Match Document Document Title
US20140314779 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION  
Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides,...
US20130310570 METHODS INCLUDING LATENT 1,3-DIPOLE-FUNCTIONAL COMPOUNDS AND MATERIALS PREPARED THEREBY  
Methods that include latent 1,3-dipole-functional compounds are disclosed herein. The latent 1,3-dipole-functional compound (e.g., an oxime) can be used to form an active 1,3-dipole-functional...
US20140155262 Fungicidal substituted 2-[2-halogenalkyl-4-(phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds  
The present invention relates to substituted 2-[2-halogenalkyl-4-(phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl- ethanol compounds of formula I as defined in the description, and the N-oxides, and salts...
US20140141974 Fungicidal phenylalkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds  
The present invention relates to phenylalkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1- yl-ethanol compounds of formula I as defined in the description, and the...
US20140364464 CRYSTALLINE FORMS OF AZILSARTAN MEDOXOMIL POTASSIUM AND PREPARATION AND USES THEREOF  
The present invention relates to the field of pharmaceutical chemistry. Disclosed herein is a crystalline form of azilsartan medoxomil potassium, which is substantially pure. The crystalline form...
US20150238498 COMPOUNDS FOR THE TREATMENT OF PARAMOXYVIRUS VIRAL INFECTIONS  
Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein...
US20120282337 Modified Release Formulation  
The invention is directed to the use of an extended release tablet formulation for pramipexole.
US20110150994 Modified Release Formulation  
The invention is directed to the use of an extended release tablet formulation for pramipexole.
US20120149693 THERAPEUTIC COMPOUNDS  
The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for...
US20140356336 METHOD FOR INDUCING DIFFERENTIATION ENABLING TUMORIGENESIS OF IPS CELLS TO BE SUPPRESSED  
The object of the invention is to provide a technique of suppressing tumorigenesis in IPS cells and inducing differentiation into target differentiated cells. In use of a statin and a...
US20110319429 SUBSTITUTED 1,1,3,1-TETRAOXIDOBENZO[D][1,3,2]DITHIAZOLES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION  
Compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) and methods of using the compounds.
US20150252037 SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS  
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such...
US20140039183 SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS  
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such...
US20110183953 SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS  
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such...
US20140077190 PHOSPHINE OXIDE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME  
A phosphine oxide-based compound represented by Formula 1, and an organic light-emitting device including the phosphine oxide-based compound. wherein Ar1 through Ar3, and a, b, and c are defined...
US20130131042 SPIROXAZOLIDINONE COMPOUNDS  
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of...
US20130184318 MODULATING COMPLIANCE OF TRABECULAR MESHWORK  
The present invention provides methods of determining the effect of test agents on the compliance of trabecular meshwork (TM) tissue, at the level of the extracellular matrix (ECM) and/or cells...
US20140315957 ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF  
The present invention relates to novel substituted thioimidazolidinone compounds and pharmaceutical compositions comprising such compounds for treatment of androgen receptor-associated diseases or...
US20120172406 ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF  
The present invention relates to novel substituted thioimidazolidinone compounds and pharmaceutical compositions comprising such compounds for treatment of androgen receptor-associated diseases or...
US20130338116 COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES  
The present invention relates generally to pharmaceutical agents, and in particular, to metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of dual...
US20110230452 Compounds and methods for the treatment of pain and other diseases  
The present invention relates generally to pharmaceutical agents, and in particular, to metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of dual...
US20150164865 ORAL FORMULATIONS OF DIPHENYLSULFONAMIDE ENDOTHELIN AND ANGIOTENSIN II RECEPTOR AGONISTS TO TREAT ELEVATED BLOOD PRESSURE AND DIABETIC NEPHROPATHY  
Methods of administering and pharmaceutical compositions of a biphenyl sulfonamide compound which is a dual angiotensin and endothelin receptor antagonist are disclosed for treating diseases.
US20140142149 ORAL FORMULATIONS OF DIPHENYLSULFONAMIDE ENDOTHELIN AND ANGIOTENSIN II RECEPTOR AGONISTS TO TREAT ELEVATED BLOOD PRESSURE AND DIABETIC NEPHROPATHY  
Methods of administering and pharmaceutical compositions of a biphenyl sulfonamide compound which is a dual angiotensin and endothelin receptor antagonist are disclosed for treating diseases.
US20150099165 ELECTROLYTE ADDITIVE FOR A LITHIUM-BASED ENERGY STORAGE DEVICE  
The invention relates to an electrolyte for a lithium-based energy storage device comprising at least one lithium salt, a solvent and at least one compound of general formula (1), and to their use...
US20120225922 Effective Amounts of (3aR)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo [2,3-b]indol-5-yl Phenylcarbamate and Methods of Treating or Preventing Neurodegeneration  
The invention includes an amount of (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b] indol-5-yl phenylcarbamate for administering to a subject and also a method of preventing or...
US20120264948 MEMBRANE SEPARATION AND PURIFICATION OF MONATIN  
Methods and systems for separating and purifying monatin are described. In the production of monatin, a mixture is formed which includes monatin, starting materials and intermediates. The methods...
