prior to organic coating, with a passivation composition without intent for subsequent organic coating, with a...
US20130041134 METHODS FOR PREPARING POLYETHYLENE GLYCOL MALEIMIDE USING N-(2-HYDROXYETHYL) MALEIMIDE AS A STARTING MATERIAL  
The present invention relates generally to methods for preparing polyethylene glycol maleimide (“PEG-Mal”). More specifically, the present invention relates to methods for synthesizing desired...
US20140138652 BLUE PHOSPHORESCENCE COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING THE SAME  
A blue phosphorescence compound and an organic light emitting diode using the same are disclosed. The blue phosphorescence compound is represented by Chemical Formula 1 below: wherein ‘A’ and ‘B’...
US20120196905 SYNTHETIC COMPOUNDS AND METHODS TO DECREASE NICOTINE SELF-ADMINISTRATION  
Methods and small molecule compounds for smoking and CNS disease harm reduction are provided. One example of a class of compounds that may be used is represented by the compound having the...