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US20140288312 COMPOUNDS FOR THE TREATMENT OF INFLUENZA  
The invention relates to oseltamivir derivatives as influenza neuraminidase inhibitors for treating influenza infections and to a method for producing said compounds.
US20130175509 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME  
Embodiments of the present invention are directed to a condensed-cyclic compound and an OLED including the same.
US20140182680 ELECTROLYTE FORMULATIONS  
The present invention relates to electrolyte formulations comprising at least one compound comprising a dihydridodicyanoborate anion and their use in an eletrochemical and/or optoelectronic device...
US20120295874 COFERONS AND METHODS OF MAKING AND USING THEM  
The present invention is directed to a monomer useful in preparing therapeutic compounds. The monomer includes one or more pharmacophores which potentially binds to a target molecule with a...
US20110130402 HETEROAROMATIC GLUCOKINASE ACTIVATORS  
The present invention describes 2,3-di-substituted N-heteroaromatic propionamides, wherein the substitution at the 3-position is an optionally substituted phenyl ring and the substitution at the...
US20080249148 Synthesis and characterization of polymorph form III 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzonitrile  
A polymorph Form III of 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzoni trile and methods of preparing Form III are described. Also provided are methods of contraception, treating or...
US20120251491 FUSED TRICYCLIC ARYL COMPOUNDS USEFUL FOR THE TREATMENT OF VIRAL DISEASES  
The present invention relates to novel Fused Tricyclic Aryl Compounds, compositions comprising at least one Fused Tricyclic Aryl Compound, and methods of using the Fused Tricyclic Aryl Compounds...
US20140308360 NANOPARTICLES AND NANOPARTICLE COMPOSITIONS  
The invention provides multivalent surface-crosslinked micelle (SCM) particles, crosslinked reverse micelle (CRM) particles, and methods of making and using them. The SCM particles can be used,...
US20130101516 NANOPARTICLES AND NANOPARTICLE COMPOSITIONS  
The invention provides multivalent surface-crosslinked micelle (SCM) particles, crosslinked reverse micelle (CRM) particles, and methods of making and using them. The SCM particles can be used,...
US20080025940 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof  
3-Sulfanylpropanamide compounds of formula (I) or salts and/or solvates thereof: are useful for caring for and/or making up keratin fibers, especially human keratin fibers, to induce and/or...
US20110286995 Drug Therapy for Celiac Sprue  
Administering an effective dose of a tTGase inhibitor to a Celiac or dermatitis herpetiformis patient reduces the toxic effects of toxic gluten oligopeptides, thereby attenuating or eliminating...
US20110028656 Band gap control in conjugated oligomers and polymers via Lewis acids  
A method for altering the electronic and optical properties of a chemical compound having a band gap and a framework that includes π-delocalized electrons. The method includes complexing a Lewis...
US20120330028 METHOD FOR PREPARING POLYBIOTINYLATED COMPOUNDS  
The present invention relates to a novel method for preparing compounds having the formula (I), where X is biotin or Y being biotin or Z being biotin or V being biotin or It also relates to...
US20140287640 Functionalized Ionic Liquids and Their Applications  
Disclosure of functionalized ionic liquids. Use of disclosed ionic liquids as solvent for carbon dioxide. Use of disclosed ionic liquids as flame retardant. Use of disclosed ionic liquids for...
US20150246348 Z-SELECTIVE RING-CLOSING METATHESIS REACTIONS  
The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.
US20120323000 Z-SELECTIVE RING-CLOSING METATHESIS REACTIONS  
The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.
US20140315965 BIS-(ARYL/HETEROARYL)-METHYLENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND THEIR USE FOR TREATING CANCER  
The present disclosure relates to novel compounds having vitamin D receptor agonist and histone deacetylase inhibitory efficacy as well as methods for reducing or inhibiting the proliferation of...
US20110086369 FLUORESCENT COMPOUNDS FOR THE DIAGNOSIS OF INFECTIONS, PRODUCTION METHOD, AND APPLICATIONS THEREOF  
The present invention describes novel fluorescent compounds analogous to alkyl phospholipids, containing highly photostable fluorescent groups in the structure thereof and emitting in the visible...
US20110112091 DERIVATIVES OF TETRABROMOBENZIMIDAZOLE, A PROCESS FOR THE PREPARATION THEREOF, A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, A METHOF OF USING THE SAME, A METHOD FOR MODULATING OR REGULATING SERINE/THREONINE KINASES, AND SERINE/THREONINE KINASES MODULATING AGENT  
A derivative of tetrabromobenzimidazole, a process for the preparation thereof, a pharmaceutical composition, a method for using the same, a method for modulating or regulating serine/threonine...
US20070043079 Heterocyclic compound containing nitrogen atom and use thereof  
The present invention relates to a medicament comprising the compound of formula (I) wherein all symbols have the same meanings as defined in the specification, a salt thereof or a prodrug...
US20140005407 METHOD OF PREPARING RADIOISOTOPE NANOSTRUCTURE WITH LIGAND-METAL FRAMEWORK AND APPLICATION  
This invention relates to a method of preparing a radioisotope nanostructure having a ligand-metal framework, and a radioisotope nanostructure prepared thereby. The method of preparing the...