US20140121299 ADDUCTS AS TOUGHENERS IN THERMOSETTABLE EPOXY SYSTEMS  
A liquid adduct consisting essentially of a reaction product of (a) an aliphatic epoxy resin, and (b) an isocyanate compound, wherein the viscosity of the adduct comprises less than about 60 Pa-s...
US20150080412 TRIAZOLONE COMPOUNDS AND USES THEREOF  
The invention disclosed herein is directed to compounds of Formula (I) and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic,...
US20140045794 Phosphonate Compounds  
The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis...
US20130045950 Phosphonate Compounds  
The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis...
US20110294827 IAP BINDING COMPOUNDS  
IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in...
US20130150591 METHOD FOR PURIFYING N-ALKYL-SUBSTITUTED PYRROLIDONES BY HYDROGENATION  
The invention relates to a method for purifying N-alkyl-substituted pyrrolidones which have contaminants with a higher degree of oxidation, by hydrogenation of the same and distillation.
US20100325754 Compositions and methods for modulating oxidative burst in plant transformation  
A method for introducing a nucleic acid sequence into the genome of a plant cell and regenerating a transformed plant therefrom, including culturing the plant cell on at least one plant...
US20130196996 USE OF ISOXAZOLINE COMPOUNDS AND COMPOSITIONS IN BLADDER CANCER  
One embodiment provides a method, comprising treating or preventing at least one disease selected from the group consisting of bladder cancer, weight loss accompanying bladder cancer, bone pain...
US20140239269 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME  
A pyrene-based compound, and an organic light-emitting diode including the pyrene-based compound are provided.
US20140167007 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME  
A pyrene-based compound and an organic light-emitting diode including the pyrene-based compound are provided.
US20130331426 pH-SENSITIVE COMPOSITIONS FOR DELIVERY OF BETA LAPACHONE AND METHODS OF USE  
Disclosed herein are compounds comprising a polymer conjugated with a pH-sensitive prodrug of beta-lapachone, wherein the compound is capable of forming a micelle, and wherein the pH-sensitive...
US20150191417 ANTI-PROLIFERATIVE COMPOUNDS AND USES THEREOF  
The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, tautomers, stereoisomers, solvates, hydrates, polymorphs, and compositions thereof. Also...
US20140309427 Substituted Pyran Derivatives  
Certain 3,6-disubstituted and 2, 4, 5-trisubstituted pyran derivatives that exhibit potent activity on monoamine transport systems are provided. The 3, 6 and 2, 4, 5 pyrans are useful in probing...
US20110306498 METHOD OF RESTORING MALE STERILITY IN GRAMINEOUS PLANTS AND MALE STERILITY RESTORATIVE AGENT  
The present invention provides a method and a composition for restoring pollen fertility by suppressing formation insufficiency in a pollen formation process due to a high-temperature or...
US20150218148 Benzothiazole Or Benzoxazole Compounds As Sumo Activators  
Provided are SUMO activators, which can enhance SUMOylation of SERCA2a, which are useful in the treatment of heart failure, cardiovascular diseases, cancer, neurodegenerative disorders, viral...
US20130324556 Protease Activated Receptor 2 (PAR2) Antagonists  
A compound of formula (I) or a pharmaceutically acceptable salt, solvate, or hydrate thereof Wherein Y, Z, R3, U, R4, m and n are as defined in the claims.
US20130296576 HIGH STABLE NON-IONIC N-VINYL BUTYROLACTAM IODINE AND PREPARATION METHOD THEREOF  
The present invention relates to a preparation method of a high-stable non-ionic N-vinyl butyrolactam iodine, wherein non-ionic N-vinyl butyrolactam, iodine and at least one grinding aid are...
US20100203135 Skin Equivalent Culture  
Methods of forming soft connective tissue compositions such as skin equivalents, compositions made by the methods and their uses. In particular, a method of forming a connective tissue equivalent,...
US20150010474 Compounds And Methods For Selective Imaging And/Or Ablation  
The invention relates generally to compounds and methods for imaging and/or selective ablation of nitroreductase-expressing cells and/or biological agents. More particularly, although not...
US20150239824 BRANCHED OR MACROCYCLIC POLYAMINES AND USES THEREOF  
The present invention relates to synthetic polyamines and their polyammonium derivatives and their use as a pharmacological or biological research tool or as a therapeutic agent.
US20150045395 METHOD OF USING AN INDOLINONE MOLECULE AND DERIVATIVES FOR INHIBITING LIVER FIBROSIS AND HEPATITIS  
This invention relates to methods of reversing and inhibiting liver fibrosis and hepatitis using a small indolinone molecule Hesperadin and related compounds. Methods of identifying such agents...
US20140336394 EMM-23 Molecular Sieve Materials, Its Synthesis and Use  
A new molecular sieve material is designated as EMM-23 and has, in its as-calcined form, an X-ray diffraction pattern including the following peaks in Table 1: TABLE 1d-spacing (Å)Relative...
US20150105560 FORMULATION COMPRISING IONIC ORGANIC COMPOUNDS FOR USE IN ELECTRON TRANSPORT LAYERS  
The invention relates to formulations comprising ionic organic compounds for use in electron transport layers or electron collecting layers of organic electronic (OE) devices, more specifically in...
US20100298168 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions  
Capture compounds and collections thereof and methods using the compounds for the analysis of biomolecules are provided. In particular, collections, compounds and methods are provided for...