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US20090288230 |
Novel Efficient Transformation Method for Sunflower and Oil Seeds Based On Positive Selection
The invention describes a highly improved, reproducible and a consistent method of transformation and regeneration that results in obtaining 12-15% transgenic plants. The present invention relates...
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US20090288225 |
Novel Aromatic Acyltransferase Genes
The present invention provides a protein having the amino acid sequence as shown in SEQ ID NO: 2, 4, 6, 8, 10 or 12 or a protein having a modified amino acid sequence thereof and having an activity...
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US20090286957 |
NOVEL NUCLEOTIDE AND AMINO ACID SEQUENCES, AND ASSAYS AND METHODS OF USE THEREOF FOR DIAGNOSIS OF BREAST CANCER
Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these...
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US20090286956 |
DELTA3, FTHMA-070, TANGO85, TANGO77, SPOIL, NEOKINE, TANGO129, and INTEGRIN ALPHA SUBUNIT Protein and nucleic acid molecules and uses thereof
The invention provides novel Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 polypeptides, proteins, and nucleic acid molecules. In addition to isolated, full-length Delta3,...
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US20090286721 |
TARGETED PLASMINOGEN ACTIVATOR FUSION PROTEINS AS THROMOBOLYTIC AGENTS
This invention relates to novel fusion proteins, comprising a targeting protein and a plasminogen activator, preferably an antibody that binds to P-selectin, operably linked to the plasminogen...
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US20090286314 |
Fluorescent proteins and genes encoding them
Fluorescent proteins comprising the following internal amino acid sequence
(SEQ ID NO: 47) Gly Tyr Xaa Xaa Xaa Gln Tyr Leu Pro Xaa Pro 1 5 10
wherein
...
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US20090286293 |
ETHANOL PRODUCTION IN NON-RECOMBINANT HOSTS
Non-recombinant bacteria that produce ethanol as the primary fermentation product, associated nucleic acids and polypeptides, methods for producing ethanol using the bacteria, and kits are disclosed.
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US20090286279 |
Genetically programmed expression of selectively sulfated proteins in eubacteria
The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the unnatural amino acid sulfotyrosine into proteins produced in eubacterial host cells such...
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US20090286273 |
USE OF NEUREGULIN-BETA AS AN INDICATOR AND/OR TARGET
The invention relates, inter alia, to the use of neuregulin-β as a target in a screening method for active compounds, in particular for exerting an influence on changes in calcium concentration...
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US20090286262 |
NUCLEIC ACID, POLYPEPTIDE AND ITS USE
Novel chimeric proteins functional to screen for sweet taste modulators, the corresponding nucleic acid sequences, expression vectors, transfected host cells, and screening methods for modulators...
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US20090286259 |
SCREENING METHOD FOR GPCR LIGANDS
This invention relates to a method of identifying a compound capable of binding to a target domain of a G-protein coupled receptor comprising the steps of: (a) providing a receptor comprising said...
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US20090286252 |
NRIF3, NOVEL CO-ACTIVATOR FOR NUCLEAR HORMONE RECEPTORS
Nucleic acids encoding NRIF3 are described. Polypeptides having amino acid sequences of NRIF3 proteins are also provided. A method is also provided for isolating and cloning NRIF3 cDNA. NRIF3 is...
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US20090286230 |
Methods, Devices, Kits and Compositions for Detecting Roundworm
Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present...
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US20090286229 |
Methods, Devices, Kits and Compositions for Detecting Roundworm
Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present...
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US20090286228 |
Methods, Devices, Kits and Compositions for Detecting Roundworm
Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present...
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US20090286227 |
Methods, Devices, Kits and Compositions for Detecting Whipworm
Methods, devices, kits and compositions for detecting the presence or absence of whipworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present...
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US20090285857 |
RECOMBINANT CHIMERIC ANTIGENS FOR DIAGNOSIS AND PREVENTION OF SCRUB TYPHUS
Recombinant chimeric antigens comprising unmodified and modified reactive polypeptide fragments of expressed product of the recombinant 56 kDa proteins of multiple strain of scrub typhus, such as...
