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US20120088811 |
METHOD FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA
The invention is in the field of molecular medicine and provides methods for the treatment of acute myeloid leukemia. These methods are based on the observation that microRNA-9 and microRNA-9* are...
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US20110020352 |
ENDOGENOUS RETROVIRUSES UP-REGULATED IN PROSTATE CANCER
Human endogenous retroviruses of the HML-2 family show up-regulated expression in prostate tumors. This finding can be used in prostate cancer screening, diagnosis and therapy.
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US20120204281 |
DRG11-RESPONSIVE (DRAGON) GENE FAMILY
This invention features methods and compositions useful for treating and diagnosing diseases of the nervous system, retina, skin, muscle, joint, and cartilage using a Dragon family protein. Protein...
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US20120204280 |
DRG11-RESPONSIVE (DRAGON) GENE FAMILY
This invention features methods and compositions useful for treating and diagnosing diseases of the nervous system, retina, skin, muscle, joint, and cartilage using a Dragon family protein. Protein...
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US20120178792 |
DRG11-RESPONSIVE (DRAGON) GENE FAMILY
This invention features methods and compositions useful for treating and diagnosing diseases of the nervous system, retina, skin, muscle, joint, and cartilage using a Dragon family protein. Protein...
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US20130036519 |
Compositions and Methods for the Control of Root Lesion Nematode
The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Pratylenchus (root lesion nematodes). The present...
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US20110243942 |
RELAXIN-FUSION PROTEINS WITH EXTENDED IN VIVO HALF-LIVES
Disclosed are human relaxin-Fc fusion proteins having an increased serum half-life, polynucleotides encoding the same, and intermediates formed during the fusion protein biosynthesis. The fusion...
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US20110183421 |
COMPOSITION AND METHOD FOR CONVERTING A NON-PATHOGENIC PRION PROTEIN INTO A PATHOGENIC CONFORMATION AND USES THEREOF
Described herein is a composition for converting a non-pathogenic prion protein (“PrPN”) into a prion protein in a pathogenic conformation (“PrPPath”) comprising a lipid and a polyanion. Also de...
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US20110039719 |
METHODS AND NUCLEIC ACIDS FOR THE ANALYSES OF CELLULAR PROLIFERATIVE DISORDERS
The invention provides methods, nucleic acids and kits for detecting, or for detecting and distinguishing between or among liver cell proliferative disorders or for detecting, or for detecting and...
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US20130061520 |
POD SEALING METHOD
The present invention relates to a method for reducing the seed loss due to pod-shattering using a composition comprising a low viscosity carboxymethyl cellulose and to the use of a low viscosity...
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US20110113989 |
METHYLHYDROXYPROPYLCELLULOSE (MHCP) FOR MINERAL-BOUND BUILDING MATERIAL SYSTEMS
The present invention relates to the preparation of methylhydroxypropylcellulose (MHPC) and the use thereof in mineral-bound building material systems, preferably in gypsum-bound building material...
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US20110195512 |
NOVEL PROTEIN CAPABLE OF BINDING TO HYALURONIC ACID, AND METHOD FOR MEASUREMENT OF HYALURONIC ACID USING THE SAME
The present invention relates to a polynucleotide encoding a protein comprising an amino acid sequence shown in SEQ ID NO: 2, wherein the protein encoded by the polynucleotide has a hyaluronic acid...
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US20110053220 |
NOVEL PROTEIN CAPABLE OF BINDING TO HYALURONIC ACID, AND METHOD FOR MEASUREMENT OF HYALURONIC ACID USING THE SAME
The present invention relates to a polynucleotide encoding a protein comprising an amino acid sequence shown in SEQ ID NO: 2, wherein the protein encoded by the polynucleotide has a hyaluronic acid...
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US20130102482 |
COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF BREAST AND OVARIAN CANCER
The invention relates to newly discovered nucleic acid molecules and proteins associated with breast or ovarian cancer. Compositions, kits, and methods for detecting, characterizing, preventing,...
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US20110092388 |
COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF BREAST CANCER
The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating...
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US20120015827 |
METHOD FOR THERAPY PREDICTION IN TUMORS HAVING IRREGULARITIES IN THE EXPRESSION OF AT LEAST ONE VEGF LIGAND AND/OR AT LEAST ONE ERBB-RECEPTOR
The present invention is related to a method for predicting a clinical response of a patient suffering from or at risk of developing a neoplastic disease towards a given mode of treatment, said...
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US20110318379 |
Vaccine for Porcine Post-Weaning Diarrhea Caused by Enterotoxigenic Escherichia Coli
Vaccines and methods for making and using the same. An example vaccine may be a vaccine against enterotoxigenic Escherichia coli. The vaccine may include an Escherichia coli strain. The Escherichia...
