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US20150185232 INNATE IMMUNE PROTEINS AS BIOMARKERS FOR CNS INJURY  
The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein...
US20100305227 Protein-Containing Foams, Manufacture and Use Thereof  
The invention relates generally to protein-containing polyurethane foams, methods and compositions for making the polyurethane foams, and articles comprising the polyurethane foams.
US20140256633 Relaxin Proteins For Use In The Diagnosis, Prevention or Treatment of Multiple Sclerosis  
The present invention relates to the use of one or more Relaxin proteins in methods for diagnoses and treatment of multiple sclerosis. The invention also provides compositions for use in...
US20120046369 Methods for enhancing the stability of foods, beverages, and cosmetics using natural products derived from non-allergenic proteinaceous sources  
The present invention relates to compositions with effective metal chelating activity and utility as natural antioxidants in food, beverages, nutritional supplements and cosmetics. The...
US20110112037 CRYSTAL STRUCTURE  
The invention provides a method of predicting a three dimensional structural representation of a target protein of unknown structure, or part thereof, comprising: providing the coordinates of the...
US20110207213 Photoreactive Synthetic Regulator of Protein Function and Methods of Use Thereof  
The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic...
US20110183855 SOMATIC HYPERMUTATION SYSTEMS  
The present application relates to somatic hypermutation (SHM) systems and synthetic genes. Synthetic genes can be designed using computer-based approaches to increase or decrease susceptibility...
US20140187741 MEANS AND METHODS FOR MEDIATING PROTEIN INTERFERENCE  
The present invention belongs to the field of functional proteomics and more particularly to the field of protein aggregation. The invention discloses a method for interfering with the function of...
US20110070268 Method  
Methods for characterisation of patients as responders or non-responders to therapy based on differential expression of one or more genes are provided. Gene expression profiles, microarrays...
US20130209499 VACCINES FOR USE IN THE PROPHYLAXIS AND TREATMENT OF INFLUENZA VIRUS DISEASE  
Provided herein are polypeptides comprising portions of the influenza virus hemagglutinin, compositions comprising such polypeptides that can be used as immunogens in vaccines and methods of their...
US20100310877 Protein-Containing Emulsions and Adhesives, and Manufacture and Use Thereof  
This invention provides emulsions and adhesives comprising proteins that can be isolated from a variety of sources including renewable plant biomass, and methods of making and using such emulsions...
US20130156702 METHODS FOR THE TREATMENT AND THE DIAGNOSIS OF CANCER  
The present invention relates to methods for the diagnostic and the staging of cancer such as liver cancer. The present invention also relates to methods for the treatment of cancer including...
US20120100116 NEURON GENERATION, REGENERATION AND PROTECTION  
The invention demonstrates that, contrary to apoptotic rabies virus G proteins, certain non-apoptotic rabies virus G proteins, such as the G protein of the CVS-NIV strain, have a neurite outgrowth...
US20130203959 NONNATURAL COLLAGEN-LIKE PROTEIN AND USE THEREOF  
This present invention relates to compositions comprising biological active proteins fused with extended recombinant gelatin-like protein (GLK), nucleic acids encoding the compositions and vectors...
US20150141321 COMPOUND AND METHOD FOR TREATING MYOTONIC DYSTROPHY  
Provided are 9-base morpholino antisense compounds targeted to polyCUG repeats in the 3′UTR region of dystrophia myotonica protein kinase (DMPK) mRNA, and related methods for treating myotonic...
US20140107013 COMPOUND AND METHOD FOR TREATING MYOTONIC DYSTROPHY  
Provided are 9-base morpholino antisense compounds targeted to polyCUG repeats in the 3′UTR region of dystrophia myotonica protein kinase (DMPK) mRNA, and related methods for treating myotonic...
US20110269665 COMPOUND AND METHOD FOR TREATING MYOTONIC DYSTROPHY  
Provided are 9-base morpholino antisense compounds targeted to polyCUG repeats in the 3′UTR region of dystrophia myotonica protein kinase (DMPK) mRNA, and related methods for treating myotonic...
