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US20090306175 |
HETEROCYCLIC ARYLSULPHONES SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR
The invention relates to compounds of the formula (I) wherein the variables have meanings given in the claims and the description. The invention also relates to the use of a compound of the formula...
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US20090227635 |
THERAPEUTIC COMPOUNDS
Compounds comprising
or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein Y, A, B, and J are as described. Methods, compositions, and medicaments related thereto...
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US20090186873 |
KAPPA SELECTIVE OPIOID RECEPTOR ANTAGONIST
A selective kappa opioid receptor antagonist useful for treating ethanol use disorder withdrawal and anxiety, and/or depression, or schizophrenia as independent comorbid conditions.
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US20090163482 |
TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR
This invention is directed to a compound of formula (I), as defined herein, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing a compound of formula (I) a...
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US20080261952 |
Aryl Urea Derivatives for Treating Obesity
A method of treating a condition associated with the CB-1 receptor, in particular obesity, by administering an effective amount of an aryl urea CB-1 receptor modulating compound to a subject in...
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US20080176864 |
Substituted N-Arylpyrrolidines as Selective Androgen Receptor Modulators
The present invention provides a compound of the Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I)...
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US20080167468 |
Silacycle compounds and methods of use thereof
The present invention relates to a diastereomeric mixture of Silacycle Compounds and methods for using the diastereomeric mixture of Silacycle Compounds for stereoselective synthesis.
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US20080167361 |
Arylsulfonyl pyrrolidines as 5-HT6 inhibitors
Compounds of the formula I:
wherein m, n, Ar, R 1 and R 2 are as defined herein. Methods of making the compounds and using the compounds are disclosed.
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US20080032981 |
ARYL N-CYANOGUANIDINES AND METHODS RELATED THERETO
Compounds, compositions and methods treating arthritic disorders such as osteoarthritis or rheumatoid arthritis, and for treating other diseases associated with altered mitochondrial function, such...
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US20080009619 |
PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS
The invention relates to a novel process for the preparation of asenapine, i.e. trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:
6,7]oxepino[4,5-c]pyrrole, as well as to novel...
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