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US20140288283 TRUNCATED L1 PROTEIN OF HUMAN PAPILLOMAVIRUS TYPE 6  
The invention relates to a truncated L1 protein of the Human Papillomavirus Type 6, a virus-like particle consisting of the protein, a vaccine comprising said virus-like particle, and the use of...
US20120165268 P53 FUSION PROTEINS AND METHODS OF MAKING AND USING THEREOF  
Biologically active tetrameric p53 proteins and p53 fusion proteins are provided. These proteins may be generated and refolded into tetrameric form using denatured proteins produced from E. coli....
US20130315943 TRUNCATED L1 PROTEIN OF HUMAN PAPILLOMAVIRUS TYPE 58  
Provided are an N-terminal truncated L1 protein of the Human Papillomavirus Type 58, a coding sequence and preparation method thereof, and a virus-like particle comprising the protein. Uses of the...
US20120016113 BUOYANT PROTEIN HARVESTING DEVICE  
A buoyant device containing chromatography media performs the function of protein harvesting replacing the steps of cell separation and volume reduction; the device can be loaded into columns for...
US20130012684 Purification Method  
The present invention provides a method for purification of a protein that is conjugated to an albumin binding moiety from a mixture comprising (i) said protein in said conjugated form and (ii)...
US20130338344 PROTEIN PURIFICATION METHODS TO REDUCE ACIDIC SPECIES  
The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and...
US20140162248 Use of Aptamers in Liquid Chromatography and Liquid Chromatography - Mass Spectrometry  
The present disclosure relates to the use of aptamers in solid phase extraction, chromatography and chromatography-mass spectrometry systems. More specifically, the present disclosure relates to...
US20110150911 Methods and reagents for treating, preventing and diagnosing bunyavirus infection  
Immunogenic compositions for use in treating, preventing and diagnosing infection caused by the California (CAL) serotype of the genus Bunyavirus, such as La Crosse virus (LACV), are disclosed....
US20130172535 PROCESS FOR PROTEIN EXTRACTION  
The invention includes a process for extracting a target protein from E. coli cells that includes lowering the pH of a whole E. coli cell solution to form an acidic solution, disrupting the cells...
US20110065897 METHOD FOR ISOLATING POLYPEPTIDES  
The present invention relates to a method for isolating and/or purifying at least one polypeptide from a polypeptide-containing sample, characterized in that the sample is contacted with a boron...
US20110120947 HYDROPHOBIC CELLULOSE MEMBRANE, METHOD FOR THE PRODUCTION THEREOF, AND USE OF SAME IN HYDROPHOBIC INTERACTION CHROMATOGRAPHY  
There is provided a crosslinked cellulose hydrate membrane having a porous double structure which consists of micropores having a diameter in the range from >100 nm to 20 μm and ultrapores which...
US20130253142 SEPARATING AGENT FOR PROTEIN PURIFICATION AND PROTEIN PURIFICATION METHOD  
A novel separating agent for protein purification which not only can adsorb proteins in a sufficient amount for protein purification from a low concentration buffer but also can desorb the...
US20150105542 METHOD AND SYSTEM FOR POLYPEPTIDE PURIFICATION  
The present invention provides a method and automated system for the purification of polypeptides including the direct filtration of solutions containing the polypeptides after purification.
US20120253024 METHOD AND SYSTEM FOR POLYPEPTIDE PURIFICATION  
The present invention provides a method and automated system for the purification of polypeptides including the direct filtration of solutions containing the polypeptides after purification.
US20090145203 PLUGGED FLOW 2D CHROMATOGRAPHY  
The invention provided is a split-free nano-liter flow liquid chromatography system comprising at least a first and a second chromatographic column connected in series, wherein an autosampler is...
US20150125929 USE OF CHARGED FLUOROCARBON COMPOSITIONS IN METHODS FOR PURIFICATION OF BIOMOLECULES  
The present invention relates to novel and improved methods for the purification of biomolecules. In particular, the present invention relates to methods of protein purification which employ a...
US20120271042 METHOD FOR ISOLATION OF GENOMIC DNA, RNA AND PROTEINS FROM A SINGLE SAMPLE  
The invention provides systems, methods and kits for the separation and/or purification of at least two cellular components selected from genomic DNA, RNA and proteins. The method includes first...