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US20090285853 |
Nucleic Acids Encoding Respiratory Syncytial Virus Subgroup B strain 9320
The complete polynucleotide sequence of the human respiratory syncytial virus subgroup B strain 9320 genome is provided. Proteins encoded by this polynucleotide sequence are also provided. Isolated...
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US20090285846 |
MUTANTS OF CHOLESTEROL-DEPENDENT CYTOLYSINS AND USES THEREOF
Mutants of cholesterol-dependent cytolysins comprising at least one amino acid substitution in at least one of Loop 1, Loop 2, or Loop 3 of Domain 4, nucleic acids encoding such polypeptide...
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US20090285845 |
Domains And Epitopes Of Meningococcal Protein NMB1870
‘NMB1870’ is a known surface protein in Neisseria meningitidis expressed across all serogroups. It has three distinct families. Serum raised against a given family is bactericidal within the...
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US20090285825 |
NOVEL SNAKE TOXIN
This invention is in the field of snake venom and the invention provides a novel snake toxin protein and nucleic acids encoding the same. Also, provided are various uses and compositions based on...
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US20090285801 |
Calcium-Sensing Receptor 2 (CaR2) and Methods for Using
The current disclosure provide a novel human calcium sensing receptor named CaR2 and the nucleotide sequence that encodes the receptor. The disclosure further provides antibodies specific for CaR2....
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US20090285796 |
MUTANT JAK3 KINASE IN HUMAN LEUKEMIA
In accordance with the invention, a novel activating mutation (alanine 572 to valine) in JAK3 kinase has been discovered in human acute myelogenous leukemia (AML). The mutant JAK3 kinase was...
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US20090285785 |
External Agent for Treatment of Skin Ulcer
[Problems] To provide a novel external agent for treatment of skin ulcer which has an excellent healing effect on intractable skin ulcer such as bedsore, diabetic skin ulcer and ischemic skin...
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US20090285783 |
Methods and compositions for cancer therapy using a novel adenovirus
The invention comprises a novel virus that can kill mammalian cancer cells efficiently. The virus produces a novel protein that converts two non-toxic prodrugs into potent chemotherapeutic agents....
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US20090282495 |
NEUROTROPHIC FACTOR MANF AND USES THEREOF
The present invention generally relates to the field of treatment of neuronal disorders and more particularly to neurotrophic factor MANF and uses thereof. The present invention provides a...
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US20090281287 |
IL-17 receptor like molecules and uses thereof
The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists...
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US20090281277 |
PEPTIDES CAPABLE OF BINDING TO SERUM PROTEINS AND COMPOUNDS, CONSTRUCTS AND POLYPEPTIDES COMPRISING THE SAME
The present invention relates to amino acid sequences that are capable of binding to serum proteins; to compounds, proteins, polypeptides, fusion proteins or constructs comprising or essentially...
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US20090281036 |
FUSION PEPTIDE FOR INHIBITING INTERACTION OF NEURONAL NMDA RECEPTOR (NMDAR) AND NMDAR INTERACTING PROTEINS
The present invention provides a fusion peptide comprising at least a component (I), wherein component (I) comprises a transporter peptide, and a component (II), selected from a peptide inhibiting...
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US20090281035 |
Soluble Heterodimeric Receptors and Uses Thereof
Soluble versions of heterodimeric receptors, e.g., CD94/NKG2 receptors, and methods of producing and using such constructs, are described. The constructs comprise soluble fragments of, each...
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US20090281031 |
Methods and Compositions Related to Improving Properties of Pharmacological Agents Targeting Nervous System
Disclosed are compositions and methods related to improving pharmacological properties of bioactive compounds targeting nervous system.
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US20090281024 |
Compositions Comprising Receptor-Associated Protein (RAP) Variants Specific for CR-Containing Proteins and Uses Thereof
The present invention relates generally to receptor-selective variants of the low-density lipoprotein receptor-associated protein (RAP) and compositions thereof, methods of generating such variants...
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US20090280512 |
TUMOR MARKER FOR RENAL CANCER AND METHOD FOR DETERMINATION OF OCCURRENCE OF RENAL CANCER
The present invention provides a tumor marker more highly specific to renal cancer. The present invention provides a method for identifying the morbidity of renal cancer. A tumor marker for renal...
