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US20130337076 PARTICLES CONTAINING A GROWTH FACTOR, AND USES THEREOF  
The present invention concerns particles containing at least one covalently cross-linked polysaccharide and at least one growth factor, a method of preparation, and uses thereof.
US20060189519 Anti-angiogenic fragments fo pigment epithelium-derived factor (pedf)  
The present invention provides anti-angiogenic derived from pigment epithelium-derived factor (PEDF) pharmaceutical compositions comprising the peptides, and methods of preventing angiogenesis....
US20050180957 Method of using fibrin-bound angiogenic factors to stimulate vascularization of transplant site of encapsulated cells  
The present invention relates to compositions and methods of treating a disease, such as diabetes, by implanting encapsulated biological material with a growth factor and conjugate into a patient...
US20080293626 Pigment epithelium-derived factor as a therapeutic agent for vascular leakage  
The present invention relates to method of treating a patient with a condition involving increased vascular permeability or increased angiogenesis comprising administering to the patient a...
US20070110775 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same  
The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of an aptamer and to methods for treating or preventing a condition in an...
US20080025962 Remedy for Alzheimer's Disease  
The present invention provides a prophylactic/therapeutic agent for Alzheimer's disease comprising a substance that inhibits the action of β-amyloid 1-40 to suppress vascular endothelial precursor...
US20070105769 Methods of treating tissue defects  
Methods of treating tissue defects, including defects such as bone fractures, vertebrae fusions, and spinal disc repair, using electric or electromagnetic fields and growth factors. In various...
US20050130929 System and method for the pretreatment of the endplates of an intervertebral disc  
A method for the pre-treatment of an intervertebral disc prior to the introduction of a disc prosthesis or implant includes removing at least a portion of the nucleus pulposus of the...
US20060281678 Novel inhibitor of angiogenesis, tumor progression, and metastasis targeting ras signalling pathway  
The present invention relates to a novel use of thymosin β10 protein for anti-angiogenesis, anti-tumor progression, and anti-metastasis by targeting a Ras signaling pathway. Particularly, thymosin...
US20120323310 GAMMA-TOCOPHEROL THERAPY FOR RESTENOSIS PREVENTION  
The present invention is directed to a drug eluting stent system, including: a stent; a tocopherol agent coupled to the stent; wherein the stent is adapted to elute the tocopherol agent into a...
US20110039772 NOVEL USES OF VEGFXXXB  
The invention provides VEGFxxxb, or an agent which selectively promotes the expression of VEGFxxxb in preference to VEGFxxx in cells of a subject or in vitro, or an expression vector system which...
US20070161081 Hepatocyte growth factor intron fusion proteins  
Isoforms of ligands, including isoforms of hepatocyte growth factor (HGF) containing an intron-encoded portion, and pharmaceutical compositions containing HGF isoforms are provided. The HGF ligand...
US20070265197 ELASTIN-LIKE POLYMER DELIVERY VEHICLES  
In invention concerns elastin-like polymer (ELP) delivery compositions and methods for the use thereof. In some aspects ELP compositions may be used to deliver therapeutic nucleic acids,...
US20060122117 Method of treating retinopathies and disorders associated with blood vessel loss  
The present invention provides a method of treating or preventing retinopathy in an individual in need thereof, comprising administering to said individual an effective amount of an agonist of...
US20070191273 Modulation of angiogenesis  
This invention relates to compounds, compositions, and methods for the treatment of traits, diseases and conditions that respond to the modulation of angiogenic growth factor bioavailability or...
US20110144013 VEGF-D Mutants and Their Use  
The present invention is a VEGF-D protein, containing one or more amino acid mutations at the dimer interface, and their use in therapy, particularly in the promotion of angiogenesis.
US20100143346 Treatment of Macular Degeneration  
An agent having progesterone antagonist properties may be used to treat eye conditions associated with pathological blood vessel formation, for example age-related macular degeneration, choroidal...
US20050175584 Functionalized colloidal metal compositions and methods  
The present invention comprises methods and compositions for making functionalized/reactive colloidal metal compositions and the uses thereof. The present invention comprises compositions and...
US20070155658 NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND STABLE DOUBLE-STRANDED RNA  
Nanoparticles of double-stranded nucleic acid complexed about a complexing agent such as the melamine derivatives of formulae I and II, preferably forming a trimeric nucleic acid complex. In...
US20060148691 Sustained release preparation for therapy of coronary stenosis or obstruction  
A pharmaceutical composition for therapy of coronary artery narrowing or blockage, which comprises a sustained release preparation containing an angiogenesis factor or a gene encoding the same and...
US20060240014 Methods and compounds for the treatment of vascular stenosis  
This invention features a method of treatment for vascular stenosis or restenosis using a combination of N-phenyl-2-pyrimidine derivatives such as imatinib mesylate and PI3K inhibitors, such as...
US20070190107 Cell selective implant surface with controlled release of bioactive agents  
The present invention relates to an implant (1) with at least partially a roughened surface (2), which is at least partially covered by an organic or polymeric intermediate layer (3) and attached...
US20080057028 Vegf-C or Vegf-D Materials and Methods for Stimulation of Neural Stem cells  
The present invention relates to VEGF-C or VEGF-D materials and methods for promoting growth and differentiation of neural stem cells, neuronal and neuronal precursor cells, oligodendrocytes and...
US20060217311 VEGF antagonist formulations  
Formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a...