US20110301333 REMOVAL OF PROTEIN AGGREGATES FROM BIOPHARMACEUTICAL PREPARATIONS USING CALCIUM PHOSPHATE SALTS  
The present invention provides novel and improved compositions containing calcium phosphate and methods of using the same for the removal of protein aggregates from biopharmaceutical compositions...
US20120122076 PURIFICATION OF ANTIBODIES USING SIMULATED MOVING BED CHROMATOGRAPHY  
The present invention relates to compositions and methods for the chromatographic purification of antibodies, such as monoclonal antibodies, employing improved simulated moving bed separation...
US20130096284 METHOD FOR PURIFYING PROTEIN USING AMINO ACID  
In large-scale purification of proteins such as antibodies, an economic high-purity purification method is required. The present invention relates to a method for purifying a protein, including...
US20070253965 Reagents for Diagnosis and Therapy of Latex Allergy and Method for the Preparation of the Same  
The present invention relates to reagents for diagnosis and/or therapy of latex allergy or fruit allergy and to a method for the preparation of the reagents.
US20080167452 Process for Purification of Human Growth Hormone  
Adding enough organic solvent to hydrophobic interactive chromatography elution buffer eliminates the need to also add detergent to the buffer when separating poly-peptides. For example, adding...
US20080070832 Method for Purifying Fsh  
The invention relates to a method for purifying recombinant human FSH or an FSH variant starting from crude FSH, comprising the following steps: 1. dye-affinity chromatography; 2. hydrophobic...
US20080015341 New hydrophobic polymer comprising fluorine moieties  
A composite material having a support which is at least partially covered by a hydrophobic polymer comprising fluorine moieties obtainable by a process comprising the steps of contacting the...
US20120177610 Manufacturing and Purification Processes of Complex Protein found in Fraction IV to make a separated Apo, Transferrin , and Alpha 1 Anti strepsin (A1AT) or A combined Transferrin / Apo/Human Albumin/A1AT and all new found proteins  
Manufacturing and Purification Processes of Complex Protein found in Fraction IV to make a separated Apo, Transferrin, and Alpha 1 Antitrypsin (A1AT) or a combined Transferrin/Apo/Human...
US20120039920 HYDROPHOBIC MONOMERS, HYDROPHOBICALLY-DERIVATIZED SUPPORTS, AND METHODS OF MAKING AND USING THE SAME  
A composition is disclosed comprising a hydrophobic monomer having the structure: CH2═CR4C(O)NHC(R1R1)(C(R1R1))nC(O)XR3 wherein n is an integer of 0 or 1; R1 is independently selected from at...
US20100261886 PROTEIN PURIFICATION BY CITRATE PRECIPITATION  
The invention provides methods for isolating proteins in purified form from mixtures by precipitation with citrate. The methods are advantageous in that they effectively separate a protein from...
US20120264920 PROCESSES FOR PURIFICATION OF PROTEINS  
The invention is directed to a method for purifying a protein. The method involves providing a sample containing the protein, processing the sample through a capture chromatography resin,...
US20050090652 Highly homogenous serum albumin as chiral selector  
The present invention provides the use of highly homogeneous serum albumin as a chiral selector, preferably immobilised, such as in enantioselective chromatography. The present invention also...
US20140065672 SEPARATOME-BASED PROTEIN EXPRESSION AND PURIFICATION PLATFORM  
Provided is a separatome-based recombinant peptide, polypeptide, and protein expression and purification platform based on the juxtaposition of the binding properties of host cell genomic...
US20110263834 Simple Method for Simultaneous Removal of Multiple Impurities from Culture Supernatants to Ultralow Levels  
This invention is directed to methods for removing, preferably simultaneously and in one step, multiple impurities form crude culture samples, and, in particular, the removal of media components,...
US20080176789 Purification of Factor Xlll Polypeptides From Biological Materials  
The invention relates to a method for purifying a factor XIII polypeptide from a biological material, the method comprising subjecting the material to sequential chromatography on an...
US20150165343 MULTIDIMENSIONAL LIQUID CHROMATOGRAPHY SEPARATION SYSTEM AND SEPARATION METHOD FOR PROTEIN SEPARATION  
A multidimensional liquid chromatography separation system has a mobile-phase storage tank, a first liquid transfer device, a second liquid transfer device, a first sample introduction device, a...