US20090318516 SOLID FORMS OF (1R,2S,3R)-1-(2-(ISOXAZOL-3-YL)-1H-IMIDAZOL-4-YL)BUTANE-1,2,3,4-TETRAOL AND METHODS OF THEIR USE  
Solid forms of (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2, 3,4-tetraol and hydrates thereof are disclosed, as well as compositions comprising them and methods of their use.
US20110223613 METHOD OF IMAGING BY MASS SPECTROMETRY AND NEW MASS TAG ASSOCIATED TRITYL DERIVATIVES  
The present invention concerns a method of analyzing at least one specific molecule in a sample using a compound of formula (I″) wherein Z binds specifically to said at least one specific...
US20110294118 WATER SOLUBLE FLUORESCENT COMPOUNDS  
The invention provides a novel class of fluorescent compounds. Also provided are conjugates of the fluorescent compounds, methods of using the fluorescent compounds and their conjugates as well as...
US20120022083 SMALL MOLECULE MODULATORS OF CELL ADHESION  
Compounds, particularly compounds having activity as modulators of cadherin-mediated cell adhesion having the following structure: or a pharmaceutically acceptable salt, stereoisomer or prodrug...
US20090005391 Tricyclo Substituted Amides  
Compounds of Formula (I) or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
US20080293741 Tricyclo Substituted Amides as Glucokinase Modulators  
Compounds of Formula (I): (I) or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
US20150218112 COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS THAT ARE AMELIORATED BY INHIBITION OF HDAC  
The present invention relates to compounds of formula (I) and (IV), and pharmaceutically acceptable salts, tautomers, stereoisomers thereof, which are inhibitors of histone deacetylase (HDAC). The...
US20140329875 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING DISEASE CONDITIONS, INCLUDING METABOLIC DISORDERS AND CANCERS  
The present invention provides novel, diastereomeric pyrazolines that are useful as cannabinoid receptor blockers and pharmaceutical compositions thereof and methods of using the same for treating...
US20140031404 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING DISEASE CONDITIONS, INCLUDING METABOLIC DISORDERS AND CANCERS  
The present invention provides novel, diastereomeric pyrazolines that are useful as cannabinoid receptor blockers and pharmaceutical compositions thereof and methods of using the same for treating...
US20140371284 IMIDAZOLIDINEDIONE COMPOUNDS AND THEIR USES  
Provided are imidazolidinedione compounds of formula (I), processes for preparation, uses and pharmaceutically compositions thereof. Said imidazolidinedione compounds posses androgen receptor...
US20140371202 INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME  
The present teaching provide indazole compounds represented by Structural Formulae (I) or (I′) or a pharmaceutically acceptable salt thereof. Also described are pharmaceutical compositions and...
US20120208786 BISPHOSPHONATE COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE  
The present invention provides for methods and compositions for treating and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate,...
US20130280305 CATIONIC LIPID  
The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I) (wherein: R1 and R2 are, the same or different, alkenyl,...
US20130108685 CATIONIC LIPID  
The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I) (wherein: R1 and R2 are, the same or different, alkenyl,...
US20120245185 ARYL AND HETEROARYL SULFONES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION  
In one aspect, the invention relates to sulfone compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4);...
US20140077175 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE CONDENSED-CYCLIC COMPOUND  
A condensed-cyclic compound and an organic light-emitting diode including the condensed-cyclic compound.
US20120238607 SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF  
The present application relates to new, substituted 2-acetamido-5-aryl-1,2,4-triazolones, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention...
US20110053901 ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE  
Among other things, the present invention provides novel compounds capable of effectively inhibiting inflammatory responses that are mediated by G-proteins or GPCRs in neutrophils, macrophages and...
US20140018340 Insulin Mimetic Active Comprising Oxodiperoxo Vanadates and a Pharmaceutical Composition Obtained Thereof  
A pharmaceutically acceptable peroxovanadium(v) amine product, DmpzH[VO(02)2](Dmpz)], and its oral as well as injectable use for the treatment of Diabetes mellitus, wherein the said...
US20150259296 BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN  
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders...
US20150141465 COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN  
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders...
US20150133430 COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN  
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders...
US20140275176 Compounds and uses thereof for the modulation of hemoglobin  
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders...
US20140275152 Compounds and uses thereof for the modulation of hemoglobin  
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders...
US20140275008 Compounds and uses thereof for the modulation of hemoglobin  
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders...
US20100298387 IL-8 Receptor Antagonists  
This invention relates to novel compounds, compositions and combinations thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
US20140296466 Method for Producing Bio-Based Homoserine Lactone and Bio-Based Organic Acid from O-Acyl Homoserine Produced by Microorganisms  
The present invention relates to a method of producing bio-based homoserine lactone and bio-based organic acid through hydrolysis of O-acyl homoserine produced by a microorganism in the presence...
US20150005507 CRYSTALLINE POLYMORPHS OF ISOXAZOLINE COMPOUND AND PRODUCTION METHOD THEREOF  
A method for manufacturing a crystal and a crystal of (S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydr oisoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylami no)ethyl]benzamide...
US20150203505 INDOLE CARBOXAMIDE DERIVATIVE  
[Problem] To provided a compound which is useful as an MT1 and/or MT2 receptor agonist.[Means for Solution]The present inventors have conducted studies on MT1 and/or MT2 receptor agonists, and...