US20050096257 Combination therapy for the treatment of ocular neovascular disorders  
The invention features methods for treating a patient diagnosed with, or at risk of developing, a neovascular disorder by administering a PDGF antagonist and a VEGF antagonist to the patient. The...
US20070269411 Porous silicon materials and devices  
Provided are materials and devices comprising physiologically acceptable silicon. The materials and devices can comprise a vector, including a viral vector.
US20070264300 Therapeutic agent carrier and method of treating bone fractures  
A therapeutic agent carrier for treating a defect in a bone is disclosed and can include a body that can be configured to approximate a portion of the bone. Further, the therapeutic agent carrier...
US20080003198 Hernia treatment agents  
There are provided herniated disc treatment agents developed as a result of molecular level analysis of the action mechanism of spontaneous resorption of herniated disc. Angiogenesis-inducing...
US20060002978 Biodegradable scaffolds and uses thereof  
The invention is directed to scaffolds containing porous polymer material prepared by a process of gas foaming/particulate leaching and a wet granulation step prior to gas foaming and particulate...
US20060189534 Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same  
The present invention is directed to a method of inhibiting at least one of vascular leakage, angiogenesis, inflammation and fibrosis in an animal by administering to the animal an effective...
US20120157381 COMPOSITIONS AND METHODS FOR CARDIAC TISSUE REPAIR  
The invention features compositions comprising agents having cardiac protective activity isolated from epicardial progenitor cells and derivatives thereof, and methods for the use of such...
US20050175724 Composition for modulating a physiological reaction or inducing an immune response  
The present invention relates to a new composition, uses and method for modulating a physiological reaction or inducing an immune response after oral administration to a human or an animal of a...
US20130058926 METHOD FOR ALLEVIATING AND/OR PREVENTING SKIN REDDENING  
A method of alleviating and/or preventing skin reddening for a subject in need thereof by means of inhibiting angiogenesis at the site of the reddened skin, is provided.
US20110281799 Vascular Endothelial Growth Factor D (VEGF-D) Antibodies and Vectors, and Methods of Uses  
VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as...
US20140315803 METHODS FOR STIMULATING HAIR GROWTH  
A method for promoting hair growth in a human in need of promoting hair growth. The method includes preparing a composition comprising a therapeutically effective amount of at least three of: a...
US20130281369 METHODS FOR STIMULATING HAIR GROWTH  
A method for promoting hair growth in a human in need of promoting hair growth. The method includes preparing a composition comprising a therapeutically effective amount of at least three of: a...
US20060210532 Means and methods for the recruitment and identification of stem cells  
Described are methods of modulating stem/progenitor cell recruitment involving molecules that agonize the formation of plasmin stimulating the recruitment of stem/progenitor cells, including...
US20130040880 Novel Cytokine Containing Compositions  
The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing...
US20120322731 NOVEL CYTOKINE CONTAINING COMPOSITIONS  
The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing...
US20080085272 Silk-Based Drug Delivery System  
The present invention provides for novel sustained release silk-based delivery systems. The invention further provides methods for producing such formulations. In general, a silk fibroin solution...
US20070117750 METHOD FOR ENHANCED OCULAR DRUG PENETRATION  
Provided is a method for enhanced intraocular drug penetration that comprises the co-administration of ocular therapeutics with agents that increases the permeability of ocular and periocular...
US20070141139 COMPOSITION FOR INTESTINAL DELIVERY  
The present invention relates to a new composition, use and method for oral administration to a human or an animal of a physiologically active agent comprising neutralizing agents to increase pH...
US20120010138 NOVEL USES OF VEGFXXXB  
The invention provides VEGFxxxb, or an agent which selectively promotes the expression of VEGFxxxb in preference to VEGFxxx in cells of a subject or in vitro, or an expression vector system which...
US20110014197 METHODS OF TREATING PRE-ECLAMPSIA OR ECLAMPSIA  
Disclosed herein are methods for treating pre-eclampsia and eclampsia using compounds that increase VEGF or PlGF levels or compounds that decrease sFlt-1 levels. Compounds that inhibit the binding...
US20130095060 PHARMACEUTICAL COMPOSITION FOR PROMOTING ARTERIOGENESIS, AND PREPARATION METHOD AND APPLICATIONS FOR THE SAME  
The present invention relates to a pharmaceutical composition for promoting arteriogenesis, and preparation method and applications of the same, wherein said pharmaceutical composition comprises...
US20050032697 Heparin binding VEGFR-3 ligands  
The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-3 ligand and a heparin binding domain. The chimeric molecules of the...
US20110142792 Compositions for Increasing Polypeptide Stability and Activity, and Related Methods  
This disclosure provides peptides, polypeptides, fusion polypeptides, compositions, and methods for enhancing or increasing the stability of a polypeptide (e.g., Taq polymerase). Such peptides,...
US20050214377 Microparticles for cell delivery  
The invention relates to microparticles and compositions containing the microparticles for use in delivering viable cells to specific regions in the body for treatment of diseases in the body, and...
US20140179601 FGF-9 AND ITS USE RELATING TO BLOOD VESSELS  
There is provided a composition for controlling formation and/or stabilization of a blood vessel comprising a first isolated nucleic acid molecule that encodes a FGF-9 polypeptide and optionally...
US20110319327 Polypeptides Homologous to VEGF and BMP1  
The present invention involves the identification and preparation of vascular endothelial growth factor-E (VEGF-E). VEGF-E is a novel polypeptide related to vascular endothelial growth factor...