US20130022555 METHODS AND MATERIALS FOR PROVIDING TEETH WITH A WHITE APPEARANCE  
This document provides methods and materials for providing teeth with a white appearance. For example, methods and materials for contacting teeth with one or more fluorescence emitting...
US20110059851 SHOC2 Mutations Causing Noonan-Like Syndrome With Loose Anagen Hair  
The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is...
US20120053509 VACCINES FOR HUMAN PAPILLOMA VIRUS AND METHODS FOR USING THE SAME  
Improved anti-HPV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HPV 6, HPV 11, HPV 33 and HPV58 E6 and E7....
US20110172153 SCREENING METHODS USING G-PROTEIN COUPLED RECEPTORS AND RELATED COMPOSITIONS  
The present invention provides screening methods for GPCRs based on the discovery that the affinity of a receptor agonist for a GPCR (such as the parathyroid hormone receptor) when not bound to a...
US20120165228 EVOLVING NEW MOLECULAR FUNCTION  
Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The present invention provides methods, compositions, and systems for...
US20130189243 BIOMARKERS FOR ACUTE ISCHEMIC STROKE  
The present invention provides methods and compositions for the diagnosis of acute ischemic stroke. The invention further provides methods and compositions for distinguishing acute ischemic stroke...
US20110207656 MUC1, CASPASE-8, and DED-CONTAINING PROTEINS  
The disclosure features a variety of compositions and methods for modulating an interaction between MUC1 and caspase-8 and/or an interaction between MUC1 and a DED-containing protein (e.g., an...
US20110207124 Genetic Alterations Associated with Autism and the Autistic Phenotype and Methods of Use Thereof for the Diagnosis and Treatment of Autism  
Compositions and methods for the detection and treatment of autism and autistic spectrum disorder are provided.
US20120010557 Drug Delivery System for Use in the Treatment of Vascular and Vessel-Related Pathologies  
The present invention relates to a drug delivery system for use in the treatment of vascular and vessel-related pathologies, comprising a drug delivery platform that comprises at least one...
US20110126312 METHOD FOR IMPROVING SALINITY TOLERANCE  
The invention relates to a specific method for improving the tolerance to salinity of living organisms and eliminating sodium (Na+) from water, soil, sludge or any other medium containing said...
US20130171069 NEUROTOXIC TARGET FOR AMYLOSPHEROID, METHOD AND MATERIAL FOR REDUCING THE NEUROTOXICITY OF AMYLOSPHEROID, AND USE THEREOF  
In one or a plurality of embodiments, there is provided a target molecule of amylospheroid, which is expressed in mature neurons and to which the amylospheroid binds to induce death of cells....
US20110224143 NUCLEOBINDIN I VARIANT PROTEIN COMPOSITIONS AND METHODS OF USE  
The invention relates to Nucleobindin-1 (NUCB1) protein variants that are capable of disaggregating amyloid fibrils as well as inhibiting the formation of fibrils in the presence of physiological...
US20140329706 AFFINITY TAGS, AND RELATED AFFINITY LIGANDS, ENGINEERED PROTEINS, MODIFIED SUPPORTS, COMPOSITIONS, METHODS AND SYSTEMS  
Affinity tags and ligands comprising a PDZ domain peptide and a PDZ binding carboxy terminal peptide and related engineered protein, engineered labels, compositions, methods and systems.
US20110195074 Ephrin Type-A Receptor 7 Protein  
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of bladder cancer, breast cancer, colorectal cancer, gastric cancer, head and neck cancer,...
US20120121537 Methods and Compositions for Inhibiting Hepatitis C Virus Replication  
Compositions and methods for reducing hepatitis C virus (HCV) replication are provided. Also provided are compositions and methods of treating an HCV infection; methods of reducing the incidence...
US20120328894 NON-COVALENTLY BONDING ANTI-MICROBIAL NANOPARTICLES FOR WATER SOLUBLE WOOD TREATMENT  
Embodiments described herein include capped nanoparticles having a nanoparticle core and at least one capping agent including a biochemical constituent of wood or a woody plant or a derivative...