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US20120165228 |
EVOLVING NEW MOLECULAR FUNCTION
Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The present invention provides methods, compositions, and systems for...
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US20130096018 |
METHOD FOR PREDICTING THE SURVIVAL STATUS AND PROGNOSIS OF ESOPHAGEAL CANCER AND A KIT THEREOF
The present invention provides a method for predicting the survival rate and prognosis of esophageal carcinoma patients, which is characterized in examining the expression level of a specific gene,...
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US20120185963 |
Nucleic Acid Molecules and Their Use in Plant Sterility
The present invention provides a method for disrupting pollen development in a plant, the method comprising inhibiting the expression of an endogenous nucleic acid molecule which is, under normal...
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US20120004184 |
TREATMENT OF NUCLEAR FACTOR (ERYTHROID-DERIVED 2)-LIKE 2 (NRF2) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO NRF2
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Nu-clear factor (erythroid-derived 2)-like 2 (NRF2), in particular, by targeting...
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US20100330657 |
Activin receptor-like kinases, proteins having serine threonine kinase domains and their use
A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-β-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may ...
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US20110027284 |
NOGO-A BINDING MOLECULES AND PHARMACEUTICAL USE THEREOF
The present invention provides a binding molecule which is capable of binding to the human NogoA polypeptide or human NiG with a dissociation constant<1000 nM, a polynucleotide encoding such...
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US20110287458 |
METHOD AND COMPOSITION FOR THE DIAGNOSIS AND MONITORING OF INFLAMMATORY DISEASES
The present invention provides a canine S100 calcium binding protein useful in diagnosing an inflammatory disease. Also provided are methods of diagnosing an inflammatory disease by assaying a...
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US20110091976 |
Regulatory region preferentially expressing to seed embryo and method of using same
A Zea mays regulatory region is shown, which provides improved seed preferred, and particularly embryo preferred expression in plants. Methods of use are also shown in preferentially expressing a...
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US20120122955 |
USE OF LNA APOB ANTISENSE OLIGOMERS FOR THE TREATMENT OF ACUTE CORONARY SYNDROMES
The present invention relates to the use of LNA antisense apoB oligonucleotides for the treatment of acute coronary syndrome.
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US20110171637 |
METHODS AND NUCLEIC ACIDS FOR ANALYSES OF CELLULAR PROLIFERATIVE DISORDERS
The invention provides methods, nucleic acids and kits for detecting, or for detecting and distinguishing between or among prostate cell proliferative disorders or for detecting, or for detecting...
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US20110262953 |
Phosphate Limited Inducible Promoter and A Bacillus Expression System
An evolvable production strain of B. subtilis exhibiting continuous or high level expression during protein evolution is described. An evolved Bacillus subtilis pstS promoter facilitates screening...
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US20110046006 |
MEANS AND METHODS FOR TYPING A CELL ISOLATE OF AN INDIVIDUAL SUFFERING FROM A PSYCHIATRIC DISORDER OR AT RISK OF SUFFERING THERE FROM
The present invention relates to a method for typing a cell isolate of an individual suffering from a pychiatric disorder, or at risk for suffering there from, the method comprising providing an...
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US20120142611 |
REPEAT PROTEIN FROM COLLECTION OF REPEAT PROTEINS COMPRISING REPEAT MODULES
A repeat protein from a collection of repeat proteins, wherein each repeat protein of said collection comprises a repeat domain, which comprises a set of consecutive repeat modules, wherein the...
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US20120082983 |
Microbial Reductive Dehalogenation of Vinyl Chloride
Compositions and methods are provided that relate to the bioremediation of chlorinated ethenes, particularly the bioremediation of vinyl chloride by Dehalococcoides-like organisms. An isolated...
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US20130017226 |
TNF-A and TWEAK Dual Antagonist for the Prophylaxis and Treatment of Autoimmune Diseases
The present invention relates to TNFR2-TWEAKR fusion protein, more precisely to TNFR2-TWEAKR fusion protein acting as a double-antagonist to TNF-α and TWEAK, known as major causes of autoimmune ...
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US20130005610 |
TOXICITY-ASSOCIATED GENES, GENETIC VARIANTS, AND USE THEREOF
Genes and genetic variants in human genomes are disclosed which are useful, inter alia, as diagnostic biomarkers.
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US20130071836 |
COLON CANCER BIOMARKER DISCOVERY
The present application discloses an epigenetic marker for colon cancer.
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US20110207656 |
MUC1, CASPASE-8, and DED-CONTAINING PROTEINS
The disclosure features a variety of compositions and methods for modulating an interaction between MUC1 and caspase-8 and/or an interaction between MUC1 and a DED-containing protein (e.g., an...
