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US20120053214 THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF  
The invention provides small molecule compounds capable of accelerating proliferation of stem cells and uses thereof. The compounds play an important role in the research of stem cell...
US20140235688 TREATMENT OF EXTERNAL PARASITES BY ORAL ADMINISTRATION OF PARASITICIDAL AGENTS  
Pharmaceutically acceptable compositions of fipronil for oral delivery to mammals and methods for use of the compositions to control external parasites, such as fleas and ticks.
US20090275624 INHIBITORS OF CDC PHOSPHATASES  
A subject of the present invention is novel compounds comprising 2 or 3 benzothiazole-4,7-dione- or benzooxazole-4,7-dione-type units, which inhibit the cdc25 phosphatases, in particular cdc25-C...
US20120016449 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS  
Methods and devices related to the treatment of diseases using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for...
US20140017701 CHIMERIC PDK1 KINASES  
The invention provides chimeric 3-phosphoinositide-dependent protein kinase 1 (PDK1), the PIF-binding pocket of which has mutations to mimic a second protein kinase, its production and use. The...
US20120184580 SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS OF USE THEREOF  
Substituted di-arylhydantoin and di-arylthiohydantoins are provided and may find use as androgen receptor modulators. The compounds may find particular use in treating prostate cancer, including...
US20110288076 Sphingosine-1-Phosphate Receptor Antagonists  
This disclosure relates to sphingosine-1-phosphate (S1P) receptor antagonists, compositions comprising the S1P receptor antagonists and methods for using and processes for making the S1P receptor...
US20120209003 METHODS FOR IDENTIFYING AND USING MarR FAMILY POLYPEPTIDE BINDING COMPOUNDS  
Methods for identifying MarR family inhibiting compounds are described. The methods include the use of computer aided rational based drug design programs and three dimensional structures of MarR...
US20110015375 Methods for Identifying and Using MarR Family Polypeptide Binding Compounds  
Methods for identifying MarR family inhibiting compounds are described. The methods include the use of computer aided rational based drug design programs and three dimensional structures of MarR...
US20110311505 Photosensitive Aminoacid-Monomer Linkage and Bioconjugation Applications in Life Sciences and Biotechnology  
This invention is related to preparation of photosensitive ruthenium based aminoacid monomers and oligomers, aminoacid monomer-protein cross-linking using photo sensitat ion and conjugation on...
US20120276006 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING  
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds...
US20130281504 Reduction of Microglia-Mediated Neurotoxicity by KCa3.1 Inhibition  
Methods for deterring microglia-mediated neurotoxicity in a human or non-human animal subjects comprising the step of inhibiting or blocking the intermediate-conductance calcium-activated...
US20120316148 Compositions and Methods for Modulating a Kinase  
The invention relates to compounds and methods for modulating one or more components of a kinase signaling cascade.
US20130252964 Compounds And Methods For Treating Candidiasis And Aspergillus Infections  
The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for killing or inhibiting the growth of a Candida or Aspergillus species or preventing or treating a mammal...
US20100204465 REFINED ROUTES TO CHLORIN BUILDING BLOCKS  
A method of making chlorins comprises the steps of reacting (e.g. condensing) a dipyrrin western half intermediate with an eastern half intermediate to form a tetrahydrobilene, and then cyclizing...
US20140073656 SERMS for the Treatment of Estrogen Receptor-Mediated Disorders  
Novel compounds for the treatment of estrogen receptor-mediated disorders, including breast cancer, and methods of treatment using the novel compounds. The novel compounds, when administered in a...
US20120259127 PROCESS FOR THE RESOLUTION OF ENANTIOMERS BY PREFERENTIAL EVAPORATIVE CRYSTALLIZATION  
A process for the resolution of two enantiomers which involves inducing the preferential crystallization of one enantiomer by adjusting the composition of a suspension or solution including a...
US20150105250 METAL-ORGANIC FRAMEWORKS FOR OXYGEN STORAGE AND AIR SEPARATION  
Adsorption systems providing a capacity of at least 200 g/L for oxygen-containing mixtures, or an oxygen-nitrogen selectivity of at least 1.4:1 or at least 1:2 with an adsorbed capacity of at...
US20110305645 CRYSTAL FORM OF GLYCOPYRRONIUM CHLORIDE  
A new crystal form of threo glycopyrronium chloride is useful in pharmaceutical applications.
US20110104305 COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT  
Methods for therapy of cystic fibrosis and other conditions such as cancer are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a...
US20140243341 BROAD-SPECTRUM ANTIVIRALS AGAINST 3C OR 3C-LIKE PROTEASES OF PICORNAVIRUS-LIKE SUPERCLUSTER: PICORNAVIRUSES, CALICIVIRUSES AND CORONAVIRUSES  
Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl α-ketoamides, peptidyl bisulfite salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and...
US20150021555 DONOR-ACCEPTOR COMPOUNDS WITH NITROGEN CONTAINING HETEROPOLYAROMATICS AS THE ELECTRON ACCEPTOR  
Luminescent materials including donor-acceptor compounds with a high triplet energy heteropolyaromatic system, namely, dibenzofuran, dibenzothiophene and dibenzoselenophene with one or multiple...
US20140303328 CROSS-LINKER  
Disclosed are novel cross-linkable end-cappers for oligo- and polyamides. End-capped oligo- and polyamides comprising such an end-capper may be cured at a lower temperature compared to oligo- and...
US20130225769 CROSS-LINKER  
Disclosed are novel cross-linkable end-cappers for oligo- and polyamides. End-capped oligo- and polyamides comprising such an end-capper may be cured at a lower temperature compared to oligo- and...