US20120027742 METHODS FOR TREATING ADULT RESPIRATORY DISTRESS SYNDROME  
We have discovered that the activated phosphorylated form of focal adhesion kinase (hereafter “FAKp”) strengthens the microvascular endothelial cell (EC) junctions that form a barrier in pulmonary...
US20120164229 DEPOT SYSTEMS COMPRISING GLATIRAMER OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF  
The present invention provides long acting parenteral pharmaceutical compositions comprising a therapeutically effective amount of glatiramer. In particular, the present invention provides a long...
US20110305718 Recombinant Protein Body-Inducing Polypeptides  
Polypeptide sequences for inducing recombinant protein bodies are described. The sequences comprise a polyproline II (PPII) structure and/or a proline-rich sequence between two cysteine residues...
US20130041307 APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT  
The present invention provides methods to obtain biologically active compounds that can be used as photosensitizers for diagnostic and therapeutic applications, particularly for PDT of cancer,...
US20110269687 IFBM'S TO PROMOTE THE SPECIFIC ATTACHMENT OF TARGET ANALYTES TO THE SURFACE OF ORTHOPEDIC IMPLANTS  
The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding...
US20110197315 ISOLATED POLYNUCLEOTIDES AND POLYPEPTIDES AND METHODS OF USING SAME FOR INCREASING PLANT YIELD  
Provided are methods of increasing yield, biomass, growth rate, vigor, oil content, abiotic stress tolerance and/or nitrogen use efficiency of a plant by expressing within the plant an exogenous...
US20140134184 PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11 (PTPN11) AND TRIPLE-NEGATIVE BREAST CANCER  
The present invention relates to a method for treating breast cancer in a subject having a breast cancer of the triple-negative type, which method comprises the step of administering to said...
US20100056754 NANO-PUMP USING MOLECULAR MOTOR  
Nano-pumps including nano-motors that move dynamically in response to exterior stimuli, for example in response to photonic energy, electrical energy, a magnetic field, and/or a chemical...
US20110218150 ANTIANGIOGENIC POLYPEPTIDES AND METHODS FOR INHIBITING ANGIOGENESIS  
Conjugated kringle protein fragments are disclosed as compounds for treating angiogenic diseases. Methods and compositions for inhibiting angiogenic diseases are also disclosed.
US20140343225 HYDROGELS AND METHODS FOR PRODUCING AND USING THE SAME  
The present invention relates to hydrogels and methods for producing and using the same. In particular, some embodiments of the invention relate to hydrogels and methods for patterning the same.
US20120190098 FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS  
Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived...
US20120296067 COMPOUND CAPABLE OF BINDING TO NATURALLY OCCURRING DENATURED PROTEIN, AND METHOD FOR SCREENING FOR THE COMPOUND  
Screening for low molecular weight compounds that regulate protein-protein interactions of a large number of proteins, including transcription factors, that have disordered sequences has been...
US20140213511 COMPOSITIONS AND METHODS OF USE FOR TREATING METABOLIC DISORDERS  
Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
US20110256172 EPITOPE-TARGETED ANTHRAX VACCINE  
Anthrax vaccine compositions comprise a segment of a PA toxin protein that stimulates a B cell immune response specific for a defined epitope on the protective antigen of B. anthracis, a...
US20120196307 SYNAPTOTAGMIN AND COLLAPSIN RESPONSE MEDIATOR PROTEIN AS BIOMARKERS FOR TRAUMATIC BRAIN INJURY  
Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological samples after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2,...
US20110030077 METHODS OF MODULATING THE ORGANIC SOLUTE AND STEROID TRANSPORTER (OSTalpha-OSTbeta) ACTIVITY AND TREATING ASSOCIATED CONDITIONS  
The present invention is directed to methods of modulating bile acid and lipid transport via the organic solute and steroid transporter Ostα-Ostβ. The present invention is further directed to...
US20120040377 RECOGNITION OF CYP2E1 EPITOPES  
A critical epitope of human cytochrome P4502E1 (CYP2E1) associated with the development of hepatic autoimmune disease, including methods and kits for diagnosis and prognosis using the critical...