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US20110160091 |
Methods and Nucleic Acids for Analyses of Cell Proliferative Disorders
The invention provides methods, nucleic acids and kits for determining the prognosis of a subject having cell proliferative disorder, preferably cancer. The invention discloses genomic sequences...
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US20110142947 |
NOVEL FORMULATIONS
Nanoparticles comprising T3 and their use in treating, e.g., cardiac conditions, for example cardiac arrest, are provided. Such nanoparticles provide improved delivery of T3 and allow for acute...
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US20120301494 |
PROTEOLYSIS-RESISTANT CAPSID OF CHIMERIC HEPATITIS E VIRUS AS AN ORAL DELIVERY VECTOR
This invention provides a peptide/nucleic acid composition for oral/mucosal, dual-modal activation of immune protection systems.
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US20110135784 |
BARLEY WITH LOW LEVELS OF HORDEINS
The present invention relates to methods of producing a food or malt-base beverage suitable for consumption by a subject with Coeliac's disease. In particular, the present invention relates to...
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US20120064591 |
RECOMBINANT YEAST WITH IMPROVED ETHANOL TOLERANCE AND RELATED METHODS OF USE
The present invention provides isolated Elo1 and Mig3 nucleic acid sequences capable of conferring increased ethanol tolerance on recombinant yeast and methods of using same in biofuel production,...
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US20120107889 |
ENDOPHYTIC YEAST STRAINS, METHODS FOR ETHANOL AND XYLITOL PRODUCTION, METHODS FOR BIOLOGICAL NITROGEN FIXATION, AND A GENETIC SOURCE FOR IMPROVEMENT OF INDUSTRIAL STRAINS
The present invention provides novel endophytic yeast strains capable of metabolizing both pentose and hexose sugars. Methods of producing ethanol and xylitol using the novel endophytic yeast are...
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US20110190483 |
Stimulus-Responsive Apta Chelamers
Disclosed are apta-chelamers comprising aptamer domains tethered to rationally designed synthetic protein-binding modules, and methods of designing and making the same. Also disclosed are...
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US20110236531 |
GLYCEROGLYCOLIPID LIPASE
Disclosed is a glyceroglycolipid lipase which is highly safe, can hydrolyze a neutral fat, a glycerophospholipid or a glyceroglycolipid at about pH 6, is thermally stable to some extent, can...
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US20130133111 |
COMPOSITIONS AND METHODS OF USE OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE
Methods and compositions for modulating plant response, development and yield under varying environmental conditions are provided. Methods employing MAPKKK are provided. The MAPKKK sequences are...
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US20100306880 |
NUCLEIC ACIDS FOR INDUCING EXPRESSION OF TRANSCRIPTS AND PROTEINS AND METHODS FOR MAKING AND USING THEM
The invention provides nucleic acids and polypeptides for enhanced expression of nucleic acids and proteins. In one aspect, the sequences serve as transcription and translation enhancers or...
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US20120135400 |
Novel Fluorescent and Colored Proteins, and Polynucleotides that Encode These Proteins
The subject invention provides new fluorescent and/or colored proteins, and polynucleotide sequences that encode these proteins. The subject invention further provides materials and methods useful...
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US20120148559 |
COMPOSITIONS AND METHOD FOR DEIMMUNIZATION OF PROTEINS
The invention provides deimmunized mutant proteins having reduced immunogenicity while exhibiting substantially the same or greater biological activity as the proteins of interst from which they...
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US20110159503 |
DNA EXTRACTION METHOD FOR BURSAPHELENCHUS XYLOPHILUS FROM WOOD CHIPS, LAMP PRIMER SET FOR BURSAPHELENCHUS XYLOPHILUS, AND DETECTION METHOD FOR BURSAPHELENCHUS XYLOPHILUS FROM WOOD CHIPS
To extract and detect Bursaphelenchus xylophilus DNA without isolating Bursaphelenchus xylophilus from a piece of wood taken from a tree belonging to the genus Pinus and the like, provided are a...
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US20110003333 |
Method for Increasing Expression Yield of a Protein of Interest
The present invention relates to a method of producing a protein of interest comprising: (a) cultivating a mutant cell under conditions conducive for production of the protein wherein the mutant...
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US20130078274 |
LIVE, ORAL VACCINE FOR PROTECTION AGAINST SHIGELLA DYSENTERIAE SEROTYPE 1
The invention relates to Salmonella typhi Ty21a comprising core-linked Shigella dysenteriae serotype 1 O-specific polysaccharide (O-Ps) and DNA encoding O antigen biosynthesis, said DNA selected...
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