US20140220633 PURIFICATION OF NOT-GLYCOSYLATED POLYPEPTIDES  
The current invention reports a method for the purification of a not-glycosylated, heterologous polypeptide, which has been recombinantly produced in a prokaryotic cell, wherein the method...
US20130190478 PURIFICATION OF NOT-GLYCOSYLATED POLYPEPTIDES  
The current invention reports a method for the purification of a non-glycosylated, heterologous polypeptide, which has been recombinantly produced in a prokaryotic cell, wherein the method...
US20120232255 PRETREATMENT CARTRIDGE FOR SEPARATING SUBSTANCE AND METHOD OF PRETREATMENT USING THE SAME  
Pretreatment is performed using a pretreatment cartridge for separating substances that is packed with a stationary phase that is coated on its surface with a polymer whose tendency to hydration...
US20140288272 ANTIBODY PURIFICATION AND PURITY MONITORING  
Processes for producing and purifying recombinant proteins are disclosed. In particular, the present disclosure provides processes of producing and purifying multi-subunit proteins expressed in...
US20100311953 PROCESS FOR PURIFYING PROTEINS  
The invention relates to a process for purifying a protein by mixing a protein preparation with a solution having a first salt and a second salt, wherein each salt has a different lyotropic value,...
US20120022228 PURIFICATION OF AMPHOTERIC PRODUCTS, OR OF PRODUCTS LIABLE TO BE CONVERTED INTO AMPHOTERIC PRODUCTS  
A process for purifying at least one product from a substrate containing at least one product, includes subjecting the substrate to centrifugal partition chromatography in an ion exchange...
US20150184215 DEVELOPMENT OF THE SOLUBLE RECOMBINANT CRM197 PRODUCTION BY E. COLI  
A method for recombinant production of a CRM197 protein includes culturing a recombinant Escherichia coli cell to produce said CRM197 protein, and isolating said CRM197 protein. The recombinant...
US20070244307 Chromatography Ligand  
The present invention relates to a chromatography ligand defined by the following formula (I) R1—R2—N(R3)—R4—R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon...
US20150203531 Sterile Chromatography Resin and Use Thereof in Manufacturing Processes  
Provided herein are methods of reducing bioburden of (e.g., sterilizing) a chromatography resin that include exposing a container including a composition including a chromatography resin and at...
US20150202595 Sterile Chromatography Resin and Use Thereof in Manufacturing Processes  
Provided herein are methods of reducing bioburden of (e.g., sterilizing) a chromatography resin that include exposing a container including a composition including a chromatography resin and at...
US20090117103 M-CSF Antibody compositions Having Reduced Levels of Endotoxin  
The present invention provides for compositions of anti-M-CSF antibodies that are substantially free of endotoxin. Also provided are methods of treating M-CSF-mediated disorders with...
US20150065696 APPARATUS AND PROCESS FOR PURIFICATION OF PROTEINS  
The invention is directed to an apparatus and method for purifying a protein. The apparatus involves the use of a capture chromatography resin, a depth filter arranged after the capture...
US20110301342 APPARATUS AND PROCESS FOR PURIFICATION OF PROTEINS  
The invention is directed to an apparatus and method for purifying a protein. The apparatus involves the use of a capture chromatography resin, a depth filter arranged after the capture...
US20050070696 Production process of recombinant placental growth factor  
Process for extracting and purifying the recombinant Placental Growth Factor (PLGF) expressed in inducible prokaryotic expression systems comprising the following steps: I) fermentation of the...
US20070249529 Compositions Comprising Polypeptides  
The present invention relates to compositions comprising polypeptides, especially polypeptides capable of specifically binding predetermined antigens. The polypeptide in the composition comprises...
US20100113751 PURIFICATION OF ACIDIC PROTEINS USING CERAMIC HYDROXYAPATITE CHROMATOGRAPHY  
The present invention provides a method of removing product-related inactive or partially active species, high molecular weight aggregates, as well as other process-related impurities from...
US20120029176 Chromatography Media And Method  
Adsorptive media for chromatography, particularly ion-exchange chromatography, derived from a shaped fiber. In certain embodiments, the functionalized shaped fiber presents a fibrillated or ridged...

Matches 1 - 50 out of 99 1 2 >