|
Match
|
Document |
Document Title |
|
|
US20090292129 |
PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST
A process for resolving a compound in racemic form comprising the following steps is described: a) reacting a compound in racemic form with a resolving agent, b) forming a diastereoisomeric complex...
|
|
|
US20090227593 |
CYCLOBUTYL AMINE DERIVATIVES
Compounds of formula (I)
are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the...
|
|
|
US20090124664 |
(R)-Arylalkylamino Derivatives and Pharmaceutical Compositions Containing Them
The present invention relates to selected (R)-arylalkylamino derivatives of formula (I), in which R, R1 and Ar are as defined in the claims. These compounds show a surprising potent inhibitory...
|
|
|
US20090062366 |
Pyrrolidine derivative or salt thereof
[Problem] To provide a compound which may be used in treating diseases in which a calcium sensing receptor (CaSR) is concerned, particularly hyperparathyroidism. [Means for Resolution] It was...
|
|
|
US20090029962 |
2-AZETIDINEMETHANEAMINES AND 2-PYRROLIDINEMETHANEAMINES AS TAAR-LIGANDS
The present invention relates to compounds of formula I
wherein
R 1 , R 2 , R 3 , Ar, n and o are as defined herein and to their pharmaceutically acceptable active salts. Compounds of formula I...
|
|
|
US20090023935 |
Process for Producing 3,4-Disubstituted Pyrrolidine Derivative and Production Intermediate Thereof
An industrially advantageous process for the production of (3R,4S)-3-cyclopropylaminomethyl-4-fluoropyrrolidine or an enantiomer thereof that is useful as an intermediate for the production of...
|
|
|
US20080287506 |
Insecticidal N,N-Di(Heteroarylalkyl) Amine Derivatives
Certain novel N,N-di(heteroarylalkyl)amine derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula (I): wherein Ar Ar 1 , a, b, c, R, R...
|
|
|
US20080176906 |
Substituted Pyrrole Derivative
The present invention provides a novel pyrrole derivative having excellent androgen receptor antagonism, which is represented by the formula:
wherein R 1 represents a hydrogen atom, a cyano...
|
|
|
US20080146649 |
Substituted pyrrolidine and related compounds
This invention is directed to compounds of formula I:
wherein R 1 -R 5 and a-e are as defined in the specification; or pharmaceutically-acceptable salt or solvate or stereoisomer thereof....
|
|
|
US20080138704 |
Material for Electrolytic Solution, Ionic Material-Containing Composition and Use Thereof
An object of the present invention is to provide a material for an electrolytic solution having improved ionic conductivity and, showing excellent in low temperature property, being stable with...
|
|
|
US20080096934 |
Aminoethylaromatic Compounds Suitable For Treating Disorders That Respond To Modulation Of The Dopamine D3 Receptor
The present invention relates to aromatic compounds of the formula I
wherein Ar is phenyl or an aromatic 5- or 6-membered C-bound heteroaromatic radical, wherein Ar may carry 1 radical R a ...
|
|
|
US20080071083 |
Methods for minimizing thioamide impurities
Methods for minimizing the formation of thioamide compounds using decoy agents during reactions, such as thionations of carbonyl compounds containing nitrile groups, and the products thereby are...
|
|
|
US20080058528 |
Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile
A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)p
iperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are...
|
|
|
US20080045504 |
Benzonitrile Derivatives to Treat Musculoskeletal Frailty
This invention relates to novel amino substituted benzonitrile derivatives and to pharmaceutical compositions containing the novel amino substituted benzonitrile derivatives. This invention also...
|
|
|
US20080027037 |
Cyclic compounds
1. A cyclic compound of the formula (I) or a pharmacologically acceptable salt thereof,
wherein X is ═CH— or ═N—, Y is —NH—, —NR 4 —, —S—, —O—, —CH═N—,...
|