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US20090280488 |
Prophylactic/therapeutic agent for neurodegenerative disease
To provide a prophylactic/therapeutic agent for neurodegenerative diseases (such as polyglutamine diseases), the agent containing an HMGB family protein or a derivative thereof, such as a protein...
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US20090280482 |
Novel nucleic acid sequences encoding adenylate kinases, alcohol dehydrogenases, ubiquitin proteases, lipases, adenylate cyclases, and GTPase activators
The invention provides isolated nucleic acids molecules that encode novel polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing the...
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US20090280480 |
Devices from Prion-Like Proteins
The present invention provides novel polypeptides comprising a prion-aggregation domain and a second domain; novel polynucleotides encoding such polypeptides; host cells transformed or transfected...
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US20090280168 |
CHLAMYDIA OMP ANTIGEN
The present invention provides purified and isolated polynucleotide molecules that encode Chlamydia polypeptides which can be used in methods to prevent, treat, and diagnose Chlamydia ...
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US20090280141 |
Streptococcal Genes
Peptides derived from S. pneumoniae are identified as virulence determinants and may be useful in the preparation of vaccines for the treatment of infection. The peptides may be used as antigens...
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US20090280125 |
Prion epitopes and methods of use thereof
Prion peptides comprising prion epitopes and fusions thereof, that display enhanced immunogenicity are described. Also described are methods of treating and diagnosing prion disease.
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US20090280110 |
Cell Model for Alzheimer's Disease Pathology
The present invention encompasses compositions and methods for studying in cell culture the pathologic changes associated with Alzheimer's disease. The present invention further relates to methods...
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US20090280092 |
G-Protein Coupled Receptor 83 As a Molecular Switch for the Induction of Regulatory (immunosuppressive) T-cells
The present invention makes use of the role of the G-protein coupled receptor 83 (GPCR83) in the induction of regulatory T cells (Tregs) during the course of ongoing immune response. The present...
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US20090280085 |
Long Acting Human Interferon Analogs
Compositions, kits and methods are provided for Interferon analogs in order to promote general health or for therapeutic treatment of diseases. Human interferon analogs are made by fusion of...
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US20090276863 |
Protein formulations comprising s1-5
The present inventors discovered that knockout mice whose S1-5 gene function is lost develop age-related diseases or symptoms. Histological analysis in such knockout mice revealed that bone mineral...
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US20090276160 |
CRYSTAL STRUCTURE OF HEPATOCYTE GROWTH FACTOR ACTIVATOR COMPLEXED WITH KUNITZ DOMAIN INHIBITOR
The present disclosure provides crystals of and structural coordinates of Hepatocyte growth factor activator with and without bound pseudo-substrate or inhibitor. In a specific embodiment, a...
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US20090275738 |
Use of A33 antigens and jam-it
The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer.
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US20090275649 |
Compositions And Methods For Identifying Modulars Of TRPV2
It has now been discovered that certain cannabinoids specifically activate TRPV2 channel activity. Based on the discovery, novel compositions and methods for screening, identifying and...
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US20090275636 |
PICORNAVIRUS AND USES THEREOF
The invention is directed to a a clade of newly isolated and identified picornaviruses associated with respiratory infection, and isolated nucleic acids sequences and peptides thereof. The...
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US20090275521 |
Regulation of Microphage Migration Inhibitory Factor (MIF) Activity
The present invention relates to modulating, neutralizing, or inactivating the activity of migration inhibitory factor (MIF). In particularm, the present invention provides methods for modulating,...
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US20090275517 |
G-CSF POLYPEPTIDES AND USES THEREOF
The present invention relates to G-CSF polypeptides and their uses, particularly for therapeutic or prophylactic treatment in human subjects. The invention also relates to nucleic acids encoding...
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US20090275510 |
Compositions and Methods for Inducing or Inhibiting Activities of Selected Human Cells
Polynucleotides encoding a mutant human carboxylesterase enzyme and polypeptides encoded by the polynucleotides which are capable of metabolizing a prodrug and inactive metabolites thereof to...
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