US20140341776 THIOPHENE BASED OLIGOMERS AS LIGHT ACTIVATED BIOCIDES  
Thiophene containing water-soluble oligomers were synthesized and characterized. The photophysical properties of these compounds were studied; transient absorption spectroscopy was used to probe...
US20110263545 HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS  
The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against...
US20150174131 NOVEL KINASE MODULATORS  
The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of...
US20110118257 NOVEL KINASE MODULATORS  
The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of...
US20130197235 Hybrid Zeolitic Imidazolate Frameworks: Controlling Framework Porosity and Functionality by a Mixed-Ligand Synthetic Approach  
Metal-organic frameworks, in particular hybrid zeolitic imidazolate frameworks (ZIFs), devices having hybrid ZIFs, and methods for preparing hybrid ZIFs are disclosed herein. In some embodiments,...
US20130296166 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES  
Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.
US20130217570 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES  
Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.
US20110028320 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES  
Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.
US20130345271 POLYMORPHIC, CRYSTALLINE AND MESOPHASE FORMS OF SODIUM 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO) ACETATE, AND USES THEREOF  
Crystalline polymorphs and solid mesophase forms of sodium 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol -3-ylthio)acetate are described. In addition, pharmaceutical compositions...
US20120129903 POLYMORPHIC, CRYSTALLINE AND MESOPHASE FORMS OF SODIUM 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO) ACETATE, AND USES THEREOF  
Crystalline polymorphs and solid mesophase forms of sodium 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol -3-ylthio)acetate are described. In addition, pharmaceutical compositions...
US20150026842 METHOD OF CONTROLLING SUDDEN DEATH SYNDROME WITH FLUTRIAFOL  
This invention relates to the use of the compound flutriafol for protecting plants and plant propagation material from Sudden Death Syndrome. The use comprises applying a composition comprising...
US20130131099 COMPOUNDS AND METHODS OF TREATING BRAIN DISORDERS  
Nitrated and non-nitrated compounds capable of protecting brain tissue from injury and useful as therapeutic agents to treat neurodegenerative diseases and conditions are disclosed. Methods of...
US20150119406 TRICYCLIC PYRONE COMPOUNDS REDUCE AMYLOID BETA AGGREGATES  
Tricyclic pyrone compounds having high oral bioavailability, excellent blood-brain barrier permeability, and low toxicity are presented. Administration of the compounds to Alzheimer's Disease...
US20140113012 COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS  
The present invention provides compounds and compositions for the amelioration of arthritis and joint injuries by inducing mesenchymal stem cells into chondrocytes.
US20150174261 CATIONIC LIPID  
Provided are a cationic lipid which facilitates the introduction of a nucleic acid into, for example, a cell or the like; a composition containing the cationic lipid and a nucleic acid; a method...
US20130034731 ADJUVANT CONTAINING beta-HEMATIN  
The present invention is directed to providing a method for preparing a vaccine adjuvant composition containing β-hematin and a vaccine adjuvant composition obtained by the preparation method. The...
US20140213623 COMPOUNDS FOR TREATMENT OF CANCER  
The present invention relates to a compound of formula XXII and a compound of formula 17ya, which are defined as anywhere in the specification, to a composition comprising the same, and to a...
US20110198578 SILOLES SUBSTITUTED BY FUSED RING SYSTEMS AND USE THEREOF IN ORGANIC ELECTRONICS  
The present invention relates to the use of siloles substituted by fused ring systems in organic electronics applications, and to specific siloles substituted by fused ring systems and to the use...
US20150010921 Cell Death Assay  
The present invention relates to a method for detecting cell death using a luminescent compound; to the luminescent compounds for particular uses; to a kit comprising compounds and to a protein....
US20140194463 COMPOSITIONS FOR TREATMENT OF CANCER  
Compounds that are specifically toxic to cancer stem cells are disclosed.
US20140194429 COMPOSITIONS FOR TREATMENT OF CANCER  
Compounds that are specifically toxic to cancer stem cells are disclosed.
US20140066418 CONSTRUCTION MATERIAL PRESERVATIVE  
The present invention provides a construction material preservative for wood and the like that retains preservative effects over a long period of time and continuously demonstrates those effects...
US20110135738 SINGLE DOSAGE PHARMACEUTICAL FORMULATION COMPRISING EPROSARTAN MESYLATE  
A dry formulation or granulation of eprosartan mesylate is described which comprises eprosartan mesylate in particulate form with a particle size, wherein at least 65 v/v % eprosartan mesylate...
US20110263567 COMPOUNDS FOR INHIBITING SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) / VASCULAR ADHESION PROTEIN-1 (VAP-1) AND USES THEREOF FOR TREATMENT AND PREVENTION OF DISEASES  
The present invention relates to compounds of general formula (i) having an oxime moiety or a pharmaceutically acceptable salt, hydrate or solvate thereof and its use for inhibiting...
US20100298389 Novel Imaging Tracers for Early Detection and Treatment of Amyloid Plaques Caused by Alzheimer's Disease and Related Disorders  
The present invention relates to compounds and methods for imaging and treating Alzheimer's disease or an amyloidosis-associated pathological condition that utilize a novel amyloid imaging tracer...
US20110028364 FRICTION MODIFIER AND TRANSMISSION OIL  
A bis-type alkenyl-substituted succinimide which is prepared by reaction of succinic anhydride substituted with 2-alkenyl group having a branch structure in β-position with alkylenepolyamine and...